2. Apoptosis Metabolic Enzyme/Protease Immunology/Inflammation
  3. Apoptosis Arginase
  4. nor-NOHA dihydrochloride

nor-NOHA dihydrochloride  (Synonyms: Nω-Hydroxy-nor-L-arginine dihydrochloride)

Cat. No.: HY-112885C Purity: 98.85%
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nor-NOHA dihydrochloride is a selective and reversible arginase inhibitor. nor-NOHA dihydrochloride induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride can used in study endothelial dysfunction, immunosuppression and metabolism.

For research use only. We do not sell to patients.

nor-NOHA dihydrochloride Chemical Structure

nor-NOHA dihydrochloride Chemical Structure

CAS No. : 291758-32-2

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5 mg USD 155 In-stock
10 mg USD 250 In-stock
25 mg USD 490 In-stock
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Based on 2 publication(s) in Google Scholar

Other Forms of nor-NOHA dihydrochloride:

nor-NOHA dihydrochloride Related Antibodies

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Description

nor-NOHA dihydrochloride is a selective and reversible arginase inhibitor. nor-NOHA dihydrochloride induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride can used in study endothelial dysfunction, immunosuppression and metabolism[1].

Molecular Weight

249.10

Formula

C5H14Cl2N4O3
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

OC([C@@H](N)CCNC(NO)=N)=O.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (401.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0145 mL 20.0723 mL 40.1445 mL
5 mM 0.8029 mL 4.0145 mL 8.0289 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0145 mL 20.0723 mL 40.1445 mL 100.3613 mL
5 mM 0.8029 mL 4.0145 mL 8.0289 mL 20.0723 mL
10 mM 0.4014 mL 2.0072 mL 4.0145 mL 10.0361 mL
15 mM 0.2676 mL 1.3382 mL 2.6763 mL 6.6908 mL
20 mM 0.2007 mL 1.0036 mL 2.0072 mL 5.0181 mL
25 mM 0.1606 mL 0.8029 mL 1.6058 mL 4.0145 mL
30 mM 0.1338 mL 0.6691 mL 1.3382 mL 3.3454 mL
40 mM 0.1004 mL 0.5018 mL 1.0036 mL 2.5090 mL
50 mM 0.0803 mL 0.4014 mL 0.8029 mL 2.0072 mL
60 mM 0.0669 mL 0.3345 mL 0.6691 mL 1.6727 mL
80 mM 0.0502 mL 0.2509 mL 0.5018 mL 1.2545 mL
100 mM 0.0401 mL 0.2007 mL 0.4014 mL 1.0036 mL
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nor-NOHA dihydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

nor-NOHA291758-32-2Nω-Hydroxy-nor-L-arginineApoptosisArginaseArginase InhibitorARG2Anti-leukemicImunosuppressionEdothelial dysfunctionInhibitorinhibitorinhibit

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