1. Gene
  2. APOH - apolipoprotein H Gene

APOH - apolipoprotein H Gene

Homo sapiens

Also known as BG; B2G1; B2GP1

Gene ID: 350 | Gene type: protein coding

About APOH

Cytogenetic location: 17q24.2 Genomic coordinates (GRCh38): 17:66,212,033-66,229,415 (from NCBI)

This gene has 4 transcripts (splice variants), 241 orthologues and 39 paralogues. Restricted expression toward liver (RPKM 3533.3).

Summary

Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I Antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019]

APOH Products(1)

mRNA Protein Name
NM_000042.3 NP_000033.2 beta-2-glycoprotein 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
18822289 GOA
enables lipid binding IDA
IDA: Inferred from direct assay
222615 GOA
enables lipoprotein lipase activator activity IDA
IDA: Inferred from direct assay
7417307 GOA
enables phospholipid binding IDA
IDA: Inferred from direct assay
15486070 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9269765 GOA
Biological Process GO Annotation Evidence Reference Source
involved in blood coagulation, intrinsic pathway IDA
IDA: Inferred from direct assay
4052628 GOA
involved in negative regulation of angiogenesis IDA
IDA: Inferred from direct assay
17872974 GOA
involved in negative regulation of blood coagulation IDA
IDA: Inferred from direct assay
4052628 GOA
involved in negative regulation of endothelial cell migration IDA
IDA: Inferred from direct assay
17872974 GOA
involved in negative regulation of endothelial cell proliferation IDA
IDA: Inferred from direct assay
17872974 GOA
involved in negative regulation of fibrinolysis IDA
IDA: Inferred from direct assay
14726399 GOA
involved in negative regulation of myeloid cell apoptotic process IDA
IDA: Inferred from direct assay
15534879 GOA
involved in negative regulation of smooth muscle cell apoptotic process IDA
IDA: Inferred from direct assay
15534879 GOA
involved in plasminogen activation IDA
IDA: Inferred from direct assay
16480936 GOA
involved in positive regulation of lipoprotein lipase activity IDA
IDA: Inferred from direct assay
7417307 GOA
involved in regulation of fibrinolysis IDA
IDA: Inferred from direct assay
16480936 GOA
involved in triglyceride metabolic process IDA
IDA: Inferred from direct assay
7417307 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
16480936 GOA
part of chylomicron IDA
IDA: Inferred from direct assay
222615 GOA
located in extracellular space IDA
IDA: Inferred from direct assay
15486070 GOA
part of high-density lipoprotein particle IDA
IDA: Inferred from direct assay
222615 GOA
part of very-low-density lipoprotein particle IDA
IDA: Inferred from direct assay
222615 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

APOH Protein Structure

Sushi

Sushi: Sushi repeat (SCR repeat) (23 - 75)

Sushi

Sushi: Sushi repeat (SCR repeat) (80 - 137)

Sushi

Sushi: Sushi repeat (SCR repeat) (142 - 200)

Sushi

Sushi: Sushi repeat (SCR repeat) (205 - 260)

Sushi_2

Sushi_2: Beta-2-glycoprotein-1 fifth domain (261 - 345)

  • 0
  • 100
  • 200
  • 300
  • 345 a.a.
Protein Preferred Names Protein Names

beta-2-glycoprotein 1

APC inhibitor

Recombinant APOH Proteins

Cat. No. Product Name Accession Purity
HY-P7533 Apolipoprotein H/APOH Protein, Human (HEK293, His) P02749 (G20-C345) ≥95%

Related Diseases

Diseases Alias
Antiphospholipid Syndrome

Antiphospholipid Antibody Syndrome

Hughes Syndrome

Familial Antiphospholipid Syndrome

Aps

Lupus Anticoagulant, Familial

Anti-Phospholipid Syndrome

Apls

Classic Apls

Classic Antiphospholipid Syndrome

Acromegaloid Facial Appearance Syndrome

Anticardiolipin Syndrome

Syphilis

Chancre

Syphilitic Chancre

Retinal Artery Occlusion

Retina Artery Narrowing

Retinal Artery Spasm

Spasm Of Ophthalmic Artery

Retinal Spasm

Vasospasm Of Retina

Sneddon Syndrome

Livedo Reticularis And Cerebrovascular Accidents

SNDNS

Ehrmann-Sneddon Syndrome

Livedo Racemosa-Cerebrovascular Accident Syndrome

Livedo Reticularis-Cerebrovascular Accident Syndrome

Sneddon'S Syndrome

Idiopathic Livedo Reticularis With Systemic Involvement

Cerebro-Vascular Lesions And Livedo Reticularis

Livedo Racemosa And Cerebrovascular Accidents

Thrombosis

Thrombosis Of Blood Vessel

Transverse Myelitis

Myelitis Transverse

Myelitis, Transverse

Retinal Vascular Occlusion

Retinal Vasc. Occlusion

Occlusion Of Retinal Vessels

Retinal Obstruction

Hepatic Infarction

Infarct Of Liver

Hepatic Infarct

Liver Infarct

Liver Infarction

Protein S Deficiency

Protein S Deficiency Disease

Hereditary Thrombophilia Due To Protein S Deficiency

Central Retinal Vein Occlusion

Crvo

Buerger Disease

Thromboangiitis Obliterans

Buerger'S Disease

Presenile Gangrene

Inflammatory Occlusive Peripheral Vascular Disease

Occlusive Peripheral Vascular Disease

Tao

Endarteritis Obliterans

Retinal Vein Occlusion

Occlusion, Of Retinal Vein

Heart Valve Disease

Heart Valve Diseases

Valvular Heart Disease

Valvular Heart Diseases

Heart Valve Prolapse

Vasculitis

Angiitis

Autoimmune Vasculitis

Systemic Vasculitis

Vasculitis, Autoimmune

Protein C Deficiency

Hereditary Thrombophilia Due To Protein C Deficiency

Proc Deficiency

Congenital Thrombotic Disease, Due To Protein C Deficiency

Pulmonary Embolism

Pulmonary Artery Embolism

Pulmonary Embolus

Pulmonary Emboli

Budd-Chiari Syndrome

Hepatic Vein Thrombosis

Chiari Syndrome

BDCHS

Membranous Obstruction Of The Inferior Vena Cava

Budd-Chiari Syndrome, Somatic

Movc

Budd-Chiari Syndrome, Susceptibility To, Somatic

Budd-Chiari Syndrome, Susceptibility To

Membranous Obstruction Of Inferior Vena Cava

Hepatic Vein Block

Obstruction Of Hepatic Veins

Hepatic Vein Obstruction

Hepatic Venous Block

Splenic Infarction

Splenic Infarct

Splenic Infarcts

Infarct Of The Spleen

Acanthamoeba Keratitis
Thrombophilia Due To Activated Protein C Resistance

Activated Protein C Resistance

Apc Resistance

THPH2

Thrombophilia Due To Deficiency Of Activated Protein C Cofactor

Proc Cofactor Deficiency

Pccf Deficiency

Thrombophilia V

Thrombophilia, Susceptibility To, Due To Factor V Leiden

Thrombophilia Due To Factor V Leiden

Thrombophilia 2 Due To Activated Protein C Resistance

Thrombophilia, Susceptibility To, Due To Activated Protein C Resistance

Factor Xii Deficiency

Hageman Factor Deficiency

Haf Deficiency

Factor Xii Deficiency Disease

F12 Deficiency

Deficiency, Hageman

Coagulation Factor 12 Deficiency

Factor 12 Deficiency

Congenital Factor Xii Deficiency

Congenital Hageman Factor Deficiency

FA12D

Factor Xii

Deficiency, Factor Xii

Thrombophilia

Hypercoagulability State

Intracranial Thrombosis

Cerebral Thrombosis

Thrombosis Of Cerebral Veins

Cerebral Arterial Thrombosis

Autoimmune Disease Of Cardiovascular System
Collagen Disease

Collagen Diseases

Collagen Disorder

Papilledema

Choked Disk

Edema Of The Optic Disc

Raynaud Disease

Raynaud'S Disease

Raynaud Phenomenon

Raynaud'S Syndrome

Raynaud'S

Cold Fingers, Hereditary

Raynaud'S Phenomenon

Raynaud'S Disease/Phenomenon

Raynauds Syndrome

Raynauds Phenomenon

Secondary Raynaud'S Phenomenon

Raynaud Syndrome

Malignant Atrophic Papulosis

Degos Disease

Kohlmeier-Degos Disease

Papulosis Atrophican Maligna

Papulosis, Malignant Atrophic

Atrophic Papulosis, Malignant

Degos'S Malignant Atrophic Papulosis

Köhlmeier-Degos Disease

Köhlmeier-Degos-Delort-Tricort Syndrome

Kohlmeier-Degos-Delort-Tricort Syndrome

Placenta Disease

Placenta Diseases

Placenta Disorder

Pregnancy Complications

Placenta Disorders

Retinal Vasculitis
Antithrombin Iii Deficiency

Hereditary Antithrombin Deficiency

Congenital Antithrombin Iii Deficiency

Hereditary Thrombophilia Due To Congenital Antithrombin Deficiency

AT3D

Thrombophilia Due To Antithrombin Iii Deficiency

Thph7

Hereditary Thrombophilia Due To Congenital Antithrombin 3 Deficiency

Thrombophilia 7 Due To Antithrombin Iii Deficiency

At Iii Deficiency

Congenital At-Iii Deficiency

Inherited Antithrombin Deficiency

Antithrombin 3 Deficiency

Antithrombin Deficiency

Antithrombin-Iii Deficiency

At-Iii Deficiency

Thrombophilia Due To Antithrombin-Iii Deficiency

Hellp Syndrome

Hemolysis, Elevated Liver Enzymes, Lowered Platelets

Hemolysis, Elevated Liver Enzymes, Low Platelets In Pregnancy

Hemolysis-Elevated Liver Enzymes-Low Platelets Syndrome

Hellp - [Syndrome Of Haemolysis, Elevated Liver Enzymes And Low Platelet]

Haemolysis-Elevated Liver Enzymes-Low Platelet Count Syndrome

Hyperhomocysteinemia
Autoimmune Disease

Autoimmune Diseases

Autoimmune Hypersensitivity Disease

Hypersensitivity Reaction Type Ii Disease

Type Ii Hypersensitivity Reaction Disease

Stroke, Ischemic

Cerebral Infarction

Stroke

Ischemic Stroke

Cerebrovascular Accident

Cerebral Infarction, Susceptibility To

Stroke, Ischemic, Susceptibility To

Cerebral Infarct

Ischemic Stroke, Susceptibility To

Stroke, Susceptibility To

Cva - Cerebral Infarction

ISCHSTR

Ischemic Cerebrovascular Accident

Severe Pre-Eclampsia

Severe Preeclampsia

Antepartum Severe Pre-Eclampsia

Postpartum Severe Pre-Eclampsia

Severe Pre-Eclampsia, With Delivery

Severe Toxemia

Severe Pre-Eclampsia, Antepartum Condition Or Complication

Severe Pre-Eclampsia, Postpartum Condition Or Complication

Severe Puerperal Pre-Eclampsia

Severe Pre-Eclamptic Toxaemia

Severe Pet - [Pre-Eclamptic Toxaemia]

Thrombophilia Due To Thrombin Defect

Venous Thromboembolism

Venous Thrombosis

Thrombophilia Due To Factor 2 Defect

Thromboembolism

THPH1

Thromboembolism, Susceptibility To

Venous Thromboembolism, Susceptibility To

Venous Thrombosis, Protection Against

Prothrombin-Related Thrombophilia

Hyperprothrombinemia

Venous Thrombosis, Susceptibility To

Thrombophilia 1 Due To Thrombin Defect

F2-Related Thrombophilia

Factor Ii-Related Thrombophilia

Prothrombin 20210g>A Thrombophilia

Prothrombin G20210a Thrombophilia

Prothrombin Thrombophilia

Myelitis

Spinal Cord Inflammation Nos

Radiculomyelitis Nos

Myeloradiculitis

Lupus Erythematosus

Lupus

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus, Systemic

Subacute Cutaneous Lupus

Le - [Lupus Erythematosus]

Sjogren Syndrome

Sicca Syndrome

Sjogren'S Syndrome

Sjögren Syndrome

Sjogren-Gougerot Syndrome

Keratoconjunctivitis Sicca

Sjögren'S Syndrome

Xerodermosteosis

Dacryosialoadenopathia Atrophicans

Gougerot-Houwer-Sjogren Syndrome

Gougerot-Sjogren Syndrome

Keratoconjunctivitis Sicca-Xerostomia

Secreto-Inhibitor-Xerodermostenosis

Primary Sjogren Syndrome

Primary Sjogren-Gougerot Syndrome

Sjogrens Syndrome Primary

Sjogrens Syndrome

Dry Eye Syndromes

Portal Vein Thrombosis

Phlebitis Of Portal Vein

Deep Vein Thrombosis Of Portal Vein

Portal Thrombosis

Pvt - [Portal Vein Thrombosis]

Portal Venous Thrombosis

Portal Venous Embolism

Portal Venous Obstruction

Portal Venous Block

Portal Vein Embolism

Portal Vein Block

Portal Obstruction

Portal Embolism

Portal Block

Hepatic Portal Vein Obstruction

Occlusion Of Hepatic Portal Vein

Portal Vein Obstruction

Thrombophlebitis

Phlebitis And Thrombophlebitis Of Superficial Vessels Of Lower Extremities

Superficial Thrombophlebitis Of Leg

Thrombophlebitis Of A Superficial Leg Vein

Thrombophlebitis Of Superficial Veins Of Lower Extremity

Libman-Sacks Endocarditis

Libmann-Sachs, Endocarditis In Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]

Pregnancy Loss, Recurrent 1

Pregnancy Loss, Recurrent, Susceptibility To, 1

Rpl

RPRGL1

Rprgl

Recurrent Miscarriage

Recurrent Spontaneous Abortion

Abortion, Spontaneous, Recurrent

Fetal Loss, Recurrent

Fetal Loss, Recurrent, Susceptibility To

Miscarriage, Recurrent

Embryonic Loss, Recurrent

Stillbirth, Recurrent

Pregnancy Loss, Recurrent, 1

Recurrent Embryonic Loss

Recurrent Fetal Loss

Recurrent Stillbirth

Spontaneous Recurrent Abortion

Miscarriage Recurrent

Pregnancy Loss, Recurrent, Susceptibility To, Type 1

Abortion, Habitual

Polyarteritis Nodosa

Polyarteritis

Periarteritis Nodosa

Pan

Periarteritis

Kussmaul-Maier Disease

Panarteritis Nodosa

Kussmaul Disease

Pan - [Polyarteritis Nodosa]

Polyangiitis

Panangiitis

Arteritis Nodosa

Transient Cerebral Ischemia

Transient Ischemic Attack

Transient Ischemic Attacks

Tia

Tia - Transient Ischaemic Attack

Transient Cerebral Ischaemia

Ischemic Attack, Transient

Intermittent Cerebral Ischemia

Tia - [Transient Ischaemic Attack]

Intermittent Cerebral Ischaemia

Transient Cerebral Ischaemic Attack, Unspecified, Course Of Resolution Unspecified

Intracranial Hypertension

Raised Intracranial Pressure

Pre-Eclampsia

Preeclampsia

Gestational Hypertension

Hypertension Induced By Pregnancy

Pre-Eclamptic Toxaemia

Pregnancy Associated Hypertension

Proteinuric Hypertension Of Pregnancy

Hypertension, Pregnancy-Induced, Susceptibility To

Preeclampsia/Eclampsia

Pregnancy Toxemia

Toxaemia Of Pregnancy

Gestational Proteinuric Hypertension

Pregnancy-Induced Hypertension

Toxemia Of Pregnancy

Preeclampsia, Susceptibility To

Transient Hypertension Of Pregnancy

Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria

Gestational Hypertension Nos

Mild Proteinuric Hypertension Of Pregnancy

Pih - [Pregnancy-Induced Hypertension]

Pregnancy-Induced Hypertension Nos

Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria

Pe - [Pre-Eclampsia]

Pre-Eclampsia Nos

Pre-Eclamptic Nos

Pregnancy Pre-Eclampsia

Puerperal Pre-Eclampsia

Pre-Eclampsia Toxaemia

Toxaemia In Pregnancy

Pet - [Pre-Eclamptic Toxaemia]

Maternal Toxaemia

Prothrombin Deficiency, Congenital

Dysprothrombinemia

Hypoprothrombinemia

Congenital Factor Ii Deficiency

Prothrombin Deficiency

Factor Ii Deficiency

Congenital Prothrombin Deficiency

FA2D

Hypoprothrombinemias

Inherited Factor Ii Deficiency

Hereditary Factor Ii Deficiency Disease

Thrombotic Thrombocytopenic Purpura

Purpura, Thrombotic Thrombocytopenic

Ttp

Thrombotic Thrombocytopenic Purpura, Acquired

Idiopathic Thrombotic Thrombocytopenic Purpura

Moschcowitz Disease

Moschcowitz'S Syndrome

Moschowitz Syndrome

Chronic Relapsing Thrombotic Thrombocytopenic Purpura

Familial Thrombotic Thrombocytopenia Purpura

Moschkowitz Disease

Purpura Thrombotic Thrombocytopenic

Familial Thrombotic Thrombocytopenic Purpura

Microangiopathic Hemolytic Anemia

Congenital Thrombotic Thrombocytopenic Purpura

Autoimmune Thrombotic Thrombocytopenic Purpura

Ttp - [Thrombotic Thrombocytopenic Purpura]

Moschcowitz Syndrome

Vascular Disease

Vascular Diseases

Aneurysm

Spinal Cord Ischemia

Vascular Anomaly

Spinal Cord Vascular Diseases

Vascular Tissue Disease

Endocarditis
Autoimmune Atherosclerosis
Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Pyoderma Gangrenosum

Phagedenic Pyoderma

Phagedena Geometric

Pyoderma
Discoid Lupus Erythematosus

Lupus Erythematosus Discoid

Lupus Erythematosus, Discoid

Cdle - [Chronic Discoid Lupus Erythematosus]

Dle - [Discoid Lupus Erythematosus]

Chronic Discoid Lupus Erythematosus

Discoid Lupus Nos

Purpura

Purpuric Disorder

Patent Foramen Ovale

Atrial Septal Defect Within Oval Fossa

Foramen Ovale Patent

Ostium Secundum Atrial Septal Defect

Atrial Septal Defect, Ostium Secundum Type

Foramen Ovale, Patent

Defect, Patent Or Persistent, Ostium Secundum

Ostium Secundum Type Atrial Septal Defect

Persistent Ostium Secundum

Asd Ostium Secundum Type

Ostium Secundum Asd

Osasd

Asd, Ostium Secundum Type

Pfo - [Patent Foramen Ovale]

Open Foramen Ovale

Open Oval Foramen

Persistent Foramen Ovale

Secundum Atrial Septal Defect

Mixed Connective Tissue Disease

Sharp Syndrome

Mctd

Connective Tissue Disease Overlap Syndrome

Mixed Collagen Vascular Disease

Mctd - [Mixed Connective Tissue Disease]

Legg-Calve-Perthes Disease

Perthes Disease

LCPD

Coxa Plana

Legg-Perthes Disease

Juvenile Osteochondrosis Of Hip And Pelvis

Pseudocoxalgia

Legg-Calvé-Perthes Disease

Lcp

Calve - Perthes' Disease

Juvenile Osteochond-Hip/Pelvis

Juvenile Osteochondrosis Of Hip And/Or Pelvis

Legg-Calve-Perthes Symptom

Osteochondrosis Of Legg-Calve-Perthes

Perthe'S Disease

Legg-Calve-Perthes Syndrome

Osteochondritis Deformans

Calve-Perthes Disease

Aseptic Necrosis Of The Capital Femoral Epiphysis

Osteochondrosis Of The Capital Femoral Epiphysis

Legg-Calvé-Perthes Syndrome

Avascular Necrosis Of The Capital Femoral Epiphysis

Eclampsia

Eclampsia In Puerperium

Postpartum Eclampsia

Eclampsia, Postpartum

Puerperal Eclampsia

Intermittent Claudication

Charcot'S Syndrome

Amyotrophic Lateral Sclerosis

Cerebrovascular Disease

Cerebrovascular Disorder

Cerebrovascular Accident

Cerebrovascular Disorders

Cva

Stroke

Connective Tissue Disease

Connective Tissue Diseases

Connective Tissue Disorder

Abnormality Of Connective Tissue

Disorder Of Connective Tissue

Connective Tissue Disorders

Behcet Syndrome

Behcet Disease

Behcet'S Syndrome

Behcet'S Disease

Behçet Disease

Bd

Adamantiades-Behcet Disease

Triple Symptom Complex

Behçet'S Disease

Behet'S Syndrome

Bd Syndrome

Behçet Syndrome

Behçet'S Syndrome

Behcet Triple Symptom Complex

Malignant Aphthosis

Old Silk Route Disease

Adamantiades-Behçet Disease

Migraine With Or Without Aura 1

Migraine

Migraine With Or Without Aura, Susceptibility To, 1

Migraine Disorder

Migraine Variant

Migraines

Migraine Disorders

Mgr1

Mgau

Ma

Migraine With Or Without Aura

Classic Migraine

Common Migraine

Disorder, Migraine

Headache Migraine

Headache Migrainous

Migraine Headache

Migraine Syndrome

Headache Including Migraine

Migraine, Susceptibility To

Livedoid Vasculitis

Livedoid Vasculopathy

Livedo Reticularis With Summer Ulcerations

Livedo Vasculitis

Livedo Reticularis With Winter Ulcerations

Segmental Hyalinizing Vasculopathy

Milian Atrophie Blanche

Segmental Hyalinizing Vasculitis

Livedo Reticularis With Summer Ulceration

Hemolytic Anemia

Anemia, Hemolytic

Anemia Hemolytic

Anaemia Due To Other Disorders Of Glutathione Metabolism

Chronic Non Spherocytic Anaemia

G6pd - [Glucose-6-Phosphate Dehydrogenase Deficiency] Anaemia

Anaemia Due To Glucose-6-Phosphate Dehydrogenase Deficiency

Glucose-6-Phosphate Dehydrogenase Deficiency With Anaemia

Glucose-6-Phosphate Dehydrogenase Deficiency Anaemia

Favism Anaemia

Haemolytic Anaemia Due Tog6pd Deficiency

Favism

Pentose Phosphate Pathway Disorder Anaemia

Anaemia Due To Pentose Phosphate Pathway Defect

Thoracic Outlet Syndrome

Tos

Tos - Thoracic Outlet Syndrome

Thoracic Outlet Syndromes

Thoracic Outlet Compression Syndrome

Branch Retinal Artery Occlusion

Retinal Artery Occlusion

Arterial Retinal Branch Occlusion

Retinal Arterial Branch Occlusion

Heart Block, Congenital

Congenital Heart Block

Heart Block Congenital

Congenital Atrioventricular Block

Nonbacterial Thrombotic Endocarditis

Non-Bacterial Thrombotic Endocarditis

Marantic Endocarditis

Non-Infective Endocarditis

Puerperal Pulmonary Embolism

Obstetric Pulmonary Embolism

Prothrombin Deficiency

Factor Ii Deficiency

Hypoprothrombinemia

Dysprothrombinemia

Deficiency, Prothrombin

Inherited Factor Ii Deficiency

Hereditary Factor Ii Deficiency Disease

Mononeuritis Multiplex
Cerebritis
Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis

Mononeuritis Of Upper Limb And Mononeuritis Multiplex
Pulmonary Artery Disease

Abnormality Of The Pulmonary Artery

Sagittal Sinus Thrombosis

Thrombosis Of Superior Longitudinal Sinus

Thrombosis Of Superior Sagittal Sinus

Thrombosis Superior Sagittal Sinus

Evans' Syndrome

Evans Syndrome

Autoimmune Hemolytic Anemia And Autoimmune Thrombocytopenia

Evan Syndrome

Immune Pancytopenia

Evan'S Syndrome

Blood Coagulation Disease

Blood Coagulation Disorders

Coagulation Protein Disease

Inherited Blood Coagulation Disease

Postpartum Coagulation Defect

Postpartum Coagulation Defect With Delivery

Coagulation Protein Disorders

Puerperal Coagulopathy

Intracranial Sinus Thrombosis

Sinus Thrombosis, Intracranial

Placental Abruption

Abruptio Placentae

Abruptio Placenta

Abortion, Threatened

Threatened Miscarriage

Haemorrhage Specified As Due To Threatened Abortion

Spontaneous Threatened Abortion

Anemia, Autoimmune Hemolytic

Autoimmune Hemolytic Anemia

Idiopathic Autoimmune Hemolytic Anemia

Immuno-Hemolytic Anemia

Anemia, Hemolytic, Autoimmune

Autoimmune Haemolytic Anaemia

Autoimmune Hemolytic Anaemia

Acquired Autoimmune Hemolytic Anemia

Anemia Hemolytic Autoimmune

Familial Auto-Immune Hemolytic Anemia

Aha

Aiha

Cardiomyopathy, Dilated, 1m

Dilated Cardiomyopathy 1m

CMD1M

Cardiomyopathy, Dilated 1m

Cardiomyopathy, Dilated, Type 1m

Blood Platelet Disease

Platelet Disorder

Blood Platelet Disorders

Thrombocytopathy

Platelet Dysfunction

Platelet Disorders

Qualitative Platelet Deficiency

Malaria

Malaria, Susceptibility To

Malaria, Resistance To

Malaria, Cerebral

Cerebral Malaria

Malaria, Severe, Susceptibility To

Malaria, Severe, Resistance To

Malaria, Cerebral, Susceptibility To

Induced Malaria

Malaria, Vivax, Protection Against

Malaria, Severe

Malaria, Cerebral, Reduced Risk Of

Malaria, Protection Against

Resistance To Malaria Due To G6pd Deficiency

Malaria Due To G6pd Deficiency

Malarial Encephalitis

CM

Malaria Cerebral

Susceptibility To Malaria

Acute Pernicious Fever

Aestivo-Autumnal Fever

Aestivo Autumnal Malaria

Chagres Fever

Continued Malaria Fever

Estivo-Autumnal Fever

Estivo-Autumnal Malaria

Estivo-Autumnal Malarial Fever

Falciparum Fever

Malignant Tertian Fever

Malignant Tertian Malaria

Pernicious Intermittent Fever

Pernicious Malaria

Quotidian Malaria

Subtertian Fever

Subtertian Malaria Fever

Subtertian Malignant Tertian Malaria

Tropical Malaria

Algid Malaria

Bilious Haemoglobinuric Fever

Black Water Fever

Blackwater Fever

Malarial Blackwater Fever

Severe Malarial Falciparum

West African Fever

Malarial Haematinuria

Haemoglobinuric Fever

Haemoglobinuric Malaria

Severe Plasmodium Falciparum Malaria

Malarial Haemoglobinuria

Malarial Haematuria

Falciparum Malaria [Malignant Tertian]

Malaria Tropica

Malarial Shock

Chagres Virus Disease

Malignant Malaria

Mtm - [Malignant Tertian Malaria]

Tm -[Malignant Tertian Malaria]

Panama Fever

St - [Subtertian Malaria]

Malarial Quotidian

Benign Tertian Malaria

Tertian Ague

Vivax Fever

Plasmodium Vivax Malaria Nos

Btm - [Benign Tertian Malaria]

Bt - [Benign Tertian Malaria]

Vivax Malaria

Benign Tertian Vivax Malaria

Tertian Malaria

Quartan Malaria

Quartan Ague

Quartan Fever

Plasmodium Malariae Malaria Nos

Quartan Malarial

Malaria By Plasmodium Malariae

Malariae Malaria

Ovale Tertian Malaria

Plasmodium Ovale Fever

Malaria Fever By Plasmodium Ovale

Ovale Malaria

Malaria By Plasmodium Ovale

Malarial Ovale

Marsh Fever

Remittent Congestive Fever

Coastal Fever

Remittent Gastric Fever

Miasmatic Fever

Congestive Remittent Fever

Intermittent Fever

Jungle Fever

Paludism

Cameroon Fever

Ague

Corsican Fever

Intermittent Bilious Fever

Disease Due To Plasmodiidae

Malarial Fever

Plasmodiosis

Remittent Fever

Roman Fever

Malaria Fever Nos

Malaria Nos

Paludal Fever

Clinically Diagnosed Malaria

Clinically Diagnosed Malaria Without Parasitological Confirmation

Congestive Fever

Malarial Cachexia

Marsh Cachexia

Paludal Cachexia

Recurrent Malaria

Remittent Malaria

Myocardial Infarction

Heart Attack

Myocardial Infarction, Susceptibility To

Myocardial Infarction 1

Myocardial Infarction, Protection Against

Myocardial Infarction, Decreased Susceptibility To

Myocardial Infarction, Decreased

Myocardial Infarct

MCI1

Premature Myocardial Infarction

Myocardial Infarction, Susceptibility To, Type 1

Alpha-2-Plasmin Inhibitor Deficiency

Plasmin Inhibitor Deficiency

Antiplasmin Deficiency

Antiplasmin Defiency

Anti-Plasmin Deficiency, Congenital

Antiplasmin Deficiency, Congenital

Congenital Alpha2-Antiplasmin Deficiency

APLID

Congenital Alpha2 Antiplasmin Deficiency

Choreatic Disease

Chorea

Hereditary Chorea

Cerebral Palsy

Infantile Cerebral Palsy

Mixed Cerebral Palsy

Palsy Cerebral

Palsy, Cerebral

Cerebral Palsy, Mixed

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris APOH VGNC VGNC:38004
Felis catus APOH VGNC VGNC:67853
Bos taurus APOH VGNC VGNC:26032
Rattus norvegicus APOH RGD RGD:1310625
Macaca mulatta APOH VGNC VGNC:104579
Mus musculus APOH MGD MGI:88058
Macaca fascicularis APOH NCBI NCBI:102134518
Others APOH NCBI