TMEM19 - transmembrane protein 19 Gene

Homo sapiens

Gene ID: 55266 | Gene type: protein coding

About TMEM19

This gene has 6 transcripts (splice variants) and 201 orthologues. Ubiquitous expression in kidney (RPKM 11.7), duodenum (RPKM 10.9) and 25 other tissues.

Summary

Predicted to be integral component of membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM19 Products(1)

mRNA	Protein	Name
NM_018279.4	NP_060749.2	transmembrane protein 19

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM19 Protein Structure

DUF92

0
100
200
300
336 a.a.

Protein Preferred Names

Protein Names

transmembrane protein 19

TMEM19 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TMEM19	Q96HH6	BSCL2	Homo sapiens	Q96G97-4	Y2H Array	31515488
Intra	TMEM19	Q96HH6	BSCL2	Homo sapiens	Q96G97-4	Y2H Prey Pooling	25416956
Intra	TMEM19	Q96HH6	BSCL2	Homo sapiens	Q96G97-4	Y2H Array	25416956
Intra	TMEM19	Q96HH6	PGRMC2	Homo sapiens	O15173	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	PGRMC2	Homo sapiens	O15173	Y2H Array	32296183
Intra	TMEM19	Q96HH6	TMEM45A	Homo sapiens	Q9NWC5	Y2H Array	32296183
Intra	TMEM19	Q96HH6	TMEM45A	Homo sapiens	Q9NWC5	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	TMEM45A	Homo sapiens	Q9NWC5	Validated Y2H	32296183
Intra	TMEM19	Q96HH6	PTGES	Homo sapiens	O14684	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	PTGES	Homo sapiens	O14684	Y2H Array	32296183
Intra	TMEM19	Q96HH6	BSCL2	Homo sapiens	J3KQ12	Y2H Array	32296183
Intra	TMEM19	Q96HH6	BSCL2	Homo sapiens	J3KQ12	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	GPX8	Homo sapiens	Q8TED1	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	GPX8	Homo sapiens	Q8TED1	Y2H Array	32296183
Intra	TMEM19	Q96HH6	TLCD4	Homo sapiens	Q96MV1	Y2H Array	32296183
Intra	TMEM19	Q96HH6	TLCD4	Homo sapiens	Q96MV1	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	TLCD4	Homo sapiens	Q96MV1	Validated Y2H	32296183
Intra	TMEM19	Q96HH6	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	TMEM19	Q96HH6	GPRC5D	Homo sapiens	Q9NZD1	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	GPRC5D	Homo sapiens	Q9NZD1	Validated Y2H	32296183
Intra	TMEM19	Q96HH6	GPRC5D	Homo sapiens	Q9NZD1	Y2H Array	32296183
Intra	TMEM19	Q96HH6	C10orf67	Homo sapiens	Q8IYJ2-2	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	C10orf67	Homo sapiens	Q8IYJ2-2	Y2H Array	32296183
Intra	TMEM19	Q96HH6	SERTM1	Homo sapiens	A2A2V5	Y2H Array	32296183
Intra	TMEM19	Q96HH6	SERTM1	Homo sapiens	A2A2V5	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	GJB1	Homo sapiens	P08034	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	GJB1	Homo sapiens	P08034	Y2H Array	32296183
Intra	TMEM19	Q96HH6	PIGP	Homo sapiens	P57054	Y2H Array	32296183
Intra	TMEM19	Q96HH6	PIGP	Homo sapiens	P57054	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	CPLX4	Homo sapiens	Q7Z7G2	Y2H Array	32296183
Intra	TMEM19	Q96HH6	CPLX4	Homo sapiens	Q7Z7G2	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Array	32296183
Intra	TMEM19	Q96HH6	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	GPR42	Homo sapiens	O15529	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	GPR42	Homo sapiens	O15529	Y2H Array	32296183
Intra	TMEM19	Q96HH6	LY6E	Homo sapiens	Q16553	Y2H Array	32296183
Intra	TMEM19	Q96HH6	LY6E	Homo sapiens	Q16553	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	ELOVL4	Homo sapiens	Q9GZR5	Y2H Array	32296183
Intra	TMEM19	Q96HH6	ELOVL4	Homo sapiens	Q9GZR5	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	ELOVL4	Homo sapiens	Q9GZR5	Validated Y2H	32296183
Intra	TMEM19	Q96HH6	FAM210B	Homo sapiens	Q96KR6	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	FAM210B	Homo sapiens	Q96KR6	Validated Y2H	32296183
Intra	TMEM19	Q96HH6	FAM210B	Homo sapiens	Q96KR6	Y2H Array	32296183
Intra	TMEM19	Q96HH6	TEX29	Homo sapiens	Q8N6K0	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	TEX29	Homo sapiens	Q8N6K0	Y2H Array	32296183
Intra	TMEM19	Q96HH6	RNF185	Homo sapiens	Q96GF1	Y2H Array	32296183
Intra	TMEM19	Q96HH6	RNF185	Homo sapiens	Q96GF1	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	CNR2	Homo sapiens	P34972	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	CNR2	Homo sapiens	P34972	Y2H Array	32296183
Intra	TMEM19	Q96HH6	SUSD6	Homo sapiens	Q92537	Y2H Array	32296183
Intra	TMEM19	Q96HH6	SUSD6	Homo sapiens	Q92537	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	MFSD14B	Homo sapiens	Q5SR56	Y2H Array	32296183
Intra	TMEM19	Q96HH6	MFSD14B	Homo sapiens	Q5SR56	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	GORAB	Homo sapiens	Q5T7V8	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	GORAB	Homo sapiens	Q5T7V8	Y2H Array	32296183
Intra	TMEM19	Q96HH6	APOA5	Homo sapiens	Q6Q788	Y2H Array	32296183
Intra	TMEM19	Q96HH6	APOA5	Homo sapiens	Q6Q788	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	SLC7A1	Homo sapiens	P30825	Y2H Array	32296183
Intra	TMEM19	Q96HH6	SLC7A1	Homo sapiens	P30825	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	CREB3L1	Homo sapiens	Q96BA8	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	CREB3L1	Homo sapiens	Q96BA8	Y2H Array	32296183
Intra	TMEM19	Q96HH6	LDAF1	Homo sapiens	Q96B96	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	LDAF1	Homo sapiens	Q96B96	Y2H Array	32296183
Intra	TMEM19	Q96HH6	TMEM139	Homo sapiens	Q8IV31	Y2H Array	32296183
Intra	TMEM19	Q96HH6	TMEM139	Homo sapiens	Q8IV31	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	BSCL2	Homo sapiens	Q96G97	Y2H Prey Pooling	25416956
Intra	TMEM19	Q96HH6	KASH5	Homo sapiens	Q8N6L0	Y2H Array	32296183
Intra	TMEM19	Q96HH6	KASH5	Homo sapiens	Q8N6L0	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	LEPROTL1	Homo sapiens	O95214	Y2H Array	32296183
Intra	TMEM19	Q96HH6	LEPROTL1	Homo sapiens	O95214	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	REEP4	Homo sapiens	Q9H6H4	Validated Y2H	32296183
Intra	TMEM19	Q96HH6	REEP4	Homo sapiens	Q9H6H4	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	REEP4	Homo sapiens	Q9H6H4	Y2H Array	32296183
Intra	TMEM19	Q96HH6	CD79A	Homo sapiens	P11912	Y2H Array	32296183
Intra	TMEM19	Q96HH6	CD79A	Homo sapiens	P11912	Y2H Prey Pooling	32296183
Intra	TMEM19	Q96HH6	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183
Intra	TMEM19	Q96HH6	TMEM14B	Homo sapiens	Q9NUH8	Validated Y2H	32296183
Intra	TMEM19	Q96HH6	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14691	TMEM19 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TMEM19	VGNC	VGNC:82259
Rattus norvegicus	TMEM19	RGD	RGD:735209
Mus musculus	TMEM19	MGD	MGI:1914476
Canis familiaris	TMEM19	VGNC	VGNC:47514
Bos taurus	TMEM19	VGNC	VGNC:36015
Felis catus	TMEM19	VGNC	VGNC:66301

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