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Succinate Dehydrogenase

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119976
    Boscalid

    		Fungal Infection
    Boscalid is an anti-fungal agent. Boscalid is a succinate dehydrogenase (SDH) inhibitor .
    Boscalid
  • HY-162776
    Succinate dehydrogenase-IN-3

    		Succinate Dehydrogenase Fungal Infection
    Succinate dehydrogenase-IN-3 (Ig) is an inhibitor of Succinate dehydrogenase (SDH). Succinate dehydrogenase-IN-3 has antifungal activity .
    Succinate dehydrogenase-IN-3
  • HY-173021
    Succinate dehydrogenase-IN-7

    		Succinate Dehydrogenase Fungal Infection
    Succinate dehydrogenase-IN-7 (Compound 2f) is a Succinate dehydrogenase inhibitor (IC50 = 2.51 μM). Succinate dehydrogenase-IN-7 has fungicidal activity .
    Succinate dehydrogenase-IN-7
  • HY-169972
    Succinate dehydrogenase-IN-5

    		Succinate Dehydrogenase Infection
    Succinate dehydrogenase-IN-5 (Compound M8) is the inhibitor for succinate dehydrogenase. Succinate dehydrogenase-IN-5 interfers with the energy metabolism and growth of fungi, inhibits Rhizoctonia solani, Sclerotinia sclerotiorum, Botrytis cinerea and Fusarium graminearum with EC50 < 0.3 μg/mL .
    Succinate dehydrogenase-IN-5
  • HY-169965
    Succinate dehydrogenase-IN-4

    		Succinate Dehydrogenase Infection
    Succinate dehydrogenase-IN-4 (Compound 4b) is the inhibitor for succinate dehydrogenase with an IC50 of 3.38 μM. Succinate dehydrogenase-IN-4 exhibits antifungal activity against Physalospora piricola and Colletotrichum orbiculare with EC50 of 16.33 μM and 18.06 μM .
    Succinate dehydrogenase-IN-4
  • HY-163890
    Succinate dehydrogenase-IN-2

    		Succinate Dehydrogenase Parasite Infection
    Succinate dehydrogenase-IN-2 (Compound 12x) is an inhibitor for succinate dehydrogenase (SDH) with an IC50 of 1.22 mg/L. Succinate dehydrogenase-IN-2 exhibits antifungal activity, that inhibits S. sclerotiorum, V. mali, G. graminis, R. solani and B. cinerea with EC50 of 0.52-3.42 mg/L .
    Succinate dehydrogenase-IN-2
  • HY-172363
    Succinate dehydrogenase-IN-6

    		Succinate Dehydrogenase Fungal Infection
    Succinate dehydrogenase-IN-6 (Compound E23) is the inhibitor for succinate dehydrogenase that inhibits SDH in Rhizoctonia solani with an IC50 of 11.76 μM. Succinate dehydrogenase-IN-6 disrupts fungal cell membrane, exhibits board-spectrum antifungal activity that inhibits R. solani, V. dahliae, A. solani and C. gloeosporioides with EC50s of 0.41, 0.27, 1.15, 0.27 μg/mL, respectively. Succinate dehydrogenase-IN-6 exhibits no significant toxicity in rice and zebrafish (LC50 > 12.5 μg/mL) .
    Succinate dehydrogenase-IN-6
  • HY-162648
    Succinate dehydrogenase-IN-1

    		Fungal Infection
    Succinate dehydrogenase-IN-1 (Compound 34) is an inhibitor for succinate dehydrogenase (SDH) with an IC50 of 0.94 μM and a KD of 22.4 μM. Succinate dehydrogenase-IN-1 exhibits antifungal activity against Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea, with EC50 of 0.04 μM, 1.13 μM, 1.61 μM and 1.21 μM, respectively .
    Succinate dehydrogenase-IN-1
  • HY-157218
    PPm

    		Fungal Inflammation/Immunology Cancer
    PPm, a derivative of penthiopyrad and hapten, is a representative member of the succinate dehydrogenase inhibitors group of fungicides .
    PPm
  • HY-119976R
    Boscalid (Standard)

    		Fungal Infection
    Boscalid (Standard) is the analytical standard of Boscalid. This product is intended for research and analytical applications. Boscalid is an anti-fungal agent. Boscalid is a succinate dehydrogenase (SDH) inhibitor .
    Boscalid (Standard)
  • HY-149601
    SDH-IN-8

    		Fungal Infection
    SDH-IN-8 (compound G40) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 27 nM for porcine SDH. SDH-IN-8 has fungicidal properties .
    SDH-IN-8
  • HY-149600
    SDH-IN-7

    		Fungal Infection
    SDH-IN-7 (compound G28) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 26 nM for porcine SDH. SDH-IN-7 has fungicidal properties .
    SDH-IN-7
  • HY-156270
    SDH-IN-9

    		Bacterial Infection
    SDH-IN-9 (compound Ip) is a potent inhibitor of Succinate Dehydrogenase. SDH-IN-9 shows fungicidal activity against Fusarium graminearum Schw with the EC50 of 0.93 μg/mL .
    SDH-IN-9
  • HY-148921
    SDH-IN-2

    		Fungal Infection
    SDH-IN-2 is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL. SDH-IN-2 is also an antifungal agent. SDH-IN-2 inhibits phytopathogenic fungia with average EC50 values of 3.82-9.81 μg/mL for all the fungi . SDH-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    SDH-IN-2
  • HY-170974
    SDH-IN-20

    		Fungal Infection
    SDH-IN-20 (compound A19) is an antifungal agent. SDH-IN-20 against Verticillium dahlia, R. solani with EC50s of less than 3.0 μg/mL, 2.87 μg/mL. SDH-IN-20 exerts its highly antifungal effects by acting as an effective succinate dehydrogenase (SDH) inhibitor with an IC50 of 29.33 μM. SDH-IN-20 adversely impacts the integrity of cell membranes and mycelial morphologies of R. solani .
    SDH-IN-20
  • HY-159481
    SDH-IN-17

    		Succinate Dehydrogenase Fungal Infection Inflammation/Immunology
    SDH-IN-17 (compound C32), a hydrazide-containing flavonol derivative, is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 8.42 μM. SDH-IN-17 can occupy the active site and form strong interactions with the key residues of SDH. SDH-IN-17 exhibits antifungal activity against Rhizoctonia solani (EC50=0.170 μg/mL). SDH-IN-17 disrupts the normal growth of hyphae by affecting the structural integrity of the cell membrane and cellular respiration. SDH-IN-17 has the potential for plant disease control research .
    SDH-IN-17
  • HY-N7114A
    Chloramphenicol succinate sodium
    1 Publications Verification

    		 Bacterial Antibiotic Infection Metabolic Disease
    Chloramphenicol succinate sodium is a proagent of Chloramphenicol, with Haemotoxicity. Chloramphenicol succinate is a competitive substrate and inhibitor of succinate dehydrogenase (SDH) that is the possible reason for its toxicity .
    Chloramphenicol succinate sodium
  • HY-N7114
    Chloramphenicol succinate

    		Antibiotic Bacterial Infection Metabolic Disease
    Chloramphenicol succinate is a proagent of Chloramphenicol, with Haemotoxicity. Chloramphenicol succinate also is an antibiotic. Chloramphenicol succinate is a competitive substrate and inhibitor of succinate dehydrogenase (SDH) that is the possible reason for its toxicity .
    Chloramphenicol succinate
  • HY-N7114AR
    Chloramphenicol succinate (sodium) (Standard)

    		Bacterial Antibiotic Infection Metabolic Disease
    Chloramphenicol succinate (sodium) (Standard) is the analytical standard of Chloramphenicol succinate (sodium). This product is intended for research and analytical applications. Chloramphenicol succinate sodium is a proagent of Chloramphenicol, with Haemotoxicity. Chloramphenicol succinate is a competitive substrate and inhibitor of succinate dehydrogenase (SDH) that is the possible reason for its toxicity .
    Chloramphenicol succinate (sodium) (Standard)
  • HY-139851
    Fungicide5

    		Fungal Infection
    Fungicide5 is a fungicide candidate targeting succinate dehydrogenase (Ki = 0.095 μM).
    Fungicide5
  • HY-149653
    SDH-IN-10

    		Fungal Infection
    SDH-IN-10 is a potent succinate dehydrogenase inhibitor (SDHI) with antifungal effects .
    SDH-IN-10
  • HY-139839
    Y12196

    		Fungal Infection
    Y12196 is a novel succinate dehydrogenase inhibitor (SDHI) which exhibits strong fungicidal activity against F. graminearum.
    Y12196
  • HY-119459
    Fluopyram
    1 Publications Verification

    		 Fungal Infection
    Fluopyram is a succinate dehydrogenase inhibitor fungicide, inhibits the growth of F. virguliforme isolates with mean EC50 of 3.35 µg/mL .
    Fluopyram
  • HY-133726
    Bixafen

    		Bacterial Infection
    Bixafen, a member of the pyrazole class of fungicides, serves as a broad-spectrum agent for controlling pathogens in cereal crops by functioning as a succinate dehydrogenase inhibitor.
    Bixafen
  • HY-124408
    Mepronil

    		Fungal Infection
    Mepronil, a compound belonging to the carboxyamine group of fungicides, has a particularly strong bactericidal effect on basidiomycete fungi. Mepronil acts as a single point inhibitor of the succinate ubiquinone reductase or succinate dehydrogenase complex. Mepronil can be used in the study of cross resistance and biological infection .
    Mepronil
  • HY-B2004
    Thifluzamide

    		Fungal Infection
    Thifluzamide, a broad-spectrum succinate dehydrogenase inhibitor (SDHI) fungicide, has been widely used in the controlling of a variety of fungal diseases in rice fields .
    Thifluzamide
  • HY-120183
    Harzianopyridone

    		Fungal Infection
    Harzianopyridone is a compound that can be isolated from Trichoderma harzianum. Harzianopyridone is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 80 nM. Harzianopyridone has antifungal, antibacterial, and herbicidal activities .
    Harzianopyridone
  • HY-114509
    Anilazine

    		Bacterial Infection Metabolic Disease
    Anilazine is a fungicide and inhibit the growth of Rhizobium sp. and E. coli. Anilazine inhibits glucose oxidation and succinate oxidation and also inhibits in vitro succinic dehydrogenase activity .
    Anilazine
  • HY-106371
    Siccanin

    		Antibiotic Fungal Infection
    Siccanin is a succinate dehydrogenase (SDH) inhibitor (IC50=0.9 μM) with species-selective activity. Siccanin also is a antibiotic against pathogenic fungi .
    Siccanin
  • HY-D0007
    Blue Tetrazolium

    Tetrazolium blue

    		 Fluorescent Dye Others
    Blue Tetrazolium (Tetrazolium blue), as a blue dye for microbial research, can be reduced into blue tetrazolium formazan (BTF). Blue Tetrazolium can be used to determine the activity of succinate dehydrogenase (SDH) in yeast strains, which has been reduced as a substrate. Use DMSO to extract BTF from cells, and test absorption spectrum of BTF. The BTF shows a wide wavelength range of 480-600 nm with maximal absorbance seen at 540 nm. Blue Tetrazolium, combines with succinate dehydrogenase (SDH) .
    Blue Tetrazolium
  • HY-145326
    Antibacterial agent 67

    		Fungal Others
    Antibacterial agent 67 (IC50 = 0.03 μM) has a great enzyme-inhibiting activity increase toward succinate dehydrogenase in comparison with fluxapyroxad (IC50 = 4.40 μM).
    Antibacterial agent 67
  • HY-Y1787
    Dimethyl malonate
    1 Publications Verification

    		 Apoptosis Neurological Disease
    Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .
    Dimethyl malonate
  • HY-162500
    Antifungal agent 99

    		Fungal Infection
    Antifungal agent 99 (Compound E1) is a fungal succinate dehydrogenase (SDH) inhibitor. Antifungal agent 99 reduces mycelial density and significantly increase the mitochondrial number in mycelia cytoplasm .
    Antifungal agent 99
  • HY-124408R
    Mepronil (Standard)

    		Fungal Infection
    Mepronil (Standard) is the analytical standard of Mepronil. This product is intended for research and analytical applications. Mepronil, a compound belonging to the carboxyamine group of fungicides, has a particularly strong bactericidal effect on basidiomycete fungi. Mepronil acts as a single point inhibitor of the succinate ubiquinone reductase or succinate dehydrogenase complex. Mepronil can be used in the study of cross resistance and biological infection .
    Mepronil (Standard)
  • HY-168470
    Antifungal agent 125

    		Fungal Infection
    Antifungal agent 125 (compound 4H) is a potent inhibitor of succinate dehydrogenase (SDH), with the IC50 of 3.59 μg/mL. Antifungal agent 125 exhibits fungicidal activity against Alternaria alternata .
    Antifungal agent 125
  • HY-155700
    SDH-IN-6

    		Fungal Infection
    SDH-IN-6 (compound 6i) is a potent succinate dehydrogenase (SDH) inhibitor. SDH-IN-6 has antifungal activity against Valsa mali with an EC50 value of 1.77 mg/L .
    SDH-IN-6
  • HY-119459R
    Fluopyram (Standard)

    		Fungal Infection
    Fluopyram (Standard) is the analytical standard of Fluopyram. This product is intended for research and analytical applications. Fluopyram is a succinate dehydrogenase inhibitor fungicide, inhibits the growth of F. virguliforme isolates with mean EC50 of 3.35 μg/mL .
    Fluopyram (Standard)
  • HY-108012
    ME1111

    		Fungal Infection
    ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research .
    ME1111
  • HY-133726R
    Bixafen (Standard)

    		Bacterial Infection
    Bixafen (Standard) is the analytical standard of Bixafen. This product is intended for research and analytical applications. Bixafen, a member of the pyrazole class of fungicides, serves as a broad-spectrum agent for controlling pathogens in cereal crops by functioning as a succinate dehydrogenase inhibitor.
    Bixafen (Standard)
  • HY-172362
    SDH-IN-22

    		Succinate Dehydrogenase Fungal Infection
    SDH-IN-22 (Compound SEZC7) is the inhibitor for succinate dehydrogenase (SDH) with an IC50 of 16.6 μM. SDH-IN-22 exhibits antifungal activity that inhibits Magnaporthe grisea with an EC50 of 0.5 mg/L .
    SDH-IN-22
  • HY-B2004R
    Thifluzamide (Standard)

    		Fungal Infection
    Thifluzamide (Standard) is the analytical standard of Thifluzamide. This product is intended for research and analytical applications. Thifluzamide, a broad-spectrum succinate dehydrogenase inhibitor (SDHI) fungicide, has been widely used in the controlling of a variety of fungal diseases in rice fields .
    Thifluzamide (Standard)
  • HY-135549
    Fluxapyroxad

    		Fungal Antibiotic Infection
    Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. It works by inhibiting succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species .
    Fluxapyroxad
  • HY-W007972R
    Methyl 3-methoxyacrylate (Standard)

    		Others Others
    Anilazine (Standard) is the analytical standard of Anilazine. This product is intended for research and analytical applications. Anilazine is a fungicide and inhibit the growth of Rhizobium sp. and E. coli. Anilazine inhibits glucose oxidation and succinate oxidation and also inhibits in vitro succinic dehydrogenase activity .
    Methyl 3-methoxyacrylate (Standard)
  • HY-W753375
    Fluindapyr

    		Fungal Succinate Dehydrogenase Infection
    Fluindapyr is a broad-spectrum pyrazolamide chiral fungicide of succinate dehydrogenase inhibitor (SDHIs) with broad bactericidal spectrum and good efficacy. Fluopimomide is effective against M. incognita in vitro and application of fuopimomide shows some growth promotion effect in cucumber .
    Fluindapyr
  • HY-114509R
    Anilazine (Standard)

    		Bacterial Infection Metabolic Disease
    Anilazine (Standard) is the analytical standard of Anilazine. This product is intended for research and analytical applications. Anilazine is a fungicide and inhibit the growth of Rhizobium sp. and E. coli. Anilazine inhibits glucose oxidation and succinate oxidation and also inhibits in vitro succinic dehydrogenase activity .
    Anilazine (Standard)
  • HY-19688B
    Sitamaquine tosylate

    WR 6026 tosylate

    		 Parasite Mitochondrial Metabolism Infection
    Sitamaquine (WR6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine tosylate inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine tosylate is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes .
    Sitamaquine tosylate
  • HY-19688A
    Sitamaquine hydrochloride

    WR 6026 hydrochloride

    		 Parasite Mitochondrial Metabolism Infection
    Sitamaquine (WR6026) hydrochloride, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine hydrochloride inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine hydrochloride is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes .
    Sitamaquine hydrochloride
  • HY-162458
    Antifungal agent 100

    		Fungal Infection Inflammation/Immunology
    Antifungal agent 100 (compound 3i) exhibits significant antifungal effects against S. sclerotiorum with an EC50 value of 0.33 mg/L. Antifungal agent 100 displays an IC50 of 0.63 mg/mL against the Succinate dehydrogenase (SDH) of S. sclerotiorum .
    Antifungal agent 100
  • HY-W012875
    3-Nitropropanoic acid
    1 Publications Verification

    β-Nitropropionic acid; Bovinocidin

    		 Bacterial Apoptosis Autophagy Infection Metabolic Disease
    3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis .
    3-Nitropropanoic acid
  • HY-155004
    SDH-IN-3

    		Antibiotic Fungal Infection
    SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 7.2 μg/mL. SDH-IN-3 exhibits excellent antifungal activities against Nigrospora oryzae with an EC50 of 1.9 μg/mL. SDH-IN-3 can be used for anti-infection research .
    SDH-IN-3

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