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  5. Hexadecanamide

Hexadecanamide  (Synonyms: Palmitamide)

Cat. No.: HY-121389 Purity: ≥97.0%
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Hexadecanamide (Palmitamide), a fatty acid amide, has orally active anti-allergic, antioxidant, and neuroprotective effects. Hexadecanamide alleviate S. aureus-caused mastitis by depressing inflammatory response and maintaining blood-milk barrier integrity. Hexadecanamide depresses S. aureus-induced activation of the NF-κB pathway in mouse mammary epithelial cells (MMECs). Hexadecanamide activates PPARα. Hexadecanamide enhances sperm motility in vitro.

For research use only. We do not sell to patients.

Hexadecanamide Chemical Structure

Hexadecanamide Chemical Structure

CAS No. : 629-54-9

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Based on 1 publication(s) in Google Scholar

Hexadecanamide Related Antibodies

Top Publications Citing Use of Products

View All NF-κB Isoform Specific Products:

View All Isoforms
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

View All PPAR Isoform Specific Products:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

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Description

Hexadecanamide (Palmitamide), a fatty acid amide, has orally active anti-allergic, antioxidant, and neuroprotective effects. Hexadecanamide alleviate S. aureus-caused mastitis by depressing inflammatory response and maintaining blood-milk barrier integrity. Hexadecanamide depresses S. aureus-induced activation of the NF-κB pathway in mouse mammary epithelial cells (MMECs). Hexadecanamide activates PPARα. Hexadecanamide enhances sperm motility in vitro[1][2].

IC50 & Target

PPARα

 

Molecular Weight

255.44

Formula

C16H33NO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC(CCCCCCCCCCCCCCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (19.57 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9148 mL 19.5741 mL 39.1481 mL
5 mM 0.7830 mL 3.9148 mL 7.8296 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

COA (238 KB) HNMR (232 KB) MS (80 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9148 mL 19.5741 mL 39.1481 mL 97.8703 mL
5 mM 0.7830 mL 3.9148 mL 7.8296 mL 19.5741 mL
10 mM 0.3915 mL 1.9574 mL 3.9148 mL 9.7870 mL
15 mM 0.2610 mL 1.3049 mL 2.6099 mL 6.5247 mL
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Hexadecanamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hexadecanamide629-54-9PalmitamideBacterialNF-κBPPARNuclear factor-κBNuclear factor-kappaBPeroxisome proliferator-activated receptorsanti-allergicantioxidantand neuroprotectiveInhibitorinhibitorinhibit

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