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Results for "

fluorophore

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Amino Acid Derivatives (1) Amyloid-β (1) Apoptosis (4) Autophagy (3) Biochemical Assay Reagents (1) Caspase (2) DNA Stain (4) Endothelin Receptor (1) Factor Xa (3) Fluorescent Dye (102) Ligands for Target Protein for PROTAC (1) Liposome (4) mAChR (1) MMP (1) PARP (1) Poly(ADP-ribose) Glycohydrolase (PARG) (2) Protease Activated Receptor (PAR) (1) Raf (1) Reactive Oxygen Species (2) SGLT (1)
By Research Areas:	Cancer (26) Cardiovascular Disease (4) Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (1)
Click Chemistry:	Labeling and Fluorescence Imaging (6) DBCO (4) BCN (1) Tetrazine (2) Alkynes (3)
Oligonucleotides:	Fluorescent Lipids (5) Pegylated Lipids (5) Aptamers (7) Cationic Lipids (1)

133

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0078

DCIA	Fluorescent Dye	Others
DCIA is a fluorescent dye. DCIA contains a coumarin fluorophore and conjugates specifically with free cysteines in the protein .

HY-W017873

9-Fluorenylmethyl carbazate	Fluorescent Dye	Others
9-Fluorenylmethyl carbazate is used as a fluorophore reagent for a fluorimetric detection of glycans .

HY-134566

NBD-X, SE	Fluorescent Dye	Others
NBD-X, SE, the acceptor fluorophore, can be used to create environment sensitive bioconjugates .

HY-124409

WSP-1	Fluorescent Dye	Others
WSP-1 is a selective and rapid-reaction H₂S specific fluorescent dye (Ex/Em=465/515 nm). WSP-1 reacts with H₂S with the releasing of fluorophore .

HY-D0074

Prodan	Fluorescent Dye	Others
Prodan, a solvatochromic fluorophore, has been used as a microenvironment-sensitive membrane reporter. Based on the chemistry of Prodan, fluorescent nucleosides are designed and synthesized.The fluorescent nucleosides sensitively varied the Stokes shift values depending on the orientational polarizability of the solvent .

HY-D2095

*Medical fluorophore* 33**	Fluorescent Dye	Cancer
Medical fluorophore 33 is a novel quinoline-isoquinoline salt. Medical fluorophore 33 exhibits a strong fluorescent signal, good microsomal stability and high biocompatibility in vivo. Medical fluorophore 33 has antitumor activity in colorectal cancer mice .

HY-142523

H7	Fluorescent Dye	Cancer
H7 is a second near-infrared (NIR-II) fluorophore .

HY-148796

Rizedisben GE3126	Fluorescent Dye	Others
Rizedisben (GE3126) is a fluorophore that can be used in fluorescence image-guided surgery. Rizedisben reduces non-specific adipose tissue fluorescence intensity and enhances nerve visibility .

HY-D1592

BODIPY TMR C5-maleimide	Fluorescent Dye	Others
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .

HY-P4138

Antennapedia Peptide FAM-labeled	Fluorescent Dye	Cancer
Antennapedia Peptide FAM-labeled is a fluorophore labeled peptide. Antennapedia Peptide FAM-labeled also can be used for the research of cancer as a molecular probe .

HY-W040291

7-Hydroxy-4-methylcoumarin-3-acetic acid, SE	Fluorescent Dye	Cancer
7-Hydroxy-4-methylcoumarin-3-acetic acid, SE is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. It is widely used for preparing bioconjugates of blue fluorescence.

HY-D2227

IR-58	Autophagy Apoptosis	Cancer
IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .

HY-D2219

Sulfo-Cy7 tetrazine	Fluorescent Dye	Others
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .

HY-111661

6,7-Dimethyl-8-ribityllumazine	Others	Others
6,7-Dimethyl-8-ribityllumazine is a direct biosynthetic precursor of Riboflavin (RBF; HY-B0456). 6,7-Dimethyl-8-ribityllumazine is a noncovalently bound fluorophore of Lumazine protein (LumP), which is a fluorescent accessory protein .

HY-D1651

BDP 630/650 amine	Fluorescent Dye	Others
BDP 630/650 amine is a far-red luminescent, boron-dipyridyl fluorophore. BDP 630/650 amine can label various electron-loving compounds. (λ_ex=630 nm, λ_em=650 nm).

HY-D2183

6-Carboxy-JF5252	Fluorescent Dye	Others
6-Carboxy-JF5252 is a fluorophore. 6-Carboxy-JF5252 can be used as probes, dyes, tags. 6-Carboxy-JF5252 can be used for the research of super-resolution imaging .

HY-D1464

CH1055 1 Publications Verification	Fluorescent Dye	Cancer
CH1055 is a NIR-II fluorophore based on a synthetic 970-Da organic molecule. CH1055 is a rapidly excreted dye (∼90% excreted through the kidneys within 24 h). CH1055 also allows targeted molecular imaging of tumors in vivo when conjugated with anti-EGFR Affibody .

HY-D1338

Cyanine3.5 carboxylic acid chloride Cyanine 3.5 carboxylic acid chloride; Lumiprobe Cy 3.5 carboxylic acid chloride	Fluorescent Dye	Others
Cyanine3.5 carboxylic acid chloride is an anthocyanin dye. Cyanine3.5 carboxylic acid chloride is Cyanine3.5 free unactivated monofunctional carboxylic acid and can be used as a reference or control for non-reactive dye. Cyanine3.5 also is an analog of Cy3.5 fluorophore .

HY-151712

Sulfo-Cy5-Methyltetrazine	Fluorescent Dye	Others
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

HY-D1464A

CH1055 triethylamine 1 Publications Verification	Fluorescent Dye	Cancer
CH1055 triethylamine is a NIR-II fluorophore based on a synthetic 970-Da organic molecule. CH1055 triethylamine is a rapidly excreted dye (∼90% excreted through the kidneys within 24 h). CH1055 triethylamine also allows targeted molecular imaging of tumors in vivo when conjugated with anti-EGFR Affibody .

HY-D2171

AF488 DBCO	Fluorescent Dye	Others
AF488 DBCO is a fluorescent dye that labels azide-containing biomolecules. DBCO is the bioorthogonal partner of azide that allows covalent coupling in the absence of copper. AF488 is a bright, photostable green fluorophore. AF488 exhibits the λ_em and λ_ex wavelength of 520 nm and 470 nm, respectively .

HY-D0208

Fluorescein sodium 3 Publications Verification Uranine sodium	Fluorescent Dye	Cancer
Fluorescein (Uranine) sodium is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) sodium is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes .

HY-W089353

8-Phenyl-BODIPY 505/515	Fluorescent Dye	Others
8-Phenyl-BODIPY 505/515, a phenyl-substituted BODIPY derivative, is a fluorophore, 8-Phenyl-BODIPY 505/515 can be used as fluorescent probe .

HY-D1590

BODIPY Green 8-P2M	Fluorescent Dye	Others
ODIPY Green 8-P2M is a novel thiol-reactive fluorescence probe based on the BODIPY fluorophore, the fluorescence is strongly quenched by d-PeT and then can be restored after reaction with thiol, resulting in an extremely high signal-to-noise ratio. ODIPY Green 8-P2M can be useful for detecting extremely low concentrations of protein in the gel after SDS-PAGE .

HY-W010947

4-Methylumbelliferyl palmitate	Fluorescent Dye	Inflammation/Immunology
4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions .

HY-151756

diSulfo-Cy3 alkyne	Fluorescent Dye	Others
diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an alkyne group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase .

HY-112526

Thiofluor 623	Fluorescent Dye	Others
Thiofluor 623 (Compound 3) is a fluorescent turn-on probe that can be used for the selective sensing and bioimaging of thiols. Thiofluor 623 displays excellent immunity to interference from nitrogen and oxygen nucleophiles. Thiofluor 623 is essentially nonfluorescent in the absence of thiols, which cleave the probe and release the red-emissive donor-acceptor fluorophore (Ex=563 nm, Em=623 nm) .

HY-151720

Cy5.5 DBCO	ADC Linker	Others
Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .

HY-D1596

Cyanine 3.5 chloride Cy3.5 NHS ester chloride; Cy 3.5 chloride	Fluorescent Dye	Others
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-D1363

BDP R6G maleimide	Fluorescent Dye	Others
BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .

HY-W073524

DFAME	Fluorescent Dye	Cancer
DFAME is a red fluorophore (Ex=508 nm, Em=641 nm). Beetroot and Corn are dimeric fluorogenic RNA aptamers that can bind to DFAME to form Beetroot-DFAME (K_d=460nM) and Corn-DFAME (K_d= 3600nM). Beetroot-DFAME (Kd=460nM) and Corn-DFAME can be used to form RNA assemblies in living cells. Creating RNA assemblies can be used for the study of RNA Nanostructures. DNA/RNA Nanostructures would be useful in cell and gene therapy (CGT) research .

HY-D1554

Cyanine5 tetrazine	Fluorescent Dye	Others
Cyanine5 tetrazine, a *fluorophore, is a molecule that contains a cyano5 fluorophore* and a tetrazine moiety .

HY-D1650

BDP 630/650 carboxylic acid	Fluorescent Dye	Others
BDP 630/650 carboxylic acid is a bright far-red fluorophore based on a borondipyrromethene scaffold. BDP 630/650 carboxylic acid is a BDP linker containing carboxylic acid. BDP 630/650 carboxylic acid can react with primary amine groups to form a stable amide bond. (λ_ex=630 nm, λ_em=650 nm) .

HY-103467

NPE-caged-HPTS sodium	Fluorescent Dye	Others
NPE-caged-HPTS sodium is a caged fluorophore that fluoresces upon uncaged fluorophore release, releasing the free highly polar fluorophore HPTS (Exc=470/40 nm, Em=525/50 nm). HPTS releases the fluorophore rapidly and uniformly, allowing for measurement of diffusion within tissues, with a diffusion coefficient of μm ²s ^?1, similar to that of synaptic L-glutamate .

HY-151728

Trisulfo-Cy3-Alkyne	Fluorescent Dye	Others
Trisulfo-Cy3-Alkyne is a water soluble cyanine linker containing an alkyne group, which enables Click Chemistry to attach trisulfo-Cy3 to various azide-bearing molecules. Trisulfo-Cyanine3 is a fluorophore which is compatible with a wide range of fluorescent scanners, imagers, microscopes, etc. It is a bright and photostable dye and can be easily detected in gels by naked eye in low amounts (nmol). Reagent grade, for research use only . Trisulfo-Cy3-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1560

FG 488 DHPE	Fluorescent Dye	Others
FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well .

HY-137791

MMBC	Fluorescent Dye	Others
MMBC is a sulfhydryl-sensitive fluorophore .

HY-112797

Ds-HAPP	Fluorescent Dye	Others
Ds-HAPP is an anthrancenyl and dansyl fluorophore ligand.

HY-D1349

Bodipy TR alkyne	Fluorescent Dye
Bodipy TR alkyneis one of a boron dipyrromethene fluorophore for the ROX (Texas Red) channel. This is a versatile fluorophore that can be used in microscopy, fluorescence polarization measurements, and other applications. This derivative is a terminal alkyne of copper-catalyzed click chemistry.

HY-D1659

BDP 581/591 alkyne	Fluorescent Dye	Others
BDP 581/591 alkyne is a moderately hydrophobic borondipyrromethene fluorophore.

HY-W440911

DSPE-PEG-Cy5, MW 2000	Liposome	Others
DSPE-PEG-Cy5, MW 2000 a red fluorophore polyPEG with lipid hydrophobic tails. The Cy5 fluorophore is commonly used in applications such as protein and nucleic acid labeling for imaging, flow cytometry, and genomic applications. The dye has an excitation peak at 651 nm and an emission peak at 670 nm.

HY-133532

PB succiniMidyl ester Ocean Blue, SE	Fluorescent Dye	Others
PB succiniMidyl ester (Ocean Blue, SE) is a fluorophore with the λ_{excitation/emission} of ~405/455 nm .

HY-W440908

DSPE-PEG-Cy3, MW 2000	Liposome	Others
DSPE-PEG-Cy3, MW 2000 is a fluorophore attached PEG lipid. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The dye has an absorption wavelength that peaks around 548-552 nm, and an emission maximum around 562-570 nm.

HY-103594

2-Aminoacridone	Fluorescent Dye	Others
2-Aminoacridone is a widely used fluorophore (λ_exc=428 nm, λ_em=525 nm).

HY-18675

IQ-R	Fluorescent Dye	Others
IQ-R is a novel hypoxia-sensitive fluorescent probe, consisting of an indolequinone unit and a rhodol fluorophore.

HY-D1268

Seph-PAO	Fluorescent Dye	Cancer
Seph-PAO is the modified PAO attached a sepharose fluorophore and is used to detect the thioredoxin reductase (TrxR) .

HY-W142395

6-TAMRA free acid	DNA Stain	Others
6-TAMRA free acid is a fluorophore widely used in the preparation of fluorescent antibodies and avidin derivatives for immunohistochemistry.

HY-D1564

Cy7.5 hydrazide	Fluorescent Dye	Others
Cy7.5 hydrazide is a fluorophore Cy7.5-labeled hydrazide fluorescent dye.

HY-D2292

BODIPY TMR acid	Fluorescent Dye	Cancer
BODIPY TMR acid is a fluorescent dye. BODIPY TMR acid is a high quantum yield fluorophore which can be coupled with Rebastinib .

HY-147177

Bodipy 8-chloromethane	Fluorescent Dye	Others
BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe .

Cat. No.	Product Name	Type

HY-143702

Fluorescent DOTAP NBD-DOTAP	Drug Delivery
Fluorescent DOTAP, a cationic lipid, can be used for the research of nucleic acid and protein delivery . Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm).

HY-W440911

DSPE-PEG-Cy5, MW 2000	Drug Delivery
DSPE-PEG-Cy5, MW 2000 a red fluorophore polyPEG with lipid hydrophobic tails. The Cy5 fluorophore is commonly used in applications such as protein and nucleic acid labeling for imaging, flow cytometry, and genomic applications. The dye has an excitation peak at 651 nm and an emission peak at 670 nm.

HY-W440908

DSPE-PEG-Cy3, MW 2000	Drug Delivery
DSPE-PEG-Cy3, MW 2000 is a fluorophore attached PEG lipid. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The dye has an absorption wavelength that peaks around 548-552 nm, and an emission maximum around 562-570 nm.

HY-160257

DOPE-PEG-BDP FL,MW 5000	Drug Delivery
DOPE-PEG-BDP FL,MW 5000 is a PEG-lipid-dye conjugate consists of a DOPE phospholipid which is an unsaturated phospholipid, a BDP FL fluorophore with featuring excitation and emission maxima at 504 and 514 nm respectively and a large PEG spacer which links the former substance together.

Cat. No.	Product Name	Target	Research Area

HY-P1986

Z-DEVD-AFC	Caspase	Cancer
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .

HY-P4138

Antennapedia Peptide FAM-labeled	Fluorescent Dye	Cancer
Antennapedia Peptide FAM-labeled is a fluorophore labeled peptide. Antennapedia Peptide FAM-labeled also can be used for the research of cancer as a molecular probe .

HY-P5373

Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2	Peptides	Others
Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)

HY-P2496

*Endothelin 1 (swine, human), Alexa Fluor* 488-labeled**	Endothelin Receptor	Cardiovascular Disease
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ET_A and ET_B .

HY-P5372

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2	Protease Activated Receptor (PAR)	Others
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biological active peptide. (Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This peptide is a PAR-1 selective agonist displaying a high level of specificity to PAR-1 over PAR-2. The specificity of peptide was evaluated in cell-based calcium signaling assay using HEK293 cells. PAR-1 selective agonists can be used to study PAR-1 activation in vivo. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.)

HY-P3430

JM3A	Peptides	Cancer
JM3A is a highly specific peptoid reagent that targets newly appears cell surface vimentin (CSV) on tumor-transformed early lung cancer cells. JM3A can detect and stain CSV by coupling with fluorophores .

HY-P5296

Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans	Fluorescent Dye	Others
Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans is a fluorophore Dabsyl-labeled peptide. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans can be used to test the peptidase activity of the LasA protease of Pseudomonas aeruginosa. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans has enzyme specificity and has application value .

HY-P2089

Dnp-PYAYWMR	MMP	Others
Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm .

HY-P2651

Dansyl-D-Ala-Gly-Phe(pNO2)-Gly	Fluorescent Dye	Others
Dansyl-D-Ala-Gly-Phe(pNO2)-Gly is a synthetic peptide substrate. As a substrate of NEP, Dansyl-D-Ala-Gly-Phe(pNO2)-Gly can be specifically recognized and cleaved by the enzyme, thereby releasing the fluorophore dansyl, which can be quantitatively detected. Therefore, it is often used to determine the activity of NEP .

HY-W072147

Fmoc-Ser-OMe Fmoc-L-Ser-OMe	Amino Acid Derivatives	Others
Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor .

HY-P10322

Z-IETD-R110	Fluorescent Dye	Cancer
Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .

HY-P3432

DfTat	Peptides	Others
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .

HY-P6023

D-Leu-Pro-Arg-Rh110-D-Pro	Factor Xa	Cardiovascular Disease
D-Leu-Pro-Arg-Rh110-D-Pro is a substrate for Factor Xa I (FXIa) with binding affinity. D-Leu-Pro-Arg-Rh110-D-Pro consists of Rhodamine 110 (HY-D0817) linked to a peptide chain through a cleavable bond. Cleavable bond cleavage enhances fluorophore intensity. D-Leu-Pro-Arg-Rh110-D-Pro can be used to detect FXIa activity .

HY-P6023B

D-Leu-Pro-Arg-Rh110-D-Pro acetate	Factor Xa	Cardiovascular Disease
D-Leu-Pro-Arg-Rh110-D-Pro acetate is a substrate for Factor Xa I (FXIa) with binding affinity. D-Leu-Pro-Arg-Rh110-D-Pro acetate consists of Rhodamine 110 (HY-D0817) linked to a peptide chain through a cleavable bond. Cleavable bond cleavage enhances fluorophore intensity. D-Leu-Pro-Arg-Rh110-D-Pro acetate can be used to detect FXIa activity .

HY-P6023A

D-Leu-Pro-Arg-Rh110-D-Pro TFA	Factor Xa	Cardiovascular Disease
D-Leu-Pro-Arg-Rh110-D-Pro TFA is a substrate for Factor Xa I (FXIa) with binding affinity. D-Leu-Pro-Arg-Rh110-D-Pro TFA consists of Rhodamine 110 (HY-D0817) linked to a peptide chain through a cleavable bond. Cleavable bond cleavage enhances fluorophore intensity. D-Leu-Pro-Arg-Rh110-D-Pro TFA can be used to detect FXIa activity .

Cat. No.	Product Name		Classification

HY-151720

Cy5.5 DBCO		DBCO
Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .

HY-151751

BDP TMR alkyne		Labeling and Fluorescence Imaging
BDP TMR alkyne is an alkyne-containing click chemistry reagent that can click chemistry with azides. BDP TMR alkyne has the fluorophore BDP and can be used for oligonucleotide labeling and amino acid sequencing .

HY-D2171A

AF488 DBCO ditriethylamine		DBCO
AF488 DBCO ditriethylamine is the ditriethylamine salt form of AF488 DBCO (HY-D2171). AF488 DBCO ditriethylamine is a fluorescent dye that labels azide-containing biomolecules. DBCO is the bioorthogonal partner of azide that allows covalent coupling in the absence of copper. AF488 is a bright, photostable green fluorophore. AF488 exhibits the λ_em and λ_ex wavelength of 520 nm and 470 nm, respectively .

HY-D2219

Sulfo-Cy7 tetrazine		Tetrazine
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .

HY-151712

Sulfo-Cy5-Methyltetrazine		Tetrazine Labeling and Fluorescence Imaging
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

HY-D2171

AF488 DBCO		DBCO
AF488 DBCO is a fluorescent dye that labels azide-containing biomolecules. DBCO is the bioorthogonal partner of azide that allows covalent coupling in the absence of copper. AF488 is a bright, photostable green fluorophore. AF488 exhibits the λ_em and λ_ex wavelength of 520 nm and 470 nm, respectively .

HY-151756

diSulfo-Cy3 alkyne		Alkynes Labeling and Fluorescence Imaging
diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an alkyne group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase .

HY-151728

Trisulfo-Cy3-Alkyne		Alkynes Labeling and Fluorescence Imaging
Trisulfo-Cy3-Alkyne is a water soluble cyanine linker containing an alkyne group, which enables Click Chemistry to attach trisulfo-Cy3 to various azide-bearing molecules. Trisulfo-Cyanine3 is a fluorophore which is compatible with a wide range of fluorescent scanners, imagers, microscopes, etc. It is a bright and photostable dye and can be easily detected in gels by naked eye in low amounts (nmol). Reagent grade, for research use only . Trisulfo-Cy3-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1349

Bodipy TR alkyne		Alkynes
Bodipy TR alkyneis one of a boron dipyrromethene fluorophore for the ROX (Texas Red) channel. This is a versatile fluorophore that can be used in microscopy, fluorescence polarization measurements, and other applications. This derivative is a terminal alkyne of copper-catalyzed click chemistry.

HY-156302

Coumarin-PEG2-endoBCN		Labeling and Fluorescence Imaging BCN
Coumarin-PEG2-endoBCN is a fluorescent dye containing a coumarin fluorophore and can be used as a click chemistry reagent .

HY-D1069

DBCO-Cy3 DBCO-Sulfo-Cy3		DBCO Labeling and Fluorescence Imaging
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-143702

Fluorescent DOTAP NBD-DOTAP		Cationic Lipids
Fluorescent DOTAP, a cationic lipid, can be used for the research of nucleic acid and protein delivery . Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm).

HY-W440911

DSPE-PEG-Cy5, MW 2000		Pegylated Lipids Fluorescent Lipids
DSPE-PEG-Cy5, MW 2000 a red fluorophore polyPEG with lipid hydrophobic tails. The Cy5 fluorophore is commonly used in applications such as protein and nucleic acid labeling for imaging, flow cytometry, and genomic applications. The dye has an excitation peak at 651 nm and an emission peak at 670 nm.

HY-W440908

DSPE-PEG-Cy3, MW 2000		Pegylated Lipids Fluorescent Lipids
DSPE-PEG-Cy3, MW 2000 is a fluorophore attached PEG lipid. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The dye has an absorption wavelength that peaks around 548-552 nm, and an emission maximum around 562-570 nm.

HY-160277

*DSPE-PEG-Fluor* 594,MW 2000**		Pegylated Lipids Fluorescent Lipids
DSPE-PEG-Fluor 594,MW 2000 is a PEGylated lipid with a DSPE group and a Fluor 594 fluorophore. DSPE is a phospholipid. Fluor 594 is a red water-soluble dye .

HY-160272

*DOPE-PEG-Fluor* 488,MW 2000**		Pegylated Lipids Fluorescent Lipids
DOPE-PEG-Fluor 488, MW 2000 is a PEG lipid, composed of a DOPE phospholipid and a Fluor 488 fluorophore. DOPE is an unsaturated phospholipid. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm .

HY-153846

RNA Aptamer Mango I sodium		Aptamers
RNA Aptamer Mango Ⅰ (sodium) consists of 39 nucleotides and has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore). RNA Aptamer Mango Ⅰ (sodium) can be used to visualize RNA expression or localization in live cells.

HY-160257

DOPE-PEG-BDP FL,MW 5000		Pegylated Lipids Fluorescent Lipids
DOPE-PEG-BDP FL,MW 5000 is a PEG-lipid-dye conjugate consists of a DOPE phospholipid which is an unsaturated phospholipid, a BDP FL fluorophore with featuring excitation and emission maxima at 504 and 514 nm respectively and a large PEG spacer which links the former substance together.

HY-153847

RNA Aptamer Mango ΙΙ sodium		Aptamers
RNA Aptamer Mango Ⅱ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅱ (sodium) has markedly improved fluorescent properties, binding affinities, and salt dependencies.

HY-153848

RNA Aptamer Mango Ⅳ sodium		Aptamers
RNA Aptamer Mango Ⅳ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅳ has markedly improved fluorescent properties, binding affinities, and salt dependencies.

HY-153849

RNA Aptamer Mango Ⅲ sodium		Aptamers
RNA Aptamer Mango Ⅲ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅲ has markedly improved fluorescent properties, binding affinities, and salt dependencies.

HY-160043

AL6 aptamer sodium		Aptamers
AL6 aptamer sodium is a short-chain nucleic acid aptamer chemically synthesized in vitro. AL6 aptamer sodium specifically targets Angiopoietin (Ang) for the specific detection of Ang. The AL6 aptamer binds to Ang, causing the rotational motion of the fluorophore on the AL6 aptamer to become slower. The concentration of Ang in the test solution can be quantified by detecting the anisotropy of AL6 aptamer/Ang .

HY-153845

RNA Aptamer Broccoli sodium		Aptamers
RNA Aptamer Broccoli (sodium) is a 49-nt-long aptamer that is substantially shorter than Spinach and Spinach2 and exhibits bright green fluorescence upon binding DFHBI or DFHBI-1T (soluble analogs of the fluorophore of green fluorescent protein). RNA Aptamer Broccoli (sodium) can be used to visualize RNA expression or localization in live cells. In vitro Broccoli exhibits a similar high folding efficiency as Spinach2, but exhibits markedly lower dependence on magnesium for folding and increased thermostability. Additionally, unlike Spinach2, Broccoli does not require the use of a tRNA scaffold to promote its folding in vivo.

HY-153843

RNA Aptamer Corn sodium		Aptamers
RNA Aptamer Corn (sodium) is a 28-nt-long aptamer that is substantially shorter than Spinach and Spinach2 and exhibits bright red fluorescence upon binding DFHO (a soluble analog of the intrinsic fluorophore of red fluorescent protein), RNA Aptamer Corn (sodium) can be used to visualize RNA expression or localization in live cells which have been soaked with chromophores. The Corn-DFHO does not become appreciably cytotoxic when illuminated. And most importantly, Corn-DFHO exhibits markedly increased photostability compared to other aptamer-chromophore complexes both in vitro and in vivo. (36 nt Corn construct: 5'-GGCGCGAGGAAGGAGGUCUGAGGAGGUCACUGCGCC-3'; A 36-nt RNA construct, comprised of the 28-nt minimal Corn sequence extended proximally with a 4 base-pair stem.)

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