CDC20 - cell division cycle 20 Gene

Homo sapiens

Also known as CDC20A; p55CDC; bA276H19.3

Gene ID: 991 | Gene type: protein coding

About CDC20

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:43,358,981-43,363,203 (from NCBI)

This gene has 4 transcripts (splice variants), 220 orthologues and 2 paralogues. Biased expression in testis (RPKM 26.5), bone marrow (RPKM 19.7) and 12 other tissues.

Summary

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]

CDC20 Products(1)

mRNA	Protein	Name
NM_001255.3	NP_001246.2	cell division cycle protein 20 homolog

CDC20 Protein Structure

WD40

0
100
200
300
400
499 a.a.

Protein Preferred Names

Protein Names

cell division cycle protein 20 homolog

CDC20 cell division cycle 20 homolog

Related Diseases

Diseases

Alias

Mosaic Variegated Aneuploidy Syndrome 1

Mva Syndrome	MVA1
Mosaic Variegated Aneuploidy Syndrome, Type 1	Mosaic Variegated Aneuploidy Syndrome
Congenital Chromosomal Disease

Mosaic Variegated Aneuploidy Syndrome

Warburton-Anyane-Yeboa Syndrome	Mva Syndrome
Mosaic Variegated Aneuplody Microcephaly Syndrome	Warburton Anyane Yeboa Syndrome

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (12)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-110287	Apcin	Inhibitor	99.71%	Unkown
HY-130257	CP5V	Inhibitor	99.31%	Unkown
HY-100341	M2I-1	Inhibitor	≥98.0%	Unkown
HY-130841	Apcin-A	Inhibitor	≥98.0%	Unkown
HY-116006	Bis-PEG5-acid		95.77%	Unkown
HY-13255	TAME	Inhibitor	99.51%	Unkown
HY-131959	(S,R,S)-AHPC-PEG5-Boc		95.29%	Unkown
HY-13255A	TAME hydrochloride	Inhibitor	98.31%	Unkown
HY-161257	CDC20-IN-1	Inducer	/	Unkown
HY-RS02288	CDC20 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS02289	CDC20B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W614725	Apcin-A monohydrochloride	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CDC20	VGNC	VGNC:107502
Rattus norvegicus	CDC20	RGD	RGD:620477
Mus musculus	CDC20	MGD	MGI:1859866
Bos taurus	CDC20	VGNC	VGNC:27060
Canis familiaris	CDC20	VGNC	VGNC:38987

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