2. Gene
  3. ERG28 - ergosterol biosynthesis 28 homolog Gene

ERG28 - ergosterol biosynthesis 28 homolog Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NET51; C14orf1

Gene ID: 11161 | Gene type: protein coding

About ERG28

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:75,649,791-75,660,876 (from NCBI)

This gene has 1 transcript (splice variant) and 203 orthologues. Broad expression in testis (RPKM 53.5), liver (RPKM 25.7) and 25 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in sterol biosynthetic process. Located in transport vesicle. [provided by Alliance of Genome Resources, Apr 2022]

ERG28 Products(1)

mRNA Protein Name
NM_007176.4 NP_009107.1 ergosterol biosynthetic protein 28 homolog
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ERG28 Protein Structure

Erg28

Erg28: Erg28 like protein (6 - 115)

  • 0
  • 100
  • 140 a.a.
Protein Preferred Names Protein Names

ergosterol biosynthetic protein 28 homolog

probable ergosterol biosynthetic protein 28

ERG28 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra ERG28 Q9UKR5 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
Intra ERG28 Q9UKR5 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 JAGN1 Homo sapiens Q8N5M9
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 JAGN1 Homo sapiens Q8N5M9
Y2H Array
32296183
Intra ERG28 Q9UKR5 SGPL1 Homo sapiens O95470
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 SGPL1 Homo sapiens O95470
Y2H Array
32296183
Intra ERG28 Q9UKR5 HSD17B11 Homo sapiens Q8NBQ5
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 HSD17B11 Homo sapiens Q8NBQ5
Y2H Array
32296183
Intra ERG28 Q9UKR5 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra ERG28 Q9UKR5 KCNJ6 Homo sapiens P48051
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 KCNJ6 Homo sapiens P48051
Y2H Array
32296183
Intra ERG28 Q9UKR5 STOM Homo sapiens P27105
Y2H Array
32296183
Intra ERG28 Q9UKR5 STOM Homo sapiens P27105
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 FXYD3 Homo sapiens Q14802-3
Y2H Array
32296183
Intra ERG28 Q9UKR5 FXYD3 Homo sapiens Q14802-3
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 CD74 Homo sapiens P04233-2
Y2H Array
32296183
Intra ERG28 Q9UKR5 CD74 Homo sapiens P04233-2
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra ERG28 Q9UKR5 NDUFA3 Homo sapiens O95167
Y2H Array
32296183
Intra ERG28 Q9UKR5 NDUFA3 Homo sapiens O95167
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 AQP2 Homo sapiens P41181
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 AQP2 Homo sapiens P41181
Y2H Array
32296183
Intra ERG28 Q9UKR5 MS4A3 Homo sapiens Q96HJ5
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 MS4A3 Homo sapiens Q96HJ5
Y2H Array
32296183
Intra ERG28 Q9UKR5 SLC34A2 Homo sapiens O95436-2
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 SLC34A2 Homo sapiens O95436-2
Y2H Array
32296183
Intra ERG28 Q9UKR5 SLC26A6 Homo sapiens Q9BXS9-3
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 SLC26A6 Homo sapiens Q9BXS9-3
Y2H Array
32296183
Intra ERG28 Q9UKR5 TLCD4 Homo sapiens Q96MV1
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 TLCD4 Homo sapiens Q96MV1
Y2H Array
32296183
Intra ERG28 Q9UKR5 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra ERG28 Q9UKR5 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra ERG28 Q9UKR5 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 NCR3LG1 Homo sapiens Q68D85
Y2H Array
32296183
Intra ERG28 Q9UKR5 NCR3LG1 Homo sapiens Q68D85
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 LYPD5 Homo sapiens Q6UWN5
Y2H Array
32296183
Intra ERG28 Q9UKR5 LYPD5 Homo sapiens Q6UWN5
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 SCN3B Homo sapiens Q9NY72
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 SCN3B Homo sapiens Q9NY72
Y2H Array
32296183
Intra ERG28 Q9UKR5 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra ERG28 Q9UKR5 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra ERG28 Q9UKR5 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
Intra ERG28 Q9UKR5 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra ERG28 Q9UKR5 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 CLDN5 Homo sapiens O00501
Y2H Array
32296183
Intra ERG28 Q9UKR5 CLDN5 Homo sapiens O00501
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 ELOVL4 Homo sapiens Q9GZR5
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 ELOVL4 Homo sapiens Q9GZR5
Y2H Array
32296183
Intra ERG28 Q9UKR5 FAM174A Homo sapiens Q8TBP5
Y2H Array
32296183
Intra ERG28 Q9UKR5 GET1 Homo sapiens O00258
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 GET1 Homo sapiens O00258
Y2H Array
32296183
Intra ERG28 Q9UKR5 AQP3 Homo sapiens Q92482
Y2H Array
32296183
Intra ERG28 Q9UKR5 AQP3 Homo sapiens Q92482
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
Intra ERG28 Q9UKR5 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra ERG28 Q9UKR5 GPR37L1 Homo sapiens O60883
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 GPR37L1 Homo sapiens O60883
Y2H Array
32296183
Intra ERG28 Q9UKR5 MFSD14B Homo sapiens Q5SR56
Y2H Array
32296183
Intra ERG28 Q9UKR5 MFSD14B Homo sapiens Q5SR56
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 GJB5 Homo sapiens O95377
Y2H Array
32296183
Intra ERG28 Q9UKR5 GJB5 Homo sapiens O95377
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra ERG28 Q9UKR5 TMEM106A Homo sapiens Q96A25
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 TMEM106A Homo sapiens Q96A25
Y2H Array
32296183
Intra ERG28 Q9UKR5 PIGY Homo sapiens Q3MUY2
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 PIGY Homo sapiens Q3MUY2
Y2H Array
32296183
Intra ERG28 Q9UKR5 SAR1A Homo sapiens Q9NR31
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 SAR1A Homo sapiens Q9NR31
Y2H Array
32296183
Intra ERG28 Q9UKR5 MRM1 Homo sapiens Q6IN84
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 MRM1 Homo sapiens Q6IN84
Y2H Array
32296183
Intra ERG28 Q9UKR5 TM4SF19 Homo sapiens Q96DZ7
Y2H Array
32296183
Intra ERG28 Q9UKR5 TM4SF19 Homo sapiens Q96DZ7
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 CD53 Homo sapiens P19397
Y2H Array
32296183
Intra ERG28 Q9UKR5 CD53 Homo sapiens P19397
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra ERG28 Q9UKR5 ccsb orf id: 13502 Homo sapiens EBI-23641393
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 ccsb orf id: 2260 Homo sapiens EBI-22326698
Y2H Array
32296183
Intra ERG28 Q9UKR5 ccsb orf id: 2260 Homo sapiens EBI-22326698
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 ccsb orf id: 13502 Homo sapiens EBI-23641393
Y2H Array
32296183
Intra ERG28 Q9UKR5 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 STX1A Homo sapiens Q16623
Y2H Array
32296183
Intra ERG28 Q9UKR5 PDZK1IP1 Homo sapiens Q13113
Y2H Array
32296183
Intra ERG28 Q9UKR5 PDZK1IP1 Homo sapiens Q13113
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 MGST3 Homo sapiens O14880
Y2H Array
32296183
Intra ERG28 Q9UKR5 MGST3 Homo sapiens O14880
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 CLDN7 Homo sapiens O95471
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 CLDN7 Homo sapiens O95471
Y2H Array
32296183
Intra ERG28 Q9UKR5 BCL2L13 Homo sapiens Q9BXK5
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 BCL2L13 Homo sapiens Q9BXK5
Y2H Array
32296183
Intra ERG28 Q9UKR5 REEP4 Homo sapiens Q9H6H4
Y2H Array
32296183
Intra ERG28 Q9UKR5 REEP4 Homo sapiens Q9H6H4
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 MTERF3 Homo sapiens Q96E29
Y2H Array
32296183
Intra ERG28 Q9UKR5 MTERF3 Homo sapiens Q96E29
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 CYB561 Homo sapiens P49447
Y2H Array
32296183
Intra ERG28 Q9UKR5 CYB561 Homo sapiens P49447
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 MSMO1 Homo sapiens Q15800
Y2H Prey Pooling
32296183
Intra ERG28 Q9UKR5 MSMO1 Homo sapiens Q15800
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Ceroid Lipofuscinosis, Neuronal, 8, Northern Epilepsy Variant

Northern Epilepsy

Neuronal Ceroid Lipofuscinosis 8 Northern Epilepsy Variant

Epmr

Progressive Epilepsy-Intellectual Disability Syndrome, Finnish Type

Northern Epilepsy Syndrome

Epilepsy, Progressive, With Mental Retardation

Northern Epilepsy Variant, Neuronal Ceroid Lipofuscinosis, Northern Epilepsy Variant

Progressive Epilepsy With Mental Retardation, Northern Epilepsy

Cln8 Disease, Northern Epilepsy Variant

Ncl, Northern Epilepsy Variant

Neuronal Ceroid Lipofuscinosis, Northern Epilepsy Variant

CLN8NE

Ceroid Lipofuscinosis, Neuronal, 8
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04492 ERG28 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ERG28 RGD RGD:1310769
Bos taurus ERG28 VGNC VGNC:55113
Canis familiaris ERG28 VGNC VGNC:40449
Macaca mulatta ERG28 VGNC VGNC:72261
Felis catus ERG28 VGNC VGNC:61938
Mus musculus ERG28 MGD MGI:1915571