FAM210B - family with sequence similarity 210 member B Gene

Homo sapiens

Also known as 5A3; C20orf108; dJ1167H4.1

Gene ID: 116151 | Gene type: protein coding

About FAM210B

Cytogenetic location: 20q13.2 Genomic coordinates (GRCh38): 20:56,358,974-56,368,663 (from NCBI)

This gene has 2 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 51.5), adrenal (RPKM 50.1) and 25 other tissues.

Summary

Involved in cellular response to estradiol stimulus and positive regulation of erythrocyte differentiation. Located in mitochondrial outer membrane. Is intrinsic component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

FAM210B Products(1)

mRNA	Protein	Name
NM_080821.3	NP_543011.2	protein FAM210B, mitochondrial

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to estradiol stimulus	IDA IDA: Inferred from direct assay	26968549	GOA
involved in positive regulation of erythrocyte differentiation	IMP IMP: Inferred from mutant phenotype	26968549	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in membrane	IDA IDA: Inferred from direct assay	26968549	GOA
located in mitochondrial outer membrane	IDA IDA: Inferred from direct assay	26968549	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FAM210B Protein Structure

DUF1279

0
100
192 a.a.

Protein Preferred Names

Protein Names

protein FAM210B, mitochondrial

transmembrane protein C20orf108

FAM210B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	FAM210B	Q96KR6	NINJ2	Homo sapiens	Q9NZG7	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	SERP1	Homo sapiens	Q9Y6X1	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	RPRM	Homo sapiens	Q9NS64	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	MFF	Homo sapiens	Q9GZY8-5	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	LPAR3	Homo sapiens	Q9UBY5	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	LNPEP	Homo sapiens	Q9UIQ6-2	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	HMOX1	Homo sapiens	P09601	Y2H Prey Pooling	32296183
Intra	FAM210B	Q96KR6	TMEM140	Homo sapiens	Q9NV12	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	FIS1	Homo sapiens	Q9Y3D6	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	ATP6V0B	Homo sapiens	Q99437	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	VKORC1	Homo sapiens	Q9BQB6	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	TIMMDC1	Homo sapiens	Q9NPL8	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	VAMP3	Homo sapiens	Q15836	Y2H Prey Pooling	32296183
Intra	FAM210B	Q96KR6	IER3IP1	Homo sapiens	Q9Y5U9	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	BCL2L13	Homo sapiens	Q9BXK5	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	SMCO4	Homo sapiens	Q9NRQ5	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	CCDC167	Homo sapiens	Q9P0B6	Validated Y2H	32296183
Intra	FAM210B	Q96KR6	UBE2J1	Homo sapiens	Q9Y385	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Ovarian Cancer

Ovarian Carcinoma	Ovarian Neoplasm
Malignant Tumour Of Ovary	Cancer Of The Ovary
Epithelial Ovarian Cancer	Neoplasm Of Ovary
Ovarian Neoplasms	Ovarian Cancers
Malignant Neoplasm Of Ovary	Primary Malignant Neoplasm Of Ovary
Ovarian Cancer, Somatic	Malignant Ovarian Tumor
Ovary Neoplasm	Primary Ovarian Cancer
Tumor Of The Ovary	Malignant Neoplasm Of The Ovary
Malignant Tumor Of The Ovary	Ovarian Malignant Tumor
OC	Ovarian Carcinomas
Cancer, Ovarian	Cancer Of Ovary
Ovary Cancer	Ca Ovary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04708	FAM210B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	FAM210B	VGNC	VGNC:28789
Macaca mulatta	FAM210B	VGNC	VGNC:72275
Canis familiaris	FAM210B	VGNC	VGNC:40658
Rattus norvegicus	FAM210B	RGD	RGD:1311378
Mus musculus	FAM210B	MGD	MGI:1914267

Name
Email *

	Sorry, but the email address you supplied was invalid.