2. Gene
  3. Tnik - TRAF2 and NCK interacting kinase Gene

Tnik - TRAF2 and NCK interacting kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1561817

Gene ID: 294917 | Gene type: protein coding

About Tnik

Primary_assembly 2: 111,184,387-111,580,750 forward strand.mRatBN7.2:CM026975.1

This gene has 6 transcripts (splice variants), 268 orthologues, 36 paralogues and is associated with 8 phenotypes.

Summary

Predicted to enable protein serine/threonine kinase activity. Involved in positive regulation of dendrite morphogenesis. Is active in glutamatergic synapse; postsynaptic density, intracellular component; and presynapse. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TNIK (TRAF2 and NCK interacting kinase). [provided by Alliance of Genome Resources, Apr 2022]

Tnik Products(1)

mRNA Protein Name
NM_001106422.1 NP_001099892.1 TRAF2 and NCK-interacting protein kinase
Protein Preferred Names Protein Names

TRAF2 and NCK-interacting protein kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100830 NCB-0846 Inhibitor 99.61% Unkown
HY-111754 DMX-5804 Inhibitor 99.83% Unkown
HY-10371 Pim1/AKK1-IN-1 Inhibitor 98.20% Unkown
HY-124745 KY-05009 99.24% Unkown
HY-145293 TNIK-IN-3 Inhibitor 99.88% Unkown
HY-160623 INS018 055 Inhibitor 99.38% Unkown
HY-124762 TNIK-IN-1 98.86% Unkown
HY-156816 ON 108600 Inhibitor 99.73% Unkown
HY-143437 TNIK-IN-5 Inhibitor 99.75% Unkown
HY-N3127 Orobol Inhibitor 99.28% Unkown
HY-156817 TNIK-IN-6 96.92% Unkown
HY-156818 TNIK-IN-7 99.90% Unkown
HY-156502 TINK-IN-1 Inhibitor 98.02% Unkown
HY-162314 TNIK-IN-8 Inhibitor / Unkown
HY-143436 TNIK-IN-4 Inhibitor / Unkown
HY-145292 TNIK-IN-2 99.68% Unkown
HY-156523 TNIK&MAP4K4-IN-1 / Unkown
HY-163478 TNIK-IN-9 Inhibitor / Unkown
HY-RS14831 TNIK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14832 Tnik Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14833 Tnik Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnik NCBI NCBI:23043