GRXCR1 - glutaredoxin and cysteine rich domain containing 1 Gene

Homo sapiens (human)

Also known as DFNB25; PPP1R88

Gene ID: 389207 | Gene type: protein coding

About GRXCR1

Summary

This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010]

GRXCR1 Products(1)

mRNA	Protein	Name
NM_001080476.3	NP_001073945.1	glutaredoxin domain-containing cysteine-rich protein 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

glutaredoxin domain-containing cysteine-rich protein 1

glutaredoxin, cysteine rich 1

protein phosphatase 1, regulatory subunit 88

GRXCR1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	GRXCR1	A8MXD5	CAP2	Homo sapiens	P40123	Y2H Prey Pooling	32296183
Intra	GRXCR1	A8MXD5	CAP2	Homo sapiens	P40123	Validated Y2H	32296183
Intra	GRXCR1	A8MXD5	CAP2	Homo sapiens	P40123	Y2H Array	32296183
Intra	GRXCR1	A8MXD5	PRDM6	Homo sapiens	Q9NQX0	Y2H Prey Pooling	32296183
Intra	GRXCR1	A8MXD5	PRDM6	Homo sapiens	Q9NQX0	Validated Y2H	32296183
Intra	GRXCR1	A8MXD5	PRDM6	Homo sapiens	Q9NQX0	Y2H Array	32296183
Intra	GRXCR1	A8MXD5	TEX11	Homo sapiens	Q8IYF3-3	Y2H Prey Pooling	32296183
Intra	GRXCR1	A8MXD5	TEX11	Homo sapiens	Q8IYF3-3	Y2H Array	32296183
Intra	GRXCR1	A8MXD5	TEX11	Homo sapiens	Q8IYF3-3	Validated Y2H	32296183
Intra	GRXCR1	A8MXD5	ALAS1	Homo sapiens	P13196	Validated Y2H	32296183
Intra	GRXCR1	A8MXD5	ALAS1	Homo sapiens	P13196	Y2H Array	32296183
Intra	GRXCR1	A8MXD5	ALAS1	Homo sapiens	P13196	Y2H Prey Pooling	32296183
Intra	GRXCR1	A8MXD5	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	32296183
Intra	GRXCR1	A8MXD5	INCA1	Homo sapiens	Q0VD86	Validated Y2H	32296183
Intra	GRXCR1	A8MXD5	INCA1	Homo sapiens	Q0VD86	Y2H Array	32296183
Intra	GRXCR1	A8MXD5	SDCBP	Homo sapiens	O00560	Validated Y2H	32296183
Intra	GRXCR1	A8MXD5	PICK1	Homo sapiens	Q9NRD5	Y2H Prey Pooling	32296183
Intra	GRXCR1	A8MXD5	PICK1	Homo sapiens	Q9NRD5	Validated Y2H	32296183
Intra	GRXCR1	A8MXD5	PICK1	Homo sapiens	Q9NRD5	Y2H Array	32296183
Intra	GRXCR1	A8MXD5	SNX32	Homo sapiens	Q86XE0	Y2H Prey Pooling	32296183
Intra	GRXCR1	A8MXD5	SNX32	Homo sapiens	Q86XE0	Validated Y2H	32296183
Intra	GRXCR1	A8MXD5	SNX32	Homo sapiens	Q86XE0	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

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