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Results for "

HSL

" in MedChemExpress (MCE) Product Catalog:

44

Inhibitors & Agonists

4

Biochemical Assay Reagents

2

Peptides

9

Natural
Products

2

Isotope-Labeled Compounds

2

Antibodies

5

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-164714
    HSL-IN-5

    		Lipase
    HSL-IN-5 (Example 21) is a hormone sensitive lipase (HSL) inhibitor (IC50: 0.25 μM). HSL-IN-5 can be used for diabetes research .
    HSL-IN-5
  • HY-23524
    HSL-IN-3
    1 Publications Verification

    		 Lipase Others
    HSL-IN-3 (example 42), a boronic acid ester derivative, is an inhibitor of hormone-sensitive lipase (HSL) .
    HSL-IN-3
  • HY-101509
    HSL-IN-1
    3 Publications Verification

    		 Lipase Metabolic Disease
    HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability .
    HSL-IN-1
  • HY-118697
    N-dodecanoyl-L-Homoserine lactone
    1 Publications Verification

    C12-HSL

    		 Bacterial Infection
    N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-dodecanoyl-L-Homoserine lactone
  • HY-141641
    N-(3-Oxopentanoyl)-L-homoserine lactone

    HSL

    		 Bacterial Infection
    N-(3-Oxopentanoyl)-L-homoserine lactone is an autoinducer, a kind of chemical signal molecule which passively diffuses across the bacterial envelope and accumulates intracellularly at high bacterial densities. It may bind to a protein related to the LuxR protein of V. fischeri and causes cell density-dependent gene expression. N-(3-Oxopentanoyl)-L-homoserine can be used for research of quorum sensing .
    N-(3-Oxopentanoyl)-L-homoserine lactone
  • HY-RS25107
    Lipe Rat Pre-designed siRNA Set A

    HSL; REH

    		 Small Interfering RNA (siRNA) Others

    Lipe Rat Pre-designed siRNA Set A contains three designed siRNAs for Lipe gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Lipe Rat Pre-designed siRNA Set A
    Lipe Rat Pre-designed siRNA Set A
  • HY-RS18621
    Lipe Mouse Pre-designed siRNA Set A

    HSL; REH; 4933403G17Rik

    		 Small Interfering RNA (siRNA) Others

    Lipe Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lipe gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Lipe Mouse Pre-designed siRNA Set A
    Lipe Mouse Pre-designed siRNA Set A
  • HY-RS07687
    LIPE Human Pre-designed siRNA Set A

    HSL; LHS; REH; AOMS4; FPLD6

    		 Small Interfering RNA (siRNA) Others

    LIPE Human Pre-designed siRNA Set A contains three designed siRNAs for LIPE gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    LIPE Human Pre-designed siRNA Set A
    LIPE Human Pre-designed siRNA Set A
  • HY-RS03587
    DCPS Human Pre-designed siRNA Set A

    ARS; DCS1; HSL1; HINT5; HINT-5; HSPC015

    		 Small Interfering RNA (siRNA) Others

    DCPS Human Pre-designed siRNA Set A contains three designed siRNAs for DCPS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DCPS Human Pre-designed siRNA Set A
    DCPS Human Pre-designed siRNA Set A
  • HY-RS11174
    PRMT5 Human Pre-designed siRNA Set A

    HSL7; JBP1; SKB1; IBP72; SKB1Hs; HRMT1L5

    		 Small Interfering RNA (siRNA) Others

    PRMT5 Human Pre-designed siRNA Set A contains three designed siRNAs for PRMT5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PRMT5 Human Pre-designed siRNA Set A
    PRMT5 Human Pre-designed siRNA Set A
  • HY-W685561
    3-Oxo-C8-HSL

    N-(3-Oxooctanoyl)-l-homoserine lactone

    		 Biochemical Assay Reagents Infection
    3-Oxo-C8-HSL (N-(3-Oxooctanoyl)-l-homoserine lactone) is an autoinducer pheromone. 3-Oxo-C8-HSL is a TraR-regulated promoter. 3-Oxo-C8-HSL significantly stimulates tra gene expression .
    3-Oxo-C8-HSL
  • HY-118697R
    N-Dodecanoyl-L-homoserine lactone (Standard)

    C12-HSL (Standard)

    		 Reference Standards Bacterial Infection
    N-dodecanoyl-L-Homoserine lactone (Standard) (C12-HSL (Standard)) is the analytical standard of N-dodecanoyl-L-Homoserine lactone (HY-118697). This product is intended for research and analytical applications. N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
    N-Dodecanoyl-L-homoserine lactone (Standard)
  • HY-120242
    N-(3-Oxobutanoyl)-L-homoserine lactone

    		Antibiotic Infection
    N-(3-Oxobutanoyl)-L-homoserine lactone (3-oxo-C4-HSL) is a carbapenem antibiotic biosynthesis autoregulator in Erwinia carotovora ATCC 39048. N-(3-Oxobutanoyl)-L-homoserine lactone induces expression of rhiI in R. leguminosarum .
    N-(3-Oxobutanoyl)-L-homoserine lactone
  • HY-134560
    N-(3-Oxodecanoyl)-L-homoserine lactone

    3-Oxo-C10-HSL

    		 Bacterial Inflammation/Immunology
    N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) is a bacterial quorum sensing signal autoinducer molecule .
    N-(3-Oxodecanoyl)-L-homoserine lactone
  • HY-116536
    N-3-Oxo-tetradecanoyl-L-homoserine lactone

    oxo-C14-HSL

    		 Bacterial Infection
    N-3-Oxo-tetradecanoyl-L-homoserine lactone (oxo-C14-HSL) is a rhizobacterial inducer and can improve basic defense against nematodes .
    N-3-Oxo-tetradecanoyl-L-homoserine lactone
  • HY-145492
    Δ7(Z)-C14-HSL

    N-(3-Oxo-7Z-tetradecenoyl)-L-homoserine lactone

    		 Others Inflammation/Immunology
    Δ7(Z)-C14-HSL (Compound 12) is an immunosuppressive agent that can inhibit the proliferation of mouse splenic cells with an IC50 of 17 μM. Δ7(Z)-C14-HSL can be used for further studying its potential as a molecular mechanism in TNF-R-driven immune diseases, especially autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes .
    Δ7(Z)-C14-HSL
  • HY-114816R
    N-Butanoyl-L-homoserine lactone (Standard)

    C4-HSL (Standard); N-Butyryl-L-homoserine lactone (Standard)

    		 Reference Standards ADC Linker Bacterial Infection Inflammation/Immunology Cancer
    N-Butanoyl-L-homoserine lactone (Standard) (C4-HSL (Standard)) is the analytical standard of N-Butanoyl-L-homoserine lactone (HY-114816). This product is intended for research and analytical applications. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
    N-Butanoyl-L-homoserine lactone (Standard)
  • HY-136409
    N-Decanoyl-L-homoserine lactone

    C10-HSL

    		 Bacterial Reactive Oxygen Species (ROS) Infection
    N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca 2+ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .
    N-Decanoyl-L-homoserine lactone
  • HY-158730
    N-3-Hydroxybutyryl-L-homoserine lactone

    3-OH-C4-HSL; N-3-Hydroxybutanoyl-L-homoserine lactone; N-3-Hydroxybutyryl-L-HSL

    		 Bacterial Infection
    N-3-Hydroxybutyryl-L-homoserine lactone (3-OH-C4-HSL) is an acyl-homoserine lactone, that can be isolated from Vibrionaceae. N-3-Hydroxybutyryl-L-homoserine lactone is a signaling molecule that is involved in bacterial quorum sensing (QS). N-3-Hydroxybutyryl-L-homoserine lactone senses the density of bacterial population, regulates the cellular process, such as bioluminescence, biofilm formation, and exo-enzyme production .
    N-3-Hydroxybutyryl-L-homoserine lactone
  • HY-113764
    N-Butanoyl-DL-homoserine lactone

    (Rac)-C4-HSL

    		 Bacterial Infection Inflammation/Immunology
    N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-Butanoyl-DL-homoserine lactone
  • HY-114816
    N-Butanoyl-L-homoserine lactone
    1 Publications Verification

    C4-HSL; N-Butyryl-L-homoserine lactone

    		 ADC Linker Bacterial Infection Inflammation/Immunology
    N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm . N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-Butanoyl-L-homoserine lactone
  • HY-124286
    N-cis-Tetradec-9Z-enoyl-L-homoserine lactone

    C14-9Z-HSL

    		 Bacterial Inflammation/Immunology
    N-cis-Tetradec-9Z-enoyl-L-homoserine lactone (C14-9Z-HSL) is an autoinducer in C. rodentium, that serves as signal molecule, coordinates the gene expression and behaviors through diffusion into cells of different bacterial species .
    N-cis-Tetradec-9Z-enoyl-L-homoserine lactone
  • HY-133685S
    N-Hexanoyl-L-Homoserine lactone-d3

    C6-HSL-d3

    		 Isotope-Labeled Compounds Bacterial Infection Metabolic Disease
    N-Hexanoyl-L-Homoserine lactone-d3 (C6-HSL-d3) is deuterium labeled N-Hexanoyl-L-homoserine lactone. N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats .
    N-Hexanoyl-L-Homoserine lactone-d3
  • HY-N10192
    Aculene D

    		Endogenous Metabolite Bacterial Infection
    Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .
    Aculene D
  • HY-153523
    Hi 76-0079

    NNC0076-0079; 76-0079

    		 Lipase Metabolic Disease
    Hi 76-0079 (Compound 31) is a hormone-sensitive lipase (HSL) inhibitor with an IC50 of 184 nM .
    Hi 76-0079
  • HY-102056
    BAY 59-9435
    3 Publications Verification

    		 Lipase Metabolic Disease
    BAY 59-9435 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC50 of 0.023 μM.
    BAY 59-9435
  • HY-159170
    Quorum sensing-IN-7

    		Bacterial Infection
    Quorum sensing-IN-7 (compound HSL 4) is a potent quorum sensing (QS) inhibitor. Quorum sensing-IN-7 interacts with Leu 72 and Gln 95 in the CviR binding pocket. Quorum sensing-IN-7, an antibacterial agent, is highly effective at inhibiting the production of homoserine lactones (HSLs) and biofilm in C. violaceum at 0.25-1 mg/mL .
    Quorum sensing-IN-7
  • HY-W243002
    Acetyl-L-homoserine lactone

    		Bacterial Infection
    Acetyl-L-homoserine lactone is a member of the family of N-acylated homoserine lactones (HSLs). Acetyl-L-homoserine lactone is a polar mediator of cell-cell interactions in bacterial biofilms .
    Acetyl-L-homoserine lactone
  • HY-114816S
    N-butyryl-L-Homoserine lactone-d5

    		Isotope-Labeled Compounds ADC Linker Bacterial Infection Inflammation/Immunology
    N-butyryl-L-Homoserine lactone-d5 is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm . N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-butyryl-L-Homoserine lactone-d5
  • HY-114544A
    N-3-oxo-dodecanoyl-L-homoserine lactone

    OdDHL

    		 Bacterial NF-κB ERK Caspase Reactive Oxygen Species (ROS) Apoptosis Metabolic Disease Inflammation/Immunology Cancer
    N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex .Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells .
    N-3-oxo-dodecanoyl-L-homoserine lactone
  • HY-W127487
    N-Octadecanoyl-L-homoserine lactone

    		Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C18-HSL, one of four lipophilic long acyl side chain AHLs produced by the LuxI AHL synthase homolog SinI, is involved in quorum-sensing signaling in strains of Rhizobium meliloti (a nitrogen-fixing bacterial symbiont of the legume M. sativa) . C18-HSL and other hydrophobic AHLs tend to localize in the relatively lipophilic environment of bacterial cells and cannot diffuse freely across the cell membrane. Long-chain N-acyl homoserine lactones can be exported from cells by efflux pumps, or can be transported between communicating cells by extracellular outer membrane vesicles.
    N-Octadecanoyl-L-homoserine lactone
  • HY-136409R
    N-Decanoyl-L-homoserine lactone (Standard)

    C10-HSL (Standard)

    		 Reference Standards Bacterial Reactive Oxygen Species (ROS) Infection
    Formoterol (hemifumarate hydrate) (Standard) is the analytical standard of Formoterol (hemifumarate hydrate). This product is intended for research and analytical applications. Formoterol hemifumarate hydrate is a selective, long-acting beta 2-adrenoceptor agonist. Formoterol is a bronchodilator used for the research of the asthma and chronic obstructive pulmonary disease (COPD). Formoterol hemifumarate hydrate induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury .
    N-Decanoyl-L-homoserine lactone (Standard)
  • HY-15483
    DY131
    3 Publications Verification

    GSK 9089

    		 Estrogen Receptor/ERR Smo Endocrinology Cancer
    DY131 (GSK 9089) is a potent and selective ERRγ and ERRβ agonist. DY131displays inactive against ERRα, ERα and ERβ . DY131 also inhibits Smo signaling .
    DY131
  • HY-113764R
    N-Butanoyl-DL-homoserine lactone (Standard)

    		Bacterial Infection Inflammation/Immunology
    N-Butanoyl-DL-homoserine lactone (Standard) is the analytical standard of N-Butanoyl-DL-homoserine lactone. This product is intended for research and analytical applications. N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-Butanoyl-DL-homoserine lactone (Standard)
  • HY-113801
    N-(3-Oxooctanoyl)-DL-homoserine lactone

    (Rac)-3-oxo-C8-HSL

    		 Endogenous Metabolite Metabolic Disease
    N-(3-Oxooctanoyl)-DL-homoserine lacton is a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, with stereochemistry-dependent growth regulatory activity for roots .
    N-(3-Oxooctanoyl)-DL-homoserine lactone
  • HY-114773
    N-Undecanoyl-L-homoserine lactone

    		Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.
    N-Undecanoyl-L-homoserine lactone
  • HY-W127393
    N-Nonanoyl-L-homoserine lactone

    		Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in nutrient-rich Luria-Bertani broth (LB) medium.
    N-Nonanoyl-L-homoserine lactone
  • HY-113801R
    N-(3-Oxooctanoyl)-DL-homoserine lactone (Standard)

    (Rac)-3-oxo-C8-HSL (Standard)

    		 Endogenous Metabolite Reference Standards Metabolic Disease
    4-Epitetracycline (hydrochloride) (Standard) is the analytical standard of 4-Epitetracycline (hydrochloride). This product is intended for research and analytical applications. 4-Epitetracycline hydrochloride is an epimer of Tetracycline (HY-A0107). Tetracycline can undergo epimerization in solution to 4-Epitetracycline hydrochloride, which shows a much lower antibiotic activity .
    N-(3-Oxooctanoyl)-DL-homoserine lactone (Standard)
  • HY-D0846
    Diethyl pyrocarbonate

    		Biochemical Assay Reagents Neurological Disease
    Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues. Diethyl pyrocarbonate can be used for modeling .
    Diethyl pyrocarbonate
  • HY-N1420A
    Rhamnose monohydrate

    L-Rhamnose monohydrate

    		 Endogenous Metabolite MMP Interleukin Related PKA Infection Metabolic Disease Cancer
    Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .
    Rhamnose monohydrate
  • HY-N1420
    Rhamnose

    L-Rhamnose

    		 Endogenous Metabolite MMP Interleukin Related PKA Infection Metabolic Disease Cancer
    Rhamnose (L-Rhamnose ) is an orally active deoxysugar. Rhamnose can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .
    Rhamnose
  • HY-P1210
    Lys-γ3-MSH(human)

    		Melanocortin Receptor Endocrinology
    Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC50 of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .
    Lys-γ3-MSH(human)
  • HY-N1420AR
    Rhamnose monohydrate (Standard)

    L-Rhamnose monohydrate (Standard)

    		 Reference Standards Endogenous Metabolite MMP Interleukin Related PKA Infection Metabolic Disease Cancer
    Rhamnose monohydrate (Standard) is the analytical standard of Rhamnose monohydrate (HY-N1420A). Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .
    Rhamnose monohydrate (Standard)
  • HY-P1210A
    Lys-γ3-MSH(human) TFA

    		Melanocortin Receptor Endocrinology
    Lys-γ3-MSH(human) TFA is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) TFA potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) TFA is a potent stimulator of lipolysis with an apparent EC50 of 3.56 nM. Lys-γ3-MSH(human) TFA can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .
    Lys-γ3-MSH(human) TFA

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