CNOT11 - CCR4-NOT transcription complex subunit 11 Gene

Homo sapiens

Also known as C40; C2orf29

Gene ID: 55571 | Gene type: protein coding

About CNOT11

This gene has 3 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in testis (RPKM 19.6), placenta (RPKM 16.9) and 25 other tissues.

Summary

Predicted to be involved in mRNA catabolic process and negative regulation of translation. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2022]

CNOT11 Products(1)

mRNA	Protein	Name
NM_017546.5	NP_060016.3	CCR4-NOT transcription complex subunit 11

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	23232451	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of CCR4-NOT complex	IDA IDA: Inferred from direct assay	19558367	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CNOT11 Protein Structure

DUF2363

0
100
200
300
400
510 a.a.

Protein Preferred Names

Protein Names

CCR4-NOT transcription complex subunit 11

UPF0760 protein C2orf29

CNOT11 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CNOT11	Q9UKZ1	CNOT10	Homo sapiens	Q9H9A5	TAP	23232451
Intra	CNOT11	Q9UKZ1	CNOT10	Homo sapiens	Q9H9A5	Y2H	23232451
Intra	CNOT11	Q9UKZ1	CNOT10	Homo sapiens	Q9H9A5	Anti Tag CoIP	33961781
Intra	CNOT11	Q9UKZ1	CNOT1	Homo sapiens	A5YKK6	TAP	23232451
Intra	CNOT11	Q9UKZ1	CNOT1	Homo sapiens	A5YKK6	Anti Tag CoIP	33961781
Intra	CNOT11	Q9UKZ1	CNOT1	Homo sapiens	A5YKK6	Y2H	23232451
Cross	CNOT11	Q9UKZ1	Cnot7	Mus musculus	Q60809	Pull Down	23232451
Intra	CNOT11	Q9UKZ1	MEOX1	Homo sapiens	P50221	Y2H Array	32296183
Intra	CNOT11	Q9UKZ1	MEOX1	Homo sapiens	P50221	Y2H Prey Pooling	32296183
Intra	CNOT11	Q9UKZ1	FAM193B	Homo sapiens	Q96PV7	Y2H Prey Pooling	32296183
Intra	CNOT11	Q9UKZ1	FAM193B	Homo sapiens	Q96PV7	Y2H Array	32296183
Intra	CNOT11	Q9UKZ1	GPBP1L1	Homo sapiens	Q9HC44	Y2H Array	32296183
Intra	CNOT11	Q9UKZ1	GPBP1L1	Homo sapiens	Q9HC44	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Glioblastoma Mesenchymal Subtype

Cycloplegia

Ciliary Muscle Paresis	Cycloplegic Paralysis Of Accommodation
Paresis Of Accommodation	Visual Accommodation Paralysis
Accommodation Paralysis	Intrinsic Paralysis Of Eye Muscle
Cycloplegic

Eye Accommodation Disease

Lens Subluxation

Subluxation Of Lens

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02901	CNOT11 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CNOT11	VGNC	VGNC:71346
Felis catus	CNOT11	VGNC	VGNC:61027
Bos taurus	CNOT11	VGNC	VGNC:27516
Mus musculus	CNOT11	MGD	MGI:106580
Canis familiaris	CNOT11	VGNC	VGNC:39412
Rattus norvegicus	CNOT11	RGD	RGD:1560909

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