2. Gene
  3. TEX264 - testis expressed 264, ER-phagy receptor Gene

TEX264 - testis expressed 264, ER-phagy receptor Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ZSIG11

Gene ID: 51368 | Gene type: protein coding

About TEX264

This gene has 16 transcripts (splice variants) and 180 orthologues. Ubiquitous expression in testis (RPKM 25.1), kidney (RPKM 16.6) and 25 other tissues.

Summary

Enables signaling receptor activity. Involved in protein-DNA covalent cross-linking repair. Acts upstream of or within reticulophagy. Located in several cellular components, including autophagosome membrane; endoplasmic reticulum membrane; and replication fork. [provided by Alliance of Genome Resources, Apr 2022]

TEX264 Products(6)

mRNA Protein Name
NM_001129884.3 NP_001123356.1 testis-expressed protein 264 isoform 1
NM_001243725.2 NP_001230654.1 testis-expressed protein 264 isoform 1
NM_001243726.2 NP_001230655.1 testis-expressed protein 264 isoform 1
NM_001243727.3 NP_001230656.1 testis-expressed protein 264 isoform 2
NM_001278195.2 NP_001265124.1 testis-expressed protein 264 isoform 1
NM_015926.6 NP_057010.1 testis-expressed protein 264 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables signaling receptor activity IDA
IDA: Inferred from direct assay
31006538 GOA
Biological Process GO Annotation Evidence Reference Source
involved in protein-DNA covalent cross-linking repair IDA
IDA: Inferred from direct assay
32152270 GOA
acts upstream of or within reticulophagy IDA
IDA: Inferred from direct assay
31006538 GOA
involved in reticulophagy IMP
IMP: Inferred from mutant phenotype
31006537 GOA
Cellular Component GO Annotation Evidence Reference Source
located in autophagosome membrane IDA
IDA: Inferred from direct assay
31006537 GOA
located in cytosol IDA
IDA: Inferred from direct assay
32152270 GOA
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
31006537 GOA
located in nucleus IDA
IDA: Inferred from direct assay
32152270 GOA
located in replication fork IDA
IDA: Inferred from direct assay
32152270 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TEX264 Protein Structure

GyrI-like

GyrI-like: GyrI-like small molecule binding domain (45 - 184)

  • 0
  • 100
  • 200
  • 313 a.a.
Protein Preferred Names Protein Names

testis-expressed protein 264

testis expressed gene 264

TEX264 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
TEX264 Q9Y6I9 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 MS4A3 Homo sapiens Q96HJ5
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 MS4A3 Homo sapiens Q96HJ5
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 OPRM1 Homo sapiens P35372-10
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 OPRM1 Homo sapiens P35372-10
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 SLC34A2 Homo sapiens O95436-2
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 SLC34A2 Homo sapiens O95436-2
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 TM4SF18 Homo sapiens Q96CE8
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 TM4SF18 Homo sapiens Q96CE8
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 GJB1 Homo sapiens P08034
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 GJB1 Homo sapiens P08034
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 FFAR3 Homo sapiens O14843
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 FFAR3 Homo sapiens O14843
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 ADGRG3 Homo sapiens Q86Y34
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 ADGRG3 Homo sapiens Q86Y34
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 LHFPL4 Homo sapiens Q7Z7J7
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 LHFPL4 Homo sapiens Q7Z7J7
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 SLC10A2 Homo sapiens Q12908
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 SLC10A2 Homo sapiens Q12908
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 TSPAN12 Homo sapiens O95859
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 TSPAN12 Homo sapiens O95859
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 CERS4 Homo sapiens Q9HA82
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 CERS4 Homo sapiens Q9HA82
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 EMP1 Homo sapiens P54849
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 EMP1 Homo sapiens P54849
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 CLN6 Homo sapiens Q9NWW5
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 CLN6 Homo sapiens Q9NWW5
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 COQ9 Homo sapiens O75208
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 COQ9 Homo sapiens O75208
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 CLDN2 Homo sapiens P57739
Y2H Prey Pooling
32296183
Intra
TEX264 Q9Y6I9 CLDN2 Homo sapiens P57739
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 TMEM79 Homo sapiens Q9BSE2
Y2H Array
31515488
Intra
TEX264 Q9Y6I9 TMEM79 Homo sapiens Q9BSE2
Validated Y2H
25416956
Intra
TEX264 Q9Y6I9 TMEM79 Homo sapiens Q9BSE2
Y2H Array
32296183
Intra
TEX264 Q9Y6I9 TMEM79 Homo sapiens Q9BSE2
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Hereditary Sensory And Autonomic Neuropathy Type 1

Hereditary Sensory And Autonomic Neuropathy Type I

Hereditary Sensory Neuropathy-Deafness-Dementia Syndrome

Hsan1e

Hsan1

Dnmt1-Related Dementia, Deafness, And Sensory Neuropathy

Hsn1e

Hsnie

Hereditary Sensory Neuropathy Type Ie

Hereditary Sensory Neuropathy-Sensorineural Hearing Loss-Dementia Syndrome

Hereditary Sensory And Autonomic Neuropathy Type Ie

Hereditary Sensory And Autonomic Neuropathy Type 1e

Hereditary Sensory Neuropathy With Hearing Loss And Dementia

Dnmt1-Complex Disorder

Hereditary Sensory And Autonomic Neuropathy Type 1 With Dementia And Hearing Loss

Hsn Ie

Hereditary Sensory Autonomic Neuropathy, Type 1

Hsan1- [Hereditary Sensory And Autonomic Neuropathy Type I]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14395 TEX264 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TEX264 VGNC VGNC:35765
Rattus norvegicus TEX264 RGD RGD:1359353
Macaca mulatta TEX264 VGNC VGNC:79841
Felis catus TEX264 VGNC VGNC:66099
Mus musculus TEX264 MGD MGI:1096570
Canis familiaris TEX264 VGNC VGNC:47271