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Results for "

Eyes

" in MedChemExpress (MCE) Product Catalog:

25

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12798
    Netarsudil

    AR-13324

    		 Monoamine Transporter ROCK Neurological Disease
    Netarsudil is a Rho kinase (ROCK) and norepinephrine transporter (NET) inhibitor. Netarsudil increases outflow facility in human eyes through multiple mechanisms .
    Netarsudil
  • HY-113756A
    Latanoprost acid
    1 Publications Verification

    		 Prostaglandin Receptor Inflammation/Immunology
    Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor . Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes .
    Latanoprost acid
  • HY-A0079
    Tetracaine

    Amethocaine

    		 Sodium Channel Neurological Disease
    Tetracaine is a long-acting amino-ester used to prevent pain and induce anesthesia for the eyes; works by interfering with entry of sodium ions into nerve cells.
    Tetracaine
  • HY-12798A
    Netarsudil dimesylate

    AR-13324 dimesylate

    		 ROCK Others
    Netarsudil mesylate (AR-13324 mesylate) is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.
    Netarsudil dimesylate
  • HY-133860
    Chrysoobtusin

    		Others Others
    Chrysoobtusin is an anthraquinone derivative isolated from Semen Cassiae. Semen Cassiae has long been used to protect liver, brighten eyes, and relieve constipation .
    Chrysoobtusin
  • HY-W707056
    Latanoprost acid-d4

    		Biochemical Assay Reagents Others
    Latanoprost acid-d4 is used as the internal standard in the HPLC-MS/MS analysis to determine the level of Latanoprost acid (HY-113756A) in aqueous humor samples of eyes .
    Latanoprost acid-d4
  • HY-113756AR
    Latanoprost acid (Standard)

    		Prostaglandin Receptor Inflammation/Immunology
    Latanoprost acid (Standard) is the analytical standard of Latanoprost acid. This product is intended for research and analytical applications. Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor . Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes .
    Latanoprost acid (Standard)
  • HY-121902
    Butidrine

    		Others Others
    Butidrine is a compound with intraocular pressure-lowering activity that is less effective than some other beta-adrenergic receptor blockers in reducing intraocular pressure in rabbit eyes.
    Butidrine
  • HY-12720B
    Apraclonidine dihydrochloride

    ALO 2145 dihydrochloride

    		 Adrenergic Receptor Neurological Disease
    Apraclonidine (ALO 2145) dihydrochloride, a selective α2 and weak α1 receptor agonist activity, effectively low intraocular pressure (IOP) in eyes. Apraclonidine dihydrochloride is a topical ophthalmic solution .
    Apraclonidine dihydrochloride
  • HY-12720
    Apraclonidine

    ALO 2145 free base

    		 Adrenergic Receptor Infection Neurological Disease
    Apraclonidine (ALO 2145 (free base)), a selective α2 and weak α1 receptor agonist activity, effectively low intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution .
    Apraclonidine
  • HY-B0397
    Dichlorphenamide
    1 Publications Verification

    Diclofenamide

    		 Carbonic Anhydrase Neurological Disease
    Dichlorphenamide (Diclofenamide) is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research .
    Dichlorphenamide
  • HY-B0397A
    Dichlorphenamide disodium

    Diclofenamide disodium

    		 Carbonic Anhydrase Neurological Disease
    Dichlorphenamide (Diclofenamide) disodium is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research .
    Dichlorphenamide disodium
  • HY-162592
    EYA2-IN-1

    		Phosphatase Cancer
    EYA2-IN-1(compound 2e) is a novel allosteric EYA2 inhibitor. EYA2-IN-1 has anti-tumor activity .
    EYA2-IN-1
  • HY-12720A
    Apraclonidine hydrochloride
    2 Publications Verification

    ALO 2145

    		 Adrenergic Receptor Neurological Disease
    Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid .
    Apraclonidine hydrochloride
  • HY-78035
    Citraconic anhydride

    Methylmaleic anhydride

    		 Biochemical Assay Reagents Others
    Citraconic anhydride (Methylmaleic anhydride) is a derivative of maleic anhydride. Citraconic anhydride is utilized to block the proteins amino groups reversibly, stabilizes certain enzymes and improves their catalytic performance, or to reverse the effects of formalin fixation in tissue sections. Citraconic anhydride is irritating for skin and eyes .
    Citraconic anhydride
  • HY-116420
    ROCK2-IN-8

    		ROCK Neurological Disease
    ROCK2-IN-8 (Compound 1) is an orally active ROCK2 inhibitor, with an IC50 of 7.2 nM. ROCK2-IN-8 can be used for the research of aqueous humor outflow in porcine eyes and myosin light chain phosphorylation .
    ROCK2-IN-8
  • HY-119063
    L-645151

    		Carbonic Anhydrase Others
    L-645151 is a carbonic anhydrase inhibitor with ocular penetration and hypotensive activity. L-645151 lowers the elevated intraocular pressure (IOP) of o-chymotripsinized (o-CT) rabbit eyes. L-645151 is promising for research of an ocular hypotensive agent .
    L-645151
  • HY-101303
    5-MCA-NAT

    		Melatonin Receptor Others
    5-MCA-NAT is a melatonin agonist that may target the melatoninMT3 receptor. 5-MCA-NAT can contract the colonic band in a concentration-dependent manner and reduce intraocular pressure (IOP) in glaucomatous monkey eyes, inhibiting the increase in IOP .
    5-MCA-NAT
  • HY-127012
    H-0104 dihydrochloride

    		Others Others
    H-0104 dihydrochloride is a ROCK inhibitor with significant intraocular pressure (IOP)-lowering activity. H-0104 dihydrochloride effectively reduces IOP when administered to monkey eyes. There may not be a direct relationship between the Iop-lowering effect of H-0104 dihydrochloride and ROCK inhibition .
    H-0104 dihydrochloride
  • HY-B0999
    Chlorindanol

    Clorindanol; 7-Chloro-4-indanol

    		 Bacterial Infection
    Chlorindanol (7-Chloro-4-indanol) is a topical antiseptic or sanitizer. Chlorindanol is rapidly lethal to vegetative bacteria, Trichophyton sp., C. albicans, E. histolytica cysts and trophozoites, T. vaginalis, and spermatozoa in vitro. Chlorindanol is klow systemic toxicity, well skin/eyes/genital mucosa tolerance and nonallergenic.
    Chlorindanol
  • HY-P0095
    Acetyl tetrapeptide-5

    		Angiotensin-converting Enzyme (ACE) Others
    Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care .
    Acetyl tetrapeptide-5
  • HY-12720AR
    Apraclonidine hydrochloride (Standard)

    		Adrenergic Receptor Neurological Disease
    Apraclonidine (hydrochloride) (Standard) is the analytical standard of Apraclonidine (hydrochloride). This product is intended for research and analytical applications. Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid .
    Apraclonidine hydrochloride (Standard)
  • HY-113600
    H-0106 dihydrochloride

    		Others Others
    H-0106 dihydrochloride is a ROCK inhibitor with potent intraocular pressure (IOP)-lowering activity. H-0106 dihydrochloride can effectively inhibit ROCK enzyme. H-0106 dihydrochloride demonstrated significant IOP-lowering effects in monkey eyes. Studies with H-0106 dihydrochloride suggest that there may not be a direct relationship between ROCK inhibition and IOP reduction .
    H-0106 dihydrochloride
  • HY-135774
    6-Hydroxybenzbromarone

    		Drug Metabolite Phosphatase Cardiovascular Disease
    6-Hydroxybenzbromarone is the major metabolite of Benzbromarone with a longer half-life and greater pharmacological potency than the parent compound. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor with an IC50 value of 21.5 μM. 6-Hydroxybenzbromarone is an anti-angiogenic agent, has strong inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting .
    6-Hydroxybenzbromarone
  • HY-W016568
    Isoxanthopterin

    		Others Others
    Isoxanthopterin is a heterocyclic compound belonging to the pteridine family and its activity is mainly reflected in its optical properties. Isoxanthopterin can form a reflective layer in the eyes of animals, enhancing visual function. The main regulatory mechanism of isoxanthopterin involves its ability to form a crystalline structure within organisms, which achieves a high refractive index through specific hydrogen bonding patterns and molecular arrangements. Isoxanthopterin can be used for research in materials science and optical engineering .
    Isoxanthopterin

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