Sstr1 - somatostatin receptor 1 Gene

Rattus norvegicus

Also known as Gpcrrna

Gene ID: 25033 | Gene type: protein coding

About Sstr1

Primary_assembly 6: 75,832,530-75,836,802 forward strand.mRatBN7.2:CM026979.1

This gene has 1 transcript (splice variant), 160 orthologues, 14 paralogues and is associated with 5 phenotypes. Biased expression in Brain (RPKM 54.5) and Lung (RPKM 13.9).

Summary

Enables Somatostatin Receptor activity. Involved in several processes, including brain development; cellular response to estradiol stimulus; and spermatogenesis. Located in cytoplasm and plasma membrane. Orthologous to human SSTR1 (Somatostatin Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sstr1 Products(1)

mRNA	Protein	Name
NM_012719.2	NP_036851.1	somatostatin receptor type 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables somatostatin receptor activity	IMP IMP: Inferred from mutant phenotype	1400442	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to estradiol stimulus	IEP IEP: Inferred from expression pattern	9564833	RGD
involved in cerebellum development	IEP IEP: Inferred from expression pattern	9166718	RGD
involved in forebrain development	IEP IEP: Inferred from expression pattern	10805921	RGD
involved in response to starvation	IEP IEP: Inferred from expression pattern	7956902	RGD
involved in spermatogenesis	IEP IEP: Inferred from expression pattern	9421433	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Sstr1 Protein Structure

7tmA_SSTR1

0
100
200
300
391 a.a.

Protein Preferred Names

Protein Names

somatostatin receptor type 1

RNGPCRRNA	SRIF-2
SS-1-R	SS1-R
SS1R	Somatostatin receptor subtype 1

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-105172	TT-232	Agonist	98.27%	Phase 2

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P1932	Cortistatin-14		99.21%	Unkown
HY-P1201	Cyclosomatostatin	Antagonist	99.76%	Unkown
HY-P4452	PRL 2915	Antagonist	99.57%	Unkown
HY-P1206	CH 275	Agonist	99.71%	Unkown
HY-P3618	Cortistatin-29 (reduced)		98.12%	Unkown
HY-P4469	PRL 3195	Antagonist	/	Unkown
HY-P2150	Cortistatin-29		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sstr1	NCBI	NCBI:6751

Name
Email *

	Sorry, but the email address you supplied was invalid.