2. Search Result
Search Result
Results for "

dilation

" in MedChemExpress (MCE) Product Catalog:

60

Inhibitors & Agonists

2

Biochemical Assay Reagents

2

Peptides

7

Natural
Products

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2112
    Valethamate bromide

    		mAChR Others
    Valethamate bromide is an ester and is a potent rapidly acting anticholinergic spasmolytic and musculotropic agent which accelerates labor by improving cervical dilation .
    Valethamate bromide
  • HY-B0321
    Tropicamide
    4 Publications Verification

    Ro 1-7683

    		 mAChR Neurological Disease
    Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. When used as an eye drop, Tropicamide causes short-term mydriasis (pupil dilation) and cycloplegia. Tropicamide can be used in the research of neurological diseases, such as epilepsy .
    Tropicamide
  • HY-B0642
    Isosorbide mononitrate
    4 Publications Verification

    Isosorbide-5-mononitrate

    		 Autophagy Endogenous Metabolite Apoptosis Cardiovascular Disease Cancer
    Isosorbide mononitrate (Isosorbide-5-mononitrate) is an orally active nitric acid compound used for angina pectoris by dilating blood vessels and lowering blood pressure. Isosorbide mononitrate increases the viability and proliferation of HUVECs by decreasing Apoptosis and elevated the expressions of vedf, kdrl, pdgfr in zebrafish embryos. Isosorbide mononitrate is promising for research of heart failure and coronary heart disease .
    Isosorbide mononitrate
  • HY-129706
    LY127210 free base

    		Others Cardiovascular Disease
    LY127210 (free base) is a potent vasodilator with antihypertensive effects that reduces pressure in chloralose-anesthetized spontaneously hypertensive rats primarily by direct arteriolar dilation and to a lesser extent by decreasing cardiac output. LY127210 (free base) reduces blood pressure, heart rate and left ventricular end-diastolic pressure in hypertensive rats by reducing vascular resistance .
    LY127210 free base
  • HY-106077
    Meteneprost

    U 46785

    		 Prostaglandin Receptor Others
    Meteneprost (U 46785) is a cervical dilator that stimulates uterine contractions and dilates the cervical canal.
    Meteneprost
  • HY-106077A
    Meteneprost potassium

    U 46785 potassium

    		 Prostaglandin Receptor Others
    Meteneprost (U 46785) potassium is a cervical dilator that stimulates uterine contractions and dilates the cervical canal.
    Meteneprost potassium
  • HY-160846
    HDAC6-IN-40

    		HDAC Cardiovascular Disease
    HDAC6-IN-40 (Compound I-6) is an inhibitor for HDAC6 with IC50 of 0.029 μM .
    HDAC6-IN-40
  • HY-160845
    HDAC6-IN-39

    		HDAC Cardiovascular Disease
    HDAC6-IN-39 (Compound I-132) is an inhibitor for HDAC6 with IC50 of 0.0096 μM .
    HDAC6-IN-39
  • HY-W714710
    Teopranitol

    KC-046

    		 Prostaglandin Receptor Cardiovascular Disease
    Teopranitol (KC-046), a coronary vasodilator with a rather selective venous dilatation, is used for the study of the acute myocardial ischemia .
    Teopranitol
  • HY-107037
    Tolmesoxide

    RX71107

    		 Vasopressin Receptor Angiotensin Receptor Adrenergic Receptor Cardiovascular Disease
    Tolmesoxide (RX71107) is a peripheral vascular dilator with blood pressure lowering activity. Tolmesoxide has shown direct vasodilation in the human forearm arterial bed and dorsal hand vein. Tolmesoxide can dose-dependently increase blood flow in the forearm and produce dilation during contraction of the dorsal hand veins. Tolmesoxide can be used to study high blood pressure and angina .
    Tolmesoxide
  • HY-B1098B
    Hydroxyamphetamine hydrochloride

    4-Hydroxyamphetamine hydrochloride

    		 Drug Derivative Neurological Disease
    Hydroxyamphetamine (4-Hydroxyamphetamine) hydrochloride is a sympathomimetic agent, stimulates the sympathetic nervous system. Hydroxyamphetamine hydrochloride can be used in eye drops to dilate the pupil .
    Hydroxyamphetamine hydrochloride
  • HY-B1098
    Hydroxyamphetamine

    4-Hydroxyamphetamine

    		 Drug Derivative Neurological Disease
    Hydroxyamphetamine (4-Hydroxyamphetamine) is a sympathomimetic agent, stimulates the sympathetic nervous system. Hydroxyamphetamine can be used in eye drops to dilate the pupil .
    Hydroxyamphetamine
  • HY-119750
    Budralazine

    		Others Cardiovascular Disease
    Budralazine is a vasodilator, which dilates the vascular smooth muscle and exhibits hypotensive efficacy. Budralazine inhibits the central sympathetic nerve and exhibits an anti-tachycardic effect .
    Budralazine
  • HY-B1098A
    Hydroxyamphetamine hydrobromide

    4-Hydroxyamphetamine hydrobromide

    		 Adrenergic Receptor Neurological Disease
    Hydroxyamphetamine (4-Hydroxyamphetamine) hydrobromide is a sympathomimetic agent, stimulates the sympathetic nervous system. Hydroxyamphetamine hydrobromide can be used in eye drops to dilate the pupil .
    Hydroxyamphetamine hydrobromide
  • HY-121185
    Hexoprenaline

    		Adrenergic Receptor Infection Inflammation/Immunology
    Hexoprenaline is an orally active and selective β-adrenergic receptor agonist that dilates the bronchi. Hexoprenaline can be used in the study of bronchospasm, including asthma, bronchitis, and emphysema .
    Hexoprenaline
  • HY-119544
    Ripisartan

    UP-2696

    		 Angiotensin Receptor Cardiovascular Disease
    Ripisartan (UP-2696) is an angiotensin II receptor antagonist. Ripisartan is orally available. Ripisartan binds to angiotensin II receptors, dilates blood vessels, and lowers blood pressure .
    Ripisartan
  • HY-145564A
    Emprumapimod hydrochloride

    PF-07265803 hydrochloride

    		 p38 MAPK Cardiovascular Disease Inflammation/Immunology
    Emprumapimod (PF-07265803) hydrochloride is an orally active and selective inhibitor of p38α MAPK. Emprumapimod hydrochloride can be used for the research of dilated cardiomyopathy and acute inflammatory pain .
    Emprumapimod hydrochloride
  • HY-W354753
    Homatropine hydrochloride

    		mAChR Others
    Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs .
    Homatropine hydrochloride
  • HY-101952
    Prostaglandin E2
    Maximum Cited Publications
    35 Publications Verification

    PGE2; Dinoprostone

    		 Organoid Prostaglandin Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology
    Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
    Prostaglandin E2
  • HY-B0642R
    Isosorbide mononitrate (Standard)

    		Autophagy Endogenous Metabolite Cardiovascular Disease Cancer
    Isosorbide mononitrate (Standard) is the analytical standard of Isosorbide mononitrate. This product is intended for research and analytical applications. Isosorbide mononitrate (Isosorbide-5-mononitrate) is a nitric acid compound used for angina pectoris by dilating blood vessels and lowering blood pressure.
    Isosorbide mononitrate (Standard)
  • HY-B0535R
    Ethambutol (Standard)

    		Bacterial Antibiotic Infection
    Homatropine (hydrochloride) (Standard) is the analytical standard of Homatropine (hydrochloride). This product is intended for research and analytical applications. Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs .
    Ethambutol (Standard)
  • HY-W354753R
    Homatropine (hydrochloride) (Standard)

    		mAChR Others
    Homatropine (hydrochloride) (Standard) is the analytical standard of Homatropine (hydrochloride). This product is intended for research and analytical applications. Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs .
    Homatropine (hydrochloride) (Standard)
  • HY-110116
    SD-2590 hydrochloride

    		MMP Cardiovascular Disease Inflammation/Immunology Cancer
    SD-2590 hydrochloride is a potent MMP inhibitor with IC50 values of ﹤0.1, ﹤0.1, 0.18, and 1.7 nM for MMP2, MMP13, MMP9, and MMP8, respectively. SD-2590 hydrochloride inhibits dilation of the left ventricle in rats .
    SD-2590 hydrochloride
  • HY-169333
    1,4-Dihydropyridine

    1,4-DHP

    		 Calcium Channel Cardiovascular Disease
    1,4-Dihydropyridine is an inhibitor for calcium channel, that blocks the L-type calcium channels, reduces the influx of calcium ions into cardiac and vascular smooth muscle cells, and thus reduces the contractility and heart rate of the heart, dilates blood vessels, and lowers blood pressure .
    1,4-Dihydropyridine
  • HY-112076
    Atropine methyl bromide

    Methylatropine bromide

    		 mAChR Neurological Disease
    Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine .
    Atropine methyl bromide
  • HY-B0321R
    Tropicamide (Standard)

    Ro 1-7683 (Standard)

    		 mAChR Neurological Disease
    Tropicamide (Standard) is the analytical standard of Tropicamide. This product is intended for research and analytical applications. Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. Tropicamide produces short acting mydriasis (dilation of the pupil) and cycloplegia when applied as eye drops .
    Tropicamide (Standard)
  • HY-112076A
    Atropine methyl nitrate

    Methylatropine nitrate; Atropine methyl nitrate

    		 mAChR Neurological Disease
    Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine .
    Atropine methyl nitrate
  • HY-B0321S
    Tropicamide-d3

    Ro 1-7683-d3

    		 mAChR Neurological Disease
    Tropicamide-d3 is the deuterium labeled Tropicamide[1]. Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. Tropicamide produces short acting mydriasis (dilation of the pupil) and cycloplegia when applied as eye drops[2][3].
    Tropicamide-d3
  • HY-N12777
    Coixenolide

    		Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    Coixenolide can be isolated from coix seeds, and exhibits anti-inflammatory, anti-tumor and pain-reducing activities. Coixenolide stimulates the lung, heart, striated and smooth muscles at low doses, while inhibits at high doses. Coixenolide dilates pulmonary veins and improves pulmonary blood circulation .
    Coixenolide
  • HY-P10279
    Anaritide

    Human atrial natriuretic factor (102–126)

    		 Natriuretic Peptide Receptor (NPR) Cardiovascular Disease Others
    Anaritide is a synthetic form of atrial natriuretic peptide (ANP) composed of 25 amino acids. Anaritide increases glomerular filtration rate by dilating into and contracting out the bulbar arterioles. Anaritide can be used to study the effects on patients with acute tubular necrosis, particularly in improving dialysis free survival .
    Anaritide
  • HY-117618
    KF-14124

    		Drug Derivative Cardiovascular Disease
    KF-14124, an orally active organic nitrate, a long-acting vasodilator with highly selective venous dilating action. KF-14124 is used in the study for angina pectoris. KF-14124 shows good oral inhibition of lysine-vasopressin induced coronary vasospasm with a potency .
    KF-14124
  • HY-150092
    8(S),9(R)-EET

    		Drug Metabolite Cardiovascular Disease
    8(S),9(R)-EET is an eicosanoid product of Arachidonic acid (AA; HY-109590) by cytochromes P450. 8(S),9(R)-EET dilates canine epicardial arterioles in a concentration-dependent manner with an EC50 value of 121 nM .
    8(S),9(R)-EET
  • HY-B0424R
    Nitrendipine (Standard)

    		Calcium Channel Autophagy Cardiovascular Disease
    Nitrendipine (Standard) is the analytical standard of Nitrendipine. This product is intended for research and analytical applications. Nitrendipine (BAY-E-5009), an analogue of Nifedipine (HY-B0284), is a dihydropyridine calcium channel blocker with vasodilator action. Nitrendipine has antihypertensive effect .
    Nitrendipine (Standard)
  • HY-B0424
    Nitrendipine
    1 Publications Verification

    BAY-E-5009

    		 Calcium Channel Autophagy Cardiovascular Disease
    Nitrendipine (BAY-E-5009), an analogue of Nifedipine (HY-B0284), is a dihydropyridine calcium channel blocker with vasodilator action. Nitrendipine has antihypertensive effect .
    Nitrendipine
  • HY-134221
    S-Nitroso-N-acetylcysteine

    		Adrenergic Receptor Reactive Oxygen Species Cardiovascular Disease
    S-Nitroso-N-acetylcysteine is a nitric oxide donor. S-Nitroso-N-acetylcysteine has a tissue vascular dilation effect, which can enhance liver microcirculation and effectively prevent ischemia-reperfusion injury in fatty liver. S-Nitroso-N-acetylcysteine can reduce liver fibrosis in rats with cirrhosis .
    S-Nitroso-N-acetylcysteine
  • HY-P2780A
    Cathepsin B, Human Liver

    		Apoptosis Cathepsin Pyroptosis Ferroptosis Autophagy Necroptosis Inflammation/Immunology Cancer
    Cathepsin B, Human Liver is a cysteine protease in liver and is involved in multiple kinds of programmed cell death (including apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death). Cathepsin B (CTSB) have been implicated in various ECM-related disorders, such as dilated cardiomyopathy, lung fibrosis, proteinuric renal disorders, cancer, and osteoporosis .
    Cathepsin B, Human Liver
  • HY-101952R
    Prostaglandin E2 (Standard)
    Maximum Cited Publications
    35 Publications Verification

    PGE2(Standard); Dinoprostone (Standard)

    		 Prostaglandin Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology
    Prostaglandin E2 (Standard) is the analytical standard of Prostaglandin E2. This product is intended for research and analytical applications. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
    Prostaglandin E2 (Standard)
  • HY-100418
    SKA-111

    		Potassium Channel Cardiovascular Disease
    SKA-111 is a selective activator of potassium phannel KCa 3.1 , evokes KCa 3.1 membrane hyperpolarization in porcine endothelial cell. SKA-111 is capable of improving Bradykinin (HY-P0206)-induced coronary dilations in the isolated rat heart and can be used for cardiovascular disease research .
    SKA-111
  • HY-129445
    SG-209

    		Potassium Channel Cardiovascular Disease
    SG-209 is a Nicorandil (HY-B0341) derivative that produces relaxation through potassium channel activation, while this action contributes to the vasodilating action of Nicorandil (HY-B0341) at higher concentrations. SG-209 dilates tracheal smooth muscle and increases tracheal blood flow in anesthetized dogs .
    SG-209
  • HY-114672
    MBCQ

    		Phosphodiesterase (PDE) Cardiovascular Disease
    MBCQ is a potent and selective cGMP-specific phosphodiesterase (PDE V; PDE5) inhibitor with an IC50 of 19 nM. MBCQ lacks inhibitory activity toward other PDE isozymes (all IC50s>100 μM). MBCQ dilates coronary arteries via specific inhibition of cGMP-PDE .
    MBCQ
  • HY-145564
    Emprumapimod

    PF-07265803

    		 p38 MAPK Cardiovascular Disease Inflammation/Immunology
    Emprumapimod (PF-07265803) is a potent, orally active and selective inhibitor of p38α MAPK directly inhibits LPS-induced IL-6 production from RPMI-8226 cell (IC50=100 pM). Emprumapimod can be used for the research of dilated cardiomyopathy and acute inflammatory pain .
    Emprumapimod
  • HY-101952S1
    Prostaglandin E2-d9

    PGE2-d9; Dinoprostone-d9

    		 Isotope-Labeled Compounds Prostaglandin Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology
    Prostaglandin E2-d9 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation[1][2].
    Prostaglandin E2-d9
  • HY-101952S
    Prostaglandin E2-d4

    PGE2-d4; Dinoprostone-d4

    		 Prostaglandin Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology
    Prostaglandin E2-d4 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation[1][2].
    Prostaglandin E2-d4
  • HY-14252A
    Milrinone lactate

    Win 47203 lactate

    		 Phosphodiesterase (PDE) Cardiovascular Disease
    Milrinone lactate is a potent inotropic dilating agent. Milrinone lactate shows simultaneous positive inotropic and vasodilating activities. Milrinone lactate promotes reduction of SVR and PVR in patients with DCM and NYHA class III and IV of heart failure. Milrinone lactate has the potential for the research of cardiovascular function after cardiac surgery and in septic shock .
    Milrinone lactate
  • HY-14915A
    Bedoradrine sulfate

    MN-221; KUR-1246

    		 Adrenergic Receptor Inflammation/Immunology
    Bedoradrine (MN-221) sulfate is a highly selective β2-adrenergic receptor agonist. Bedoradrine sulfate can effectively relieve airway spasm in asthma patients, dilate airway smooth muscle cells, reduce airway inflammation, and thus improve respiratory function. Bedoradrine sulfate can be used in research on asthma treatment .
    Bedoradrine sulfate
  • HY-156242
    BQZ-485

    		Paraptosis Cancer
    BQZ-485 is a a potent GDI2 inhibitor through the interaction with Tyr245. BQZ-485 disrupts the intrinsic GDI2-Rab1A interaction, thereby abolishing vesicular transport from the endoplasmic reticulum (ER) to the Golgi apparatus and initiating subsequent paraptosis events .
    BQZ-485
  • HY-112076R
    Atropine methyl (bromide) (Standard)

    		mAChR Neurological Disease
    Atropine methyl (bromide) (Standard) is the analytical standard of Atropine methyl (bromide). This product is intended for research and analytical applications. Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine .
    Atropine methyl (bromide) (Standard)
  • HY-155475
    mTORC1-IN-2

    		mTOR Cardiovascular Disease
    mTORC1-IN-2 (compound H3) is a NO donor compound that alleviates vasodilation and attenuates myocardial hypoxic injury. mTORC1-IN-2 upregulates TSC2-P expression and inhibits mTORC1 expression .
    mTORC1-IN-2
  • HY-117181
    UK-1745

    		Phosphodiesterase (PDE) Adrenergic Receptor Cardiovascular Disease
    UK-1745 is a cardiotonic agent with vasodilating and antiarrhythmic properties. It increases intracellular levels of cyclic adenosine monophosphate (cAMP) in cardiomyocytes by inhibiting phosphodiesterase III, thereby enhancing myocardial contractility. Additionally, UK-1745 exhibits β-adrenergic receptor blocking activity, which helps reduce the oxygen consumption of the heart and prevent calcium overload. These characteristics make UK-1745 a promising candidate for research in congestive heart failure .
    UK-1745
  • HY-17402
    Nisoldipine
    1 Publications Verification

    BAY-k 5552

    		 Calcium Channel Reactive Oxygen Species Infection Cardiovascular Disease Neurological Disease
    Nisoldipine (BAY-k 5552; Sular) is an orally active and blood-brain barrier-penetrating dihydropyridine calcium antagonist, with greater vascular selectivity than other calcium channel antagonists. Nisoldipine inhibits calcium influx and blocks voltage-gated calcium channels. Nisoldipine dilates coronary and systemic arteries. Nisoldipine has antihypertensive and anti-anginal activity. Nisoldipine also displays neuroprotective and antiviral activity .
    Nisoldipine

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: