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Results for "

NO sensor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) AIM2 (1) Bacterial (6) Biochemical Assay Reagents (3) Cyclic GMP-AMP Synthase (1) Estrogen Receptor/ERR (1) Ferroptosis (1) Fluorescent Dye (16) Fungal (1) GPR68 (1) Sodium Channel (1)
By Research Areas:	Cancer (6) Infection (8) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (4)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Targets Recommended: NO Synthase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0982

Zinquin	Fluorescent Dye	Others
Zinquin is a fluorescent sensor and used to observe reactive Zn ²⁺.λex/λem=368/490 nm.

HY-101900

Nile Blue A sulfate Nile blue sulfate	Fluorescent Dye	Others
Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .

HY-153917

CRT0063465	Others	Metabolic Disease Cancer
CRT0063465 is a Ligand of HumanPGK1andStress Sensor DJ1, with theK_dof 24 μM ofPGK1. CRT0063465 modulates the shelterin complex composition and telomere Length .

HY-126774

DAF-FM	Fluorescent Dye	Others
DAF-FM is a diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance .

HY-155254

Sodium ionophore VI	Others	Others
Sodium ionophore VI is a sodium ionophore that has been employed for developing cation optical sensors .

HY-D1441

Zinquin AM ester	Fluorescent Dye	Others
Zinquin AM ester is an AM ester form of Zinquin. Zinquin, a fluorescent dye, is a commonly used sensor for cellular Zn ²⁺ status .

HY-162158

DA ZP1	Fluorescent Dye	Others
DA ZP1 is a fluorogenic Zn(II) sensor (K_d Zn ²⁺ = 0.6 nM) . Ex / Em = 490 / 522 nm

HY-123727

Acid blue 120	Fluorescent Dye	Others
Acid blue 120 is an azo dye, which can be utilized in textile dyeing, food and pharmaceutical coloring, photosensitizer, sensor and surface modification .

HY-W111999

1-Benzyl-3-phenylthiourea	Others	Neurological Disease
1-Benzyl-3-phenylthiourea is a sensor material for detecting nerve agents and related simulants, and has biosensor activity. 1-Benzyl-3-phenylthiourea can be used to increase the sensitivity of sensors to nerve agents and enhance detection capabilities. The reaction characteristics of 1-Benzyl-3-phenylthiourea are similar to those of nerve agents and their simulants, making it show good results in detection .

HY-D2335

SERTlight	Fluorescent Dye	Neurological Disease
SERTlight is a fluorescent agent that can specifically label serotonergic neuronal cell bodies, dendrites, and axonal projections as fluorescent substrates of the serotonin transporter (SERT). SERTlight is orthogonal to various genetically encoded sensors in terms of optics, pharmacology, and operation, enabling multiple imaging. SERTlight allows the use of GRAB_5HT sensors to label distal 5HT axonal projections and simultaneously image the release of endogenous 5HT, providing a new multifunctional molecular tool for studying serotonergic systems .

HY-D0140

Chromoionophore I ETH 5294	Fluorescent Dye	Others
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble .

HY-119516

Naftalofos	Others	Others
Naftalofos is a phosphate compound that can be used to prepare glassy carbon electrodes modified with modified reduced graphene oxide/chitosan composites. Naftalofos sensors can be used in the detection of food and environmental samples .

HY-115658

VU0420373	Bacterial	Infection Metabolic Disease
VU0420373 is a potent *heme sensor* system (HssRS) activator with an EC₅₀ of 10.7 μM and a pEC₅₀** of 4.97. VU0420373 induces heme biosynthesis, and is toxic to fermenting S. aureus .

HY-B2182

Bismuth subcarbonate Bismuth carbonate oxide	Bacterial	Infection
Bismuth subcarbonate (Bismuth carbonate oxide) is a typical Bi-based semiconductor that is widely applied as antibacterial, sensors, super capacitors, and photocatalysts. Bismuth subcarbonate protects the gastric ulcer from further erosion by gastric acid .

HY-123414

GX-936 PF-05196233	Sodium Channel	Neurological Disease
GX-936 (PF-05196233), a potent and Nav1.7-subtype selective inhibitor, binds to the activated state of voltage-sensor domain IV (VSD4) .

HY-154954

Ogremorphin OGM; GPR68-IN-1	GPR68 Ferroptosis	Inflammation/Immunology Cancer
Ogremorphin (OGM) is a G protein coupled sensor GPR68 inhibitor with anti-inflammatory and anti-tumor activities. Ogremorphin can inhibit the migration of human melanoma cells and induce ferroptosis in glioblastoma cells .

HY-D1563

CypHer 5	Fluorescent Dye	Others
CypHer 5 is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. CypHer 5 has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. CypHer 5 has been used as a pH sensor of lysosomal compartments .

HY-W089777

3-Glycidyloxypropyltrimethoxysilane GPTMS	Biochemical Assay Reagents	Others
3-Glycidyloxypropyltrimethoxysilane (GPTMS) is the silicon source for the preparation of inorganic–organic hybrid polymers, which is used for hard coatings of organic polymers, contact lens materials in the optical industry, electronics, membranes, sensors, nanoimprinting, wave guides, and biology .

HY-12825

BHPI	Estrogen Receptor/ERR	Cancer
BHPI is a potent inhibitor of nuclear estrogen–ERα-regulated gene expression; elicits sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor, the unfolded protein response (UPR), and persistent inhibition of protein synthesis.

HY-D1264

PMQA Zn-green	Fluorescent Dye	Others
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn ²⁺-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn ²⁺ in living cells .

HY-W110905

Naphthol green B	Fluorescent Dye	Others
Naphthol green B is an iron-complex dye. Naphthol green B can be used in wool dyeing, silk dyeing and polyamide dyeing. Naphthol green B can be used to fabricate electrochemical sensor for the detection of H₂O₂ .

HY-121310

Phthalocyanine	Bacterial	Infection Cancer
Phthalocyanine is a photosensitizer. Phthalocyanine has a light-killing effect on bacterial biofilms, effectively inactivating bacteria. Phthalocyanine can be linked to anticancer drugs to target cancer. Phthalocyanine can also be used to develop chemical sensors for studying microbial infections and tumors .

HY-D0156

ZnAF-1	Fluorescent Dye	Others
ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry .

HY-131007

FFN270 hydrochloride	Adrenergic Receptor	Metabolic Disease
FFN270 hydrochloride, a fluorescent tracer of norepinephrine, is a fluorescent substrate of the norepinephrine and vesicular monoamine transporters. FFN270 hydrochloride exhibits two resolved absorption/excitation maxima depending on solvent pH (FFN270 ex: 320 nm or 365 nm, em: 475 nm) and can function as ratiometric fluorescent pH-sensors .

HY-120972

Pentafluorobenzenesulfonyl fluorescein	Others	Others
Pentafluorobenzenesulfonyl fluorescein is a H₂O₂-selective sensor that can be used to detect H₂O₂ levels in cells. Pentafluorobenzenesulfonyl fluorescein is normally non-fluorescent but fluoresces upon perhydrolysis of the sulfonyl linkage by H₂O₂ .

HY-D1677

5(6)-Carboxynaphthofluorescein	Fluorescent Dye	Others
5(6)-Carboxynaphthofluorescein is a pH-dependent fluorophore. 5(6)-Carboxynaphthofluorescein shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. 5(6)-Carboxynaphthofluorescein can be used as a fluorescent pH indicator (Ex/Em=593/668 nm) .

HY-B2182R

Bismuth subcarbonate (Standard)	Bacterial	Infection
Bismuth subcarbonate (Standard) is the analytical standard of Bismuth subcarbonate. This product is intended for research and analytical applications. Bismuth subcarbonate (Bismuth carbonate oxide) is a typical Bi-based semiconductor that is widely applied as antibacterial, sensors, super capacitors, and photocatalysts. Bismuth subcarbonate protects the gastric ulcer from further erosion by gastric acid .

HY-114505

3-Hydroxypentadecane-4-one	Others	Infection
3-Hydroxypentadecane-4-one (LAI-1; Legionella autoinducer-1) is a quorum sensing signaling molecule by Legionella pneumophila. 3-Hydroxypentadecane-4-one is an autoinducer, which affects the intercellular communication between bacteria through sensor kinases, LqsS, LqsT and LqsR .

HY-B1571

Bromophenol blue	Fluorescent Dye	Others
Bromophenol blue is an acid phthalein dye, and it is used as a tracking dye for electrophoresis. Bromophenol blue is also used as a pH indicator, with a transition range of pH 3 to 4.6. Bromophenol blue is used as a sensor for the determination of several compounds including ammonia, drugs, proteins and amino acids. The binding of Bromophenol blue to proteins is accompanied by the appearance of a strong absorbance at 610 nm .

HY-121503

FD44	Others	Neurological Disease
FD44 is a phenothiazine small molecule that inhibits the interaction between neuronal calcium sensor 1 (NCS-1) and the guanine exchange factor Ric8a, a key regulator of synapse number and neurotransmitter release probability. In the Drosophila genetic autism model of fragile X syndrome (FXS), FD44 restored normal synapse number and associative learning .

HY-D2264

Caffeine orange	Fluorescent Dye	Others
Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices 。

HY-W008709

4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol	Biochemical Assay Reagents	Others
4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol is an organic compound commonly used in fluorescent dyes and catalysts. It can be used to prepare some organic light-emitting diodes (OLEDs) and organic solar cells, and is widely used in chemical sensors and analytical instruments. In addition, this compound is used as a catalyst or buffer in certain chemical reactions.

HY-W105135

2,6-Dichloroquinone-4-chloroimide	Biochemical Assay Reagents	Others
2,6-Dichloroquinone-4-chloroimide is a spray reagent for organic compounds. 2,6-Dichloroquinone-4-chloroimide can be used in thin-layer chromatograms and detecting phenol and its derivatives. 2,6-Dichloroquinone-4-chloroimide can be used as an optical sensor for rapid detection of permethrin in treated wood .

HY-118487

OB-24 1 Publications Verification	Others	Cancer
OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA) .

HY-138646

Poly(deoxyadenylic-thymidylic) acid sodium Poly(dA:dT) sodium	Cyclic GMP-AMP Synthase AIM2	Infection Cancer
Polydeoxyadenylic-thymidylic acid (Poly(dA:dT)) sodium is a synthetic DNA polymer. Poly(dA:dT) sodium can be used to determine the activity of bound and free ribonucleic acid polymerase. Poly(dA:dT) sodium is recognized by multiple PRRs (cytosolic DNA sensors (CDS), including cGAS, AIM2, DAI, DDX41, IFI16, and LRRFIP1), and triggers the production of type I interferons. Poly(dA:dT) sodium can be used for the research of cancer and virus infection .

HY-117005

C450-0730	Bacterial	Infection
C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxN ^I209F was not significant .

HY-D1065

NIR-H2O2	Fluorescent Dye	Inflammation/Immunology
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H₂O₂ with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H₂O₂ in living cells and mice .

HY-126637

Marasmic acid	Bacterial Fungal	Infection
Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.

HY-W251144

N,N′-Dipentyl-3,4,9,10-perylenedicarboximide PTCDI-C5	Others
N,N′-Dipentyl-3,4,9,10-perylenedicarboximide (PTCDI-C5) is an organic semiconductor compound with excellent electron transport activity. N,N′-Dipentyl-3,4,9,10-perylenedicarboximide exhibits high performance in organic field effect transistors (OFETs) and can effectively improve the carrier mobility of the device. The application of N,N′-Dipentyl-3,4,9,10-perylenedicarboximide in organic photovoltaic (OPV) materials enhances the light absorption performance, thereby improving the photoelectric conversion efficiency. N,N′-Dipentyl-3,4,9,10-perylenedicarboximide has also been widely studied for the development of high-performance sensors and fluorescent materials.

Cat. No.	Product Name

HY-L175

Inflammasomes related Compound Library	80 compounds
Inflammasomes are classic pattern recognition receptors for natural immune responses. Inflammasomes are polymeric protein complexes that regulate inflammatory responses and pyrolytic cell death, thereby exerting the host's defense against microorganisms. Inflammasomes sensors are associated with adapter proteins, activating inflammatory caspase-1, releasing inflammatory cytokines and inducing cell death, endowing the host with defense against pathogens. NLRP1, NLRP3, NLRC4, AIM2, and pyrin are considered typical inflammasomes because they convert cysteine asparaginase-1 into catalytically active capsaicin-1. In addition to infectious diseases, the importance of inflammasomes is also related to various clinical diseases, such as autoimmune diseases, neurodegeneration and metabolic disorders, and the development of cancer. Therefore, it is necessary to strictly regulate the activation and function of inflammasomes to avoid accidental host tissue damage while inducing pathogens to kill the inflammatory response. MCE designs a unique collection of 80 inflammasomes related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.

Inflammasomes related Compound Library

80 compounds

Inflammasomes are classic pattern recognition receptors for natural immune responses. Inflammasomes are polymeric protein complexes that regulate inflammatory responses and pyrolytic cell death, thereby exerting the host's defense against microorganisms. Inflammasomes sensors are associated with adapter proteins, activating inflammatory caspase-1, releasing inflammatory cytokines and inducing cell death, endowing the host with defense against pathogens. NLRP1, NLRP3, NLRC4, AIM2, and pyrin are considered typical inflammasomes because they convert cysteine asparaginase-1 into catalytically active capsaicin-1. In addition to infectious diseases, the importance of inflammasomes is also related to various clinical diseases, such as autoimmune diseases, neurodegeneration and metabolic disorders, and the development of cancer. Therefore, it is necessary to strictly regulate the activation and function of inflammasomes to avoid accidental host tissue damage while inducing pathogens to kill the inflammatory response.

MCE designs a unique collection of 80 inflammasomes related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.

Cat. No.	Product Name	Type

HY-D0982

Zinquin	Fluorescent Dyes/Probes
Zinquin is a fluorescent sensor and used to observe reactive Zn ²⁺.λex/λem=368/490 nm.

HY-101900

Nile Blue A sulfate Nile blue sulfate	Fluorescent Dyes/Probes
Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .

HY-D1563

CypHer 5	Dyes
CypHer 5 is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. CypHer 5 has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. CypHer 5 has been used as a pH sensor of lysosomal compartments .

HY-D0156

ZnAF-1	Fluorescent Dyes/Probes
ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry .

HY-B1571

Bromophenol blue

Dyes

Bromophenol blue is an acid phthalein dye, and it is used as a tracking dye for electrophoresis. Bromophenol blue is also used as a pH indicator, with a transition range of pH 3 to 4.6. Bromophenol blue is used as a sensor for the determination of several compounds including ammonia, drugs, proteins and amino acids. The binding of Bromophenol blue to proteins is accompanied by the appearance of a strong absorbance at 610 nm .

HY-126774

DAF-FM	Fluorescent Dyes/Probes
DAF-FM is a diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance .

HY-123727

Acid blue 120	Dyes
Acid blue 120 is an azo dye, which can be utilized in textile dyeing, food and pharmaceutical coloring, photosensitizer, sensor and surface modification .

HY-D2335

SERTlight

Dyes

SERTlight is a fluorescent agent that can specifically label serotonergic neuronal cell bodies, dendrites, and axonal projections as fluorescent substrates of the serotonin transporter (SERT). SERTlight is orthogonal to various genetically encoded sensors in terms of optics, pharmacology, and operation, enabling multiple imaging. SERTlight allows the use of GRAB_5HT sensors to label distal 5HT axonal projections and simultaneously image the release of endogenous 5HT, providing a new multifunctional molecular tool for studying serotonergic systems .

HY-D0140

Chromoionophore I ETH 5294	Fluorescent Dyes/Probes
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble .

HY-D1264

PMQA Zn-green	Fluorescent Dyes/Probes
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn ²⁺-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn ²⁺ in living cells .

HY-D2264

Caffeine orange

Fluorescent Dyes/Probes

Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices 。

HY-D1065

NIR-H2O2	Fluorescent Dyes/Probes
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H₂O₂ with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H₂O₂ in living cells and mice .

Cat. No.	Product Name	Type

HY-W089777

3-Glycidyloxypropyltrimethoxysilane GPTMS	Biochemical Assay Reagents
3-Glycidyloxypropyltrimethoxysilane (GPTMS) is the silicon source for the preparation of inorganic–organic hybrid polymers, which is used for hard coatings of organic polymers, contact lens materials in the optical industry, electronics, membranes, sensors, nanoimprinting, wave guides, and biology .

HY-121310

Phthalocyanine	Indicators
Phthalocyanine is a photosensitizer. Phthalocyanine has a light-killing effect on bacterial biofilms, effectively inactivating bacteria. Phthalocyanine can be linked to anticancer drugs to target cancer. Phthalocyanine can also be used to develop chemical sensors for studying microbial infections and tumors .

HY-W008709

4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol	Biochemical Assay Reagents
4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol is an organic compound commonly used in fluorescent dyes and catalysts. It can be used to prepare some organic light-emitting diodes (OLEDs) and organic solar cells, and is widely used in chemical sensors and analytical instruments. In addition, this compound is used as a catalyst or buffer in certain chemical reactions.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-126637

Marasmic acid	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Fungal
Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.

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NO sensor

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

NaturalProducts

Natural
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