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Hydrogenated soya phosphatidylcholines is a natural product. Hydrogenated soya phosphatidylcholines can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs .
Balixafortide TFA (POL6326 TFA) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide TFA shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide TFA blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide TFA is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects .
BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels .
BIO5192 is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels .
Cyclosporin H is a selective and potent inhibitor of FPR-1 (formyl peptide receptor 1). Cyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin (HY-10219) or Prostaglandin E2 (HY-101952). Cyclosporin H lacks immunosuppressant activity of Cyclosporin A.
ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4), which functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 activates the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. ATI-2341 is a potent and efficacious mobilizer of bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) .
Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects .
ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4), which functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 activates the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. ATI-2341 is a potent and efficacious mobilizer of bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) .
Hydrogenated soya phosphatidylcholines is a natural product. Hydrogenated soya phosphatidylcholines can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs .
Balixafortide TFA (POL6326 TFA) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide TFA shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide TFA blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide TFA is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects .
Cyclosporin H is a selective and potent inhibitor of FPR-1 (formyl peptide receptor 1). Cyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin (HY-10219) or Prostaglandin E2 (HY-101952). Cyclosporin H lacks immunosuppressant activity of Cyclosporin A.
ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4), which functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 activates the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. ATI-2341 is a potent and efficacious mobilizer of bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) .
Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects .
ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4), which functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 activates the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. ATI-2341 is a potent and efficacious mobilizer of bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) .
Hydrogenated soya phosphatidylcholines is a natural product. Hydrogenated soya phosphatidylcholines can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs .
CRIPT, a pivotal member of the minor spliceosome, plays a crucial role in U12-type intron splicing, contributing to RNA splicing intricacies. Beyond its splicing function, CRIPT anchors DLG4 within excitatory synapses, interacts with RNF113A, SF3B1/SF3b155, SF3B2/SF3b145, and PHF5A/SF3b14b in the minor spliceosome complex, and strongly associates with the PDZ3 domain of DLG4 family members, highlighting its synaptic involvement. Additionally, CRIPT interacts with microtubules, indicating a role in cytoskeletal dynamics, showcasing its multifaceted contributions. CRIPT Protein, Human (His) is the recombinant human-derived CRIPT protein, expressed by E. coli, with N-His labeled tag. The total length of CRIPT Protein, Human (His) is 101 a.a., with molecular weight of ~14 kDa.
COMMD9 protein regulates the cullin-RING E3 ubiquitin ligase (CRL) complex and regulates ubiquitin-dependent protein degradation. It downregulates NF-kappa-B activation and affects immune and inflammatory responses. COMMD9 Protein, Human (His) is the recombinant human-derived COMMD9 protein, expressed by E. coli , with N-6*His labeled tag.
HSP90b Protein, Human (Sf9) is the recombinant human-derived HSP90b, expressed by Sf9 insect cells , with tag Free labeled tag. The total length of HSP90b Protein, Human (Sf9) is 724 a.a.,
HSP90b Protein, Human (Sf9, His, Strep) is the recombinant human-derived HSP90b, expressed by Sf9 insect cells , with Strep, His labeled tag. The total length of HSP90b Protein, Human (Sf9, His, Strep) is 724 a.a.,
TRMT112 protein activates various methyltransferases for rRNA, tRNA, and protein modifications. It cooperates with BUD23 to methylate guanine N(7) of 18S rRNA. TRMT112 Protein, Human (His-SUMO) is the recombinant human-derived TRMT112 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
The LGALSL protein was identified as a member of the galectin family, exhibits no affinity for lactose, and may not be involved in carbohydrate binding. This unique feature distinguishes LGALSL from typical galectins, which are known for their carbohydrate recognition domain and interaction with specific sugar moieties. LGALSL Protein, Human (His) is the recombinant human-derived LGALSL protein, expressed by E. coli , with C-6*His labeled tag. The total length of LGALSL Protein, Human (His) is 171 a.a., with molecular weight of ~18.0 kDa.
JTB proteins are critical for normal cytokinesis progression, regulate cell proliferation, and may serve as components of the chromosomal passenger complex (CPC) during mitosis. It interacts with key CPC components, affects AURKB activity, and exhibits anti-apoptotic properties, inhibiting TGFB1-induced apoptosis. JTB Protein, Human (HEK293, Fc) is the recombinant human-derived JTB protein, expressed by HEK293 , with C-mFc labeled tag. The total length of JTB Protein, Human (HEK293, Fc) is 75 a.a., with molecular weight of ~38 kDa.
The PHPT1 protein acts as a phosphohistidine phosphatase, catalyzing the dephosphorylation of phosphohistidine residues. This unique enzymatic activity makes PHPT1 a regulator of histidine phosphorylation events, suggesting that it is involved in signaling pathways or cellular processes that are critical for phosphohistidine modification. PHPT1 Protein, Human (His) is the recombinant human-derived PHPT1 protein, expressed by E. coli , with N-His labeled tag.
LAMTOR2 is a key component of the Ragulator complex, which centralizes amino acid sensing and mTORC1 activation in response to stimuli such as growth factors, energy levels, and amino acids. As an amino acid-activated guanine nucleotide exchange factor (GEF), the Ragulator complex recruits Rag GTPases (RagA/RRAGA, RagB/RRAGB, RagC/RRAGC, and/or RagD/RRAGD) to the lysosomal membrane. LAMTOR2 Protein, Human (His) is the recombinant human-derived LAMTOR2 protein, expressed by E. coli , with N-His labeled tag.
The PHPT1 protein acts as a phosphohistidine phosphatase, catalyzing the dephosphorylation of phosphohistidine residues. This unique enzymatic activity makes PHPT1 a regulator of histidine phosphorylation events, suggesting that it is involved in signaling pathways or cellular processes that are critical for phosphohistidine modification. PHPT1 Protein, Human (P.pastoris, His) is the recombinant human-derived PHPT1 protein, expressed by P. pastoris , with N-His labeled tag.
Protein kinase D2 (PRKD2) is a serine/threonine protein kinase that mediates various cellular processes downstream of PKC. It affects cell proliferation through MAPK1/3 (ERK1/2) signaling, activates NF-kappa-B under oxidative stress, inhibits HDAC7 transcriptional repression, and regulates T cell antigen receptor (TCR) signaling, cytokine production, Golgi trafficking, angiogenesis, particle release, and cell adhesion. Protein Kinase D2/PRKD2 Protein, Human (sf9, His-GST) is the recombinant human-derived protein Kinase D2/PRKD2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
TRAT1 protein stabilizes the T-cell antigen receptor (TCR)/CD3 complex on T-cell surfaces. As a homodimer linked by disulfide bonds, TRAT1 interacts with CD3Z, enhancing the structural integrity and function of the TCR/CD3 complex. Phosphorylated TRAT1 also engages with PIK3R1, indicating its role in signaling pathways related to T-cell activation and response. TRAT1 Protein, Human (His) is the recombinant human-derived TRAT1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of TRAT1 Protein, Human (His) is 158 a.a., with molecular weight of ~30.0 kDa.
SAE1 protein, forming a heterodimer, acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and potentially SUMO4. It critically mediates ATP-dependent activation of SUMO proteins, enabling the formation of a thioester bond with UBA2/SAE2's active site cysteine. This process is essential for protein modification through sumoylation. SAE1 Protein, Human (GST) is the recombinant human-derived SAE1 protein, expressed by E. coli , with N-GST labeled tag. The total length of SAE1 Protein, Human (GST) is 346 a.a., with molecular weight of ~65.4 kDa.
BZW2 is a translation initiation regulator that inhibits non-AUG and RAN-initiated translation. As a competitive inhibitor of EIF5, it improves initiation accuracy by preventing EIF5-dependent translation of non-AUG codons. BZW2 Protein, Human (GST) is the recombinant human-derived BZW2 protein, expressed by E. coli , with N-GST labeled tag.
BACE1 protein is crucial in proteolytic processing of amyloid precursor protein (APP), initiating cleavage at the N-terminus of the A-beta peptide sequence.This process results in the extracellular release of beta-cleaved soluble APP and a cell-associated C-terminal fragment.BACE1's cleavage activity extends to CHL1, demonstrating its versatility in substrate processing.BACE1 Protein, Human (HEK293, Fc) is the recombinant human-derived BACE1 protein, expressed by HEK293 , with C-hFc labeled tag.
The HSP90AA1 protein is an important molecular chaperone that coordinates the maturation and regulation of specific target proteins critical for cell cycle control and signal transduction. Its ATPase activity drives a functional cycle that induces conformational changes in client proteins for activation. HSP90AA1 Protein, Human (His-SUMO) is the recombinant human-derived HSP90AA1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
Heat shock protein HSP 90-alpha; Heat shock 86 kDa (HSP 86; HSP86); Heat shock protein family C member 1; Lipopolysaccharide-associated protein 2 (LAP-2; LPS-associated protein 2); Renal carcinoma antigen NY-REN-38; HSP90A, HSPC1, HSPCA
The HSP90AA1 protein is an important molecular chaperone that coordinates the maturation and regulation of specific target proteins critical for cell cycle control and signal transduction. Its ATPase activity drives a functional cycle that induces conformational changes in client proteins for activation. HSP90AA1 Protein, Human (His, Avi) is the recombinant human-derived HSP90AA1, expressed by E. coli , with C-Avi, C-6*His labeled tag. ,
PKD2 Antibody (YA1730) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1730), targeting PKD2, with a predicted molecular weight of 97 kDa (observed band size: 105 kDa). PKD2 Antibody (YA1730) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse background.
UFC1 Antibody (YA2347) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2347), targeting UFC1, with a predicted molecular weight of 19 kDa (observed band size: 19 kDa). UFC1 Antibody (YA2347) can be used for WB, IHC-P experiment in human, mouse, rat background.
FOXP1 Antibody (YA1283) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1283), targeting FOXP1. FOXP1 Antibody (YA1283) can be used for IHC-P experiment in human background.
SLP2 Antibody (YA1720) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1720), targeting SLP2, with a predicted molecular weight of 39 kDa (observed band size: 39 kDa). SLP2 Antibody (YA1720) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.
Switch Associated Protein 70 Antibody (YA1073) is a mouse-derived non-conjugated IgG2b antibody (Clone NO.: YA1073), targeting Switch Associated Protein 70, with a predicted molecular weight of 69 kDa (observed band size: 69 kDa). Switch Associated Protein 70 Antibody (YA1073) can be used for WB, IP experiment in human, mouse, rat, monkey background.
NDUFAF4 Antibody (YA3302) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3302), targeting NDUFAF4, with a predicted molecular weight of 20 kDa (observed band size: 20 kDa). NDUFAF4 Antibody (YA3302) can be used for WB, ICC/IF, IP experiment in human background.
APOM; G3A; NG20; HSPC336; Apolipoprotein M; Apo-M; ApoM; Protein G3a
WB, IHC-P, FC
Human
ApoM Antibody (YA2580) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2580), targeting ApoM, with a predicted molecular weight of 21 kDa (observed band size: 25 kDa). ApoM Antibody (YA2580) can be used for WB, IHC-P, FC experiment in human background.
Phospho-PRKD2 (Ser876) Antibody (YA1662) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1662), targeting Phospho-PRKD2 (Ser876), with a predicted molecular weight of 97 kDa (observed band size: 105 kDa). Phospho-PRKD2 (Ser876) Antibody (YA1662) can be used for WB, IP experiment in human background.
MRPS18B Antibody (YA3082) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3082), targeting MRPS18B, with a predicted molecular weight of 29 kDa (observed band size: 29 kDa). MRPS18B Antibody (YA3082) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.
AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38
WB, IP
Human, Mouse, Rat
AHA1 Antibody (YA2023) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2023), targeting AHA1, with a predicted molecular weight of 38 kDa (observed band size: 42 kDa). AHA1 Antibody (YA2023) can be used for WB, IP experiment in human, mouse, rat background.
Hsp90 alpha/beta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 85 kDa, targeting to Hsp90 alpha/beta. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.
OTUB1 Antibody (YA1483) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1483), targeting OTUB1, with a predicted molecular weight of 31 kDa (observed band size: 31 kDa). OTUB1 Antibody (YA1483) can be used for WB, IP experiment in human, mouse, rat background.
Y14 Antibody (YA2439) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2439), targeting Y14, with a predicted molecular weight of 20 kDa (observed band size: 20 kDa). Y14 Antibody (YA2439) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.
Hydrogenated soya phosphatidylcholines is a natural product. Hydrogenated soya phosphatidylcholines can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs .
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