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  5. Phenylalanylalanine

Phenylalanylalanine  (Synonyms: H-Phe-Ala-OH)

Cat. No.: HY-W009602 Purity: 99.47%
SDS COA Handling Instructions

Molarity Calculator

Phenylalanylalanine (H-Phe-Ala-OH) is a dipeptide composed of phenylalanine and alanine. Phenylalanylalanine is an incomplete breakdown product of protein digestion or protein catabolism.

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Phenylalanylalanine Chemical Structure

Phenylalanylalanine Chemical Structure

CAS No. : 3918-87-4

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Based on 1 publication(s) in Google Scholar

Phenylalanylalanine Related Antibodies

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Description

Phenylalanylalanine (H-Phe-Ala-OH) is a dipeptide composed of phenylalanine and alanine. Phenylalanylalanine is an incomplete breakdown product of protein digestion or protein catabolism[1].

Cellular Effect
Cell Line Type Value Description References
Caco-2 IC50
0.18 μM
Compound: phe-ala
Concentration required to inhibit the maximum [14C]Gly-Sar uptake by human Intestinal peptide transporter PepT1 in Caco-2 cells
Concentration required to inhibit the maximum [14C]Gly-Sar uptake by human Intestinal peptide transporter PepT1 in Caco-2 cells
[PMID: 14761208]
Molecular Weight

236.27

Formula

C12H16N2O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)N)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (423.24 mM; Need ultrasonic)

DMSO : 4.35 mg/mL (18.41 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2324 mL 21.1622 mL 42.3245 mL
5 mM 0.8465 mL 4.2324 mL 8.4649 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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Animal weight
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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.47%

SDS (393 KB)

COA (245 KB) HNMR (125 KB) RP-HPLC (266 KB) OR (228 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.2324 mL 21.1622 mL 42.3245 mL 105.8111 mL
5 mM 0.8465 mL 4.2324 mL 8.4649 mL 21.1622 mL
10 mM 0.4232 mL 2.1162 mL 4.2324 mL 10.5811 mL
15 mM 0.2822 mL 1.4108 mL 2.8216 mL 7.0541 mL
H2O 20 mM 0.2116 mL 1.0581 mL 2.1162 mL 5.2906 mL
25 mM 0.1693 mL 0.8465 mL 1.6930 mL 4.2324 mL
30 mM 0.1411 mL 0.7054 mL 1.4108 mL 3.5270 mL
40 mM 0.1058 mL 0.5291 mL 1.0581 mL 2.6453 mL
50 mM 0.0846 mL 0.4232 mL 0.8465 mL 2.1162 mL
60 mM 0.0705 mL 0.3527 mL 0.7054 mL 1.7635 mL
80 mM 0.0529 mL 0.2645 mL 0.5291 mL 1.3226 mL
100 mM 0.0423 mL 0.2116 mL 0.4232 mL 1.0581 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Phenylalanylalanine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenylalanylalanine3918-87-4H-Phe-Ala-OHOthersInhibitorinhibitorinhibit

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