B7.2

By Targets:	Autophagy (2) Bacterial (2) Carboxylesterase (CES) (2) CD28 (2) Endogenous Metabolite (1) Glucocorticoid Receptor (1) iGluR (1) p38 MAPK (2) UGT (2)
By Research Areas:	Cancer (4) Endocrinology (1) Infection (4) Inflammation/Immunology (5) Metabolic Disease (2) Neurological Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1618

Corticosterone 35+ Cited Publications 17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B	Glucocorticoid Receptor Endogenous Metabolite iGluR	Neurological Disease Inflammation/Immunology Endocrinology
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .

HY-P1698

Reltecimod AB-103	Bacterial CD28	Infection Inflammation/Immunology Cancer
Reltecimod (AB-103) is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod can be used to research necrotizing soft-tissue infections (NSTIs) .

HY-N0235

Bakuchiol 2 Publications Verification (S)-(+)-Bakuchiol	Carboxylesterase (CES) p38 MAPK Autophagy UGT	Infection Metabolic Disease Inflammation/Immunology Cancer
Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC₅₀s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.

HY-P1698B

Reltecimod TFA AB-103 TFA	Bacterial CD28	Infection Inflammation/Immunology Cancer
Reltecimod (AB-103) TFA is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod TFA has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod TFA modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod TFA can be used to research necrotizing soft-tissue infections (NSTIs) .

HY-N0235R

Bakuchiol (Standard)	Carboxylesterase (CES) p38 MAPK Autophagy UGT	Infection Metabolic Disease Inflammation/Immunology Cancer
Bakuchiol (Standard) is the analytical standard of Bakuchiol. This product is intended for research and analytical applications. Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC₅₀s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.

Cat. No.	Product Name	Target	Research Area

HY-P1698

Reltecimod AB-103	Bacterial CD28	Infection Inflammation/Immunology Cancer
Reltecimod (AB-103) is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod can be used to research necrotizing soft-tissue infections (NSTIs) .

HY-P1698B

Reltecimod TFA AB-103 TFA	Bacterial CD28	Infection Inflammation/Immunology Cancer
Reltecimod (AB-103) TFA is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod TFA has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod TFA modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod TFA can be used to research necrotizing soft-tissue infections (NSTIs) .

Cat. No.	Product Name	Target	Research Area

HY-P990260

*Anti-Mouse CD86/B7-2* Antibody (GL-1)**	Inhibitory Antibodies	Others
Anti-Mouse CD86/B7-2 Antibody (GL-1) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD86/B7-2.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1618

Corticosterone 35+ Cited Publications 17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B	Structural Classification Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Glucocorticoid Receptor Endogenous Metabolite iGluR
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .

HY-N0235

Bakuchiol 2 Publications Verification (S)-(+)-Bakuchiol	Structural Classification Monophenols Classification of Application Fields Leguminosae Source classification Phenols Psoralea corylifolia L. Plants Disease Research Fields Cancer	Carboxylesterase (CES) p38 MAPK Autophagy UGT
Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC₅₀s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.

HY-N0235R

Bakuchiol (Standard)	Structural Classification Monophenols Leguminosae Source classification Phenols Psoralea corylifolia L. Plants	Carboxylesterase (CES) p38 MAPK Autophagy UGT
Bakuchiol (Standard) is the analytical standard of Bakuchiol. This product is intended for research and analytical applications. Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC₅₀s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.

Species:	Human (7) Rhesus Macaque (2) Rat (1) Mouse (2) Cynomolgus (2) Rabbit (1)
Tag:	His (9) Avi (4) Fc (4)
Source:	HEK293 (13)

Cat. No.	Compare	Product Name	Species	Source

HY-P72766

	B7-2/CD86 Protein, Rabbit (HEK293, His) T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86	Rabbit	HEK293
	The B7-2/CD86 protein is a key receptor that provides costimulatory signals critical for T lymphocyte proliferation and interleukin-2 production through CD28 or CTLA-4 binding. It plays a decisive role in early T cell activation, affecting immunity or anergy within 24 hours. B7-2/CD86 Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived B7-2/CD86 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of B7-2/CD86 Protein, Rabbit (HEK293, His) is 224 a.a., with molecular weight of 39-67 kDa.

HY-P75489

	B7-2/CD86 Protein, Human (Biotinylated, HEK293, His) Activation B7-2 antigen; B70; BU63; CD86; CD28LG2	Human	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-2/CD86 Protein, Human (Biotinylated, HEK293, His) is 220 a.a., with molecular weight of ~26.2 kDa.

HY-P70795

	B7-2/CD86 Protein, Human (HEK293, His) T-Lymphocyte Activation Antigen CD86; Activation B7-2 Antigen; B70; BU63; CTLA-4 Counter-Receptor B7.2; FUN-1; CD86; CD28LG2	Human	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (HEK293, His) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P78064

	B7-2/CD86 Protein, Human (Biotinylated, HEK293, His-Avi) CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2	Human	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of B7-2/CD86 Protein, Human (Biotinylated, HEK293, His-Avi) is 222 a.a., with molecular weight of 55-70 kDa.

HY-P7636

	B7-2/CD86 Protein, Rat (HEK293, His) rRtB7-2, His; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86	Rat	HEK293
	B7-2/CD86 Protein, Rat (HEK293, His), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation.

HY-P7322

	B7-2/CD86 Protein, Human (HEK293, Fc) rHuB7-2/CD86, Fc Chimera; Activation B7-2 antigen; B70; BU63; CD86; CD28LG2	Human	HEK293
	B7-2/CD86 Protein, Human (HEK293, Fc) is a polypeptide chain with the C-termimal human IgG1 Fc fragment produced in HEK293 cells. B7-2 (CD86) is a costimulatory molecule expressed by antigen-presenting cells (APCs), which interacts with CD28 for T-cell activation and survival and with CTLA4 for immune regulation.

HY-P78383

	B7-2/CD86 Protein, Human (HEK293, His-Avi) CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2	Human	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (HEK293, His-Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of B7-2/CD86 Protein, Human (HEK293, His-Avi) is 222 a.a., with molecular weight of 55-70 kDa.

HY-P703877

	B7-2/CD86 Protein, Human (Biotinylated, HEK293, hFc, Avi) CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2	Human	HEK293

HY-P703878

	B7-2/CD86 Protein, Human (Biotinylated, HEK293, His, Avi) CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2	Human	HEK293

HY-P7835

	B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, hFc) Activation B7-2 antigen; B70; BU63; CD86; CD28LG2	Rhesus Macaque;Cynomolgus	HEK293
	B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, hFc) is the recombinant Rhesus Macaque, cynomolgus-derived B7-2/CD86 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P7637

	B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) rRhB7-2, His; T-lymphocyte activation antigen CD86 isoform 1; Activation B7-2 antigen; CD86	Rhesus Macaque;Cynomolgus	HEK293
	B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, His), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation.

HY-P7638

	B7-2/CD86 Protein, Mouse (HEK293, His) rMuB7-2, His; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1; CD86	Mouse	HEK293
	B7-2/CD86 Protein, Mouse (HEK293, His), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation.

HY-P7635

	B7-2/CD86 Protein, Mouse (HEK293, Fc) rMuB7-2, C-Fc; T-lymphocyte activation antigen CD86; Early T-cell costimulatory molecule 1; ETC-1; CD86	Mouse	HEK293
	B7-2/CD86 Protein, Mouse (HEK293, Fc), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80609

	CD86 Antibody CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86	WB, IHC-P, ICC/IF, IP, FC	Human, Rat
	CD86 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 38 kDa, targeting to CD86. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Rat.

HY-P83710M

	Rat Anti-Mouse CD86 Antibody (FITC) T-lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1	FC	Mouse
	CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Name
Email *

	Sorry, but the email address you supplied was invalid.

B7.2

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Antibodies

Natural
Products