Dgkz - diacylglycerol kinase zeta Gene

Rattus norvegicus

Gene ID: 81821 | Gene type: protein coding

About Dgkz

Summary

Enables diacylglycerol kinase activity. Predicted to be involved in several processes, including glycerolipid metabolic process; lipid phosphorylation; and maintenance of postsynaptic density structure. Predicted to act upstream of or within negative regulation of Ras protein signal transduction. Located in nucleus. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human DGKZ (diacylglycerol kinase zeta). [provided by Alliance of Genome Resources, Apr 2022]

Dgkz Products(1)

mRNA	Protein	Name
NM_031143.2	NP_112405.1	diacylglycerol kinase zeta

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables ATP-dependent diacylglycerol kinase activity	IDA IDA: Inferred from direct assay	8855332	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	15157668	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	19229292	RGD
is active in postsynaptic density	IDA IDA: Inferred from direct assay	19229292	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

diacylglycerol kinase zeta

104 kDa diacylglycerol kinase	DAG kinase zeta
DGK-IV	DGK-zeta
diglyceride kinase zeta

Dgkz Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Dgkz	O08560	Dlg3	Rattus norvegicus	Q62936	Anti Tag CoIP	19229292
Intra	Dgkz	O08560	Dlg3	Rattus norvegicus	Q62936	Anti Bait CoIP	19229292
Intra	Dgkz	O08560	Dlg4	Rattus norvegicus	P31016	Anti Bait CoIP	19229292
Intra	Dgkz	O08560	Dlg4	Rattus norvegicus	P31016	Y2H	19229292
Intra	Dgkz	O08560	Dlg1	Rattus norvegicus	Q62696	Y2H	19229292
Intra	Dgkz	O08560	Dlg1	Rattus norvegicus	Q62696	Anti Tag CoIP	19229292
Intra	Dgkz	O08560	Dlg1	Rattus norvegicus	Q62696	Anti Bait CoIP	19229292
Intra	Dgkz	O08560	Dlg2	Rattus norvegicus	Q63622	Anti Tag CoIP	19229292
Intra	Dgkz	O08560	Dlg2	Rattus norvegicus	Q63622	Anti Bait CoIP	19229292

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03724	DGKZ Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dgkz	NCBI	NCBI:8525

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