Map1a - microtubule-associated protein 1A Gene

Rattus norvegicus

Also known as Mtap1a

Gene ID: 25152 | Gene type: protein coding

About Map1a

Summary

Enables actin binding activity; collagen binding activity; and microtubule binding activity. Involved in negative regulation of microtubule depolymerization. Located in several cellular components, including axon; dendrite; and neuronal cell body. Part of microtubule associated complex. Biomarker of hypothyroidism. Orthologous to human MAP1A (microtubule associated protein 1A). [provided by Alliance of Genome Resources, Apr 2022]

Map1a Products(1)

mRNA	Protein	Name
NM_030995.2	NP_112257.2	microtubule-associated protein 1A

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables actin binding	IDA IDA: Inferred from direct assay	11896150	RGD
enables collagen binding	IPI IPI: Inferred from physical interaction	11418592	RGD
enables microtubule binding	IDA IDA: Inferred from direct assay	9627185	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	7908909	RGD
enables structural constituent of presynapse	IDA IDA: Inferred from direct assay	18971475	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of microtubule depolymerization	IDA IDA: Inferred from direct assay	11896150	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in axon	IDA IDA: Inferred from direct assay	9627185	RGD
located in cytoplasm	IDA IDA: Inferred from direct assay	2509111	RGD
located in dendrite	IDA IDA: Inferred from direct assay	9627185	RGD
located in dendritic branch	IDA IDA: Inferred from direct assay	2509111	RGD
located in dendritic shaft	IDA IDA: Inferred from direct assay	2509111	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	18971475	RGD
part of microtubule associated complex	IDA IDA: Inferred from direct assay	7908909	RGD
located in neuron projection	IDA IDA: Inferred from direct assay	9627185	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	9627185	RGD
is active in postsynaptic density	IDA IDA: Inferred from direct assay	18971475	RGD
is active in presynaptic active zone	IDA IDA: Inferred from direct assay	18971475	RGD
located in primary dendrite	IDA IDA: Inferred from direct assay	2509111	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

microtubule-associated protein 1A

MAP-1A

Map1a Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Map1a	P34926	Dlg4	Rattus norvegicus	P31016	Filter Binding	9786987
Intra	Map1a	P34926	Dlg4	Rattus norvegicus	P31016	Fluorescence Spectr	17220895
Intra	Map1a	P34926	Dlg4	Rattus norvegicus	P31016	Pull Down	9786987
Intra	Map1a	P34926	Dlg4	Rattus norvegicus	P31016	Far-WB	9786987
Intra	Map1a	P34926	Dlg4	Rattus norvegicus	P31016	Y2H	9786987
Intra	Map1a	P34926	Dlg1	Rattus norvegicus	Q62696	Pull Down	9786987
Intra	Map1a	P34926	Dlg2	Rattus norvegicus	Q63622	Anti Bait CoIP	9786987
Intra	Map1a	P34926	Dlg2	Rattus norvegicus	Q63622	IF	9786987

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08026	MAP1A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Map1a	NCBI	NCBI:4130

Name
Email *

	Sorry, but the email address you supplied was invalid.