Search Result

Isoforms Recommended:	ErbB2/HER2 EGFR/ErbB1/HER1

Results for "

ERBB2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Amino Acid Derivatives (1) Apoptosis (10) Autophagy (10) Btk (1) CDK (2) EGFR (52) Ephrin Receptor (1) Ferroptosis (9) HSP (2) IKK (1) Isotope-Labeled Compounds (5) Itk (1) JAK (1) Orthopoxvirus (2) Paraptosis (1) PI4K (1) Raf (1) Ras (1) Small Interfering RNA (siRNA) (3) Src (1) Trk Receptor (1) VEGFR (1)
By Research Areas:	Cancer (51) Endocrinology (1) Infection (3) Inflammation/Immunology (4) Neurological Disease (1)
Oligonucleotides:	Aptamers (1) Pre-designed siRNA Sets (3) siRNAs (3)

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P4082

ErbB-2-binding peptide HER2-binding peptide	EGFR	Cancer
ErbB-2-binding peptide (HER2-binding peptide) is a tumor-binding peptide. ErbB-2-binding peptide has the potential for cancer research .

HY-103443

HKI-357	EGFR	Cancer
HKI-357 is an irreversible dual inhibitor of EGFR and *ERBB2* with IC₅₀s of 34 nM and 33 nM, respectively. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation .

HY-103441

JNJ28871063 hydrochloride	EGFR	Cancer
JNJ28871063 hydrochloride is an orally active, highly selective and ATP competitive *pan-ErbB* kinase inhibitor with IC₅₀** values of 22 nM, 38 nM, and 21 nM for ErbB1, ErbB2, and ErbB4, respectively. JNJ28871063 hydrochloride inhibits phosphorylation of functionally important tyrosine residues in both EGFR and ErbB2. JNJ28871063 hydrochloride crosses the blood-brain barrier and has antitumor activity in human tumor xenograft models that overexpress EGFR and ErbB2 .

HY-RS04466

ERBB2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ERBB2 Human Pre-designed siRNA Set A contains three designed siRNAs for ERBB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ERBB2 Human Pre-designed siRNA Set A ERBB2 Human Pre-designed siRNA Set A

HY-RS04467

Erbb2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Erbb2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Erbb2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Erbb2 Mouse Pre-designed siRNA Set A Erbb2 Mouse Pre-designed siRNA Set A

HY-RS04468

ERBB2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ERBB2 Rat Pre-designed siRNA Set A contains three designed siRNAs for ERBB2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

ERBB2 Rat Pre-designed siRNA Set A ERBB2 Rat Pre-designed siRNA Set A

HY-156639

*EGFR/ErbB-2* inhibitor-1**	EGFR	Cancer
EGFR/ErbB-2 inhibitor-1 is a ErbB2/HER2 inhibitor .

HY-P99558

Timigutuzumab GEXMab73; GT-MAb7.3-GEX; TrastuzuMab-GEX	EGFR	Cancer
Timigutuzumab (GEXMab73) is a humanized monoclonal antibody that targets *ErbB2*. Timigutuzumab can be used for the research of cancer .

HY-103443A

HKI-357 dimaleate	EGFR	Cancer
HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and *ERBB2* with IC₅₀s of 34 nM and 33 nM, respectively. HKI-357 dimaleate suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation .

HY-147407

Imbotolimod	Others	Cancer
Imbotolimod, immunoglobulin G1-kappa, is a humanized monoclonal antibody with *anti-ERBB2* and antineoplastic activity. Imbotolimod is a derivative of telratolimod .

HY-20878

Tyrphostin AG 879 2 Publications Verification AG 879	Trk Receptor EGFR Apoptosis	Cancer
Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC₅₀ of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective *ErbB2* tyrosine kinase inhibitor with an IC₅₀ of 1 μM, and has at least 500-fold higher selectivity to *ErbB2* than EGFR. Tyrphostin AG 879 has anticancer activity ^[2] .

HY-50898

Lapatinib Maximum Cited Publications 68 Publications Verification GW572016; GW2016	EGFR Autophagy Ferroptosis	Cancer
Lapatinib (GW572016) is a potent inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-50898A

Lapatinib ditosylate Maximum Cited Publications 68 Publications Verification GW572016 ditosylate; GW2016 ditosylate	EGFR Autophagy Ferroptosis	Cancer
Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-50898B

Lapatinib ditosylate monohydrate Maximum Cited Publications 68 Publications Verification GW572016 ditosylate monohydrate; GW2016 ditosylate monohydrate	EGFR Autophagy Ferroptosis	Cancer
Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-50898C

Lapatinib tosylate GW572016 tosylate; GW2016 tosylate	EGFR Ferroptosis Autophagy	Cancer
Lapatinib (GW572016) tosylate is a potent, orally active inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-50898S1

Lapatinib-d7 dihydrochloride GW572016-dd₇ dihydrochloride; GW2016-dd₇ dihydrochloride	Isotope-Labeled Compounds EGFR Autophagy Ferroptosis	Cancer
Lapatinib-d₇ (dihydrochloride) is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

HY-50898S2

Lapatinib-d5 GW572016-d₅; GW2016-d₅	Isotope-Labeled Compounds EGFR Autophagy Ferroptosis	Cancer
Lapatinib-d₅ is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

HY-50898S3

Lapatinib-d4-1 GW572016-d₄-1; GW2016-d₄-1	Isotope-Labeled Compounds EGFR Autophagy Ferroptosis	Cancer
Lapatinib-d₄-1 is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

HY-137028

2′-Thioadenosine PD157432	EGFR	Cancer
2'-Thioadenosine (PD157432) is a selective and irreversible inhibitor of *ErbB-1* and *ErbB-2, with an IC₅₀* of 45 µM for ErbB-2. 2'-Thioadenosine covalently inactivates ErbB-1 via modification of a cysteine residue at the active site .

HY-50898S

Lapatinib-d4 GW572016-d₄; GW2016-d₄	EGFR Autophagy Ferroptosis	Cancer
Lapatinib-d₄ is the deuterium labeled Lapatinib (HY-50898). Lapatinib is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1][2].

HY-50898R

Lapatinib (Standard)	EGFR Autophagy Ferroptosis	Cancer
Lapatinib (Standard) is the analytical standard of Lapatinib. This product is intended for research and analytical applications. Lapatinib (GW572016) is a potent inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-164548

WK88-1	HSP Apoptosis	Cancer
WK88-1, a Hsp90 inhibitor, induces overall degradation of multiple oncogenic signaling molecules including EGFR, ErbB2 and ErbB3, leading to subsequent growth arrest and apoptosis in the Gefitinib-resistant H1975 cell line .

HY-103440

*EGFR/ErbB-2/ErbB-4 inhibitor-3*	EGFR	Cancer
EGFR/ErbB-2/ErbB-4 inhibitor-3 (compound 29) is a potent tyrosine kinase inhibitor with IC₅₀s of 0.3, 1.1, 0.5, 2.5, 24 nM for erbB1, erbB2, erbB4, EGF, HER, respectively . EGFR/ErbB-2/ErbB-4 inhibitor-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-10045

AEE788 3 Publications Verification NVP-AEE 788	EGFR Apoptosis	Cancer
AEE788 is an inhibitor of the EGFR and *ErbB2* with IC₅₀ values of 2 and 6 nM, respectively.

HY-14674

CP-724714 4 Publications Verification	EGFR Apoptosis	Cancer
CP-724714 is a potent, selective and orally active **ErbB2 (HER2) tyrosine kinase inhibitor, with an IC₅₀** of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC₅₀=6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities ^[2].

HY-N1166

Tephrosin 2 Publications Verification Deguelinol I; Hydroxydeguelin	EGFR	Cancer
Tephrosin is a natural rotenoid which has potent antitumor activities. Tephrosin induces degradation of of EGFR and *ErbB2* by inducing internalization of the receptors .

HY-100499

Tyrphostin AG 528 1 Publications Verification Tyrphostin B66; AG 528	EGFR	Cancer
Tyrphostin AG 528 is an inhibitor of EGFR and *ErbB2* with IC₅₀s of 4.9 and 2.1 μM, respectively. Tyrphostin AG 528 (Tyrphostin B66) is a protein tyrosine kinase inhibitor, with IC₅₀s of 4.9 μM for epidermal growth factor receptors (EGFR) and 2.1 μM for *ErbB2* . Tyrphostin AG 528 is also an anticancer agent ^[2].

HY-129288

GW837016X NEU-391	EGFR Paraptosis	Infection
GW837016X (NEU-391) is an orally active *ErbB-2* kinase covalent inhibitor. GW837016X also is a potent antitrypanosome agent. GW837016X inhibits mitosis and cytokinesis .

HY-13050A

Sapitinib fumarate AZD-8931 fumarate	EGFR	Cancer
Sapitinib fumarate is a reversible, ATP competitive EGFR inhibitor of with IC₅₀s of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3 in cells, respectively.

HY-160068

2-2(t) aptamer sodium	EGFR	Cancer
2-2(t) aptamer sodium is a 42-nucleotide trimeric complex of aptamer (2-2) targeting *ErbB-2*. 2-2(t) aptamer sodium inhibits the growth of gastric cancer cells in vitro and in vivo .

HY-116437

Selatinib	EGFR	Cancer
Selatinib is a reversible and orally active dual EGFR and *ErbB2* inhibitor with IC₅₀s of 13 nM and 22.5 nM, respectively. Selatinib has anticancer effects .

HY-18609

PD158780 2 Publications Verification	EGFR	Cancer
PD158780 is a potent EGFR family inhibitor with IC₅₀s of 8 pM, 49, 52, 52 nM for EGFR, ErbB2, ErbB3, and ErbB4, respectively.

HY-13050

Sapitinib 5+ Cited Publications AZD-8931	EGFR	Cancer
Sapitinib (AZD-8931) is a reversible, ATP competitive EGFR inhibitor of with IC₅₀s of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3 in cells, respectively.

HY-P990695

Lunaxafusp	EGFR	Inflammation/Immunology
Lunaxafusp is an anti-ERBB2 scFv-heavy-κ monoclonal antibody composed of a single chain variable fragment, an antibody heavy chain, and a kappa antibody light chain .

HY-13272

Dacomitinib 20+ Cited Publications PF-00299804; PF-299804	EGFR Apoptosis	Cancer
Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the *ERBB* family of kinases with IC₅₀s of 6 nM, 45.7 nM and 73.7 nM for EGFR, *ERBB2, and ERBB4*, respectively .

HY-P990697

Anvatabart ARX-788	EGFR	Inflammation/Immunology
Anvatabart is an anti-ERBB2 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-W006886

Fmoc-(R)-2-(7-octenyl)Ala-OH	Amino Acid Derivatives	Others
Fmoc-(R)-2-(7-octenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize inhibitor peptides that combinatorially inactivate ErbB1, ErbB2, and ErbB3 .

HY-32718

Pelitinib 5 Publications Verification EKB-569; WAY-EKB 569	EGFR Src	Cancer
Pelitinib (EKB-569;WAY-EKB 569) is an irreversible inhibitor of EGFR with an IC₅₀ of 38.5 nM; also slightly inhibits Src, MEK/ERK and ErbB2 with IC₅₀s of 282, 800, and 1255 nM, respectively.

HY-W008914

(E/Z)-CP-724714	EGFR	Cancer
(E/Z)-CP-724714 is a racemic compound of (E)-CP-724714 and (Z)-CP-724714 isomers. CP-724714 is a potent and selective orally active ErbB2 (HER2) inhibitor .

HY-10367A

Canertinib dihydrochloride 5+ Cited Publications CI-1033 dihydrochloride; PD-183805 dihydrochloride	EGFR Orthopoxvirus	Infection Cancer
Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and *ErbB2* autophosphorylation with IC₅₀s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice ^[2] .

HY-13896

PD168393 2 Publications Verification	EGFR Autophagy Apoptosis	Cancer
PD168393?is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and *ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC₅₀*=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC .

HY-13272S2

Dacomitinib-d10 dihydrochloride PF-00299804-d₁₀ dihydrochloride; PF-299804-d₁₀ dihydrochloride	Isotope-Labeled Compounds EGFR Apoptosis	Cancer
Dacomitinib-d₁₀ (dihydrochloride) is the deuterium labeled Dacomitinib dihydrochloride. Dacomitinib (PF-00299804) dihydrochloride is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively[1].

HY-13272S3

Dacomitinib-d10 PF-00299804-d₁₀; PF-299804-d₁₀	Isotope-Labeled Compounds EGFR Apoptosis	Cancer
Dacomitinib-d₁₀ is deuterium labeled Dacomitinib. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively[1].

HY-13272R

Dacomitinib (Standard)	EGFR Apoptosis	Cancer
Dacomitinib (Standard) is the analytical standard of Dacomitinib. This product is intended for research and analytical applications. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the *ERBB* family of kinases with IC₅₀s of 6 nM, 45.7 nM and 73.7 nM for EGFR, *ERBB2, and ERBB4*, respectively .

HY-15375

Allitinib 1 Publications Verification AST-1306; ALS 1306	EGFR	Cancer
Allitinib (AST-1306) is an orally active and irreversible EGFR and *ErbB2* inhibitor with IC₅₀s of 0.5 and 3 nM, respectively. Allitinib also inhibits *ErbB4* with an IC₅₀ of 0.8 nM. Allitinib is an anilino-quinazoline compound and has anti-cancer activity .

HY-13427

Allitinib tosylate 1 Publications Verification AST-1306 (TsOH)	EGFR	Cancer
Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and *ErbB2* inhibitor with IC₅₀s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits *ErbB4* with an IC₅₀ of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity

HY-10367

Canertinib 5+ Cited Publications CI-1033; PD-183805	EGFR Orthopoxvirus	Infection Cancer
Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and *ErbB2* autophosphorylation with IC₅₀s of 7.4 and 9 nM. Canertinib is active against vaccinia virus respiratory infection in mice ^[2] .

HY-112420

*EGFR/ErbB-2/ErbB-4 inhibitor-2*	EGFR	Cancer
EGFR/ErbB-2/ErbB-4 inhibitor-2 (Compound 5) is a EGFR and *ErbB* inhibitor with IC₅₀s of 0.017 μM, 0.08 μM, 1.91 μM .

HY-13314

Tesevatinib 4 Publications Verification XL-647; EXEL-7647; KD-019	EGFR VEGFR Ephrin Receptor	Cancer
Tesevatinib (XL-647; EXEL-7647; KD-019) is an orally available, multi-target tyrosine kinase inhibitor; inhibits EGFR, *ErbB2, KDR, Flt4* and EphB4 kinase with IC₅₀s of 0.3, 16, 1.5, 8.7, and 1.4 nM.

HY-103439

GW583340 dihydrochloride	EGFR	Cancer
GW 583340 dihydrochloride is a potent dual *EGFR/ErbB2* tyrosine kinase inhibitor (IC₅₀: 0.01 and 0.014 μM respectively). GW 583340 dihydrochloride reverses ABCG2- and ABCB1-mediated drug resistance. GW 583340 dihydrochloride has anti-cancer activity ^[2] .

Cat. No.	Product Name

HY-L074

Anti-Breast Cancer Compound Library

2,049 compounds

Breast cancer is the most frequent cancer among women, impacting 2.1 million women each year, and also causes the greatest number of cancer-related deaths among women. Surgery is usually the first type of treatment for breast cancer, which is usually followed by chemotherapy or radiotherapy or, in some cases, hormone or targeted therapies, especially for metastatic breast cancer (MBC).

Breast cancer is a heterogeneous disease, which is categorized into 3 major subtypes based on the presence or absence of molecular markers for estrogen or progesterone receptors and human epidermal growth factor 2 (ERBB2; formerly HER2): hormone receptor positive/ERBB2 negative (70% of patients), ERBB2 positive (15%-20%), and triple-negative (tumors lacking all 3 standard molecular markers; 15%). Different intrinsic subtypes exhibit different tumor behavior with different prognoses, and may require specific targeted therapies to maximize treatment effectiveness. Otherwise, some signaling pathways also play important roles in the development of breast cancer, such as NF-κB Signaling Pathway, TGF-beta Signaling Pathway, PI3K/AKT/mTOR signaling pathway and Notch Signaling Pathway. These signaling pathways offer ideal targets for development of new targeted therapies for breast cancer.

MCE supplies a unique collection of 2,049 compounds with identified and potential anti-breast cancer activity. MCE Anti-Breast Cancer Compound Library is a useful tool for anti-breast cancer drugs screening.

Cat. No.	Product Name	Target	Research Area

HY-P4082

ErbB-2-binding peptide HER2-binding peptide	EGFR	Cancer
ErbB-2-binding peptide (HER2-binding peptide) is a tumor-binding peptide. ErbB-2-binding peptide has the potential for cancer research .

HY-W006886

Fmoc-(R)-2-(7-octenyl)Ala-OH	Amino Acid Derivatives	Others
Fmoc-(R)-2-(7-octenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize inhibitor peptides that combinatorially inactivate ErbB1, ErbB2, and ErbB3 .

Cat. No.	Product Name	Target	Research Area

HY-P99558

Timigutuzumab GEXMab73; GT-MAb7.3-GEX; TrastuzuMab-GEX	EGFR	Cancer
Timigutuzumab (GEXMab73) is a humanized monoclonal antibody that targets *ErbB2*. Timigutuzumab can be used for the research of cancer .

HY-P990695

Lunaxafusp	EGFR	Inflammation/Immunology
Lunaxafusp is an anti-ERBB2 scFv-heavy-κ monoclonal antibody composed of a single chain variable fragment, an antibody heavy chain, and a kappa antibody light chain .

HY-P990697

Anvatabart ARX-788	EGFR	Inflammation/Immunology
Anvatabart is an anti-ERBB2 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1166

Tephrosin 2 Publications Verification Deguelinol I; Hydroxydeguelin	Structural Classification Flavonoids Ranunculus japonicus Thunb. Classification of Application Fields Isoflavanones Ranunculaceae Source classification Plants Disease Research Fields Cancer	EGFR
Tephrosin is a natural rotenoid which has potent antitumor activities. Tephrosin induces degradation of of EGFR and *ErbB2* by inducing internalization of the receptors .

Species:	Human (17) Rhesus Macaque (4) Rat (4) Mouse (4) Cynomolgus (3) Canine (1)
Tag:	His (20) Tag Free (2) Avi (5) Fc (9)
Source:	HEK293 (30) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P77535

	HER2/CD340 Protein, Human (Biotinylated, Domain 4, HEK293, His) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (Biotinylated, Domain 4, HEK293, His) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74895

	HER2/CD340 Protein, Rat (HEK293, His) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Rat	HEK293
	The HER2/CD340 protein is a multifunctional tyrosine kinase that is a component of the neuregulin receptor complex and regulates microtubule dynamics.Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B on the cell membrane and promotes the binding of APC and CLASP2, which is critical for microtubule stability.HER2/CD340 Protein, Rat (HEK293, His) is the recombinant rat-derived HER2/CD340 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P74897

	HER2/CD340 Protein, Canine (HEK293, His) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Canine	HEK293
	The HER2/CD340 Protein is a member of the receptor tyrosine kinase family. HER2/CD340 Protein participates in the PI3K/Akt signaling pathway to regulate the differentiation and apoptosis of neural stem cells in the cochlear nucleus. HER2/CD340 Protein is an overexpressed oncogenic factor in bladder cancer that activates the oncogenic signaling pathway, thereby promoting tumor cell survival/proliferation. HER2/CD340 Protein, Canine (HEK293, His) is the recombinant canine-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag. The total length of HER2/CD340 Protein, Canine (HEK293, His) is 630 a.a., with molecular weight of 75- 95 kDa.

HY-P72626

	HER2/CD340 Protein, Rat (His) Receptor tyrosine-protein kinase ERBB-2; p185neu; CD340; ERBB2; Neu	Rat	E. coli
	The HER2/CD340 protein is a key protein tyrosine kinase that is a component of multiple cell surface receptor complexes and requires coreceptors for ligand binding.Its interaction within the neuregulin-receptor complex depends on neuregulin, and GP30 emerges as a potential ligand.HER2/CD340 Protein, Rat (His) is the recombinant rat-derived HER2/CD340 protein, expressed by E.coli , with C-6*His labeled tag.

HY-P75805

	HER2/CD340 Protein, Cynomolgus (HEK293, His) Receptor tyrosine-protein kinase ERBB-2; p185neu; CD340; ERBB2; Neu	Cynomolgus	HEK293
	Erb-b2 receptor tyrosine kinase 2 is a member of EGFR family. Erb-b2 receptor tyrosine kinase 2 is over-expressed in the tumors of many types of cancers. Erb-b2 receptor tyrosine kinase 2 enables ATP binding and transmembrane receptor protein tyrosine kinase activity. HER2/CD340 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag. The total length of HER2/CD340 Protein, Cynomolgus (HEK293, His) is 630 a.a., with molecular weight of ~80-100 kDa.

HY-P75807

	HER2/CD340 Protein, Rhesus Macaque (HEK293, His) Receptor tyrosine-protein kinase ERBB-2; p185neu; CD340; ERBB2; Neu	Rhesus Macaque	HEK293
	The HER2/CD340 protein is a multifunctional tyrosine kinase that is a component of the neuregulin receptor complex and regulates microtubule dynamics. Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B on the cell membrane and promotes the binding of APC and CLASP2, which is critical for microtubule stability. HER2/CD340 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag. The total length of HER2/CD340 Protein, Rhesus Macaque (HEK293, His) is 629 a.a., with molecular weight of ~90-110 kDa.

HY-P77533

	HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74896

	HER2/CD340 Protein, Rat (HEK293, Fc) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Rat	HEK293
	The HER2/CD340 protein is a multifunctional tyrosine kinase that is a component of the neuregulin receptor complex and regulates microtubule dynamics.Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B on the cell membrane and promotes the binding of APC and CLASP2, which is critical for microtubule stability.HER2/CD340 Protein, Rat (HEK293, Fc) is the recombinant rat-derived HER2/CD340 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75804

	HER2/CD340 Protein, Cynomolgus (HEK293, Fc) Receptor tyrosine-protein kinase ERBB-2; p185neu; CD340; ERBB2; Neu	Cynomolgus	HEK293
	Erb-b2 receptor tyrosine kinase 2 is a member of EGFR family. Erb-b2 receptor tyrosine kinase 2 is over-expressed in the tumors of many types of cancers. Erb-b2 receptor tyrosine kinase 2 enables ATP binding and transmembrane receptor protein tyrosine kinase activity. HER2/CD340 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived HER2/CD340 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75806

	HER2/CD340 Protein, Rhesus Macaque (HEK293, Fc) Receptor tyrosine-protein kinase ERBB-2; p185neu; CD340; ERBB2; Neu	Rhesus Macaque	HEK293
	The HER2/CD340 protein is a multifunctional tyrosine kinase that is a component of the neuregulin receptor complex and regulates microtubule dynamics. Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B on the cell membrane and promotes the binding of APC and CLASP2, which is critical for microtubule stability. HER2/CD340 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived HER2/CD340 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70759

	HER2/CD340 Protein, Human (HEK293, Fc) Receptor tyrosine-protein kinase ERBB-2; Metastatic lymph node gene 19 protein; Proto-oncogene Neu; Tyrosine kinase-type cell surface receptor HER2; ERBB2; MLN19; NGL; TKR1	Human	HEK293
	HER2/CD340 Protein, Human (HEK293, Fc) is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (HEK293, Fc) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73094

	HER2/CD340 Protein, Human (HEK293) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (HEK293) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with tag free.

HY-P73097

	HER2/CD340 Protein, Rat (HEK293) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Rat	HEK293
	The HER2/CD340 Protein is a member of the receptor tyrosine kinase family.HER2/CD340 Protein participates in the PI3K/Akt signaling pathway to regulate the differentiation and apoptosis of neural stem cells in the cochlear nucleus.HER2/CD340 Protein is an overexpressed oncogenic factor in bladder cancer that activates the oncogenic signaling pathway, thereby promoting tumor cell survival/proliferation.HER2/CD340 Protein, Rat (HEK293) is the recombinant rat-derived HER2/CD340 protein, expressed by HEK293 , with tag free.

HY-P70254

	HER2/CD340 Protein, Human (HEK293, His) rHuReceptor tyrosine-protein kinase ERBB-2/HER2, His; Receptor tyrosine-protein kinase ERBB-2; Metastatic lymph node gene 19 protein; Proto-oncogene Neu; Tyrosine kinase-type cell surface receptor HER2; ERBB2; MLN19; NGL; TKR1	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (HEK293, His) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73929

	HER2/CD340 Protein, Mouse (HEK293, His) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Mouse	HEK293
	The HER2/CD340 protein is a multifunctional tyrosine kinase that is a component of the neuregulin receptor complex and regulates microtubule dynamics. Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B on the cell membrane and promotes the binding of APC and CLASP2, which is critical for microtubule stability. HER2/CD340 Protein, Mouse (HEK293, His) is the recombinant mouse-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag. The total length of HER2/CD340 Protein, Mouse (HEK293, His) is 631 a.a., with molecular weight of 100-110 kDa.

HY-P73930

	HER2/CD340 Protein, Mouse (HEK293, Fc) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Mouse	HEK293
	The HER2/CD340 protein is a multifunctional tyrosine kinase that is a component of the neuregulin receptor complex and regulates microtubule dynamics. Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B on the cell membrane and promotes the binding of APC and CLASP2, which is critical for microtubule stability. HER2/CD340 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived HER2/CD340 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of HER2/CD340 Protein, Mouse (HEK293, Fc) is 631 a.a., with molecular weight of 120-130 kDa.

HY-P73929A

	HER2/CD340 Protein, Mouse (HEK293, N-His) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Mouse	HEK293
	The HER2/CD340 protein is a multifunctional tyrosine kinase that is a component of the neuregulin receptor complex and regulates microtubule dynamics. Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B on the cell membrane and promotes the binding of APC and CLASP2, which is critical for microtubule stability. HER2/CD340 Protein, Mouse (HEK293, N-His) is the recombinant mouse-derived HER2/CD340 protein, expressed by HEK293 , with N-His labeled tag. The total length of HER2/CD340 Protein, Mouse (HEK293, N-His) is 631 a.a., with molecular weight of 80-100 kDa.

HY-P72374

	HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc-Avi) Proto-oncogene Neu; Tyrosine kinase-type cell surface receptor ERBB2; MLN19; NGL; TKR1	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag.

HY-P73095

	HER2/CD340 Protein, Human (Domain 4, HEK293, His) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (142a.a, HEK293, His) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73931

	HER2/CD340 Protein, Human (Biotinylated, 173a.a, HEK293, His) Receptor tyrosine-protein kinase ERBB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (Biotinylated, 173a.a, HEK293, His) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700887

	HER2/CD340 Protein, Cynomolgus (Biotinylated, HEK293, His) CD340; EGFR2; ERBB2; HER2; HER-2; herstatin; MLN 19; MLN19; NGL; TKR1; ERBB2; NEU; ENV; ENVW; ERVWE1; HERV7Q; HERVW	Cynomolgus	HEK293
	Erb-b2 receptor tyrosine kinase 2 is a member of EGFR family. Erb-b2 receptor tyrosine kinase 2 is over-expressed in the tumors of many types of cancers. Erb-b2 receptor tyrosine kinase 2 enables ATP binding and transmembrane receptor protein tyrosine kinase activity. HER2/CD340 Protein, Cynomolgus (Biotinylated, HEK293, His) is the recombinant cynomolgus-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag. The total length of HER2/CD340 Protein, Cynomolgus (Biotinylated, HEK293, His) is 630 a.a., with molecular weight of 85-105 kDa.

HY-P78138

	HER2/CD340 Protein, Human (Biotinylated, HEK293, His-Avi) CD340; EGFR2; ERBB2; HER2; HER-2; herstatin; MLN 19; MLN19; Neu Oncogene; NEUHER-2/neu; NGL; p185ERBB2; TKR1; ERBB2; HER-2/neu; NEU; ENV; ENVW; ERVWE1; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78451

	HER2/CD340 Protein, Human (HEK293, His-Avi) CD340; EGFR2; ERBB2; HER2; HER-2; herstatin; MLN 19; MLN19; Neu Oncogene; NEUHER-2/neu; NGL; p185ERBB2; TKR1; ERBB2; HER-2/neu; NEU; ENV; ENVW; ERVWE1; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (HEK293, His-Avi) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78453

	HER2/CD340 Protein, Human (Domain 4, HEK293, His-Avi) CD340; EGFR2; ERBB2; HER2; HER-2; herstatin; MLN 19; MLN19; Neu Oncogene; NEUHER-2/neu; NGL; p185ERBB2; TKR1; ERBB2; HER-2/neu; NEU; ENV; ENVW; ERVWE1; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (142a.a, HEK293, His-Avi) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P700643

	HER2/CD340 Protein, Human (Biotinylated, Domain 4, HEK293, His-Avi) CD340; EGFR2; ERBB2; HER2; HER-2; herstatin; MLN 19; MLN19; Neu Oncogene; NEUHER-2/neu; NGL; p185ERBB2; TKR1; ERBB2; HER-2/neu; NEU; ENV; ENVW; ERVWE1; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (Biotinylated, 142a.a, HEK293, His-Avi) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P78882

	Her2/CD340 Protein, Human (Biotinylated, HEK293, His) ERBB2; CD340; HER-2; neu; HER2; MLN19; NEU; NGL; TKR1	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. Her2/CD340 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Her2/CD340 protein, expressed by HEK293 , with C-His labeled tag.

HY-P701268

	FITC-Labeled HER2/CD340 Protein, Human (HEK293, Fc) ERBB2; CD340; HER-2; neu; HER2; MLN19; NEU; NGL; TKR1	Human	HEK293
	FITC-Labeled HER2/CD340 Protein, Human (HEK293, Fc) is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. FITC-Labeled HER2/CD340 Protein, Human (HEK293, Fc), expressed by HEK293 , with Fc labeled tag.

HY-P78680

	HER2/CD340 Protein, Human (S310Y, HEK293, His) ERBB2; CD340; HER-2/neu; HER2; MLN19; NEU; NGL; TKR1	Human	HEK293
	The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (S310Y, HEK293, His) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-10*His labeled tag and S310Y, , , , mutation.

HY-P703899

	ERBB4/Her4 Protein, Human, (hFc) erb-b2 receptor tyrosine kinase 4	Human;Rhesus Macaque	HEK293

HY-P703900

	ERBB4/Her4 Protein, Human, (His) erb-b2 receptor tyrosine kinase 4	Human;Rhesus Macaque	HEK293

HY-P702533

	Neuregulin-1/NRG1 Protein, Mouse (HEK293, His) ARIA; GGF2; GGFglial growth factor; Heregulin-1; HGL; HGLneu differentiation factor; HRG; HRG1; HRG1-alpha; HRG1-beta 1; HRGAneuregulin 1 type IV beta 1a; MST131; MSTP131; NDFheregulin, alpha (45kD, ERBB2 p185-activator); neuregulin 1 type IV beta 3; neuregulin 1; Neuregulin1; Neuregulin-1; NRG1; pro-neuregulin-1, membrane-bound isoform; pro-NRG1; sensory and motor neuron derived factor; SMDF	Mouse	HEK293
	NRG1 Protein is a direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells. Binds to ERBB4 and ERBB3. Neuregulin-1/NRG1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Neuregulin-1/NRG1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Neuregulin-1/NRG1 Protein, Mouse (HEK293, His) is 227 a.a..

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