Med20 - mediator complex subunit 20 Gene

Mus musculus

Also known as Trfp; 1110011O05Rik; 2410115I17Rik

Gene ID: 56771 | Gene type: protein coding

About Med20

Summary

Predicted to enable transcription coactivator activity. Predicted to contribute to ubiquitin protein Ligase activity. Acts upstream of or within skeletal muscle cell differentiation. Part of mediator complex. Is expressed in several structures, including early conceptus; eye; limb mesenchyme; and oocyte. Orthologous to human MED20 (mediator complex subunit 20). [provided by Alliance of Genome Resources, Apr 2022]

Med20 Products(3)

mRNA	Protein	Name
NM_001364926.1	NP_001351855.1	mediator of RNA polymerase II transcription subunit 20 isoform 2
NM_001364927.1	NP_001351856.1	mediator of RNA polymerase II transcription subunit 20 isoform 3
NM_020048.4	NP_064432.1	mediator of RNA polymerase II transcription subunit 20 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12584197	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within skeletal muscle cell differentiation	IMP IMP: Inferred from mutant phenotype	22147266	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of mediator complex	IDA IDA: Inferred from direct assay	15340084	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mediator of RNA polymerase II transcription subunit 20

Trf (TATA binding protein-related factor)-proximal protein homolog

ubiquitin specific protease 49

Med20 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Med20	Q9R0X0	Med30	Mus musculus	Q9CQI9	Anti Tag CoIP	24882805
Cross	Med20	Q9R0X0	MED27	Homo sapiens	Q6P2C8	Anti Tag CoIP	24882805
Cross	Med20	Q9R0X0	MED18	Homo sapiens	Q9BUE0	Anti Tag CoIP	24882805
Cross	Med20	Q9R0X0	MED18	Homo sapiens	Q9BUE0	Anti Tag CoIP	12584197
Cross	Med20	Q9R0X0	MED18	Homo sapiens	Q9BUE0	Biochemical	12584197
Cross	Med20	Q9R0X0	MED18	Homo sapiens	Q9BUE0	Pull Down	12584197
Cross	Med20	Q9R0X0	MED29	Homo sapiens	Q9NX70	Anti Tag CoIP	24882805

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08291	MED20 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Med20	NCBI	NCBI:9477

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