2. Gene
  3. GPR42 - G protein-coupled receptor 42 Gene

GPR42 - G protein-coupled receptor 42 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as FFAR1L; FFAR3L; GPR41L; GPR42P

Gene ID: 2866 | Gene type: protein coding

About GPR42

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,371,068-35,372,962 (from NCBI)

This gene has 2 transcripts (splice variants), 339 orthologues and 15 paralogues.

Summary

Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPR42 Products(1)

mRNA Protein Name
NM_001348195.2 NP_001335124.1 G-protein coupled receptor 42
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
NOT enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
12496283 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Reference Source
NOT involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12496283 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR42 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (32 - 276)

  • 0
  • 100
  • 200
  • 300
  • 346 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 42

G protein-coupled receptor 42 pseudogene

GPR42 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra GPR42 O15529 RTP2 Homo sapiens Q5QGT7
Validated Y2H
32296183
Intra GPR42 O15529 TMEM182 Homo sapiens Q6ZP80
Validated Y2H
32296183
Intra GPR42 O15529 SLC30A8 Homo sapiens Q8IWU4
Validated Y2H
32296183
Intra GPR42 O15529 NRM Homo sapiens Q8IXM6
Y2H Array
32296183
Intra GPR42 O15529 NRM Homo sapiens Q8IXM6
Validated Y2H
32296183
Intra GPR42 O15529 CCL4L1 Homo sapiens Q8NHW4
Validated Y2H
32296183
Intra GPR42 O15529 SLC41A2 Homo sapiens Q96JW4
Validated Y2H
32296183
Intra GPR42 O15529 SLC30A3 Homo sapiens Q99726
Validated Y2H
32296183
Intra GPR42 O15529 DRAM1 Homo sapiens Q8N682
Validated Y2H
32296183
Intra GPR42 O15529 SLC38A7 Homo sapiens Q9NVC3
Validated Y2H
32296183
Intra GPR42 O15529 TMEM242 Homo sapiens Q9NWH2
Validated Y2H
32296183
Intra GPR42 O15529 NINJ2 Homo sapiens Q9NZG7
Validated Y2H
32296183
Intra GPR42 O15529 TEX264 Homo sapiens Q9Y6I9
Validated Y2H
32296183
Intra GPR42 O15529 TMBIM6 Homo sapiens P55061
Validated Y2H
32296183
Intra GPR42 O15529 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra GPR42 O15529 ADIPOQ Homo sapiens Q15848
Validated Y2H
32296183
Intra GPR42 O15529 ERMP1 Homo sapiens Q7Z2K6
Validated Y2H
32296183
Intra GPR42 O15529 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra GPR42 O15529 TMEM239 Homo sapiens Q8WW34-2
Validated Y2H
32296183
Intra GPR42 O15529 CLEC2D Homo sapiens Q9UHP7-3
Validated Y2H
32296183
Intra GPR42 O15529 CTXN3 Homo sapiens Q4LDR2
Validated Y2H
32296183
Intra GPR42 O15529 ATP13A1 Homo sapiens Q9HD20-3
Validated Y2H
32296183
Intra GPR42 O15529 ANKRD46 Homo sapiens Q86W74-2
Validated Y2H
32296183
Intra GPR42 O15529 LNPEP Homo sapiens Q9UIQ6-2
Validated Y2H
32296183
Intra GPR42 O15529 FXYD3 Homo sapiens Q14802-3
Validated Y2H
32296183
Intra GPR42 O15529 SYNGR1 Homo sapiens O43759-2
Validated Y2H
32296183
Intra GPR42 O15529 PLP1 Homo sapiens P60201-2
Validated Y2H
32296183
Intra GPR42 O15529 PLP1 Homo sapiens P60201-2
Y2H Array
32296183
Intra GPR42 O15529 TSPO2 Homo sapiens Q5TGU0
Validated Y2H
32296183
Intra GPR42 O15529 STRIT1 Homo sapiens P0DN84
Validated Y2H
32296183
Intra GPR42 O15529 LTC4S Homo sapiens Q16873
Validated Y2H
32296183
Intra GPR42 O15529 SLC41A1 Homo sapiens Q8IVJ1
Validated Y2H
32296183
Intra GPR42 O15529 NDUFB11 Homo sapiens Q9NX14
Validated Y2H
32296183
Intra GPR42 O15529 IL1RL1 Homo sapiens Q01638-2
Validated Y2H
32296183
Intra GPR42 O15529 SLC35E4 Homo sapiens Q6ICL7
Validated Y2H
32296183
Intra GPR42 O15529 SLC39A2 Homo sapiens Q9NP94
Validated Y2H
32296183
Intra GPR42 O15529 TREX1 Homo sapiens Q9NSU2-1
Validated Y2H
32296183
Intra GPR42 O15529 EFNA5 Homo sapiens P52803
Validated Y2H
32296183
Intra GPR42 O15529 ITGAM Homo sapiens P11215
Validated Y2H
32296183
Intra GPR42 O15529 SERINC1 Homo sapiens Q9NRX5
Validated Y2H
32296183
Intra GPR42 O15529 YIF1A Homo sapiens O95070
Validated Y2H
32296183
Intra GPR42 O15529 MS4A1 Homo sapiens P11836
Validated Y2H
32296183
Intra GPR42 O15529 LHFPL5 Homo sapiens Q8TAF8
Validated Y2H
32296183
Intra GPR42 O15529 MGAM Homo sapiens O43451
Validated Y2H
32296183
Intra GPR42 O15529 TMEM140 Homo sapiens Q9NV12
Validated Y2H
32296183
Intra GPR42 O15529 PMP22 Homo sapiens Q01453
Validated Y2H
32296183
Intra GPR42 O15529 TMEM60 Homo sapiens Q9H2L4
Validated Y2H
32296183
Intra GPR42 O15529 MFSD6 Homo sapiens Q6ZSS7
Validated Y2H
32296183
Intra GPR42 O15529 FAM3C Homo sapiens Q92520
Validated Y2H
32296183
Intra GPR42 O15529 GPR37L1 Homo sapiens O60883
Validated Y2H
32296183
Intra GPR42 O15529 TMEM147 Homo sapiens Q9BVK8
Validated Y2H
32296183
Intra GPR42 O15529 COMT Homo sapiens P21964
Validated Y2H
32296183
Intra GPR42 O15529 ATP6V0B Homo sapiens Q99437
Validated Y2H
32296183
Intra GPR42 O15529 ATP4B Homo sapiens P51164
Validated Y2H
32296183
Intra GPR42 O15529 ALOX5AP Homo sapiens P20292
Validated Y2H
32296183
Intra GPR42 O15529 GJB2 Homo sapiens P29033
Validated Y2H
32296183
Intra GPR42 O15529 CXCL9 Homo sapiens Q07325
Validated Y2H
32296183
Intra GPR42 O15529 CD300C Homo sapiens Q08708
Validated Y2H
32296183
Intra GPR42 O15529 MFSD5 Homo sapiens Q6N075
Validated Y2H
32296183
Intra GPR42 O15529 EMP1 Homo sapiens P54849
Validated Y2H
32296183
Intra GPR42 O15529 JPH1 Homo sapiens Q9HDC5
Validated Y2H
32296183
Intra GPR42 O15529 PAEP Homo sapiens P09466
Validated Y2H
32296183
Intra GPR42 O15529 NSG1 Homo sapiens P42857
Validated Y2H
32296183
Intra GPR42 O15529 TMEM65 Homo sapiens Q6PI78
Validated Y2H
32296183
Intra GPR42 O15529 FXYD6 Homo sapiens Q9H0Q3
Validated Y2H
32296183
Intra GPR42 O15529 TF Homo sapiens P02787
Validated Y2H
32296183
Intra GPR42 O15529 APOD Homo sapiens P05090
Validated Y2H
32296183
Intra GPR42 O15529 ZFPL1 Homo sapiens O95159
Validated Y2H
32296183
Intra GPR42 O15529 IGFBP5 Homo sapiens P24593
Validated Y2H
32296183
Intra GPR42 O15529 ATP6V0C Homo sapiens P27449
Validated Y2H
32296183
Intra GPR42 O15529 IER3IP1 Homo sapiens Q9Y5U9
Validated Y2H
32296183
Intra GPR42 O15529 SYNDIG1 Homo sapiens Q9H7V2
Validated Y2H
32296183
Intra GPR42 O15529 STX8 Homo sapiens Q9UNK0
Validated Y2H
32296183
Intra GPR42 O15529 STATH Homo sapiens P02808
Validated Y2H
32296183
Intra GPR42 O15529 TMEM19 Homo sapiens Q96HH6
Validated Y2H
32296183
Intra GPR42 O15529 SMIM3 Homo sapiens Q9BZL3
Validated Y2H
32296183
Intra GPR42 O15529 SERP2 Homo sapiens Q8N6R1
Validated Y2H
32296183
Intra GPR42 O15529 BNIP3 Homo sapiens Q12983
Validated Y2H
32296183
Intra GPR42 O15529 KLRG1 Homo sapiens Q96E93
Validated Y2H
32296183
Intra GPR42 O15529 LEPROTL1 Homo sapiens O95214
Validated Y2H
32296183
Intra GPR42 O15529 YIPF2 Homo sapiens Q9BWQ6
Validated Y2H
32296183
Intra GPR42 O15529 YIPF6 Homo sapiens Q96EC8
Validated Y2H
32296183
Intra GPR42 O15529 YIPF4 Homo sapiens Q9BSR8
Validated Y2H
32296183
Intra GPR42 O15529 GYPC Homo sapiens P04921
Validated Y2H
32296183
Intra GPR42 O15529 CD79A Homo sapiens P11912
Validated Y2H
32296183
Intra GPR42 O15529 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra GPR42 O15529 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra GPR42 O15529 YIPF1 Homo sapiens Q9Y548
Validated Y2H
32296183
Intra GPR42 O15529 LAT Homo sapiens O43561-2
Validated Y2H
32296183
Intra GPR42 O15529 KCNA1 Homo sapiens Q09470
Validated Y2H
32296183
Intra GPR42 O15529 RUSF1 Homo sapiens Q96GQ5
Validated Y2H
32296183
Intra GPR42 O15529 SMCO4 Homo sapiens Q9NRQ5
Validated Y2H
32296183
Intra GPR42 O15529 SLC30A2 Homo sapiens Q9BRI3
Validated Y2H
32296183
Intra GPR42 O15529 BTN2A2 Homo sapiens Q8WVV5
Validated Y2H
32296183
Intra GPR42 O15529 TM4SF4 Homo sapiens P48230
Validated Y2H
32296183
Intra GPR42 O15529 PNLIPRP1 Homo sapiens P54315
Validated Y2H
32296183
Intra GPR42 O15529 CCDC167 Homo sapiens Q9P0B6
Validated Y2H
32296183
Intra GPR42 O15529 TMEM30B Homo sapiens Q3MIR4
Validated Y2H
32296183
Intra GPR42 O15529 SLC38A1 Homo sapiens Q9H2H9
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05715 GPR42 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GPR42 MGD MGI:2685324