CLIP4 - CAP-Gly domain containing linker protein family member 4 Gene

Homo sapiens

Also known as RSNL2

Gene ID: 79745 | Gene type: protein coding

About CLIP4

This gene has 45 transcripts (splice variants), 205 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 10.8), skin (RPKM 7.6) and 23 other tissues.

Summary

Predicted to enable microtubule plus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

CLIP4 Products(4)

mRNA	Protein	Name
NM_001287527.2	NP_001274456.1	CAP-Gly domain-containing linker protein 4 isoform 1
NM_001287528.2	NP_001274457.1	CAP-Gly domain-containing linker protein 4 isoform 2
NM_001410747.1	NP_001397676.1	CAP-Gly domain-containing linker protein 4 isoform 3
NM_024692.6	NP_078968.3	CAP-Gly domain-containing linker protein 4 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLIP4 Protein Structure

Ank_2

CAP_GLY

0
200
400
600
705 a.a.

Protein Preferred Names

Protein Names

CAP-Gly domain-containing linker protein 4

CAP-GLY domain containing linker protein family, member 4

CLIP4 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CLIP4	Q8N3C7	ZNF114	Homo sapiens	Q8NC26	Y2H Array	31515488
Intra	CLIP4	Q8N3C7	ZNF114	Homo sapiens	Q8NC26	Validated Y2H	25416956
Intra	CLIP4	Q8N3C7	ZNF114	Homo sapiens	Q8NC26	Y2H Prey Pooling	32296183
Intra	CLIP4	Q8N3C7	ZNF114	Homo sapiens	Q8NC26	Y2H Prey Pooling	25416956
Intra	CLIP4	Q8N3C7	ZNF114	Homo sapiens	Q8NC26	Validated Y2H	32296183
Intra	CLIP4	Q8N3C7	ZNF114	Homo sapiens	Q8NC26	Y2H Array	32296183
Intra	CLIP4	Q8N3C7	SIX2	Homo sapiens	Q9NPC8	Validated Y2H	32296183
Intra	CLIP4	Q8N3C7	SIX2	Homo sapiens	Q9NPC8	Y2H Array	32296183
Intra	CLIP4	Q8N3C7	SIX2	Homo sapiens	Q9NPC8	Y2H Prey Pooling	32296183
Intra	CLIP4	Q8N3C7	KIFC3	Homo sapiens	Q9BVG8-5	Validated Y2H	32296183
Intra	CLIP4	Q8N3C7	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Array	32296183
Intra	CLIP4	Q8N3C7	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Prey Pooling	32296183
Intra	CLIP4	Q8N3C7	MEOX2	Homo sapiens	Q6FHY5	Y2H Prey Pooling	32296183
Intra	CLIP4	Q8N3C7	MEOX2	Homo sapiens	Q6FHY5	Y2H Array	32296183
Intra	CLIP4	Q8N3C7	KIFC3	Homo sapiens	Q9BVG8	Y2H Array	25416956
Intra	CLIP4	Q8N3C7	KIFC3	Homo sapiens	Q9BVG8	Validated Y2H	25416956
Intra	CLIP4	Q8N3C7	MAP7	Homo sapiens	Q14244	Y2H Array	32296183
Intra	CLIP4	Q8N3C7	MAP7	Homo sapiens	Q14244	Y2H Prey Pooling	32296183
Cross	CLIP4	Q8N3C7	P0DTD1-PRO_0000449630	SARS-CoV-2	P0DTD1-PRO_0000449630	Y2H Array	36217030
Intra	CLIP4	Q8N3C7	TRIP13	Homo sapiens	Q15645	Y2H Prey Pooling	32296183
Intra	CLIP4	Q8N3C7	TRIP13	Homo sapiens	Q15645	Y2H Array	32296183
Intra	CLIP4	Q8N3C7	HSF2BP	Homo sapiens	O75031	Y2H Array	32296183
Intra	CLIP4	Q8N3C7	HSF2BP	Homo sapiens	O75031	Y2H Prey Pooling	32296183
Intra	CLIP4	Q8N3C7	LZTS2	Homo sapiens	Q9BRK4	Y2H Prey Pooling	25416956
Intra	CLIP4	Q8N3C7	TRIM32	Homo sapiens	Q13049	Y2H Array	32296183
Intra	CLIP4	Q8N3C7	TRIM32	Homo sapiens	Q13049	Y2H Prey Pooling	25416956
Intra	CLIP4	Q8N3C7	TRIM32	Homo sapiens	Q13049	Validated Y2H	25416956
Intra	CLIP4	Q8N3C7	TRIM32	Homo sapiens	Q13049	Y2H Prey Pooling	32296183
Intra	CLIP4	Q8N3C7	MAGEA12	Homo sapiens	P43365	Y2H Array	32296183
Intra	CLIP4	Q8N3C7	MAGEA12	Homo sapiens	P43365	Y2H Prey Pooling	32296183
Intra	CLIP4	Q8N3C7	JAKMIP2	Homo sapiens	Q96AA8	MAPPIT	25416956
Intra	CLIP4	Q8N3C7	JAKMIP2	Homo sapiens	Q96AA8	Validated Y2H	25416956
Intra	CLIP4	Q8N3C7	JAKMIP2	Homo sapiens	Q96AA8	Validated Y2H	32296183
Intra	CLIP4	Q8N3C7	JAKMIP2	Homo sapiens	Q96AA8	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02813	CLIP4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CLIP4	RGD	RGD:1311049
Felis catus	CLIP4	VGNC	VGNC:80067
Canis familiaris	CLIP4	VGNC	VGNC:39345
Mus musculus	CLIP4	MGD	MGI:1919100
Macaca mulatta	CLIP4	VGNC	VGNC:81372
Bos taurus	CLIP4	VGNC	VGNC:27447
Others	CLIP4	NCBI

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