2. Cell Cycle/DNA Damage Apoptosis
  3. G-quadruplex Apoptosis
  4. L5-DA

L5-DA is a G-quadruplex (G4) ligand and selectively stabilized for G4s over ds26. L5-DA exhibits significant cytotoxicity against HeLa cells (IC50=4.3 μM). L5-DA stabilizes G4s in HeLa cells, induces apoptosis, and cell cycle arrest.

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L5-DA Chemical Structure

L5-DA Chemical Structure

CAS No. : 2986876-41-7

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Based on 1 publication(s) in Google Scholar

L5-DA Related Antibodies

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Description

L5-DA is a G-quadruplex (G4) ligand and selectively stabilized for G4s over ds26. L5-DA exhibits significant cytotoxicity against HeLa cells (IC50=4.3 μM). L5-DA stabilizes G4s in HeLa cells, induces apoptosis, and cell cycle arrest[1].

Molecular Weight

534.65

Formula

C32H34N6O2
CAS No.
SMILES

CN(CCOC1=CC2=C(N(C=C2)C3=CC=C4C=CC(N5C=CC6=C5C=CC(OCCN(C)C)=C6)=NC4=N3)C=C1)C
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Purity & Documentation
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L5-DA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L5-DA2986876-41-7G-quadruplexApoptosisG-quadruplexesligandHeLa cellscell cycle arrestcytotoxicityInhibitorinhibitorinhibit

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