2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-33

IL-33

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Cat. No. Product Name / Synonyms Species Source
  • HY-P7218
    IL-33 Protein, Mouse

    rMuIL-33; Il33

    		Mouse E. coli
    IL-33 Protein, Mouse is a tissue-derived nuclear cytokine from the IL-1 family abundantly expressed in endothelial cells, epithelial cells and fibroblast-like cells, both during homeostasis and inflammation.
  • HY-P7041
    IL-33 Protein, Human

    rHuIL-33; IL-1F11; NF-HEV; DVS 27

    		Human E. coli
    IL-33 Protein, Human, a Th2 cytokine, is a specific ligand for ST2L.
  • HY-P700208AF
    Animal-Free IL-33 Protein, Mouse (His)

    Interleukin-33; IL-33; Interleukin-1 FamILy Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV

    		Mouse E. coli
    IL-33 protein activates NF-kappa-B and MAPK signaling, inducing Th2 cell maturation and cytokine secretion. It activates mast cells, basophils, eosinophils, and natural killer cells and enhances macrophage polarization. Animal-Free IL-33 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-33 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-33 Protein, Mouse (His) is 158 a.a., with molecular weight of ~18.51 kDa.
  • HY-P70475
    IL-33 Protein, Human (His)

    Interleukin-33; IL-33; Interleukin-1 Family Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV

    		Human E. coli
    IL-33 protein, as a cytokine, binds to and signals through the IL1RL1/ST2 receptor, thereby activating the NF-kappa-B and MAPK signaling pathways in target cells. It is involved in the maturation of Th2 cells and contributes to the secretion of T helper cell type 2 related cytokines. IL-33 Protein, Human (His) is the recombinant human-derived IL-33 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P73210
    IL-33 Protein, Canine

    Interleukin-33; IL-33; IL-1F11; NF-HEV; DVS 27

    		Canine E. coli
    IL-33 Protein activates NF-kappa-B and MAPK signaling, inducing Th2 cell maturation and cytokine secretion. It activates mast cells, basophils, eosinophils, and natural killer cells, acting as a chemoattractant for Th2 cells. IL-33 preserves Krebs cycle integrity, reducing reactive oxygen species production. In quiescent endothelial cells, IL-33 acts as a transcriptional repressor, but is lost upon angiogenic or pro-inflammatory activation. IL-33 Protein, Canine is the recombinant canine-derived IL-33 protein, expressed by E. coli , with N-Met labeled tag. The total length of IL-33 Protein, Canine is 154 a.a., with molecular weight of ~19 kDa.
  • HY-P70475AF
    Animal-Free IL-33 Protein, Human (His)

    Interleukin-33; IL-33; Interleukin-1 Family Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV

    		Human E. coli
    IL-33 protein, as a cytokine, binds to and signals through the IL1RL1/ST2 receptor, thereby activating the NF-kappa-B and MAPK signaling pathways in target cells. It is involved in the maturation of Th2 cells and contributes to the secretion of T helper cell type 2 related cytokines. Animal-Free IL-33 Protein, Human (His) is the recombinant human-derived animal-FreeIL-33 protein, expressed by E. coli , with C-His labeled tag.
  • HY-P72548
    IL-33 Protein, Rhesus macaque (His)

    Interleukin-33; IL-33; IL-1F11; NF-HEV; IL33; C9orf26

    		Rhesus Macaque E. coli
    IL-33 is a member of the IL-1 family, known for its significant divergence. IL-33 Protein, Rhesus macaque (His) is the recombinant Rhesus Macaque-derived IL-33 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IL-33 Protein, Rhesus macaque (His) is 159 a.a., with molecular weight of ~21 kDa.
  • HY-P73883
    IL-33 Protein, Cynomolgus

    Interleukin-33; IL-33; IL-1F11; NF-HEV; DVS 27

    		Cynomolgus E. coli
    IL-33 Protein is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 acts intracellularly as a nuclear factor and extracellularly as a cytokine. IL-33 mediates its biological effects via IL-1 receptor ST 2, activates NF-kappaB and MAP kinases, and drives production of T(H)2-associated cytokines from in vitro polarized T(H)2 cells. IL-33 Protein, Cynomolgus is the recombinant cynomolgus-derived IL-33 protein, expressed by E. coli , with tag free.
  • HY-P77966
    IL-33 Protein, Cynomolgus (HEK293, His)

    C9orf26 Z; DVS27; IL1F11; NF-HEV; NFEHEV; IL33; DV27; C9ORF26; RP11-575C20.2

    		Cynomolgus HEK293
    IL-33 Protein, part of the IL-1 family, is a divergent cytokine pivotal in immune responses and inflammation. Operating through its receptor ST2, IL-33 promotes activation and recruitment of immune cells like Th2 cells, mast cells, and eosinophils to inflammation sites. Produced by epithelial and endothelial cells, IL-33 induces pro-inflammatory cytokines and chemokines. Implicated in asthma, allergic diseases, and autoimmune disorders, IL-33 emerges as a therapeutic target for immune response modulation. IL-33 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-33 protein, expressed by HEK293, with N-His labeled tag. The total length of IL-33 Protein, Cynomolgus (HEK293, His) is 162 a.a., with molecular weight of 25-30 kDa.
Cat. No. Product Name Effect Purity