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Results for "

Tyr-Gly-Gly

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenylate Cyclase (2) Amino Acid Derivatives (4) Apoptosis (2) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (1) Caspase (2) Endogenous Metabolite (5) ERK (1) Fluorescent Dye (1) iGluR (2) Influenza Virus (1) Kallikrein (2) LDLR (3) Opioid Receptor (36) PD-1/PD-L1 (2) Peptide-Drug Conjugates (PDCs) (2) Potassium Channel (2) Ser/Thr Protease (2) Toll-like Receptor (TLR) (1) Transthyretin (TTR) (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (4) Endocrinology (1) Infection (1) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (37)

By Targets:

Adenylate Cyclase (2)

Amino Acid Derivatives (4)

Apoptosis (2)

Autophagy (1)

Bacterial (1)

Biochemical Assay Reagents (1)

Caspase (2)

Endogenous Metabolite (5)

ERK (1)

Fluorescent Dye (1)

iGluR (2)

Influenza Virus (1)

Kallikrein (2)

LDLR (3)

Opioid Receptor (36)

PD-1/PD-L1 (2)

Peptide-Drug Conjugates (PDCs) (2)

Potassium Channel (2)

Ser/Thr Protease (2)

Toll-like Receptor (TLR) (1)

Transthyretin (TTR) (1)

Wnt (1)

β-catenin (1)

By Research Areas:

Cancer (9)

Cardiovascular Disease (4)

Endocrinology (1)

Infection (1)

Inflammation/Immunology (4)

Metabolic Disease (1)

Neurological Disease (37)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P0073

Tyr-Gly-Gly-Phe-Met-OH 2 Publications Verification Met-Enkephalin; Methionine enkephalin; Metenkefalin	Opioid Receptor	Neurological Disease Cancer
Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.

HY-P1170

N-terminally acetylated Leu-enkephalin Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH	Opioid Receptor	Neurological Disease
N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

HY-P1742

Gluten Exorphin B5	Opioid Receptor	Metabolic Disease
Gluten Exorphin B5 is an exogenous opioid peptides derived from wheat gluten, acts on opioid receptor, increases postprandial plasma insulin level in rats .

HY-P0288

[Leu5]-Enkephalin 1 Publications Verification Leu-enkephalin; Leucine enkephalin; Leucyl-enkephalin	Opioid Receptor Endogenous Metabolite	Neurological Disease
[Leu5]-Enkephalin is a pentapeptide with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

HY-P1467A

[Met5]-Enkephalin, amide TFA 5-Methionine-enkephalin amide TFA	Opioid Receptor	Neurological Disease
[Met5]-Enkephalin, amide TFA is an agonist for δ opioid receptors as well as putative ζ ζ opioid receptors.

HY-P1470

[Leu5]-Enkephalin, amide Leu-Enkephalin amide	Opioid Receptor	Neurological Disease
[Leu5]-Enkephalin, amide is a δ opioid receptor agonist.

HY-P2676

Enkephalin(1-3) Tyr-Gly-Gly	Amino Acid Derivatives	Others
Enkephalin(1-3) (Tyr-Gly-Gly) is a tripeptide containing one L-tyrosine and two glycine residues .

HY-P3558

*Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met*	Amino Acid Derivatives	Others
Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met

HY-P0288A

[Leu5]-Enkephalin TFA	Opioid Receptor Endogenous Metabolite	Neurological Disease
[Leu5]-Enkephalin TFA is a pentapeptide with morphine like properties. [Leu5]-Enkephalin TFA is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

HY-P1467

[Met5]-Enkephalin, amide 5-Methionine-enkephalin amide	Opioid Receptor	Neurological Disease
[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ ζ opioid receptors.

HY-P4196

Met-Enkephalin-Arg-Phe	Opioid Receptor	Neurological Disease
Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity .

HY-P1863

α-Neoendorphin (1-8)	Opioid Receptor	Neurological Disease
α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin. α-Neoendorphin is an endogenous opioid peptide.

HY-P2159

Dynorphin A (1-8)	Opioid Receptor Endogenous Metabolite	Neurological Disease
Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC₅₀=303 nM) .

HY-P1087

Adrenorphin Metorphamide	Opioid Receptor	Cancer
Adrenorphin is a opioid octapeptide, acting as a potent agonist of μ-opioid receptor, with K_i of 12 nM.

HY-P5826

Dynorphin B (1-9)	Opioid Receptor	Neurological Disease
Dynorphin B (1-9) is a neuropeptide and N-terminal cleavage product of dynorphin B. The formation of dynorphin B (1-9) is blocked by N-ethylmaleimide (NEM), a non-selective inhibitor of cysteine peptidases .

HY-P10908

H-20	PD-1/PD-L1	Others
H-20 is a PD-1 agonist. H-20 can be used in the research of chronic pain .

HY-P1594

Dynorphin A (1-10)	Opioid Receptor iGluR	Neurological Disease
Dynorphin A (1-10) an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) also blocks NMDA-activated current with an IC₅₀ of 42.0 μM.

HY-P10615

Abz-YGGRASDQ-EDDnp	Fluorescent Dye Transthyretin (TTR)	Others
Abz-YGGRASDQ-EDDnp is a fluorescent substrate of transthyretin (TTR) protein and is used to detect the hydrolytic activity of TTR protein .

HY-P1594A

Dynorphin A (1-10) (TFA)	Opioid Receptor iGluR	Neurological Disease
Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) (TFA) also blocks NMDA-activated current with an IC₅₀ of 42.0 μM.

HY-P3647

[DPro10] Dynorphin A (1-11), porcine	Opioid Receptor Adenylate Cyclase	Neurological Disease
[DPro10] Dynorphin A (1-11), porcine, a N-Alkylated derivative, is a potent κ-opioid receptor agonist with a K_i value of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine has analgesic property .

HY-P3647A

[DPro10] Dynorphin A (1-11), porcine hydrochloride	Opioid Receptor Adenylate Cyclase	Neurological Disease
[DPro10] Dynorphin A (1-11), porcine hydrochloride, a N-Alkylated derivative, is a potent κ-opioid receptor agonist with a K_i value of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine hydrochloride has analgesic property .

HY-P1337

Dynorphin B (1-13)	Opioid Receptor	Neurological Disease
Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.

HY-P10421

PKCδ substrate	ERK	Cancer
PKCδ substrate acts as a nuclear transporter of ERK2 and is involved in ERK2 mediated gene activation. PKCδ is involved in the regulation of cell growth, proliferation, cell cycle arrest, and apoptosis by phosphorylating hBVR and other proteins. PKCδ substrate can be used to study the development of diseases, especially cancer biology .

HY-P0088

Porcine dynorphin A(1-13) Dynorphin A Porcine Fragment 1-13	Opioid Receptor	Others
Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations.

HY-P1337A

Dynorphin B (1-13) TFA	Opioid Receptor	Neurological Disease
Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor.

HY-P10217

PD-1/PD-L1-IN-42	PD-1/PD-L1	Cancer
PD-1/PD-L1-IN-42 (Compound B8.4) is an inhibitor of the interaction between PD-1 and PD-L1, with an EC₅₀ of 0.1 μM. PD-1/PD-L1-IN-42 can be used for the research of cancer immunotherapy .

HY-P5061

Dynorphin A (1-13) amide	Opioid Receptor	Neurological Disease
Dynorphin A (1-13) amide is an endogenous opioid peptide that antagonizes morphine-induced analgesia .

HY-P1625

Daeatal Dynorphin A ethylamide (1-9)	Opioid Receptor	Neurological Disease
Daeatal (Dynorphin A ethylamide (1-9)) is an ethylamine-modified dynorphin fragment that can be used in the study of analgesia, addiction, depression, etc. Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease .

HY-P1253

α-Endorphin (human)	Opioid Receptor	Neurological Disease
α-Endorphin (human) is a neuropeptide, that acts on the central nervous system (CNS) and peripheral nervous system (PNS). α-Endorphin (human) binds μ-opioid receptor, and exhibits analgesic efficacy. α-Endorphin (human) regulates sexual behaviors and pleasure felling .

HY-P1333

Dynorphin A	Opioid Receptor Apoptosis Caspase Endogenous Metabolite	Neurological Disease
Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease .

HY-P1333A

Dynorphin A TFA	Opioid Receptor Apoptosis Caspase Endogenous Metabolite	Neurological Disease
Dynorphin A TFA is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A TFA is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A TFA can induce neuronal death, and can be used in the research of neurological disease .

HY-P1819

N-Acetyl-α-Endorphin	Opioid Receptor	Neurological Disease
N-Acetyl-α-Endorphin is an acetylated α-Endorphin at N-terminal. α-Endorphin is an endogenous opioid peptide.

HY-P2341

Angiopep-2 hydrochloride 2 Publications Verification	LDLR	Cancer
Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer .

HY-P5907

Helianorphin-19	Opioid Receptor	Neurological Disease
Helianorphin-19 is a potent and selective κ-opioid receptor (KOR) activator with a K_i of 21 nM and an EC₅₀ of 45 nM. Helianorphin-19 exhibits strong KOR-specific peripheral analgesic activity in a mouse model of chronic visceral pain .

HY-P1351

Angiopep-2-Cys	Biochemical Assay Reagents	Cancer
Angiopep-2-cys is a conjugate of Angiopep-2 hydrochloride (HY-P2341) and cysteine. Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer .

HY-P4106A

Tat-GluR23Y, scrambled TFA 1 Publications Verification	Amino Acid Derivatives	Neurological Disease
Tat-GluR23Y, scrambled TFA is the scrambled peptide of Tat-GluR23Y (HY-P2259). Tat-GluR23Y is a synthetic peptide containing tyrosine residues that inhibit AMPAR endocytosis and is effective in the research of long-term depression (LTD) .

HY-P4106

Tat-GluR23Y, scrambled	Amino Acid Derivatives	Neurological Disease
Tat-GluR23Y, scrambled is the scrambled peptide of Tat-GluR23Y (HY-P2259). Tat-GluR23Y is a synthetic peptide containing tyrosine residues that inhibit AMPAR endocytosis and is effective in the research of long-term depression (LTD) .

HY-P10911

IETP2	LDLR	Others
IETP2 targets low-density lipoprotein receptor-related protein 1 (LRP1) with a K_D of 738 nM and can be used for drug- and imaging agents delivery across the blood-labyrinth barrier (BLB) .

HY-P1331

BAM-22P Bovine adrenal medulla-22P	Opioid Receptor	Neurological Disease
BAM-22P, a highly potent opioid peptide, is a potent opioid agonist.

HY-P4073

ANG1005 GRN1005; Paclitaxel trevatide	Peptide-Drug Conjugates (PDCs) LDLR	Cancer
ANG1005 (Paclitaxel trevatide) is a brain-penetrating peptide-drug conjugate. ANG1005, a taxane derivative, consists of three paclitaxel (HY-B0015) molecules covalently linked to Angiopep-2, designed to cross the blood-brain and blood-cerebrospinal barriers and to penetrate malignant cells via low density lipoprotein receptor-related protein (LRP1) transport system .

HY-P5117

TAT-CIRP	Toll-like Receptor (TLR)	Neurological Disease
TAT-CIRP is a a small peptide, refers to Trans-trans-activating (Tat)-cold-inducible RNA binding protein. TAT-CIRP is an inhibitor of myeloid differentiation protein 2 (MD2). TAT-CIRP exhibits robust neuroprotection against ischemic and hemorrhagic stroke in mice .

HY-P5892

β-Endorphin (1-27) (human)	Opioid Receptor	Neurological Disease
β-Endorphin (1-27) (human) is an opioid antagonist that binds μ-, δ-, and κ-opioid receptors with K_is of 5.31, 6.17, and 39.82 nM, respectively. β-Endorphin (1-27) (human) inhibits β-Endorphin (HY-P1502)-induced and etorphine-induced analgesia .

HY-P10006

Leumorphin, human	Opioid Receptor	Neurological Disease
Leumorphin, human is a potent kappa opioid receptor (κ opioid receptor) agonist. Leumorphin, human inhibits the contraction of the myenteric plexus-longitudinal muscle preparation of the guinea pig ileum .

HY-P10777

ANG1009	Peptide-Drug Conjugates (PDCs)	Cancer
ANG1009 is a BBB-penatrable anticancer agent. ANG1009 is cytotoxic to a variety of tumor cells and can induce cell cycle arrest. ANG1009 can be used in the study of brain cancer .

HY-P6441

KP-6	β-catenin Wnt	Inflammation/Immunology
KP-6, a polypeptide, is a Wnt/β-catenin signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD) .

HY-W019878

β-Endorphin, rat β-Lipotropin 61-91	Opioid Receptor	Cardiovascular Disease Neurological Disease
β-Endorphin, rat (β-Lipotropin 61-91), a neuropeptide, is involved in cardiovascular regulation. β-Endorphin, rat induces marked, prolonged muscular rigidity and immobility similar to a catatonic state in rats .

HY-P2046

β-Endorphin (rat)	Opioid Receptor	Neurological Disease
β-Endorphin (rat) is an endogenous opioid neuropeptide and peptide hormone. β-Endorphin (rat) has analgesic activity and also contributes to food intake in satiated rats. β-Endorphin (rat) can be used in the research of neurological diseases such as analgesia and drug addiction .

HY-P1502

β-Endorphin, human 1 Publications Verification	Opioid Receptor	Neurological Disease
β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus, is an agonist of opioid receptor, with preferred affinity for μ-opioid receptor and δ-opioid receptor; β-Endorphin, human exhibits antinociception activity.

HY-P1866A

β-Endorphin, equine TFA	Opioid Receptor	Neurological Disease
β-Endorphin, equine TFA is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors. β-Endorphin, equine TFA has analgesic properties .

HY-P1866

β-Endorphin, equine	Opioid Receptor	Neurological Disease
β-Endorphin, equine is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors . Analgesic properties .

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