1. PI3K/Akt/mTOR
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  3. PI3K-IN-36

PI3K-IN-36 (compound A36) is a potent PI3K inhibitor. PI3K-IN-36 can be used in research of follicular lymphoma (FL).

For research use only. We do not sell to patients.

PI3K-IN-36 Chemical Structure

PI3K-IN-36 Chemical Structure

CAS No. : 1401436-93-8

Size Price Stock Quantity
1 mg USD 204 In-stock
5 mg USD 510 In-stock
10 mg USD 820 In-stock
25 mg USD 1680 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

PI3K-IN-36 (compound A36) is a potent PI3K inhibitor. PI3K-IN-36 can be used in research of follicular lymphoma (FL)[1].

Molecular Weight

562.66

Formula

C30H36F2N8O

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

FC(C1=NC2=C(N1C3=NC(NC(C)(CC4=C(C5CCNCC5)C=CC=C4)C)=NC(N6CCOCC6)=N3)C=CC=C2)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (22.22 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7773 mL 8.8864 mL 17.7727 mL
5 mM 0.3555 mL 1.7773 mL 3.5545 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7773 mL 8.8864 mL 17.7727 mL 44.4318 mL
5 mM 0.3555 mL 1.7773 mL 3.5545 mL 8.8864 mL
10 mM 0.1777 mL 0.8886 mL 1.7773 mL 4.4432 mL
15 mM 0.1185 mL 0.5924 mL 1.1848 mL 2.9621 mL
20 mM 0.0889 mL 0.4443 mL 0.8886 mL 2.2216 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PI3K-IN-36
Cat. No.:
HY-150019
Quantity:
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