2. Gene
  3. CIAPIN1 - cytokine induced apoptosis inhibitor 1 Gene

CIAPIN1 - cytokine induced apoptosis inhibitor 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DRE2; CIAE2; PRO0915; Anamorsin

Gene ID: 57019 | Gene type: protein coding

About CIAPIN1

Cytogenetic location: 16q21 Genomic coordinates (GRCh38): 16:57,428,187-57,447,385 (from NCBI)

This gene has 15 transcripts (splice variants) and 222 orthologues. Broad expression in testis (RPKM 38.4), placenta (RPKM 14.2) and 24 other tissues.

Summary

CIAPIN1 is a cytokine-induced inhibitor of Apoptosis with no relation to Apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).[supplied by OMIM, Mar 2008]

CIAPIN1 Products(3)

mRNA Protein Name
NM_001308347.2 NP_001295276.1 anamorsin isoform 2
NM_001308358.2 NP_001295287.1 anamorsin isoform 3
NM_020313.4 NP_064709.2 anamorsin isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables 2 iron, 2 sulfur cluster binding IDA
IDA: Inferred from direct assay
27519415 GOA
enables iron ion binding EXP
EXP: Inferred from Experiment
21700214 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16957168 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
16957168 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CIAPIN1 Protein Structure

CIAPIN1

CIAPIN1: Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis (222 - 303)

  • 0
  • 100
  • 200
  • 312 a.a.
Protein Preferred Names Protein Names

anamorsin

fe-S cluster assembly protein DRE2 homolog

Related Diseases

Diseases Alias
Wolfram Syndrome 2

WFS2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02704 CIAPIN1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CIAPIN1 RGD RGD:1549737
Canis familiaris CIAPIN1 VGNC VGNC:39264
Felis catus CIAPIN1 VGNC VGNC:103729
Macaca mulatta CIAPIN1 VGNC VGNC:71117
Bos taurus CIAPIN1 VGNC VGNC:27357
Mus musculus CIAPIN1 MGD MGI:1922083