ZFP64 - ZFP64 zinc finger protein Gene

Homo sapiens

Also known as ZNF338

Gene ID: 55734 | Gene type: protein coding

About ZFP64

Cytogenetic location: 20q13.2 Genomic coordinates (GRCh38): 20:52,084,011-52,191,779 (from NCBI)

This gene has 12 transcripts (splice variants), 214 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 2.7), ovary (RPKM 2.2) and 25 other tissues.

Summary

Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in positive regulation of cytokine production and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of mRNA splicing, via spliceosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZFP64 Products(5)

mRNA	Protein	Name
NM_001319146.2	NP_001306075.1	zinc finger protein 64 isoform e
NM_018197.3	NP_060667.2	zinc finger protein 64 isoform a
NM_022088.5	NP_071371.3	zinc finger protein 64 isoform b
NM_199426.2	NP_955458.1	zinc finger protein 64 isoform c
NM_199427.3	NP_955459.2	zinc finger protein 64 isoform d

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	18430783	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in mesenchymal cell differentiation	IMP IMP: Inferred from mutant phenotype	18430783	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	27353377	GOA
located in megasporocyte nucleus	IDA IDA: Inferred from direct assay	27353377	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZFP64 Protein Structure

zf-C2H2_6

zf-H2C2_2

zf-H2C2_5

zf-C2H2_6

0
200
400
600
681 a.a.

Protein Preferred Names

Protein Names

zinc finger protein 64

zinc finger protein 338

ZFP64 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ZFP64	Q9NTW7	HEL164	Homo sapiens	V9HWH0	Validated Y2H	25416956
Intra	ZFP64	Q9NTW7	HEL164	Homo sapiens	V9HWH0	Y2H Prey Pooling	25416956
Intra	ZFP64	Q9NTW7	HEL164	Homo sapiens	V9HWH0	Y2H Array	25416956
Intra	ZFP64	Q9NTW7	MFAP1	Homo sapiens	P55081	Y2H Prey Pooling	25416956
Intra	ZFP64	Q9NTW7	BYSL	Homo sapiens	Q13895	Y2H Prey Pooling	25416956
Intra	ZFP64	Q9NTW7	BYSL	Homo sapiens	Q13895	Validated Y2H	25416956
Intra	ZFP64	Q9NTW7	BYSL	Homo sapiens	Q13895	Y2H Array	25416956
Intra	ZFP64	Q9NTW7	FHL2	Homo sapiens	Q14192	Validated Y2H	25416956
Intra	ZFP64	Q9NTW7	FHL2	Homo sapiens	Q14192	Y2H Array	31515488
Intra	ZFP64	Q9NTW7	FHL2	Homo sapiens	Q14192	Y2H Prey Pooling	25416956
Intra	ZFP64	Q9NTW7	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	ZFP64	Q9NTW7	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	ZFP64	Q9NTW7	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
Intra	ZFP64	Q9NTW7	TRIM41	Homo sapiens	Q8WV44	Validated Y2H	25416956
Intra	ZFP64	Q9NTW7	TRIM41	Homo sapiens	Q8WV44	Y2H Prey Pooling	25416956
Intra	ZFP64	Q9NTW7	TRIM41	Homo sapiens	Q8WV44	Y2H Array	25416956
Intra	ZFP64	Q9NTW7	LMO2	Homo sapiens	P25791	Y2H Array	25416956
Intra	ZFP64	Q9NTW7	LNX1	Homo sapiens	Q8TBB1	Y2H Array	29892012
Intra	ZFP64	Q9NTW7	LNX1	Homo sapiens	Q8TBB1	Validated Y2H	25416956
Intra	ZFP64	Q9NTW7	LNX1	Homo sapiens	Q8TBB1	Y2H Prey Pooling	25416956
Intra	ZFP64	Q9NTW7	FAM124A	Homo sapiens	Q86V42	Y2H Prey Pooling	25416956
Intra	ZFP64	Q9NTW7	AEN	Homo sapiens	Q8WTP8	Validated Y2H	25416956
Intra	ZFP64	Q9NTW7	AEN	Homo sapiens	Q8WTP8	Y2H	21516116
Intra	ZFP64	Q9NTW7	AEN	Homo sapiens	Q8WTP8	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16045	ZFP64 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ZFP64	VGNC	VGNC:37167
Felis catus	ZFP64	VGNC	VGNC:81264
Macaca mulatta	ZFP64	VGNC	VGNC:78994
Canis familiaris	ZFP64	VGNC	VGNC:48616
Rattus norvegicus	ZFP64	RGD	RGD:1307948
Mus musculus	ZFP64	MGD	MGI:107342

Name
Email *

	Sorry, but the email address you supplied was invalid.