2. Gene
  3. LZTS2 - leucine zipper tumor suppressor 2 Gene

LZTS2 - leucine zipper tumor suppressor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as LAPSER1

Gene ID: 84445 | Gene type: protein coding

About LZTS2

Cytogenetic location: 10q24.31 Genomic coordinates (GRCh38): 10:100,996,588-101,007,833 (from NCBI)

This gene has 7 transcripts (splice variants), 268 orthologues and 2 paralogues. Ubiquitous expression in endometrium (RPKM 12.4), fat (RPKM 11.4) and 25 other tissues.

Summary

The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in Cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]

LZTS2 Products(13)

mRNA Protein Name
NM_001318099.2 NP_001305028.1 leucine zipper putative tumor suppressor 2 isoform a
NM_001318100.2 NP_001305029.1 leucine zipper putative tumor suppressor 2 isoform a
NM_001318101.2 NP_001305030.1 leucine zipper putative tumor suppressor 2 isoform b
NM_001394944.1 NP_001381873.1 leucine zipper putative tumor suppressor 2 isoform b
NM_001394945.1 NP_001381874.1 leucine zipper putative tumor suppressor 2 isoform b
NM_001394946.1 NP_001381875.1 leucine zipper putative tumor suppressor 2 isoform b
NM_001394947.1 NP_001381876.1 leucine zipper putative tumor suppressor 2 isoform b
NM_001394948.1 NP_001381877.1 leucine zipper putative tumor suppressor 2 isoform b
NM_001394949.1 NP_001381878.1 leucine zipper putative tumor suppressor 2 isoform b
NM_001394950.1 NP_001381879.1 leucine zipper putative tumor suppressor 2 isoform a
NM_001394951.1 NP_001381880.1 leucine zipper putative tumor suppressor 2 isoform a
NM_001394952.1 NP_001381881.1 leucine zipper putative tumor suppressor 2 isoform a
NM_032429.4 NP_115805.1 leucine zipper putative tumor suppressor 2 isoform a
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Cellular Component GO Annotation Evidence Reference Source
located in vesicle IDA
IDA: Inferred from direct assay
25468996 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LZTS2 Protein Structure

Fez1

Fez1: Fez1 (439 - 637)

  • 0
  • 200
  • 400
  • 600
  • 669 a.a.
Protein Preferred Names Protein Names

leucine zipper putative tumor suppressor 2

leucine zipper, putative tumor suppressor 2

LZTS2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra LZTS2 Q9BRK4 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 ZNF572 Homo sapiens Q7Z3I7
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 a8k932_human Homo sapiens A8K932
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 a8k932_human Homo sapiens A8K932
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZNF250 Homo sapiens P15622-3
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 CEP57L1 Homo sapiens Q8IYX8-2
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 CEP57L1 Homo sapiens Q8IYX8-2
Y2H Array
25416956
Intra LZTS2 Q9BRK4 ZGPAT Homo sapiens Q8N5A5-2
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 FAM107A Homo sapiens O95990-3
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 QARS1 Homo sapiens P47897-2
Y2H Array
25416956
Intra LZTS2 Q9BRK4 QARS1 Homo sapiens P47897-2
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 SLC15A3 Homo sapiens Q05CH4
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SLC15A3 Homo sapiens Q05CH4
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 SH3RF2 Homo sapiens Q08AM8
Y2H Array
25416956
Intra LZTS2 Q9BRK4 UTP14C Homo sapiens Q08E77
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 PLEKHN1 Homo sapiens Q494U1
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 PLEKHN1 Homo sapiens Q494U1
Y2H Array
25416956
Intra LZTS2 Q9BRK4 PLEKHN1 Homo sapiens Q494U1
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 FBF1 Homo sapiens Q8TES7-6
Y2H Array
25416956
Intra LZTS2 Q9BRK4 FAM74A4 Homo sapiens Q5TZK3
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 FAM74A4 Homo sapiens Q5TZK3
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SFRS2 Homo sapiens Q6NXQ0
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 MAB21L3 Homo sapiens Q8N8X9
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 MAB21L3 Homo sapiens Q8N8X9
Y2H Array
25416956
Intra LZTS2 Q9BRK4 CNNM3 Homo sapiens Q8NE01-3
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 CNNM3 Homo sapiens Q8NE01-3
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 STAC Homo sapiens Q8WUK8
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 STAC Homo sapiens Q8WUK8
Y2H Array
25416956
Intra LZTS2 Q9BRK4 POLDIP3 Homo sapiens Q8WUT1
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 POLDIP3 Homo sapiens Q8WUT1
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 POLDIP3 Homo sapiens Q8WUT1
Y2H Array
25416956
Intra LZTS2 Q9BRK4 MORF4L1 Homo sapiens Q9UBU8-2
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 q9h6f0_human Homo sapiens Q9H6F0
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 q9h6f0_human Homo sapiens Q9H6F0
Y2H Array
25416956
Intra LZTS2 Q9BRK4 CABP5 Homo sapiens Q9NP86
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 SHFL Homo sapiens Q9NUL5
Y2H Array
25416956
Intra LZTS2 Q9BRK4 PRKAB2 Homo sapiens O43741
Y2H Array
25416956
Intra LZTS2 Q9BRK4 DYRK1A Homo sapiens Q13627
Anti Tag CoIP
33961781
Intra LZTS2 Q9BRK4 DYRK1A Homo sapiens Q13627
Anti Tag CoIP
23602568
Intra LZTS2 Q9BRK4 POLR1C Homo sapiens O15160
Y2H Array
25416956
Intra LZTS2 Q9BRK4 POLR1C Homo sapiens O15160
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 RAD51D Homo sapiens O75771
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 RAD51D Homo sapiens O75771
Y2H Array
25416956
Intra LZTS2 Q9BRK4 USF2 Homo sapiens Q15853
Y2H Array
25416956
Intra LZTS2 Q9BRK4 PATZ1 Homo sapiens Q9HBE1-4
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 MEMO1 Homo sapiens Q9Y316
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ZNF490 Homo sapiens Q9ULM2
Y2H Array
25416956
Intra LZTS2 Q9BRK4 ABI2 Homo sapiens Q9NYB9-2
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 ATPAF2 Homo sapiens Q8N5M1
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 LCK Homo sapiens P06239
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 LCK Homo sapiens P06239
Y2H Array
25416956
Intra LZTS2 Q9BRK4 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 ZKSCAN3 Homo sapiens Q9BRR0
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZKSCAN3 Homo sapiens Q9BRR0
Y2H Array
25416956
Intra LZTS2 Q9BRK4 KIFC3 Homo sapiens Q9BVG8
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 KIFC3 Homo sapiens Q9BVG8
Y2H Array
25416956
Intra LZTS2 Q9BRK4 HOMER2 Homo sapiens Q9NSB8
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 HOMER2 Homo sapiens Q9NSB8
Y2H Array
25416956
Intra LZTS2 Q9BRK4 HOMER2 Homo sapiens Q9NSB8
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 RNF41 Homo sapiens Q9H4P4
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 RNF41 Homo sapiens Q9H4P4
Y2H Array
25416956
Intra LZTS2 Q9BRK4 EHHADH Homo sapiens Q08426
Y2H Array
25416956
Intra LZTS2 Q9BRK4 FANCL Homo sapiens Q9NW38
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 FANCL Homo sapiens Q9NW38
Y2H Array
25416956
Intra LZTS2 Q9BRK4 TNIP3 Homo sapiens Q96KP6
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 TNIP3 Homo sapiens Q96KP6
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 TNIP3 Homo sapiens Q96KP6
Y2H Array
25416956
Intra LZTS2 Q9BRK4 RBM15 Homo sapiens Q96T37
Y2H Array
25416956
Intra LZTS2 Q9BRK4 FRG1 Homo sapiens Q14331
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 FEM1C Homo sapiens Q96JP0
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 FEM1C Homo sapiens Q96JP0
Y2H Array
25416956
Intra LZTS2 Q9BRK4 FEM1C Homo sapiens Q96JP0
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZMAT2 Homo sapiens Q96NC0
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ZMAT2 Homo sapiens Q96NC0
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SUPV3L1 Homo sapiens Q8IYB8
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 NEBL Homo sapiens O76041
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 EGFR Homo sapiens P00533
Anti Tag CoIP
27956147
Intra LZTS2 Q9BRK4 EGFR Homo sapiens P00533
Ub Reconstruction
27956147
Intra LZTS2 Q9BRK4 ARHGAP32 Homo sapiens A7KAX9
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 TBC1D7 Homo sapiens Q9P0N9
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 TBC1D7 Homo sapiens Q9P0N9
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZGPAT Homo sapiens Q8N5A5
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ZGPAT Homo sapiens Q8N5A5
Y2H Array
25416956
Intra LZTS2 Q9BRK4 QARS1 Homo sapiens P47897
Y2H Array
25416956
Intra LZTS2 Q9BRK4 ZNF408 Homo sapiens Q9H9D4
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 KPNA2 Homo sapiens P52292
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 KPNA2 Homo sapiens P52292
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 SUV39H1 Homo sapiens O43463
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 HSPD1 Homo sapiens P10809
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 HSPD1 Homo sapiens P10809
Y2H
21516116
Intra LZTS2 Q9BRK4 EIF3D Homo sapiens O15371
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SLC25A6 Homo sapiens P12236
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 SLC25A6 Homo sapiens P12236
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 BYSL Homo sapiens Q13895
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 BYSL Homo sapiens Q13895
Y2H Array
25416956
Intra LZTS2 Q9BRK4 PSMA1 Homo sapiens P25786
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 PSMA1 Homo sapiens P25786
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 RIN1 Homo sapiens Q13671
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 EXOSC5 Homo sapiens Q9NQT4
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 SPATC1L Homo sapiens Q9H0A9
Y2H Array
25416956
Intra LZTS2 Q9BRK4 CCNG1 Homo sapiens P51959
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 SPATA24 Homo sapiens Q86W54
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SPATA24 Homo sapiens Q86W54
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 CDKL3 Homo sapiens Q8IVW4
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 CDKL3 Homo sapiens Q8IVW4
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 CCNC Homo sapiens P24863
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 CCNC Homo sapiens P24863
Y2H Array
25416956
Intra LZTS2 Q9BRK4 CDC23 Homo sapiens Q9UJX2
Y2H Array
25416956
Intra LZTS2 Q9BRK4 EIF4E2 Homo sapiens O60573
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 EIF4E2 Homo sapiens O60573
Y2H Array
25416956
Intra LZTS2 Q9BRK4 KAT5 Homo sapiens Q92993
Y2H Array
25416956
Intra LZTS2 Q9BRK4 KAT5 Homo sapiens Q92993
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 MORF4L1 Homo sapiens Q9UBU8
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 GRB2 Homo sapiens P62993
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 GRB2 Homo sapiens P62993
Y2H Array
25416956
Intra LZTS2 Q9BRK4 RAC1 Homo sapiens P63000
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 RAC1 Homo sapiens P63000
Y2H Array
25416956
Intra LZTS2 Q9BRK4 TRIM42 Homo sapiens Q8IWZ5
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 TRIM42 Homo sapiens Q8IWZ5
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 AP1M1 Homo sapiens Q9BXS5
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 CLIP4 Homo sapiens Q8N3C7
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 CLIP4 Homo sapiens Q8N3C7
Y2H Array
25416956
Intra LZTS2 Q9BRK4 GPATCH2L Homo sapiens Q9NWQ4
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 GPATCH2L Homo sapiens Q9NWQ4
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SNW1 Homo sapiens Q13573
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 SNW1 Homo sapiens Q13573
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 DYRK1B Homo sapiens Q9Y463
Anti Tag CoIP
33961781
Intra LZTS2 Q9BRK4 DYRK1B Homo sapiens Q9Y463
BiFC
23602568
Intra LZTS2 Q9BRK4 ICAM5 Homo sapiens Q9UMF0
Validated Y2H
32814053
Intra LZTS2 Q9BRK4 ICAM5 Homo sapiens Q9UMF0
Y2H Pooling
32814053
Intra LZTS2 Q9BRK4 ICAM5 Homo sapiens Q9UMF0
Y2H Array
32814053
Intra LZTS2 Q9BRK4 FGF12 Homo sapiens P61328
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 TRIM29 Homo sapiens Q14134
Y2H Array
25416956
Intra LZTS2 Q9BRK4 TCEA2 Homo sapiens Q15560
Y2H Array
25416956
Intra LZTS2 Q9BRK4 CBX8 Homo sapiens Q9HC52
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 CBX8 Homo sapiens Q9HC52
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 CBX8 Homo sapiens Q9HC52
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 NCK2 Homo sapiens O43639
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 NCK2 Homo sapiens O43639
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 PQBP1 Homo sapiens O60828
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 MTA1 Homo sapiens Q13330
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 MTA1 Homo sapiens Q13330
Y2H Array
25416956
Intra LZTS2 Q9BRK4 C8orf33 Homo sapiens Q9H7E9
Y2H Array
25416956
Intra LZTS2 Q9BRK4 C8orf33 Homo sapiens Q9H7E9
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 INO80B Homo sapiens Q9C086
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 SPG7 Homo sapiens Q9UQ90
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 SPG7 Homo sapiens Q9UQ90
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZNF20 Homo sapiens P17024
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ZNF20 Homo sapiens P17024
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZNF20 Homo sapiens P17024
Y2H Array
25416956
Intra LZTS2 Q9BRK4 FAM161A Homo sapiens Q3B820
Y2H Array
25416956
Intra LZTS2 Q9BRK4 PKP4 Homo sapiens Q99569
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 PKP4 Homo sapiens Q99569
Y2H Array
25416956
Intra LZTS2 Q9BRK4 LMO2 Homo sapiens P25791
Y2H Array
25416956
Intra LZTS2 Q9BRK4 CCNK Homo sapiens O75909
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 CCNK Homo sapiens O75909
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZBTB25 Homo sapiens P24278
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ZBTB25 Homo sapiens P24278
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZBTB25 Homo sapiens P24278
Y2H Array
25416956
Intra LZTS2 Q9BRK4 DCUN1D1 Homo sapiens Q96GG9
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 DCUN1D1 Homo sapiens Q96GG9
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ZNF446 Homo sapiens Q9NWS9-2
Y2H Array
25416956
Intra LZTS2 Q9BRK4 NEK6 Homo sapiens Q9HC98
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 NEK6 Homo sapiens Q9HC98
Y2H Array
25416956
Intra LZTS2 Q9BRK4 ZNF417 Homo sapiens Q8TAU3
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZNF417 Homo sapiens Q8TAU3
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ZNF417 Homo sapiens Q8TAU3
Y2H Array
25416956
Intra LZTS2 Q9BRK4 RBM41 Homo sapiens Q96IZ5
Y2H Array
25416956
Intra LZTS2 Q9BRK4 TCHP Homo sapiens Q9BT92
Y2H Array
25416956
Intra LZTS2 Q9BRK4 CNNM3 Homo sapiens Q8NE01
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 CNNM3 Homo sapiens Q8NE01
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 NTAQ1 Homo sapiens Q96HA8
Y2H Array
25416956
Intra LZTS2 Q9BRK4 NTAQ1 Homo sapiens Q96HA8
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 THAP7 Homo sapiens Q9BT49
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 CHIC2 Homo sapiens Q9UKJ5
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 FAM124B Homo sapiens Q9H5Z6
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 FAM124B Homo sapiens Q9H5Z6
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SMIM3 Homo sapiens Q9BZL3
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 BAHD1 Homo sapiens Q8TBE0
Y2H Array
25416956
Intra LZTS2 Q9BRK4 FAM50B Homo sapiens Q9Y247
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 LASP1 Homo sapiens Q14847
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 LASP1 Homo sapiens Q14847
Y2H Array
25416956
Intra LZTS2 Q9BRK4 ARMC7 Homo sapiens Q9H6L4
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ARMC7 Homo sapiens Q9H6L4
Y2H Array
25416956
Intra LZTS2 Q9BRK4 DGCR6L Homo sapiens Q9BY27
Y2H Array
25416956
Intra LZTS2 Q9BRK4 ZNF426 Homo sapiens Q9BUY5
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZNF426 Homo sapiens Q9BUY5
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ZNF426 Homo sapiens Q9BUY5
Y2H Array
25416956
Intra LZTS2 Q9BRK4 CHCHD3 Homo sapiens Q9NX63
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 RCOR3 Homo sapiens Q9P2K3
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 RCOR3 Homo sapiens Q9P2K3
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 RCOR3 Homo sapiens Q9P2K3
Y2H Array
25416956
Intra LZTS2 Q9BRK4 RAMAC Homo sapiens Q9BTL3
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 RAMAC Homo sapiens Q9BTL3
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SPATA2 Homo sapiens Q9UM82
Y2H Array
25416956
Intra LZTS2 Q9BRK4 GEM Homo sapiens P55040
Y2H Array
25416956
Intra LZTS2 Q9BRK4 GEM Homo sapiens P55040
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 GEM Homo sapiens P55040
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 MYOZ1 Homo sapiens Q9NP98
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 FKBP6 Homo sapiens O75344
Y2H Array
31515488
Intra LZTS2 Q9BRK4 FKBP6 Homo sapiens O75344
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 FKBP6 Homo sapiens O75344
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ANKRD36BP1 Homo sapiens Q96IX9
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ANKRD36BP1 Homo sapiens Q96IX9
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SYT17 Homo sapiens Q9BSW7
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 THAP10 Homo sapiens Q9P2Z0
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 THAP10 Homo sapiens Q9P2Z0
Y2H Array
25416956
Intra LZTS2 Q9BRK4 ZNF581 Homo sapiens Q9P0T4
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 GMCL2 Homo sapiens Q8NEA9
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 GMCL2 Homo sapiens Q8NEA9
Y2H Array
25416956
Intra LZTS2 Q9BRK4 GMCL2 Homo sapiens Q8NEA9
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 IQCN Homo sapiens Q9H0B3
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 CDK18 Homo sapiens Q07002
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 GCC1 Homo sapiens Q96CN9
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 GCC1 Homo sapiens Q96CN9
Y2H Array
25416956
Intra LZTS2 Q9BRK4 OTUB2 Homo sapiens Q96DC9
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 TXNL4A Homo sapiens P83876
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 TXNL4A Homo sapiens P83876
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 ZMYND19 Homo sapiens Q96E35
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 ZMYND19 Homo sapiens Q96E35
Y2H
21516116
Intra LZTS2 Q9BRK4 ZMYND19 Homo sapiens Q96E35
Y2H Array
25416956
Intra LZTS2 Q9BRK4 ZMYND19 Homo sapiens Q96E35
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 GNL3L Homo sapiens Q9NVN8
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 GNL3L Homo sapiens Q9NVN8
Y2H Array
25416956
Intra LZTS2 Q9BRK4 GNL3L Homo sapiens Q9NVN8
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 SH2D4A Homo sapiens Q9H788
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 SH2D4A Homo sapiens Q9H788
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SCNM1 Homo sapiens Q9BWG6
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 SCNM1 Homo sapiens Q9BWG6
Y2H Array
25416956
Intra LZTS2 Q9BRK4 NIP7 Homo sapiens Q9Y221
Y2H Array
25416956
Intra LZTS2 Q9BRK4 NIP7 Homo sapiens Q9Y221
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 CFAP206 Homo sapiens Q8IYR0
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 CFAP206 Homo sapiens Q8IYR0
Y2H Array
25416956
Intra LZTS2 Q9BRK4 DYRK2 Homo sapiens Q92630
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 SLU7 Homo sapiens O95391
Y2H Array
25416956
Intra LZTS2 Q9BRK4 SLU7 Homo sapiens O95391
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 CARD9 Homo sapiens Q9H257
Y2H Array
25416956
Intra LZTS2 Q9BRK4 CARD9 Homo sapiens Q9H257
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 MAGEB4 Homo sapiens O15481
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 LMO1 Homo sapiens P25800
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 LMO1 Homo sapiens P25800
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 AIRIM Homo sapiens Q9NX04
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 AIRIM Homo sapiens Q9NX04
Validated Y2H
32296183
Intra LZTS2 Q9BRK4 SNX31 Homo sapiens Q8N9S9
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 KAZN Homo sapiens Q674X7
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 KAZN Homo sapiens Q674X7
Y2H Array
25416956
Intra LZTS2 Q9BRK4 RHNO1 Homo sapiens Q9BSD3
Y2H Prey Pooling
25416956
Intra LZTS2 Q9BRK4 RHNO1 Homo sapiens Q9BSD3
Y2H Array
25416956
Intra LZTS2 Q9BRK4 RHNO1 Homo sapiens Q9BSD3
Validated Y2H
25416956
Intra LZTS2 Q9BRK4 MORN3 Homo sapiens Q6PF18
Y2H Array
25416956
Intra LZTS2 Q9BRK4 MORN3 Homo sapiens Q6PF18
Y2H Prey Pooling
25416956
Cross LZTS2 Q9BRK4 tax Human T-cell leukemia virus P03410
Y2H Pooling
22458338
Cross LZTS2 Q9BRK4 rex_htl1c Human T-cell leukemia virus 1 P0C206
Y2H Array
22458338
Cross LZTS2 Q9BRK4 rex_htl1c Human T-cell leukemia virus 1 P0C206
Y2H Pooling
22458338
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07935 LZTS2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus LZTS2 VGNC VGNC:63353
Mus musculus LZTS2 MGD MGI:2385095
Canis familiaris LZTS2 VGNC VGNC:52997
Bos taurus LZTS2 VGNC VGNC:31122
Rattus norvegicus LZTS2 RGD RGD:1359249
Macaca mulatta LZTS2 VGNC VGNC:74393