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Results for "

Acne

" in MedChemExpress (MCE) Product Catalog:

63

Inhibitors & Agonists

2

Peptides

11

Natural
Products

12

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106947
    SY-640

    		Endogenous Metabolite Metabolic Disease
    SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice .
    SY-640
  • HY-15127
    Isotretinoin
    Maximum Cited Publications
    8 Publications Verification

    13-cis-Retinoic acid

    		 RAR/RXR Endogenous Metabolite Autophagy Cancer
    Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity .
    Isotretinoin
  • HY-13858A
    Sarecycline hydrochloride
    4 Publications Verification

    P-005672 hydrochloride

    		 Antibiotic Bacterial DNA/RNA Synthesis Infection
    Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline hydrochloride can be used to study moderate to severe acne .
    Sarecycline hydrochloride
  • HY-Y0366
    Lauric acid
    3 Publications Verification

    		 Endogenous Metabolite Bacterial Infection
    Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively .
    Lauric acid
  • HY-126386A
    Pectinase, aspergillus acne

    		Biochemical Assay Reagents Others
    Pectinase, aspergillus acne is a mixed enzymes that hydrolyze pectic substances, it mostly presents in microorganisms and higher plants. Pectinase is involved in the metabolism of the cell wall as well as in the growth of the cell, senescence, ripening of fruits, pathogenesis and abscission process .
    Pectinase, aspergillus acne
  • HY-123156
    SC-23110

    		Bacterial Infection
    SC-23110 is a potent anti-acne agent. SC-23110 inhibits the growth of P. acnes, one of the organisms associated with acne, and most frequently mentioned as the organism involved in the pathogenesis of inflammatory pustules/lesions .
    SC-23110
  • HY-133949
    8,11-Eicosadiynoic acid

    		5 alpha Reductase Endocrinology
    8,11-Eicosadiynoic acid, an unsaturated fatty acid, is a steroid 5α-reductase inhibitor. 8,11-Eicosadiynoic acid can be used for the research of acne .
    8,11-Eicosadiynoic acid
  • HY-161976
    ACC1-IN-2

    		Acetyl-CoA Carboxylase Inflammation/Immunology
    ACC1-IN-2 (Compound 16) is an ACC1 inhibitor with an IC50 of 7.3 nM. ACC1-IN-2 can be used in the study of acne .
    ACC1-IN-2
  • HY-16770
    Sarecycline

    P-005672

    		 Antibiotic Bacterial DNA/RNA Synthesis Infection
    Sarecycline is an orally effective narrow-spectrum tetracycline derivative antibiotic. Sarecycline has anti-inflammatory activity. Sarecycline inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline can be used to study moderate to severe acne .
    Sarecycline
  • HY-13858AR
    Sarecycline (hydrochloride) (Standard)

    		Antibiotic Bacterial DNA/RNA Synthesis Infection
    Sarecycline (hydrochloride) (Standard) is the analytical standard of Sarecycline (hydrochloride). This product is intended for research and analytical applications. Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline hydrochloride can be used to study moderate to severe acne .
    Sarecycline (hydrochloride) (Standard)
  • HY-15127R
    Isotretinoin (Standard)

    		RAR/RXR Endogenous Metabolite Autophagy Cancer
    Isotretinoin (Standard) is the analytical standard of Isotretinoin. This product is intended for research and analytical applications. Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity .
    Isotretinoin (Standard)
  • HY-139077
    SCD1 inhibitor-3

    		Stearoyl-CoA Desaturase (SCD) Metabolic Disease Cancer
    SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II diabetes and dyslipidemia, as well as skin diseases, acne and cancer .
    SCD1 inhibitor-3
  • HY-122941
    Viscidulin II

    		Interleukin Related Inflammation/Immunology
    Viscidulin II (FL6) is a flavone. Viscidulin II can be isolated from the root of Scutellaria baicalensis. Viscidulin II significantly suppresses P. acnes-induced IL-8 and IL-1β production in THP-1 cells .
    Viscidulin II
  • HY-107385
    Epristeride
    1 Publications Verification

    ONO-9302; SKF105657

    		 5 alpha Reductase Cancer
    Epristeride (ONO-9302) is a selective, specific and orally active uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. Epristeride has inhibitory effects for SR isoenzymes types 2 with Ki value of 0.7-2 nM. Epristeride can be used for the research of prostatic hyperplasia and acne .
    Epristeride
  • HY-B0091A
    Adapalene sodium salt

    CD 271 sodium salt

    		 RAR/RXR Autophagy Apoptosis Neurological Disease Inflammation/Immunology Cancer
    Adapalene (CD271) sodium salt, a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene sodium salt is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene sodium salt also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene sodium salt exhibits anti-tumor activity .
    Adapalene sodium salt
  • HY-B0091
    Adapalene
    4 Publications Verification

    CD271

    		 RAR/RXR Autophagy Apoptosis Neurological Disease Inflammation/Immunology Cancer
    Adapalene (CD271), a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene exhibits anti-tumor activity .
    Adapalene
  • HY-B1064A
    Clindamycin phosphate hydrochloride

    Clindamycin 2-phosphate hydrochloride; U-28508 hydrochloride

    		 Bacterial Antibiotic Parasite Infection Cancer
    Clindamycin phosphate (Clindamycin 2-phosphate) hydrochloride is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate hydrochloride is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate hydrochloride can be used for researching acne and bacterial vaginosis .
    Clindamycin phosphate hydrochloride
  • HY-107385R
    Epristeride (Standard)

    		5 alpha Reductase Cancer
    Epristeride (Standard) is the analytical standard of Epristeride. This product is intended for research and analytical applications. Epristeride (ONO-9302) is a selective, specific and orally active uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. Epristeride has inhibitory effects for SR isoenzymes types 2 with Ki value of 0.7-2 nM. Epristeride can be used for the research of prostatic hyperplasia and acne .
    Epristeride (Standard)
  • HY-P2170
    XMP-629

    XOMA-629

    		 Antibiotic Bacterial Infection Inflammation/Immunology
    XMP-629 (XOMA-629), a cationic α-helical peptide, is a potent endotoxin inhibitor. XMP-629 exhibits broad-spectrum antimicrobial activity via an immunomodulatory mechanism. XOMA 629 has antimicrobial activity against Propionibacterium acnes, Staphylococcus aureus and Streptococcus pyogenesand .
    XMP-629
  • HY-B1064
    Clindamycin phosphate
    Maximum Cited Publications
    8 Publications Verification

    Clindamycin 2-phosphate; U-28508

    		 Bacterial Antibiotic Parasite Infection Cancer
    Clindamycin phosphate (Clindamycin 2-phosphate) is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate can be used for researching acne and bacterial vaginosis .Clindamycin phosphate has no cytotoxicity。 Combined with platelet rich fibrin (PRF), PRF-Clindamycin phosphate enhances antimicrobial properties .
    Clindamycin phosphate
  • HY-B0483
    Tioxolone

    		Carbonic Anhydrase Metabolic Disease
    Tioxolone is an inhibitor of the metalloenzyme carbonic anhydrase I and has anti-acne activity.
    Tioxolone
  • HY-112077A
    Viaminate

    		RAR/RXR Inflammation/Immunology
    Viaminate is a derivative of Retinoic acid, which is used for the treatment of severe acne and other keratinization disorders.
    Viaminate
  • HY-B0506
    Nadifloxacin
    1 Publications Verification

    OPC7251

    		 Bacterial Antibiotic Infection
    Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris.
    Nadifloxacin
  • HY-B1366
    Meclocycline Sulfosalicylate Salt

    		Bacterial Antibiotic Infection
    Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris .
    Meclocycline Sulfosalicylate Salt
  • HY-121456
    Salnacedin

    G-201

    		 Drug Metabolite Inflammation/Immunology
    Salnacedin (G-201) has anti-inflammatory and keratolytic activity. Salnacedin can be used in the research of seborrhoeic dermatitis and acne .
    Salnacedin
  • HY-14802
    Talarozole (R enantiomer)

    (R)-Talarozole

    		 Cytochrome P450 Cancer
    Talarozole R enantiomer is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid for the treatment of psoriasis and acne.
    Talarozole (R enantiomer)
  • HY-B0483R
    Tioxolone (Standard)

    		Carbonic Anhydrase Metabolic Disease
    Tioxolone (Standard) is the analytical standard of Tioxolone. This product is intended for research and analytical applications. Tioxolone is an inhibitor of the metalloenzyme carbonic anhydrase I and has anti-acne activity.
    Tioxolone (Standard)
  • HY-100256R
    Trifarotene (Standard)

    		RAR/RXR Autophagy Inflammation/Immunology
    Trifarotene (Standard) is the analytical standard of Trifarotene. This product is intended for research and analytical applications. Trifarotene (CD5789) is a potent and selective RARγ agonist. Trifarotene (CD5789) shows ∼65-fold and ∼16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM), respectively .
    Trifarotene (Standard)
  • HY-100256
    Trifarotene

    CD5789

    		 RAR/RXR Autophagy Inflammation/Immunology
    Trifarotene (CD5789) is a potent and selective RARγ agonist. Trifarotene (CD5789) shows ∼65-fold and ∼16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM), respectively .
    Trifarotene
  • HY-112077AR
    Viaminate (Standard)

    		RAR/RXR Inflammation/Immunology
    Viaminate (Standard) is the analytical standard of Viaminate. This product is intended for research and analytical applications. Viaminate is a derivative of Retinoic acid, which is used for the treatment of severe acne and other keratinization disorders.
    Viaminate (Standard)
  • HY-B0506R
    Nadifloxacin (Standard)

    		Bacterial Antibiotic Infection
    Nadifloxacin (Standard) is the analytical standard of Nadifloxacin. This product is intended for research and analytical applications. Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris.
    Nadifloxacin (Standard)
  • HY-B0894
    Resorcinol monoacetate

    Acetylresorcinol; Resorcin monoacetate

    		 Biochemical Assay Reagents Inflammation/Immunology
    Resorcinol monoacetate (Acetylresorcinol) is an antiseptic and a disinfectant, is a chemical intermediate for the production of many other pharmaceuticals, and has the potential for acne, seborrheic dermatitis, eczema, psoriasis, and other skin disorders research.
    Resorcinol monoacetate
  • HY-15388S
    Tazarotene-d8

    AGN 190168-d8

    		 Isotope-Labeled Compounds RAR/RXR Autophagy Inflammation/Immunology Cancer
    Tazarotene-d8 is the deuterium labeled Tazarotene. Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris[1][2].
    Tazarotene-d8
  • HY-17560
    Demeclocycline hydrochloride
    4 Publications Verification

    		 Bacterial Antibiotic Infection Metabolic Disease Inflammation/Immunology Cancer
    Demeclocycline hydrochloride is a tetracycline antibiotic, which is found in a mutant strain of Streptomyces aureofaciens. Demeclocycline hydrochloride is promising for research of Lyme disease, acne, chronic inappropriate antidiuretic hormone secretion and bronchitis .
    Demeclocycline hydrochloride
  • HY-15127S
    Isotretinoin-d5

    		Isotope-Labeled Compounds RAR/RXR Endogenous Metabolite Autophagy Cancer
    Isotretinoin-d5 is the deuterium labeled Isotretinoin. Isotretinoin is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity[1][2][3].
    Isotretinoin-d5
  • HY-B1366R
    Meclocycline (Sulfosalicylate Salt) (Standard)

    		Bacterial Antibiotic Infection
    Meclocycline (Sulfosalicylate Salt) (Standard) is the analytical standard of Meclocycline (Sulfosalicylate Salt). This product is intended for research and analytical applications. Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris .
    Meclocycline (Sulfosalicylate Salt) (Standard)
  • HY-105048
    Omiganan
    1 Publications Verification

    		 Bacterial Antibiotic Infection
    Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne .
    Omiganan
  • HY-Y0366S
    Lauric acid-13C

    		Endogenous Metabolite Bacterial Infection
    Lauric acid- 13C is the 13C labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-13C
  • HY-Y0366S5
    Lauric acid-d5

    		Isotope-Labeled Compounds Endogenous Metabolite Bacterial Infection
    Lauric acid-d5 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-d5
  • HY-Y0366S3
    Lauric acid-d3

    		Isotope-Labeled Compounds Endogenous Metabolite Bacterial Infection
    Lauric acid-d33 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-d3
  • HY-Y0366S2
    Lauric acid-d2

    		Isotope-Labeled Compounds Endogenous Metabolite Bacterial Infection
    Lauric acid-d2 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-d2
  • HY-Y0366S1
    Lauric acid-d23

    		Endogenous Metabolite Bacterial Infection
    Lauric acid-d233 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-d23
  • HY-Y0366R
    Lauric acid (Standard)
    3 Publications Verification

    		 Endogenous Metabolite Bacterial Infection
    Lauric acid (Standard) is the analytical standard of Lauric acid. This product is intended for research and analytical applications. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid (Standard)
  • HY-B0704
    Azelaic acid
    1 Publications Verification

    Nonanedioic acid

    		 Antibiotic Endogenous Metabolite Inflammation/Immunology
    Azelaic acid is a nine-carbon dicarboxylic acid. Azelaic acid has antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis through inhibition of microbial cellular prorein synthesis. Azelaic acid has hypopigmentation action resulting from its ability to scavenge free radicals .
    Azelaic acid
  • HY-15388
    Tazarotene
    2 Publications Verification

    AGN 190168

    		 RAR/RXR Autophagy Inflammation/Immunology Cancer
    Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Tazarotene
  • HY-Y0366S4
    Lauric acid-13C-1

    		Isotope-Labeled Compounds Endogenous Metabolite Bacterial Cardiovascular Disease
    Lauric acid- 13C-1 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively[1].
    Lauric acid-13C-1
  • HY-10979
    AN0128

    		Bacterial Infection Inflammation/Immunology
    AN0128 is a boron-containing antibacterial and anti-inflammatory agent. AN0128 against S. aureus, S. epidermidis, P. acnes, B. subtilis with minimum inhibitory concentration (MIC) values of 1, 0.5, 0.3, 1 μg/mL. AN0128 can be used for the research of periodontal disease and cutaneous diseases .
    AN0128
  • HY-15388R
    Tazarotene (Standard)

    		RAR/RXR Autophagy Inflammation/Immunology Cancer
    Tazarotene (Standard) is the analytical standard of Tazarotene. This product is intended for research and analytical applications. Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Tazarotene (Standard)
  • HY-B0688
    Dapsone
    2 Publications Verification

    4,4′-Diaminodiphenyl sulfone; DDS

    		 Antibiotic Parasite Bacterial Reactive Oxygen Species Infection Inflammation/Immunology
    Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .
    Dapsone
  • HY-B1064R
    Clindamycin phosphate (Standard)

    Clindamycin 2-phosphate (Standard); U-28508 (Standard)

    		 Bacterial Antibiotic Parasite Infection
    Clindamycin phosphate (Standard) is the analytical standard of Clindamycin phosphate. This product is intended for research and analytical applications. Clindamycin phosphate (Clindamycin 2-phosphate) is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate can be used for researching acne and bacterial vaginosis .
    Clindamycin phosphate (Standard)

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