SCAMP1 - secretory carrier membrane protein 1 Gene

Homo sapiens

Also known as SCAMP; SCAMP37

Gene ID: 9522 | Gene type: protein coding

About SCAMP1

Cytogenetic location: 5q14.1 Genomic coordinates (GRCh38): 5:78,360,617-78,480,739 (from NCBI)

This gene has 7 transcripts (splice variants), 259 orthologues and 4 paralogues. Ubiquitous expression in brain (RPKM 21.2), thyroid (RPKM 14.8) and 25 other tissues.

Summary

This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

SCAMP1 Products(2)

mRNA	Protein	Name
NM_001290229.2	NP_001277158.1	secretory carrier-associated membrane protein 1 isoform 3
NM_004866.6	NP_004857.4	secretory carrier-associated membrane protein 1 isoform 1

SCAMP1 Protein Structure

SCAMP

0
100
200
300
338 a.a.

Protein Preferred Names

Protein Names

secretory carrier-associated membrane protein 1

SCAMP1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SCAMP1	O15126	TTPA	Homo sapiens	P49638	Validated Y2H	32296183
Intra	SCAMP1	O15126	NDRG4	Homo sapiens	Q9ULP0-2	Validated Y2H	32296183
Intra	SCAMP1	O15126	PCYT1A	Homo sapiens	P49585	Validated Y2H	32296183
Intra	SCAMP1	O15126	ARFIP1	Homo sapiens	P53367	Validated Y2H	32296183
Intra	SCAMP1	O15126	DNAJC13	Homo sapiens	O75165	Anti Tag CoIP	33961781
Intra	SCAMP1	O15126	DNAJC13	Homo sapiens	O75165	Anti Tag CoIP	28514442
Intra	SCAMP1	O15126	ARFIP2	Homo sapiens	P53365	Validated Y2H	32296183
Intra	SCAMP1	O15126	TBRG4	Homo sapiens	Q969Z0	Validated Y2H	32296183
Intra	SCAMP1	O15126	THAP4	Homo sapiens	Q8WY91	Validated Y2H	32296183
Intra	SCAMP1	O15126	PBX3	Homo sapiens	Q96AL5	Validated Y2H	32296183
Intra	SCAMP1	O15126	SPG21	Homo sapiens	Q9NZD8	Validated Y2H	32296183
Intra	SCAMP1	O15126	PTPN9	Homo sapiens	P43378	Validated Y2H	32296183
Intra	SCAMP1	O15126	MTERF3	Homo sapiens	Q96E29	Validated Y2H	32296183
Intra	SCAMP1	O15126	GAD2	Homo sapiens	Q05329	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Childhood Kidney Cell Carcinoma

Pediatric Renal Cell Carcinoma

Childhood Renal Cell Carcinoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12478	SCAMP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SCAMP1	MGD	MGI:1349480
Macaca mulatta	SCAMP1	VGNC	VGNC:84489
Bos taurus	SCAMP1	VGNC	VGNC:34315
Canis familiaris	SCAMP1	VGNC	VGNC:45890
Felis catus	SCAMP1	VGNC	VGNC:64895
Rattus norvegicus	SCAMP1	RGD	RGD:3625

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