Search Result

Results for "

PH change

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (1) Biochemical Assay Reagents (10) Cytochrome P450 (1) Fluorescent Dye (15) Influenza Virus (2) Pim (1)
By Research Areas:	Cancer (6) Endocrinology (1) Infection (2) Metabolic Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Targets Recommended: HIF/HIF Prolyl-Hydroxylase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W011271

PIPES monosodium 1,4-Piperazinediethanesulfonic acid monosodium	Biochemical Assay Reagents	Others
PIPES (1,4-Piperazinediethanesulfonic acid) monosodium is a pH buffer that can be mixed with another disodium salt form of PIPES. By changing the ratio and total amount of the PIPES monosodium and disodium buffers, the pH and ionic strength of the medium can be changed .

HY-D0219A

Thymol Blue sodium	Fluorescent Dye	Others
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6 .

HY-D0219

Thymol blue ThymolsulPHonePHthalein	Fluorescent Dye	Others
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6 . Storage: protect from light.

HY-D2119

CQ-Lyso	Fluorescent Dye	Cancer
CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes .

HY-D0169A

Phenol Red sodium salt 1 Publications Verification PHenolsulfonePHthalein sodium salt	Fluorescent Dye	Others
Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .

HY-20794

8-Hydroxyjulolidine	Fluorescent Dye	Others
8-Hydroxyjulolidine is a chromophore moiety of a fluorescent probe for the detection of weak acid ions. 8-Hydroxyjulolidine can be used to synthesize the salicylaldehyde derivative 9-formyl-8-hydroxyjulolidine, which exhibits sensitive detection ability to pH changes of hydrogen sulfide and silicate in aqueous solution .

HY-W110789

Ethyl Orange (sodium), indicator grade	Biochemical Assay Reagents	Others
Ethyl Orange (sodium), indicator grade is an organic azo compound that can be used as a pH indicator from pH 3.0 to pH 4.8, changing color from red to orange.

HY-D0011

Brom0phenol blue sodium	Biochemical Assay Reagents	Others
Bromophenol blue sodium is a pH indicator. It changes from yellow at pH 3.0 to blue at pH 4.6. Bromophenol blue sodium is also used as a tracking dye to monitor the process of agarose gel electrophoresis and polyacrylamide gel electrophoresis .

HY-W110790

Bromocresol purple sodium	Biochemical Assay Reagents	Others
Bromocresol purple (sodium) is a water-soluble dye, bromocresol purple sodium, commonly known as bromocresol purple, used as a pH indicator. The dye color changes from yellow to purple between pH 5.2 and 6.8.

HY-W923277

Sodium sesquicarbonate hydrate	Biochemical Assay Reagents
Sodium sesquicarbonate hydrate is a kind of buffering agent that can stabilize pH value by neutralizing acidic substances without causing a sharp change in pH value. This property makes it widely used in many fields, especially in maintaining acid-base balance in organisms.

HY-D0169

Phenol Red 1 Publications Verification PHenolsulfonePHthalein	Fluorescent Dye	Others
Phenol red (Phenolsulfonephthalein) is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .

HY-W087928

Bromocresol purple	Biochemical Assay Reagents	Others
Bromocresol purple is a pH indicator, whose color changes from yellow to purple when the pH increases from 5.2 to 6.8. Bromocresol purple can be used for detecting yeast cells with plasma membrane damage .

HY-W087913

alpha-Naphtholphthalein	Biochemical Assay Reagents	Others
alpha-Naphtholphthalein is an indicator that is light yellow at pH 6 and gradually shows a clear color change with increasing pH to light green-green-blue. alpha-Naphtholphthalein can be impregnated into cotton-blend fabrics and used to develop medical supplies for wound pH monitoring, such as medical gauze, hospital gowns and compression bandages .

HY-128545

Nitrazine yellow Nitrazine paper; PHenaPHthazine	Biochemical Assay Reagents	Others
Nitrazine yellow (Nitrazine paper; Phenaphthazine) is a pH indicator. The color of Nitrazine yellow changes from yellow to blue in the pH range from 6.0 to 7.0. Nitrazine yellow is a kind of biological materials or organic compounds that are widely used in life science research .

HY-128369

Acid Yellow 36 Metanil Yellow	Cytochrome P450	Others
Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. Acid Yellow 36 is used in the leather, paper and textile industries. Acid Yellow 36 acts as a bifunctional inducer of specific isozymes of P-450 and cytosolic enzymes .

HY-155717

NDBM	Autophagy Pim	Cancer
NDBM is a probe and binds to tumor-specific Pim-1 kinase, releases strong fluorescence, and produces cytotoxicity, thus achieving cell screening and killing effects. NDBM can specifically target lysosomes and sensitively respond to pH. NDBM can be used to track the pH changes in the intracellular environment under conditions of autophagy and external stimulation .

HY-145391

Triperiden	Influenza Virus	Infection
Triperiden is an inhibitor of influenza virus multiplication. Triperiden targets the haemagglutinin of fowl plague virus (FPV) for antiviral activity and acts by inhibiting the conformational change in the haemagglutinin at acid pH. Triperiden is also anticholinergic anti-parkinsonism agent .

HY-D0228

4-(4-Nitrophenylazo)resorcinol Azo Violet; Magneson I	Fluorescent Dye	Others
4-(4-Nitrophenylazo)resorcinol is an azo purple dye used experimentally as a pH indicator, showing yellow when the pH value is lower than 11 and purple when the pH value is higher than 13. In slightly alkaline or alkaline environments, it also turns dark blue in the presence of magnesium salts. Azo Violet can also be used to test for the presence of ammonium ions. The color of the ammonium chloride or ammonium hydroxide solution will change depending on the concentration of azo violet used.

HY-118907

Methyl Orange	Fluorescent Dye	Others
Methyl Orange is a soluble azo dye commonly used as an acid-base indicator and for staining cells and tissue sections, as well as for dyeing textiles. Methyl Orange appears red at a pH of 3.1 and changes to bright yellow as the pH increases to 4.4. Methyl Orange (500 mg/L) exhibits cytotoxicity and can cause DNA damage .

HY-118155

9-Amino-6-chloro-2-methoxyacridine	Fluorescent Dye	Others
9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H ⁺/solute antiport system .

HY-D0227F

THAM hydrochloride (≥99%, reagent grade) 1 Publications Verification Tris HCl (≥99%, reagent grade); Tris hydrochloride (≥99%, reagent grade)	Biochemical Assay Reagents	Others
THAM hydrochloride (≥99%, reagent grade), also known as Tris-HCl, is a buffer commonly used in various biochemical and molecular biology applications to maintain a stable pH environment. Tris-HCl has unique chemical properties that allow it to resist changes in pH when acidic or basic substances are added, which makes it useful for stabilizing biological samples or reagents. It is commonly used in electrophoresis and protein purification procedures.

HY-W110798

Bromophenol blue indicator (3.0-4.6)	Biochemical Assay Reagents	Others
Bromophenol blue indicator (3.0-4.6) is a synthetic dye commonly used as an acid-base indicator with a transition range of pH 3.0-4.6. Bromophenol blue indicator (3.0-4.6) is water soluble and changes color from yellow to blue as the pH of the solution changes from acidic to basic. Its unique chemical properties make it an important ingredient in a variety of scientific applications, especially in biochemistry and molecular biology. In addition, it can be used as a stain in microbiology and histology. However, Bromophenol blue indicator (3.0-4.6) has potential irritating and staining properties.

HY-110257

BDY FL-X, SE	Fluorescent Dye	Others
BODIPY FL-X,SE is a fluorescent greendye for the labeling of amine, shows a high fluorescence quantum yield and is relatively insensitive to pH change. BODIPY FL-X,SE can be used as an alternative for FAM, Cy2 or FITC. λ_abs: 504 nm; λ_em:510 nm .

HY-114352

BODIPY FL-X	Fluorescent Dye	Others
BODIPY FL-X is a green-fluorescent dye. BODIPY FL-X has the succinimidyl ester covalently coupled to proteins. BODIPY FL-X has high fluorescence quantum yield and is relatively insensitive to pH change. (λ_ex=504 nm, λ_em=510 nm) .

HY-118907R

Methyl Orange (Standard)	Fluorescent Dye	Others
Methyl Orange (Standard) is the analytical standard of Methyl Orange. This product is intended for research and analytical applications. Methyl Orange is a soluble azo dye commonly used as an acid-base indicator and for staining cells and tissue sections, as well as for dyeing textiles. Methyl Orange appears red at a pH of 3.1 and changes to bright yellow as the pH increases to 4.4. Methyl Orange (500 mg/L) exhibits cytotoxicity and can cause DNA damage .

HY-N8502

Urdamycin A	Fluorescent Dye	Cancer
Urdamycin A (Compound 3b) is an angucycline antibiotic that can be isolated from Streptomyces fradiae. Urdamycin A is an orange indicator with a change of the color to ultramarine blue at pH 7.7. Urdamycin A has anticancer activity with IC₅₀s of 2.4 and 0.55 μg/mL in proliferation and stem cell assays, respectively .

HY-D2379

HMRG	Fluorescent Dye	Endocrinology Cancer
HMRG is a type of hydroxymethyl rhodamine green fluorescent scaffold, featuring an open non-cyclic structure. HMRG can produce significant dynamic fluorescence changes through a one-step enzymatic reaction at physiological pH, which is useful for developing various probes. Fluorescent probes based on HMRG can be used for fluorescence detection of diseases such as tumors and diabetic nephropathy .

HY-116182

RO5487624	Influenza Virus	Infection
RO5487624, an analogue of RO5464466 (HY-120690), is an orally active hemagglutinin (HA) inhibitor of influenza H1N1 viruses that abolishes influenza virus fusion by blocking HA conformational changes in low pH environments. RO5487624 displays a protective effect on mice that are lethally challenged with influenza H1N1 virus .

HY-D1560

FG 488 DHPE	Fluorescent Dye	Others
FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well .

Cat. No.	Product Name	Type

HY-D0219A

Thymol Blue sodium	Fluorescent Dyes/Probes
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6 .

HY-D0219

Thymol blue ThymolsulPHonePHthalein	Fluorescent Dyes/Probes
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6 . Storage: protect from light.

HY-D2119

CQ-Lyso	Fluorescent Dyes/Probes
CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes .

HY-D0169A

Phenol Red sodium salt 1 Publications Verification PHenolsulfonePHthalein sodium salt	Dyes
Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .

HY-D0169

Phenol Red 1 Publications Verification PHenolsulfonePHthalein	Dyes
Phenol red (Phenolsulfonephthalein) is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .

HY-128369

Acid Yellow 36 Metanil Yellow	Dyes
Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. Acid Yellow 36 is used in the leather, paper and textile industries. Acid Yellow 36 acts as a bifunctional inducer of specific isozymes of P-450 and cytosolic enzymes .

HY-118155

9-Amino-6-chloro-2-methoxyacridine	Fluorescent Dyes/Probes
9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H ⁺/solute antiport system .

HY-110257

BDY FL-X, SE	Fluorescent Dyes/Probes
BODIPY FL-X,SE is a fluorescent greendye for the labeling of amine, shows a high fluorescence quantum yield and is relatively insensitive to pH change. BODIPY FL-X,SE can be used as an alternative for FAM, Cy2 or FITC. λ_abs: 504 nm; λ_em:510 nm .

HY-D0228

4-(4-Nitrophenylazo)resorcinol Azo Violet; Magneson I	Dyes
4-(4-Nitrophenylazo)resorcinol is an azo purple dye used experimentally as a pH indicator, showing yellow when the pH value is lower than 11 and purple when the pH value is higher than 13. In slightly alkaline or alkaline environments, it also turns dark blue in the presence of magnesium salts. Azo Violet can also be used to test for the presence of ammonium ions. The color of the ammonium chloride or ammonium hydroxide solution will change depending on the concentration of azo violet used.

4-(4-Nitrophenylazo)resorcinol

Azo Violet; Magneson I

Dyes

4-(4-Nitrophenylazo)resorcinol is an azo purple dye used experimentally as a pH indicator, showing yellow when the pH value is lower than 11 and purple when the pH value is higher than 13. In slightly alkaline or alkaline environments, it also turns dark blue in the presence of magnesium salts. Azo Violet can also be used to test for the presence of ammonium ions. The color of the ammonium chloride or ammonium hydroxide solution will change depending on the concentration of azo violet used.

HY-114352

BODIPY FL-X	Fluorescent Dyes/Probes
BODIPY FL-X is a green-fluorescent dye. BODIPY FL-X has the succinimidyl ester covalently coupled to proteins. BODIPY FL-X has high fluorescence quantum yield and is relatively insensitive to pH change. (λ_ex=504 nm, λ_em=510 nm) .

HY-D2379

HMRG	Fluorescent Dyes/Probes
HMRG is a type of hydroxymethyl rhodamine green fluorescent scaffold, featuring an open non-cyclic structure. HMRG can produce significant dynamic fluorescence changes through a one-step enzymatic reaction at physiological pH, which is useful for developing various probes. Fluorescent probes based on HMRG can be used for fluorescence detection of diseases such as tumors and diabetic nephropathy .

HMRG

Fluorescent Dyes/Probes

HMRG is a type of hydroxymethyl rhodamine green fluorescent scaffold, featuring an open non-cyclic structure. HMRG can produce significant dynamic fluorescence changes through a one-step enzymatic reaction at physiological pH, which is useful for developing various probes. Fluorescent probes based on HMRG can be used for fluorescence detection of diseases such as tumors and diabetic nephropathy .

HY-D1560

FG 488 DHPE	Fluorescent Dyes/Probes
FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well .

Cat. No.	Product Name	Type

HY-W011271

PIPES monosodium 1,4-Piperazinediethanesulfonic acid monosodium	Buffer Reagents
PIPES (1,4-Piperazinediethanesulfonic acid) monosodium is a pH buffer that can be mixed with another disodium salt form of PIPES. By changing the ratio and total amount of the PIPES monosodium and disodium buffers, the pH and ionic strength of the medium can be changed .

HY-W087928

Bromocresol purple	Indicators
Bromocresol purple is a pH indicator, whose color changes from yellow to purple when the pH increases from 5.2 to 6.8. Bromocresol purple can be used for detecting yeast cells with plasma membrane damage .

HY-D0227F

THAM hydrochloride (≥99%, reagent grade) 1 Publications Verification Tris HCl (≥99%, reagent grade); Tris hydrochloride (≥99%, reagent grade)	Buffer Reagents
THAM hydrochloride (≥99%, reagent grade), also known as Tris-HCl, is a buffer commonly used in various biochemical and molecular biology applications to maintain a stable pH environment. Tris-HCl has unique chemical properties that allow it to resist changes in pH when acidic or basic substances are added, which makes it useful for stabilizing biological samples or reagents. It is commonly used in electrophoresis and protein purification procedures.

THAM hydrochloride (≥99%, reagent grade)

1 Publications Verification

Tris HCl (≥99%, reagent grade); Tris hydrochloride (≥99%, reagent grade)

Buffer Reagents

THAM hydrochloride (≥99%, reagent grade), also known as Tris-HCl, is a buffer commonly used in various biochemical and molecular biology applications to maintain a stable pH environment. Tris-HCl has unique chemical properties that allow it to resist changes in pH when acidic or basic substances are added, which makes it useful for stabilizing biological samples or reagents. It is commonly used in electrophoresis and protein purification procedures.

HY-W110798

Bromophenol blue indicator (3.0-4.6)

Indicators

Bromophenol blue indicator (3.0-4.6) is a synthetic dye commonly used as an acid-base indicator with a transition range of pH 3.0-4.6. Bromophenol blue indicator (3.0-4.6) is water soluble and changes color from yellow to blue as the pH of the solution changes from acidic to basic. Its unique chemical properties make it an important ingredient in a variety of scientific applications, especially in biochemistry and molecular biology. In addition, it can be used as a stain in microbiology and histology. However, Bromophenol blue indicator (3.0-4.6) has potential irritating and staining properties.