SNX32 - sorting nexin 32 Gene

Homo sapiens

Also known as SNX6B

Gene ID: 254122 | Gene type: protein coding

About SNX32

This gene has 9 transcripts (splice variants), 154 orthologues and 15 paralogues. Biased expression in brain (RPKM 2.1), testis (RPKM 1.0) and 7 other tissues.

Summary

Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be located in cytosol. Predicted to be active in endosome. [provided by Alliance of Genome Resources, Apr 2022]

SNX32 Products(1)

mRNA	Protein	Name
NM_152760.3	NP_689973.2	sorting nexin-32

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21516116	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNX32 Protein Structure

Vps5

0
100
200
300
403 a.a.

Protein Preferred Names

Protein Names

sorting nexin-32

sorting nexin-6B

SNX32 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SNX32	Q86XE0	SNX2	Homo sapiens	O60749	Y2H Array	32296183
Intra	SNX32	Q86XE0	SNX2	Homo sapiens	O60749	Y2H Prey Pooling	32296183
Intra	SNX32	Q86XE0	SNX2	Homo sapiens	O60749	Anti Tag CoIP	33961781
Intra	SNX32	Q86XE0	SNX2	Homo sapiens	O60749	Anti Tag CoIP	28514442
Intra	SNX32	Q86XE0	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	32296183
Intra	SNX32	Q86XE0	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	32296183
Intra	SNX32	Q86XE0	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	32296183
Intra	SNX32	Q86XE0	SPANXB1	Homo sapiens	Q9NS25	Validated Y2H	32296183
Intra	SNX32	Q86XE0	SNX1	Homo sapiens	Q13596	Anti Tag CoIP	28514442
Intra	SNX32	Q86XE0	SNX1	Homo sapiens	Q13596	Y2H Prey Pooling	32296183
Intra	SNX32	Q86XE0	SNX1	Homo sapiens	Q13596	Y2H Array	32296183
Intra	SNX32	Q86XE0	SNX1	Homo sapiens	Q13596	Anti Tag CoIP	33961781
Intra	SNX32	Q86XE0	MNS1	Homo sapiens	Q8NEH6	Validated Y2H	32296183
Intra	SNX32	Q86XE0	NME7	Homo sapiens	Q9Y5B8	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Amyotrophic Lateral Sclerosis 7

ALS7	Amyotrophic Lateral Sclerosis Type 7

Retinitis Pigmentosa 39

RP39	Retinitis Pigmentosa, Type 39

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13541	SNX32 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SNX32	VGNC	VGNC:65555
Canis familiaris	SNX32	VGNC	VGNC:46639
Rattus norvegicus	SNX32	RGD	RGD:1560591
Macaca mulatta	SNX32	VGNC	VGNC:77777
Mus musculus	SNX32	MGD	MGI:2444704

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