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heterocyclic compounds

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51

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3

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2

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7

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1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W016331
    9H-Carbazol-4-ol

    4-Hydroxycarbazole

    		 Biochemical Assay Reagents Others
    9H-Carbazol-4-ol (4-Hydroxycarbazole) can be used as an aromatic heterocyclic compound with widespread applications in organic synthesis, as well as certain biochemical and physiological effects. 9H-Carbazol-4-ol is a kind of biological materials or organic compounds that are widely used in life science research .
    9H-Carbazol-4-ol
  • HY-119517
    Seclazone

    		Others Inflammation/Immunology
    Seclazone, a heterocyclic compound, possesses anti-inflammatory, analgesic, antipyretic and diuretic properties. Seclazone is orally active .
    Seclazone
  • HY-111986
    Trixolane

    		Others Others
    Trixolane is a heterocyclic organic compound .
    Trixolane
  • HY-W009194
    (R)-(+)-Trityl glycidyl ether

    		Drug Intermediate Infection
    (R)-(+)-Trityl glycidyl ether, a heterocyclic compound, is a precursor that can be used to synthesize glycerophospholipids, as well as compounds with antiviral and antimalarial activities .
    (R)-(+)-Trityl glycidyl ether
  • HY-149173
    CDK-IN-11

    		CDK Cardiovascular Disease
    CDK-IN-11 is a heterocyclic compound that has an action of promoting cardiomyocyte maturation .
    CDK-IN-11
  • HY-N13197
    5,6-Dihydro-6-methyl-2H-pyran-2-one

    		Antibiotic Bacterial Fungal Parasite Infection Inflammation/Immunology Cancer
    5,6-Dihydro-6-methyl-2H-pyran-2-one is a heterocyclic compound with antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antibiotic, antituberculosis, antiparasitic, antiviral activities .
    5,6-Dihydro-6-methyl-2H-pyran-2-one
  • HY-W011579
    4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone

    		Biochemical Assay Reagents Others
    4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone, is a heterocyclic compound with a five-membered ring structure, which can be used as a starting material for organic synthesis, a reagent for organic transformation, and a biological probe for studying biological processes. 4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone is a biomaterial or organic compound that can be used as a research-related biomaterial or organic compound in life sciences .
    4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone
  • HY-D0910
    5-Bromo-6-chloro-1H-indol-3-yl acetate

    		Biochemical Assay Reagents Others
    5-Bromo-6-chloro-1H-indol-3-yl acetate, a member of the indole family, is a derivative of the aromatic heterocyclic compound indole. It has been used in a variety of research settings, including studies of enzyme kinetics and protein-ligand interactions. 5-Bromo-6-chloro-1H-indol-3-yl acetate is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research .
    5-Bromo-6-chloro-1H-indol-3-yl acetate
  • HY-N9998
    Hirudonucleodisulfide A

    		Others Others
    Hirudonucleodisulfide A is a heterocyclic compound that can be found in Whitmania pigra. Hirudonucleodisulfide A shows moderately anti-anoxic activity .
    Hirudonucleodisulfide A
  • HY-N10000
    Hirudonucleodisulfide B

    		Others Others
    Hirudonucleodisulfide B is a heterocyclic compound that can be found in Whitmania pigra. Hirudonucleodisulfide B shows moderately anti-anoxic activity .
    Hirudonucleodisulfide B
  • HY-137452
    Suntinorexton

    		Orexin Receptor (OX Receptor) Neurological Disease
    Suntinorexton, a heterocyclic compound, is an orexin type 2 receptor agonist extracted from patent WO2019027058A1, page 288 .
    Suntinorexton
  • HY-W079315
    5-Phenylthieno[2,3-d]pyrimidin-4-amine

    		Parasite Infection
    5-Phenylthieno[2,3-d]pyrimidin-4-amine (Compound 3b) is a heterocyclic compound with antiviral and antiprotozoal activities .
    5-Phenylthieno[2,3-d]pyrimidin-4-amine
  • HY-W018800
    4(3H)-Quinazolinone
    1 Publications Verification

    		 Bacterial EGFR Infection Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology Cancer
    4(3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities .
    4(3H)-Quinazolinone
  • HY-142487
    KRAS G12C inhibitor 32

    		Ras Cancer
    KRAS G12C inhibitor 32, an eight membered heterocyclic compound containing N, is a potent KRAS G12C inhibitor .
    KRAS G12C inhibitor 32
  • HY-W014120
    Thianthrene

    		Others Infection
    Thianthrene, a sulfur-containing heterocyclic compound, is a derivative of dithiin. Thianthrene can be used in the research of dermal infections, in which it interferes with enzyme and nucleic acid function .
    Thianthrene
  • HY-103656
    Tetraphenylporphyrin

    TPP; Tetraphenylporphine; meso-Tetraphenylporphyrin

    		 Others Cancer
    Tetraphenylporphyrin (TPP) is a symmetrically substituted porphyrin-based?heterocyclic compound and used as a structural block for supramolecular?synthesis. Tetraphenylporphyrin derivatives can be used for cancer research .
    Tetraphenylporphyrin
  • HY-W013409
    2,4-Dichlorobenzenesulfonyl chloride

    		Bacterial Infection Cancer
    2,4-Dichlorobenzenesulfonyl chloride (Compound 6d) is a heterocyclic building block, which can be used in the synthesis of nicotinyl arylsulfonylhydrazides with anticancer and antibacterial activities .
    2,4-Dichlorobenzenesulfonyl chloride
  • HY-W017289
    4,4′-Dipyridyl

    		Biochemical Assay Reagents Others
    4,4′-Dipyridyl is a heterocyclic compound that is used as a building block in many materials and compounds. 4,4′-Dipyridyl is utilized as an electronic and photosensitive building block and bidentate ligand in supramolecular chemistry .
    4,4′-Dipyridyl
  • HY-Y0061
    Oxindole
    2 Publications Verification

    2-Indolinone

    		 HIV Endogenous Metabolite Infection Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology Cancer
    Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.
    Oxindole
  • HY-136476E
    Cr(III) protoporphyrin IX

    		Others Others
    Cr(III) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Cr(III) protoporphyrin IX
  • HY-136476F
    Cd(II) protoporphyrin IX

    		Others Others
    Cd(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Cd(II) protoporphyrin IX
  • HY-136476G
    Pt(II) protoporphyrin IX

    		Others Others
    Pt(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Pt(II) protoporphyrin IX
  • HY-121699
    Kibdelone B

    		Biochemical Assay Reagents Infection Metabolic Disease
    Kibdelone B (Compound 2) is a bioactive heterocyclic polyketide that is found in Kibdelosporangium sp. Kibdelone B and C undergo a facile equilibration to Kibdelones A-C under mild conditions .
    Kibdelone B
  • HY-Y0410
    2-Aminobenzimidazole

    2-Iminobenzimidazoline; 1H-Benzimidazol-2-ylamine; 2-Benzimidazolamine

    		 Biochemical Assay Reagents Others
    2-Aminobenzimidazole (2-Iminobenzimidazoline; 1H-Benzimidazol-2-ylamine; 2-Benzimidazolamine) is a heterocyclic aromatic compound. 2-Aminobenzimidazole is a kind of biological materials or organic compounds that are widely used in life science research .
    2-Aminobenzimidazole
  • HY-116943
    MTC420

    		Bacterial Infection
    MTC420 (compound 42a) is a heterocyclic quinolone compound that targets the respiratory chain of Mycobacterium tuberculosis and exhibits antituberculosis activity (Rep Mtb: IC50=525 nM, Wayne Mtb: IC50=76 nM, MDR Mtb: IC50=140 nM) .
    MTC420
  • HY-147604
    Factor B-IN-2

    		Complement System Inflammation/Immunology
    Factor B-IN-2 (Example 1 target compound) is a potent complement factor B inhibitor, with an IC50 of 1.5 μM. Factor B-IN-2 can be used for the research of diseases related to inflammation and immunity .
    Factor B-IN-2
  • HY-147605
    Factor B-IN-3

    		Complement System Inflammation/Immunology
    Factor B-IN-3 (Example 3 target compound) is a potent complement factor B inhibitor. Factor B-IN-3 can be used for the research of diseases related to inflammation and immunity .
    Factor B-IN-3
  • HY-147606
    Factor B-IN-4

    		Complement System Inflammation/Immunology
    Factor B-IN-4 (Example 13 target compound) is a potent complement factor B inhibitor, with an IC50 of 1 μM. Factor B-IN-4 can be used for the research of diseases related to inflammation and immunity .
    Factor B-IN-4
  • HY-147607
    Factor B-IN-5

    		Complement System Inflammation/Immunology
    Factor B-IN-5 (Example 5 target compound) is a potent complement factor B inhibitor, with an IC50 of 1.2 μM. Factor B-IN-5 can be used for the research of diseases related to inflammation and immunity .
    Factor B-IN-5
  • HY-W014120R
    Thianthrene (Standard)

    		Others Infection
    Thianthrene (Standard) is the analytical standard of Thianthrene. This product is intended for research and analytical applications. Thianthrene, a sulfur-containing heterocyclic compound, is a derivative of dithiin. Thianthrene can be used in the research of dermal infections, in which it interferes with enzyme and nucleic acid function .
    Thianthrene (Standard)
  • HY-W001132
    Indole
    1 Publications Verification

    		 Endogenous Metabolite Infection
    Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .
    Indole
  • HY-D1343
    DMNPE-caged D-luciferin

    		Fluorescent Dye
    DMNPE-caged D-luciferin is a heterocyclic luminescent compound that is a natural ligand for luciferase, an enzyme used to detect cell activity. Its reaction requires ATP and emits yellow-green light with a peak wavelength of about 530 nm. The luciferin in the DMNPE cage easily crosses the cell membrane.
    DMNPE-caged D-luciferin
  • HY-143583
    ATX inhibitor 10

    		Phosphodiesterase (PDE) Neurological Disease Cancer
    ATX inhibitor 10 is a potent inhibitor of ATX. ATX inhibitor 10 is s nitrogen-containing heterocyclic compound. ATX plays a role in causing pathological conditions including fibrosis, arthritis, neurodegeneration, neuropathic pain, and cancer. ATX inhibitor 10 has the potential for the research of ATX related diseases (extracted from patent WO2021115375A1, compound 35) .
    ATX inhibitor 10
  • HY-145657
    Benzoquinoquinoxaline

    BQQ

    		 Others Others
    Benzoquinoquinoxaline (BQQ) is a heterocyclic compound with an aminoalkyl side chain. Benzoquinoquinoxaline preferentially binds to DNA triplex structures, intercalates between the bases, thus, stabilising the triplex conformation. Conjugation of Benzoquinoquinoxaline to 1,10-phenanthroline specifically binds and cleaves double strand DNA at the site of formation of a triplex structure .
    Benzoquinoquinoxaline
  • HY-W001663
    4'-Hydroxy-3'-methylacetophenone

    		Bacterial Infection
    4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .
    4'-Hydroxy-3'-methylacetophenone
  • HY-40294
    Indazole

    		Monoamine Oxidase GSK-3 LRRK2 Cardiovascular Disease Neurological Disease Cancer
    Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases .
    Indazole
  • HY-W840250
    3,5-Dimethyl-4-phenylisoxazole

    3,5-Dimethyl-4-phenyl-1,2-oxazole

    		 Fungal Infection Inflammation/Immunology Cancer
    3,5-Dimethyl-4-phenylisoxazole (3,5-Dimethyl-4-phenyl-1,2-oxazole) is a heterocyclic compound that serves as a molecular structural unit, exhibiting anti-inflammatory, anti-tumor, anti-bacterial, and anti-fungal properties, along with the capacity to modulate the immune system.
    3,5-Dimethyl-4-phenylisoxazole
  • HY-W001132R
    Indole (standard)

    		Endogenous Metabolite Infection
    Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .
    Indole (standard)
  • HY-W007355
    Skatole
    5 Publications Verification

    3-Methylindole; 3-Methyl-1H-indole

    		 Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Apoptosis Others
    Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .
    Skatole
  • HY-N6856
    4-Hydroxycoumarin

    		Bacterial Endogenous Metabolite Infection Cancer
    4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .
    4-Hydroxycoumarin
  • HY-160562
    PROTAC ERα Degrader-7

    		PROTACs Estrogen Receptor/ERR Cancer
    PROTAC ERα Degrader-7 (compound i-320) is a potent estrogen receptor alpha(ERα) PROTAC degrader with a DC50 value of 0.000006 µM. PROTAC ERα Degrader-7 comprises a cereblon-binding moiety LBM linked to a ligand ERBM that binds ERα and comprises a benzofused partially saturated 6-membered carbocyclic or heterocyclic ring .
    PROTAC ERα Degrader-7
  • HY-D0827
    Cy2

    Cyanine2

    		 Fluorescent Dye Others
    Cyanines are formally compounds with two nitrogen atoms linked by an odd number of methene units. 26 28 The nitrogen atoms are parts of the heterocyclic units (such as indole, benzoxazol, or benzothiazol) . The structures and optical properties of representative cyanine dyes used for in vivo imaging are presented . Cyanines are characterized by long wavelength, tunable absorption and emission, very high extinction coefficient (up to 300,000 M 1 cm 1), good water solubility, and relatively straightforward synthesis .
    Cy2
  • HY-76779
    4-(Chloromethyl)-7-hydroxycoumarin

    		Others Cancer
    4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .
    4-(Chloromethyl)-7-hydroxycoumarin
  • HY-W016568
    Isoxanthopterin

    		Others Others
    Isoxanthopterin is a heterocyclic compound belonging to the pteridine family and its activity is mainly reflected in its optical properties. Isoxanthopterin can form a reflective layer in the eyes of animals, enhancing visual function. The main regulatory mechanism of isoxanthopterin involves its ability to form a crystalline structure within organisms, which achieves a high refractive index through specific hydrogen bonding patterns and molecular arrangements. Isoxanthopterin can be used for research in materials science and optical engineering .
    Isoxanthopterin
  • HY-W007355R
    Skatole (Standard)

    		Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Apoptosis Others
    Skatole (Standard) is the analytical standard of Skatole. This product is intended for research and analytical applications. Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .
    Skatole (Standard)
  • HY-N6856R
    4-Hydroxycoumarin (Standard)

    		Bacterial Endogenous Metabolite Infection Cancer
    4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .
    4-Hydroxycoumarin (Standard)
  • HY-15350
    Trovirdine hydrochloride

    LY 300046 hydrochloride

    		 Reverse Transcriptase Others
    Trovirdine hydrochloride, a phenethylthiazolylthiourea (PETT) derivative, is an HIV reverse transcriptase (RT) non-nucleoside inhibitor (NNI). A novel computer model of the RT/NNI binding pocket revealed spatial gaps around Trovirdine hydrochloride's pyridyl ring. Docking studies suggested that replacing this planar ring with a nonplanar piperidinyl or piperazinyl ring could better occupy the binding pocket, enhancing anti-HIV activity. Synthesized heterocyclic compounds based on this modification demonstrated greater potency than Trovirdine hydrochloride, effectively inhibiting HIV replication at nanomolar concentrations without cytotoxicity in infected peripheral blood mononuclear cells .
    Trovirdine hydrochloride
  • HY-D0837
    Imidazole
    2 Publications Verification

    Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene

    		 Ser/Thr Protease Thrombopoietin Receptor Neurological Disease Inflammation/Immunology
    Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .
    Imidazole
  • HY-D0837R
    Imidazole (Standard)

    		Ser/Thr Protease Thrombopoietin Receptor Neurological Disease Inflammation/Immunology
    Imidazole (Standard) is the analytical standard of Imidazole. This product is intended for research and analytical applications. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CLPro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .
    Imidazole (Standard)
  • HY-W699983
    Imidazole-15N2

    Glyoxaline-15N2; 1,3-Diaza-2,4-cyclopentadiene-15N2

    		 Isotope-Labeled Compounds Thrombopoietin Receptor Ser/Thr Protease Neurological Disease Inflammation/Immunology
    Imidazole- 15N2 (Glyoxaline- 15N2) is 15N labeled Imidazole. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .
    Imidazole-15N2

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