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Aflatoxin inhibitor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Antibiotic (3) Apoptosis (4) Bacterial (4) Calcium Channel (1) DNA/RNA Synthesis (3) Endogenous Metabolite (3) Fungal (5) Interleukin Related (1) Isotope-Labeled Compounds (1) Lipoxygenase (1) MDM-2/p53 (1) Opioid Receptor (1) Parasite (3) RSV (1) TNF Receptor (1) α-synuclein (1)
By Research Areas:	Cancer (3) Infection (12) Inflammation/Immunology (1) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1939

Cyclo(L-Leu-L-Pro) Cyclo(L-prolyl-L-leucyl)	Fungal	Infection
Cyclo(L-Leu-L-Pro) is an inhibitory substance targeting to production of norsolorinic acid (NA，a precursor of aflatoxin)，which can be isolated from A. xylosoxidans NFRI-A1. Cyclo(L-Leu-L-Pro) inhibits accumulation of NA by A. parasiticus NFRI-95 and inhibits spore formation. Cyclo(L-Leu-L-Pro) inhibits aflatoxin production with an IC₅₀ of 0.2 mg/mL in A. parasiticus SYS-4 .

HY-W089845

Heneicosane 1 Publications Verification	Fungal	Infection
Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. Heneicosane is a pheromone and inhibits aflatoxin production .

HY-N6725

Sterigmatocystine	DNA/RNA Synthesis Bacterial Apoptosis Antibiotic Endogenous Metabolite	Infection Cancer
Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor . Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals .

HY-113542

Blasticidin A (+)-Blasticidin A	Bacterial Antibiotic Parasite	Infection
Blasticidin A ((+)-Blasticidin A) is an inhibitor of Aflatoxin production by Aspergillus parasiticus. Blasticidin A almost completely inhibits Aflatoxin production at 0.5 μM . Blasticidin A is a potent antibiotic produced by Streptomyces, inhibits Aflatoxin production without strong growth inhibition toward Aflatoxin-producing fungi .

HY-N12056

Cyclo(L-leucyl-L-valyl)	Fungal	Infection
Cyclo(L-leucyl-L-valyl) inhibits Aflatoxin production by Aspergillus parasiticus.Cyclo(L-leucyl-L-valyl) inhibits transcription of the Aflatoxin-related genes aflR, hexB, pksL1, and dmtA. .

HY-W663938

Cyflumetofen	Parasite	Others
Cyflumetofen is a synthetic miticide that strongly inhibits mitochondrial complex II of spider mites, but not of insects, crustaceans, or mammals. Cyflumetofen is not significantly effective in inhibiting aflatoxin production in fungi .

HY-W663938R

Cyflumetofen (Standard)	Parasite	Others
Cyflumetofen (Standard) is the analytical standard of Cyflumetofen. This product is intended for research and analytical applications. Cyflumetofen is a synthetic miticide that strongly inhibits mitochondrial complex II of spider mites, but not of insects, crustaceans, or mammals. Cyflumetofen is not significantly effective in inhibiting aflatoxin production in fungi .

HY-W089845S

Heneicosane-d44	Fungal	Infection
Heneicosane-d₄₄ is the deuterium labeled Heneicosane[1]. Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. Heneicosane is a pheromone and inhibits aflatoxin production[2][3][4].

HY-W089845R

Heneicosane (Standard)	Fungal	Infection
Heneicosane (Standard) is the analytical standard of Heneicosane. This product is intended for research and analytical applications. Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. Heneicosane is a pheromone and inhibits aflatoxin production .

HY-N6725R

Sterigmatocystine (Standard)	DNA/RNA Synthesis Bacterial Apoptosis Antibiotic Endogenous Metabolite	Infection Cancer
Sterigmatocystine (Standard) is the analytical standard of Sterigmatocystine. This product is intended for research and analytical applications. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor . Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals .

HY-N1952S

Isoeugenol-d3 iso-Eugenol-d₃	Bacterial Isotope-Labeled Compounds	Infection
Isoeugenol-d₃ is deuterated labeled Sterigmatocystine (HY-N6725). Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor . Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals .

HY-N6771

Cyclopiazonic acid 3 Publications Verification	Calcium Channel 5-HT Receptor MDM-2/p53 Apoptosis RSV	Infection
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B ^[1][4][5].

HY-133002

Methyl sterculate Sterculic acid methyl ester; Methyl Sterculate	Others	Infection
Sterculic acid methyl ester is an ester form of sterculic acid, which is an inhibitor of Δ9 desaturase. Sterculic acid methyl ester (0.75 mM) inhibits the growth of, and is toxic to, the bacteria R. opacus. It decreases the fatty acid content, increases the ratio of palmitate to other fatty acids, and decreases the levels of stearate and oleate in R. opacus when used at concentrations of 0.25 or 0.5 mM. Sterculic acid methyl ester (50 ppm) has a synergistic effect on increased tumor growth induced by aflatoxin Q1 in rainbow trout.

HY-Y0790R

Cuminaldehyde (Standard)	Endogenous Metabolite Apoptosis DNA/RNA Synthesis α-synuclein Lipoxygenase Opioid Receptor Interleukin Related TNF Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Cuminaldehyde (Standard) is the analytical standard of Cuminaldehyde. This product is intended for research and analytical applications. Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities, including anti-inflammatory, anti-cancer, anti-diabetic, anti-injury, anti-neuropathy and antibacterial effects. Cuminaldehyde is an inhibitor of aldose reductase (IC₅₀= 0.00085 mg/mL) and α-glucosidase (IC₅₀=0.5 mg/mL). Cuminaldehyde can modulate α-synuclein fibrils. Cuminaldehyde can induce apoptosis in colon adenocarcinoma cells by targeting topoisomerase I and II. In addition, Cuminaldehyde also exerts anti-inflammatory activity by inhibiting lipoxygenase. Cuminaldehyde has a strong inhibitory effect on the growth of Aspergillus flavus and the biosynthesis of aflatoxin B1 (AFB1). Cuminaldehyde can exert anti-injury and anti-neuropathy effects by participating in opioid receptors, L-arginine/NO/cGMP pathways and anti-inflammatory effects. Cuminaldehyde has potential application value in the research of neurodegenerative diseases, cancer, diabetes and neuropathic pain diseases .

Cat. No.	Product Name	Target	Research Area

HY-P1939

Cyclo(L-Leu-L-Pro) Cyclo(L-prolyl-L-leucyl)	Fungal	Infection
Cyclo(L-Leu-L-Pro) is an inhibitory substance targeting to production of norsolorinic acid (NA，a precursor of aflatoxin)，which can be isolated from A. xylosoxidans NFRI-A1. Cyclo(L-Leu-L-Pro) inhibits accumulation of NA by A. parasiticus NFRI-95 and inhibits spore formation. Cyclo(L-Leu-L-Pro) inhibits aflatoxin production with an IC₅₀ of 0.2 mg/mL in A. parasiticus SYS-4 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W089845

Heneicosane 1 Publications Verification	Infection Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	Fungal
Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. Heneicosane is a pheromone and inhibits aflatoxin production .

HY-N6725

Sterigmatocystine	Infection Structural Classification Monophenols Microorganisms Xanthones Classification of Application Fields Source classification Phenols Disease Research Fields	DNA/RNA Synthesis Bacterial Apoptosis Antibiotic Endogenous Metabolite
Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor . Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals .

HY-N6771

Cyclopiazonic acid 3 Publications Verification	Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Disease Research Fields Indole Alkaloids	Calcium Channel 5-HT Receptor MDM-2/p53 Apoptosis RSV
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B ^[1][4][5].

HY-N12056

Cyclo(L-leucyl-L-valyl)	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Fungal
Cyclo(L-leucyl-L-valyl) inhibits Aflatoxin production by Aspergillus parasiticus.Cyclo(L-leucyl-L-valyl) inhibits transcription of the Aflatoxin-related genes aflR, hexB, pksL1, and dmtA. .

HY-W089845R

Heneicosane (Standard)	Structural Classification Natural Products other families Source classification Plants	Fungal
Heneicosane (Standard) is the analytical standard of Heneicosane. This product is intended for research and analytical applications. Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. Heneicosane is a pheromone and inhibits aflatoxin production .

HY-N6725R

Sterigmatocystine (Standard)	Infection Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Disease Research Fields	DNA/RNA Synthesis Bacterial Apoptosis Antibiotic Endogenous Metabolite
Sterigmatocystine (Standard) is the analytical standard of Sterigmatocystine. This product is intended for research and analytical applications. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor . Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals .

HY-Y0790R

Cuminaldehyde (Standard)	Structural Classification Ketones, Aldehydes, Acids Rudbeckia laciniata L. Source classification Umbelliferae Plants Endogenous metabolite	Endogenous Metabolite Apoptosis DNA/RNA Synthesis α-synuclein Lipoxygenase Opioid Receptor Interleukin Related TNF Receptor
Cuminaldehyde (Standard) is the analytical standard of Cuminaldehyde. This product is intended for research and analytical applications. Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities, including anti-inflammatory, anti-cancer, anti-diabetic, anti-injury, anti-neuropathy and antibacterial effects. Cuminaldehyde is an inhibitor of aldose reductase (IC₅₀= 0.00085 mg/mL) and α-glucosidase (IC₅₀=0.5 mg/mL). Cuminaldehyde can modulate α-synuclein fibrils. Cuminaldehyde can induce apoptosis in colon adenocarcinoma cells by targeting topoisomerase I and II. In addition, Cuminaldehyde also exerts anti-inflammatory activity by inhibiting lipoxygenase. Cuminaldehyde has a strong inhibitory effect on the growth of Aspergillus flavus and the biosynthesis of aflatoxin B1 (AFB1). Cuminaldehyde can exert anti-injury and anti-neuropathy effects by participating in opioid receptors, L-arginine/NO/cGMP pathways and anti-inflammatory effects. Cuminaldehyde has potential application value in the research of neurodegenerative diseases, cancer, diabetes and neuropathic pain diseases .

Cat. No.	Product Name	Chemical Structure

HY-W089845S

Heneicosane-d44
Heneicosane-d₄₄ is the deuterium labeled Heneicosane[1]. Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. Heneicosane is a pheromone and inhibits aflatoxin production[2][3][4].

HY-N1952S

Isoeugenol-d3
Isoeugenol-d₃ is deuterated labeled Sterigmatocystine (HY-N6725). Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor . Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals .

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Aflatoxin inhibitor

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products