KDR - kinase insert domain receptor Gene

Macaca mulatta

Also known as FLK-1

Gene ID: 698293 | Gene type: protein coding

About KDR

Primary_assembly 5: 78,510,576-78,557,981 forward strand.Mmul_10:CM014340.1

This gene has 1 transcript (splice variant), 199 orthologues and 53 paralogues.

KDR Products(1)

mRNA	Protein	Name
XM_015138690.2	XP_014994176.1	vascular endothelial growth factor receptor 2

KDR Protein Structure

IgI_VEGFR

IgI_VEGFR-2

PHA02785

I-set

VEGFR-2_TMD

PTKc_VEGFR2

0
300
600
900
1200
1356 a.a.

Protein Preferred Names

Protein Names

vascular endothelial growth factor receptor 2

kinase insert domain receptor (a type III receptor tyrosine kinase)

Recombinant KDR Proteins

Cat. No.	Product Name	Accession	Purity
HY-P78697	VEGFR-2 Protein, Rhesus macaque (HEK293, His)	F7E313 (A20-E764)	≥95%

Related Agents

Approval

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10260	Vandetanib		99.95%	Yes
HY-112306	Ripretinib		98.90%	Yes
HY-14914	Azilsartan		99.51%	Unkown
HY-10330	Toceranib	Inhibitor	96.86%	Unkown
HY-10330A	Toceranib phosphate	Inhibitor	98.54%	Unkown
HY-10260B	Vandetanib hydrochloride		/	Unkown
HY-10260A	Vandetanib trifluoroacetate		/	Unkown

Clinical Phase

Bioactive Molecules (16)

Cat. No.	Product Name	Effect	Purity	Phase
HY-50751	Linifanib		99.28%	Phase 3
HY-10205	Cediranib		99.58%	Phase 3
HY-13314	Tesevatinib	Inhibitor	99.21%	Phase 3
HY-12018	Vatalanib dihydrochloride		99.91%	Phase 3
HY-13049	Cediranib maleate		99.95%	Phase 3
HY-10203	Vatalanib	Inhibitor	99.93%	Phase 3
HY-12018A	Vatalanib hydrochloride	Inhibitor	/	Phase 3
HY-50751G	Linifanib (GMP)	Inhibitor	/	Phase 3
HY-110272	Vatalanib succinate	Inhibitor	/	Phase 3
HY-10374	Semaxinib	Inhibitor	99.96%	Phase 2
HY-13024	Rebastinib		99.91%	Phase 2
HY-10338	Foretinib	Inhibitor	99.06%	Phase 2
HY-10987A	ENMD-2076		99.12%	Phase 2
HY-10987	ENMD-2076 Tartrate		99.42%	Phase 2
HY-10204	OSI-930		98.57%	Phase 1
HY-100315	XL 999	Inhibitor	99.34%	Phase 1

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99830	Conbercept		/	Phase 4
HY-P99768	Olinvacimab	Inhibitor	95.00%	Phase 2

Pre-clinical Phase

Bioactive Molecules (37)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12299	WH-4-023	Inhibitor	99.75%	Unkown
HY-151361	AMPK-IN-3	Inhibitor	98.51%	Unkown
HY-W062835	CGP77675	Inhibitor	99.00%	Unkown
HY-13561	AZM475271	Inhibitor	99.85%	Unkown
HY-13838	PLX647	Inhibitor	99.79%	Unkown
HY-133551	WF-47-JS03	Inhibitor	99.63%	Unkown
HY-101219	VEGFR-IN-1	Inhibitor	98.42%	Unkown
HY-132135	(1E)-CFI-400437 dihydrochloride	Inhibitor	98.08%	Unkown
HY-15769	WHI-P180	Inhibitor	99.62%	Unkown
HY-18302	c-Kit-IN-5-1	Inhibitor	98.16%	Unkown
HY-125741	GW768505A free base	Inhibitor	98.66%	Unkown
HY-10517A	(Z)-Orantinib	Inhibitor	99.44%	Unkown
HY-13785	ZM 306416	Inhibitor	99.80%	Unkown
HY-119757	Tyrphostin AG1433	Inhibitor	99.08%	Unkown
HY-15814	HG-7-85-01		99.94%	Unkown
HY-100824	PP2 Analog	Inhibitor	/	Unkown
HY-10260S	Vandetanib-d6		/	Unkown
HY-10260S1	Vandetanib-d4		/	Unkown
HY-10260S2	Vandetanib-13C6		/	Unkown
HY-120214	TAS05567	Inhibitor	/	Unkown
HY-13838A	PLX647 dihydrochloride	Inhibitor	/	Unkown
HY-14979	ML786	Inhibitor	/	Unkown
HY-14979A	ML786 dihydrochloride	Inhibitor	/	Unkown
HY-15334	CEP-5214	Inhibitor	/	Unkown
HY-168114	Multi-kinase inhibitor 3	Inhibitor	/	Unkown
HY-168115	Multi-kinase inhibitor 4	Inhibitor	/	Unkown
HY-18318	Takeda-6D	Inhibitor	/	Unkown
HY-RS07226	KDR Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS07227	Kdr Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS07228	Kdr Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W062835A	CGP77675 hydrate	Inhibitor	/	Unkown
HY-10330S	Toceranib-d8	Inhibitor	/	Unkown
HY-110045	ZM-306416 hydrochloride	Inhibitor	/	Unkown
HY-119757A	Tyrphostin AG1433 hydrochloride	Inhibitor	/	Unkown
HY-149451	SYHA1815	Inhibitor	/	Unkown
HY-15769A	WHI-P180 hydrochloride	Inhibitor	/	Unkown
HY-101628	VEGFR-2-IN-9	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	KDR	NCBI	NCBI:3791
Macaca fascicularis	KDR	NCBI	NCBI:102136227
Rattus norvegicus	KDR	NCBI	NCBI:25589

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