SSC5D - scavenger receptor cysteine rich family member with 5 domains Gene

Homo sapiens

Also known as S5D-SRCRB

Gene ID: 284297 | Gene type: protein coding

About SSC5D

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:55,488,436-55,519,099 (from NCBI)

This gene has 5 transcripts (splice variants), 397 orthologues and 15 paralogues. Broad expression in gall bladder (RPKM 7.3), endometrium (RPKM 6.2) and 21 other tissues.

Summary

Predicted to enable fibronectin binding activity; laminin binding activity; and scavenger receptor activity. Predicted to be involved in defense response; detection of Bacterial lipoprotein; and negative regulation of interleukin-8 production. Predicted to act upstream of or within regulation of interleukin-8 production. Predicted to be located in collagen-containing extracellular matrix. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

SSC5D Products(2)

mRNA	Protein	Name
NM_001144950.2	NP_001138422.1	soluble scavenger receptor cysteine-rich domain-containing protein SSC5D isoform 1 precursor
NM_001195267.2	NP_001182196.1	soluble scavenger receptor cysteine-rich domain-containing protein SSC5D isoform 2 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SSC5D Protein Structure

SRCR

0
300
600
900
1200
1573 a.a.

Protein Preferred Names

Protein Names

soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

Related Diseases

Diseases

Alias

Nasal Type Extranodal Nk/T-Cell Lymphoma

Extranodal Nasal Nk/T Cell Lymphoma	Angiocentric T-Cell Lymphoma
Lethal Midline Granuloma	Nk/T-Cell Lymphoma
Nktcl	Nasal T/Natural Killer-Cell Lymphoma
Granuloma, Lethal Midline	Nasal And Nasal-Type Nk/T-Cell Lymphoma

Adenoiditis

Chronic Adenoiditis

Vitreous Detachment

Posterior Vitreous Detachment

Vitreous Syneresis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13808	SSC5D Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SSC5D	VGNC	VGNC:53993
Felis catus	SSC5D	VGNC	VGNC:82391
Mus musculus	SSC5D	MGD	MGI:3606211
Rattus norvegicus	SSC5D	RGD	RGD:1565772
Bos taurus	SSC5D	VGNC	VGNC:35310

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