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  3. RPL13 - ribosomal protein L13 Gene

RPL13 - ribosomal protein L13 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as L13; BBC1; D16S44E; SEMDIST; D16S444E

Gene ID: 6137 | Gene type: protein coding

About RPL13

Cytogenetic location: 16q24.3 Genomic coordinates (GRCh38): 16:89,560,657-89,566,829 (from NCBI)

This gene has 15 transcripts (splice variants), 244 orthologues and is associated with 2 phenotypes. Ubiquitous expression in ovary (RPKM 234.6), spleen (RPKM 109.8) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L13E family of ribosomal proteins. It is located in the cytoplasm. This gene is expressed at significantly higher levels in benign breast lesions than in breast carcinomas. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2011]

RPL13 Products(3)

mRNA Protein Name
NM_000977.4 NP_000968.2 60S ribosomal protein L13 isoform 1
NM_001243131.1 NP_001230060.1 60S ribosomal protein L13 isoform 3
NM_033251.2 NP_150254.1 60S ribosomal protein L13 isoform 1

RPL13 Protein Structure

Ribosomal_L13e

Ribosomal_L13e: Ribosomal protein L13e (8 - 185)

  • 0
  • 100
  • 211 a.a.
Protein Preferred Names Protein Names

60S ribosomal protein L13

breast basic conserved 1

RPL13 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra RPL13 P26373 BRIX1 Homo sapiens Q8TDN6
Anti Tag CoIP
33961781
Intra RPL13 P26373 NCK1 Homo sapiens P16333
Peptide Array
17474147
Intra RPL13 P26373 HTT Homo sapiens P42858
Validated Y2H
32814053
Intra RPL13 P26373 HTT Homo sapiens P42858
Y2H Pooling
32814053
Intra RPL13 P26373 HTT Homo sapiens P42858
Y2H Array
32814053
Intra RPL13 P26373 TERF2 Homo sapiens Q15554
Pull Down
21044950
Intra RPL13 P26373 TERF2 Homo sapiens Q15554
BiFC
21044950
Intra RPL13 P26373 MRPL38 Homo sapiens Q96DV4
Anti Tag CoIP
28514442
Intra RPL13 P26373 PIK3R1 Homo sapiens P27986
Peptide Array
17474147
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spondyloepimetaphyseal Dysplasia, Isidor-Toutain Type

SEMDIST
Spondyloepimetaphyseal Dysplasia

Dysplasia, Spondyloepimetaphyseal
Myeloid And Lymphoid Neoplasms Associated With Fgfr1 Abnormalities
Postcholecystectomy Syndrome

Post Cholecystectomy Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12164 RPL13 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS12165 RPL13A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RPL13 VGNC VGNC:34109
Rattus norvegicus RPL13 RGD RGD:621179
Canis familiaris RPL13 VGNC VGNC:53438
Felis catus RPL13 VGNC VGNC:103746
Macaca mulatta RPL13 VGNC VGNC:82227
Mus musculus RPL13 MGD MGI:105922