Search Result

Results for "

PPm

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Autophagy (2) Bacterial (3) Cholinesterase (ChE) (2) ERK (1) Fluorescent Dye (1) Fungal (5) GABA Receptor (2) Glucosidase (1) Isotope-Labeled Compounds (1) Liposome (1) MDM-2/p53 (1) Mitochondrial Metabolism (1) NF-κB (1) NO Synthase (2) Parasite (5) Phosphatase (4) PPAR (1) PROTACs (1) Small Interfering RNA (siRNA) (11)
By Research Areas:	Cancer (8) Infection (17) Inflammation/Immunology (4) Metabolic Disease (4) Neurological Disease (1)
Oligonucleotides:	Pre-designed siRNA Sets (11) Cationic Lipids (1) siRNAs (11)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14817

Indeglitazar PPm 204	PPAR	Metabolic Disease
Indeglitazar (PPM 204) is an orally available PPAR pan-agonist for all three PPARα, PPARδ and PPARγ .

HY-164220

PPM1A-IN-1	Phosphatase Bacterial	Infection
PPM1A-IN-1 (Compound IV-4) is an inhibitor for PP2C Ser/Thr phosphatase protein phosphatase Mg2+/Mn2+-dependent 1A. PPM1A-IN-1 exhibits antibacterial activity against Mycobacterium tuberculosis .

HY-157218

*PPm*	Fungal	Inflammation/Immunology
PPm, a derivative of penthiopyrad and hapten, is a representative member of the succinate dehydrogenase inhibitors group of fungicides .

HY-149616

PPM-3	PROTACs ERK	Cancer
PPM-3 is a potent and selective PROTAC ERK5 degrader, with an IC₅₀ of 62.4 nM. PPM-3 did not influence tumor cell growth directly. PPM-3 influences tumor development by affecting the differentiation of macrophages .

HY-118160

PPM-18 NSC 73233	NO Synthase	Inflammation/Immunology Cancer
PPM-18 (NSC 73233), a potent anti-inflammatory agent, inhibits nitric oxide synthase expression. PPM-18 is a potent inhibitor of iNOS expression by blocking the binding of NF-κB to promoter . PPM-18, an analog of Vitamin K, induces autophagy and apoptosis in bladder cancer cells through ROS and AMPK signaling pathways .

HY-RS10960

PPM1A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1A Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1A Human Pre-designed siRNA Set A PPM1A Human Pre-designed siRNA Set A

HY-RS10969

PPM1L Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1L Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1L Human Pre-designed siRNA Set A PPM1L Human Pre-designed siRNA Set A

HY-RS10961

PPM1B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1B Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1B Human Pre-designed siRNA Set A PPM1B Human Pre-designed siRNA Set A

HY-RS10962

PPM1D Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1D Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1D Human Pre-designed siRNA Set A PPM1D Human Pre-designed siRNA Set A

HY-RS10963

PPM1E Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1E Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1E gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1E Human Pre-designed siRNA Set A PPM1E Human Pre-designed siRNA Set A

HY-RS10964

PPM1F Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1F Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1F gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1F Human Pre-designed siRNA Set A PPM1F Human Pre-designed siRNA Set A

HY-RS10965

PPM1G Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1G Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1G gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1G Human Pre-designed siRNA Set A PPM1G Human Pre-designed siRNA Set A

HY-RS10966

PPM1H Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1H Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1H gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1H Human Pre-designed siRNA Set A PPM1H Human Pre-designed siRNA Set A

HY-RS10967

PPM1J Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1J Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1J gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1J Human Pre-designed siRNA Set A PPM1J Human Pre-designed siRNA Set A

HY-RS10968

PPM1K Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1K Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1K gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1K Human Pre-designed siRNA Set A PPM1K Human Pre-designed siRNA Set A

HY-RS10970

PPM1M Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPM1M Human Pre-designed siRNA Set A contains three designed siRNAs for PPM1M gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPM1M Human Pre-designed siRNA Set A PPM1M Human Pre-designed siRNA Set A

HY-164537

SPI-001	Phosphatase MDM-2/p53 Apoptosis	Cancer
SPI-001 is a *PPM1D*-specific inhibitor (IC₅₀=0.48 μM) with anticancer activity. SPI-001 inhibits *PPM1D* phosphatase activity and increases p53 phosphorylation in *PPM1D*-overexpressing human breast cancer cells. In addition, SPI-001 inhibits cell proliferation by inducing apoptosis .

HY-N0531

Filixic acid ABA	Parasite	Infection
Filixic acid ABA is a molluscicidal agent against B. peregrina adult snails, with an LD₅₀ of 8.40 ppm. Filixic acid ABA shows 100% mortality of B. peregrina at 15 ppm .

HY-N12428

17-Hydroxyjolkinolide A Caudicifolin; Fischeriana A	Others	Others
17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) is an insect feeding inhibitor isolated from the roots of spurge. 17-Hydroxyjolkinolide A induces grain aversion in S. zeamais and T. castaneum adults, with EC₅₀s of 631.9 ppm and 656.5 ppm, respectively.

HY-N3156

Odoratone Dehydroodoratol	Others	Others
Odoratone (Dehydroodoratol) has insecticidal activity (LC₅₀: 154 ppm) .

HY-159521

HN252	Others	Others
HN252 is a potent *PPM1B* inhibitor (K_i= 0.52 µM) .

HY-W103488

Chloridazon	Others	Others
Chloridazon is a herbicide with an LD₅₀ value of 76.6 ppm at genotoxicity assay .

HY-123077

Norsanguinarine	Fungal	Infection
Norsanguinarine, an alkaloid, has antifungal activity against Alternaria brassicicola, Curvularia maculans at 1000 ppm .

HY-155373

Antioxidant agent-16	Others	Metabolic Disease
Antioxidant agent-16 (Product 2) has strong antioxidant activity with an IC₅₀ value of 6.93 ppm .

HY-119687

Bifenazate	GABA Receptor	Infection
Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm . Bifenazate is a positive allosteric modulator of GABA receptor .

HY-N7931

Regaloside A 1 Publications Verification	NO Synthase NF-κB	Inflammation/Immunology
Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity .

HY-157162

Insecticidal agent 5	Cholinesterase (ChE)	Others
Insecticidal agent 5 (compound 8) is an AChE-targeting insecticide with an LD50 of 27.65 ppm against the cotton leafworm Spodoptera littoralis .

HY-N8585

Neoprocurcumenol	Parasite	Infection
Neoprocurcumenol is a larvicidal compound that exerts significant toxicity on mosquito larvae with LC₅₀ and LC ₉₀ values of 13.69 and 23.92 ppm, respectively .

HY-125778

Cochlioquinone B	Others	Metabolic Disease
Cochlioquinone is a sesquiterpene metabolite originally isolated from C. miyabeanus. It is a phytotoxin that inhibits root growth of finger millet (E. coracana) and rice plants (O. sativa) by 59.9 and 51.7%, respectively, when used at a concentration of 100 ppm.2 Cochlioquinone B inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from bovine heart mitochondria.

HY-128430

Farnesyl acetate	Others	Infection
Farnesyl acetate is a sesquiterpene isolated from the leaves of Amomum gagnepainii. Farnesyl acetate has significant toxicity against red palm weevil larvae with a LD₅₀ of 7867 ppm .

HY-N12976

Oryzalexin E	Fungal	Infection
Oryzalexin E is a diterpene phytoalexin, and can be isolated from UV-irradiated rice leaves. Oryzalexin E inhibits spore germination of Pyricularia oryzae with the ED₅₀ of 62.5 ppm .

HY-N1924

Crassicauline A Crassicaulin A	Others	Neurological Disease
Crassicauline A (Crassicaulin A) is a bioactive alkaloid found in roots of Aconitum carmichaeli. Crassicauline A (Crassicaulin A) possesses feeding deterrent activity against T. castaneum adults with an EC₅₀ of 1134.5 ppm .

HY-155372

α-Glucosidase-IN-39	Glucosidase	Metabolic Disease
α-Glucosidase-IN-39 is a potent inhibitor of α-glucosidase enzyme with an IC₅₀ of 869.06 ppm. α-Glucosidase-IN-39 can used in study antidiabetic .

HY-B0860

Diuron	Others	Cancer
Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male and female mice by 73 and 27%, respectively.

HY-D2337

Quinophthalone	Fluorescent Dye	Inflammation/Immunology
Quinophthalone is a dye with distinctive greenish yellow color. Quinophthalone is used as coloring agents for various materials. Quinophthalone is a strong sensitizer in guinea pigs, and its threshold concentration for induction and challenge is 10 ppm .

HY-163782

SMIP-031	Autophagy Phosphatase	Infection
SMIP-031 is a potent and orally active *PPM1A* inhibitor with an IC₅₀ value of 180 nM. SMIP-031 induces autophagy. SMIP-031 inhibits Mycobacterium tuberculosis infect in mice .

HY-119687R

Bifenazate (Standard)	GABA Receptor	Infection
Bifenazate (Standard) is the analytical standard of Bifenazate. This product is intended for research and analytical applications. Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm . Bifenazate is a positive allosteric modulator of GABA receptor .

HY-15880

CCT007093 2 Publications Verification	Phosphatase Apoptosis Autophagy	Cancer
CCT007093 is an effective *protein phosphatase 1D (PPM1D Wip1)* inhibitor. Wip1 inhibition can activate the mTORC1 pathway and enhance hepatocyte proliferation after hepatectomy .

HY-119419S

Pirimicarb-d6	Cholinesterase (ChE) Parasite Isotope-Labeled Compounds	Others
Pirimicarb-d₆ is the deuterium labeled Diuron. Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male

HY-138149

2-epi-Abamectin epi-Avermectin B1a	Others	Infection
2-epi-Abamectin is a degradation product of Abamectin. It is toxic to the two-spotted spider mite in a contact assay with an LC50 value of 4 ppm, which is approximately 100-fold less potent than abamectin.

HY-137970

Spinosyn D aglycone A-83543D aglycone	Parasite	Infection
Spinosyn D aglycone is an aglycone form of the insecticide Spinosyn D (HY-125326). Unlike spinosyn D, spinosyn D aglycone is not lethal to H. virescens (tobacco budworm) neonate larvae (LC50=>64 ppm).

HY-N7916

(-)-Menthone	Others	Others
(-)-Menthone is a monoterpene component of the essential oil of maturing peppermint. (+)-Neomenthyl-β-d-glucoside is a metabolite of (-)-Menthone .Mortality of two biological forms of Anopheles stephensi(larvae) exposed to about 45 ppm* (-)-Menthone is 27.67% and 94.92%.*

HY-129990

Dios-Arg diTFA	Liposome	Cancer
Dios-Arg diTFA, a cationic lipid with an arginine-bearing headgroup, shows obvious double bond proton signals at around 5.2-5.3 ppm. Dios-Arg diTFA is used, coupled to DOPE, to bind siRNA and plasmid to for cationic LNPs for intracellular transport .

HY-146145

Metyltetraprole	Fungal Mitochondrial Metabolism	Infection
Metyltetraprole is a promising fungicide with EC₅₀ values of both 0.002 ppm against sensitive wild-type and G143A mutant of Zymoseptoria tritici. Metyltetraprole is effective against QoI (quinone outside inhibitor) resistant strains. Metyltetraprole inhibits the respiratory chain via complex III .

HY-B0860R

Diuron (Standard)	Others	Cancer
Diuron (Standard) is the analytical standard of Diuron. This product is intended for research and analytical applications. Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male and female mice by 73 and 27%, respectively.

HY-127131

Leucanicidin	Bacterial	Infection
Leucanicidin is a macrolide bacterial metabolite originally isolated from S. halstedii. It is toxic to L. separata fourth instar larvae when used at a concentration of 20 ppm and to H. contortus, T. colubriformis, and O. circumcincta larvae (LD₅₀s=0.23-0.42 μg/mL).

HY-162572

Bitipazone	Parasite	Infection
Bitipazone, diacetylbis(piperidinethyl)thiourea cysteine ??ester (I), has potent anticoccidial activity. Bitipazone showed significant efficacy and good tolerability in rabbits and turkeys, and in chronic toxicity tests, bitipazone was tolerated in turkeys at concentrations below 90 ppm in feed. Pharmacokinetic studies show that bitipazone is eliminated slowly from the blood and organs of these animal species .

HY-N7916R

(-)-Menthone (Standard)	Others	Others
(-)-Menthone (Standard) is the analytical standard of (-)-Menthone. This product is intended for research and analytical applications. (-)-Menthone is a monoterpene component of the essential oil of maturing peppermint. (+)-Neomenthyl-β-d-glucoside is a metabolite of (-)-Menthone .Mortality of two biological forms of Anopheles stephensi(larvae) exposed to about 45 ppm (-)-Menthone is 27.67% and 94.92%.

HY-133002

Methyl sterculate Sterculic acid methyl ester; Methyl Sterculate	Others	Infection
Sterculic acid methyl ester is an ester form of sterculic acid, which is an inhibitor of Δ9 desaturase. Sterculic acid methyl ester (0.75 mM) inhibits the growth of, and is toxic to, the bacteria R. opacus. It decreases the fatty acid content, increases the ratio of palmitate to other fatty acids, and decreases the levels of stearate and oleate in R. opacus when used at concentrations of 0.25 or 0.5 mM. Sterculic acid methyl ester (50 ppm) has a synergistic effect on increased tumor growth induced by aflatoxin Q1 in rainbow trout.

HY-N10653

Altemicidin (-)-Altemicidin	Others	Cancer
Altemicidin is a monoterpene alkaloid originally isolated from S. sioyaensis with acaricidal and anticancer activities. It is acaricidal to two-spotted spider mites (T. urticae) in a greenhouse pot test at concentrations of 10 and 100 ppm. Altemicidin inhibits the growth of murine L1210 lymphocytic leukemia and IMC carcinoma cells (IC₅₀s=0.84 and 0.82 μg/mL, respectively). It is toxic to mice with an LD₅₀ value of 0.3 mg/kg.

Cat. No.	Product Name

HY-L081

Phosphatase Inhibitor Library

117 compounds

Protein phosphorylation is a key post-translational modification underlying the regulation of many cellular processes. Phosphatases and kinases contribute to the regulation of protein phosphorylation homeostasis in the cell. This reversible regulation of protein phosphorylation is critical for the proper control of a wide range of cellular activities, including cell cycle, proliferation and differentiation, metabolism, cell-cell interactions, etc.

Protein phosphatases have evolved in separate families that are structurally and mechanistically distinct. Based on substrate specificity and functional diversity, protein phosphatases are classified into two superfamilies: Protein serine/threonine phosphatases and Protein tyrosine phosphatases. Ser/Thr phosphatases are metalloenzymes belonging to two major gene families termed PPP (phosphoprotein phosphatase) and PPM (metal-dependent protein phosphatases), whereas protein tyrosine phosphatases (PTPs) belong to distinct classes of enzymes that utilize a phospho-cysteine enzyme intermediate as a part of their catalytic action.

MCE supplies a unique collection of 117 phosphatase inhibitors that mainly targeting protein tyrosine phosphatases (PTPs) and serine/threonine-specific protein phosphatases. MCE Phosphatase Inhibitor Library is a useful tool for phosphatase drug discovery and related research.

Cat. No.	Product Name	Type

HY-D2337

Quinophthalone	Dyes
Quinophthalone is a dye with distinctive greenish yellow color. Quinophthalone is used as coloring agents for various materials. Quinophthalone is a strong sensitizer in guinea pigs, and its threshold concentration for induction and challenge is 10 ppm .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7931

Regaloside A 1 Publications Verification	Structural Classification Monophenols Liliaceae Classification of Application Fields Simple Phenylpropanols Source classification Phenols Phenylpropanoids Lilium regale Wilson Plants Inflammation/Immunology Disease Research Fields	NO Synthase NF-κB
Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity .

HY-N1924

Crassicauline A Crassicaulin A	Alkaloids Structural Classification Other Alkaloids Ranunculaceae Source classification Aconitum carmichaeli Debx. Plants	Others
Crassicauline A (Crassicaulin A) is a bioactive alkaloid found in roots of Aconitum carmichaeli. Crassicauline A (Crassicaulin A) possesses feeding deterrent activity against T. castaneum adults with an EC₅₀ of 1134.5 ppm .

HY-N0531

Filixic acid ABA	Infection Quinones Urticaceae Classification of Application Fields Debregeasia wallichiana (Wedd.) Wedd. Source classification Phenols Polyphenols Benzene Quinones Plants Disease Research Fields	Parasite
Filixic acid ABA is a molluscicidal agent against B. peregrina adult snails, with an LD₅₀ of 8.40 ppm. Filixic acid ABA shows 100% mortality of B. peregrina at 15 ppm .

HY-N12428

17-Hydroxyjolkinolide A Caudicifolin; Fischeriana A	Structural Classification Euphorbia fischeriana Steud. Terpenoids Source classification Diterpenoids Euphorbiaceae Plants	Others
17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) is an insect feeding inhibitor isolated from the roots of spurge. 17-Hydroxyjolkinolide A induces grain aversion in S. zeamais and T. castaneum adults, with EC₅₀s of 631.9 ppm and 656.5 ppm, respectively.

HY-N3156

Odoratone Dehydroodoratol	Triterpenes Structural Classification Terpenoids Toona sinensis (A. Juss.) Roem. Source classification Plants Meliaceae	Others
Odoratone (Dehydroodoratol) has insecticidal activity (LC₅₀: 154 ppm) .

HY-123077

Norsanguinarine	Infection Alkaloids Classification of Application Fields Source classification Plants Papaver somniferum Linn. Isoquinoline Alkaloids Disease Research Fields Papaveraceae	Fungal
Norsanguinarine, an alkaloid, has antifungal activity against Alternaria brassicicola, Curvularia maculans at 1000 ppm .

HY-N8585

Neoprocurcumenol	Structural Classification Natural Products Source classification Plants Curcuma aromatica Salisb. Zingiberaceae	Parasite
Neoprocurcumenol is a larvicidal compound that exerts significant toxicity on mosquito larvae with LC₅₀ and LC ₉₀ values of 13.69 and 23.92 ppm, respectively .

HY-125778

Cochlioquinone B	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Others
Cochlioquinone is a sesquiterpene metabolite originally isolated from C. miyabeanus. It is a phytotoxin that inhibits root growth of finger millet (E. coracana) and rice plants (O. sativa) by 59.9 and 51.7%, respectively, when used at a concentration of 100 ppm.2 Cochlioquinone B inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from bovine heart mitochondria.

HY-128430

Farnesyl acetate	Infection other families Classification of Application Fields Terpenoids Sesquiterpenes Source classification Plants Disease Research Fields	Others
Farnesyl acetate is a sesquiterpene isolated from the leaves of Amomum gagnepainii. Farnesyl acetate has significant toxicity against red palm weevil larvae with a LD₅₀ of 7867 ppm .

HY-N12976

Oryzalexin E	Structural Classification Natural Products Gramineae Source classification Oryza sativa L. Plants	Fungal
Oryzalexin E is a diterpene phytoalexin, and can be isolated from UV-irradiated rice leaves. Oryzalexin E inhibits spore germination of Pyricularia oryzae with the ED₅₀ of 62.5 ppm .

HY-N7916

(-)-Menthone	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Others
(-)-Menthone is a monoterpene component of the essential oil of maturing peppermint. (+)-Neomenthyl-β-d-glucoside is a metabolite of (-)-Menthone .Mortality of two biological forms of Anopheles stephensi(larvae) exposed to about 45 ppm* (-)-Menthone is 27.67% and 94.92%.*

HY-N7916R

(-)-Menthone (Standard)	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants	Others
(-)-Menthone (Standard) is the analytical standard of (-)-Menthone. This product is intended for research and analytical applications. (-)-Menthone is a monoterpene component of the essential oil of maturing peppermint. (+)-Neomenthyl-β-d-glucoside is a metabolite of (-)-Menthone .Mortality of two biological forms of Anopheles stephensi(larvae) exposed to about 45 ppm (-)-Menthone is 27.67% and 94.92%.

HY-114881

Frequentin NSC 246118	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Frequentin, a secondary metabolite produced by Penicillium janthinellum, is influenced by environmental conditions such as cadmium nitrate and sodium chloride concentrations. In cadmium nitrate-free medium, P. janthinellum produces cyclopenin, carlosic acid, erythroskyrin, kojic acid, and patulin. At 100 ppm cadmium nitrate, it produces cyclopenin, carlosic acid, frequentin, and islandicin. In the presence of sodium chloride, frequentin is produced at 2% and 3% concentrations. These findings indicate that frequentin production is sensitive to specific environmental stressors, highlighting its potential variability under different growth conditions .

HY-125048

Racemomycin B 229-B; Streptothricin D	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Racemomycin B (229-B; Streptothricin D), the main component from Streptomyces lavendulae OP-2, is a streptothricin antibiotic containing three β-lysine groups. RM-B exhibits antimicrobial activity against plant pathogenic microorganisms and effectively inhibits the growth of Brassica rapa L. roots at 50 ppm. RM-B showed a minimum inhibitory concentration (MIC) of 0.4 μg/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 μg/ml against six strains of Fusarium oxysporum, showing stronger antimicrobial activity than RM-A and RM-C. The biological activity of racemomycin compounds increases with the increase in the number of β-lysine groups.

Species:	Human (4) Mouse (1)
Tag:	His (3) GST (1)
Source:	HEK293 (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P701180

	PPM1H protein, Human (HEK293, His) Protein phosphatase 1H, PPm1H	Human	HEK293
	PPM1H, the enzyme subject, dephosphorylates CDKN1B at 'Thr-187,' critically regulating cellular processes. By preventing proteasomal degradation, PPM1H stabilizes CDKN1B, emphasizing its role in protein stabilization. This dephosphorylation event, orchestrated by PPM1H, intricately controls CDKN1B levels, showcasing its involvement in modulating cell cycle progression and regulating key cellular functions. PPM1H, Human (HEK293, His) is the recombinant human-derived PPM1H, expressed by HEK293 , with C-His labeled tag. The total length of PPM1H, Human (HEK293, His) is 514 a.a., with molecular weight of ~75 kDa.

HY-P71227

	PPM1A Protein, Human (His) Protein Phosphatase 1A; Protein Phosphatase 2C Isoform Alpha; PP2C-Alpha; Protein Phosphatase IA; PPm1A; PPPm1A	Human	E. coli
	PPM1A is a multifunctional enzyme that negatively regulates multiple signaling pathways. It significantly attenuates TGF-β signaling by dephosphorylating SMAD2 and SMAD3, leading to their dissociation from SMAD4, nuclear export, and signal termination. PPM1A Protein, Human (His) is the recombinant human-derived PPM1A protein, expressed by E. coli , with C-6*His labeled tag.

HY-P75979

	PPM1A Protein, Mouse (His) Protein Phosphatase 1A; Protein Phosphatase 2C Isoform Alpha; PP2C-Alpha; PPPm1A	Mouse	E. coli
	PPM1A is a multifunctional enzyme whose enzymatic activity exhibits broad specificity. It acts as a negative regulator of TGF-β signaling by dephosphorylating SMAD2 and SMAD3, leading to their dissociation from SMAD4, nuclear export of SMAD, and termination of TGF-β-mediated signaling. PPM1A Protein, Mouse (His) is the recombinant mouse-derived PPM1A protein, expressed by E. coli , with C-His labeled tag.

HY-P71022

	PP1MG Protein, Human (His) Protein Phosphatase 1G; Protein Phosphatase 1C; Protein Phosphatase 2C Isoform Gamma; PP2C-Gamma; Protein Phosphatase Magnesium-Dependent 1 Gamma; PPm1G; PPm1C	Human	E. coli
	PP1MG Protein, a member of PPM family of serine/threonine phosphatases, has an important role in controlling cell cycle progression. PP1MG Proteinregulates the phosphorylation of SRSF3 in hepatocellular carcinoma (HCC) and contributes to the proliferation, invasion, and metastasis of HCC. PP1MG Protein forms a distinct holoenzyme complex with the PP2A regulatory subunit B56δ. B56δ‐PPM1G dephosphorylates α‐catenin at serine 641, which is necessary for the appropriate assembly of adherens junctions and the prevention of aberrant cell migration. PP1MG Protein, Human (His) is the recombinant human-derived PP1MG protein, expressed by E. coli , with C-6*His labeled tag. The total length of PP1MG Protein, Human (His) is 230 a.a., with molecular weight of ~30.0 kDa.

HY-P703005

	PPM1F Protein, Human (GST) KIAA0015; POPX2; CaMKPase	Human	E. coli
	PPM1F Protein, Human (GST) is the recombinant human-derived PPM1F, expressed by E. coli , with GST labeled tag. ,

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure