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protect amino acids

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68

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1

Biochemical Assay Reagents

25

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3

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1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-42222
    N1,N5-Bis-boc-spermidine

    		Biochemical Assay Reagents Others
    N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    N1,N5-Bis-boc-spermidine
  • HY-WAA0302
    1,4-Bis-boc-1,4,7-triazaheptane

    		Biochemical Assay Reagents Others
    1,4-Bis-Boc-1,4,7-triazaheptane is a PEG derivative containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    1,4-Bis-boc-1,4,7-triazaheptane
  • HY-78933
    Fmoc-MMAE

    		Microtubule/Tubulin ADC Cytotoxin Cancer
    Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC .
    Fmoc-MMAE
  • HY-I1111S
    Fmoc-L-Val-OH-d8

    		Isotope-Labeled Compounds Others
    Fmoc-L-Val-OH-d8 is a deuterium labeled Fmoc-L-Val-OH. Fmoc-L-Val-OH is a kind of protect amino acids[1].
    Fmoc-L-Val-OH-d8
  • HY-42213
    N1,N4-Bis-Boc-spermidine

    		Biochemical Assay Reagents Others
    N1,N4-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    N1,N4-Bis-Boc-spermidine
  • HY-W154175
    Boc-DODA

    		Biochemical Assay Reagents Others
    Boc-DODA is a linker containing a Boc-protected amino group and a terminal amine. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    Boc-DODA
  • HY-W591971
    5-((tert-Butoxycarbonyl)amino)pentyl 4-methylbenzenesulfonate

    		Biochemical Assay Reagents Others
    5-((tert-Butoxycarbonyl)amino)pentyl 4-methylbenzenesulfonate is a PEG linker containing a Boc protected amine and a tosyl group. The protected amine can be deprotected under mild acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
    5-((tert-Butoxycarbonyl)amino)pentyl 4-methylbenzenesulfonate
  • HY-W190761
    Amino-PEG11-t-butyl ester

    		Biochemical Assay Reagents Others
    Amino-PEG11-t-butyl ester is a click chemistry linker containing an amine and a t-butyl ester moiety. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
    Amino-PEG11-t-butyl ester
  • HY-106997
    Icofungipen

    BAY 10-8888; PLD 118

    		 Fungal Infection
    Icofungipen is an orally active antifungal agent. Icofungipen is the representative of beta amino acids, is toxic against Candida species. Icofungipen protects infected mice survival from C. albicans infection .
    Icofungipen
  • HY-W190904
    2-Amino-1,3-bis(tert-butyldimethylsilanoxy)propane

    		Biochemical Assay Reagents Others
    2-Amino-1,3-bis(tert-butyldimethylsilanoxy)propane has a TBDMS, acid labile protecting group. TBDMS is used for the protection of alcohol groups. The primary amine is able to react with carboxylic acids, active NHS esters and other carbonyl compounds.
    2-Amino-1,3-bis(tert-butyldimethylsilanoxy)propane
  • HY-W009749
    L-Cystathionine

    		Endogenous Metabolite Apoptosis Cardiovascular Disease
    L-Cystathionine is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine plays an important role in cardiovascular protection .
    L-Cystathionine
  • HY-W009749C
    L-Cystathionine dihydrochloride

    		Endogenous Metabolite Apoptosis Cardiovascular Disease
    L-Cystathionine (dihydrochloride) is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine (dihydrochloride) protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine (dihydrochloride) plays an important role in cardiovascular protection .
    L-Cystathionine dihydrochloride
  • HY-W039729
    5-(Boc-amino)-1-pentanol

    		Biochemical Assay Reagents Others
    5-(Boc-amino)-1-pentanol is a linker containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    5-(Boc-amino)-1-pentanol
  • HY-W092176
    1,9-Bis-boc-1,5,9-triazanonane

    		Biochemical Assay Reagents Others
    1,9-Bis-Boc-1,5,9-triazanonane is a linker containing two Boc-protected amino groups. The Boc groups can be deprotected under mild acidic conditions to form the free amines.
    1,9-Bis-boc-1,5,9-triazanonane
  • HY-W092344
    1,5-Bis-boc-1,5,9-triazanonane

    		Biochemical Assay Reagents Others
    1,5-Bis-Boc-1,5,9-triazanonane is a linker containing two Boc-protected amino groups and a terminal amine. The Boc groups can be deprotected under mild acidic conditions to form the free amines. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    1,5-Bis-boc-1,5,9-triazanonane
  • HY-W190905
    N4,N9-di-Boc-spermine

    		Biochemical Assay Reagents Others
    N4, N9-di-Boc-spermine is a spermine linker containing two a Boc-protected amino groups and two amine groups. The Boc groups can be deprotected under mild acidic conditions to form the free amine. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Spermidine is a polyamine that modulates various cellular activities like cellular development and differentiation, stability of DNA, and apoptosis.
    N4,N9-di-Boc-spermine
  • HY-W598191
    tert-Butyl (3-azidopropyl)carbamate

    		Biochemical Assay Reagents Others
    tert-Butyl (3-azidopropyl)carbamate is a reagent containing an azide group and Boc-protected amino group. It is reactive with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    tert-Butyl (3-azidopropyl)carbamate
  • HY-W008876
    Fmoc-Pen(Trt)-OH

    		Amino Acid Derivatives Others
    Fmoc-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize the inhibitory cystine knot (ICK) peptide ProTx-II .
    Fmoc-Pen(Trt)-OH
  • HY-W019032
    Fmoc-D-Dab(Boc)-OH

    		Amino Acid Derivatives Others
    Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity .
    Fmoc-D-Dab(Boc)-OH
  • HY-W009118
    Fmoc-5-Ava-OH

    		Amino Acid Derivatives Others
    Fmoc-5-Ava-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize fatty acid-based dimeric peptides with PSD-95 inhibitory activity .
    Fmoc-5-Ava-OH
  • HY-W097054
    Fmoc-L-cysteic acid

    		Amino Acid Derivatives Others
    Fmoc-L-cysteic acid is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize triarylsulfonium compounds for radiolabeling of peptides .
    Fmoc-L-cysteic acid
  • HY-W088100
    Boc-N-gamma-trityl-D-asparagin

    N-Boc-N'-trityl-D-asparagine; Boc-D-Asn(Trt)-OH

    		 Amino Acid Derivatives Cancer
    Boc-N-gamma-trityl-D-asparagin (N-Boc-N'-trityl-D-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize metastasis-inhibiting or tumor growth-inhibiting metastasis-inhibiting MS derivatives .
    Boc-N-gamma-trityl-D-asparagin
  • HY-W089230
    Boc-His(Boc)-OH

    N,N'-Di-tert-butoxycarbonyl-L-histidine

    		 Amino Acid Derivatives Others
    Boc-His(Boc)-OH (N,N'-Di-tert-butoxycarbonyl-L-histidine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize the dodecapeptide α-mating factor of Saccharomyces cerevisiae .
    Boc-His(Boc)-OH
  • HY-W010922
    Fmoc-Dap(Boc)-OH

    		Amino Acid Derivatives Others
    Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists .
    Fmoc-Dap(Boc)-OH
  • HY-W101495
    Boc-Leu-OH hydrate

    N-Boc-L-leucine monohydrate

    		 Amino Acid Derivatives Others
    Boc-Leu-OH hydrate (N-Boc-L-leucine monohydrate) is an amino acid derivative with a Boc protecting group, which can be used to synthesize L-prolyl-L-leucyl-glycinamide peptide, a peptide mimetic with dopamine receptor modulatory activity .
    Boc-Leu-OH hydrate
  • HY-W101889
    Boc-Gln(Xan)-OH

    N-Boc-N'-xanthyl-L-glutamine

    		 Amino Acid Derivatives Others
    Boc-Gln(Xan)-OH (N-Boc-N'-xanthyl-L-glutamine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antigenic activity .
    Boc-Gln(Xan)-OH
  • HY-W089233
    Boc-D-Glu-OtBu

    N-Boc-D-glutaMic acid 1-tert-butyl ester

    		 Amino Acid Derivatives Others
    Boc-D-Glu-OtBu (N-Boc-D-glutaMic acid 1-tert-butyl ester) is an amino acid derivative with a Boc protecting group, which can be used to synthesize Adamant-1-yl tripeptide with immunostimulatory activity .
    Boc-D-Glu-OtBu
  • HY-W008064
    Fmoc-Cit-OH

    Fmoc-L-Citrulline

    		 Amino Acid Derivatives Cancer
    Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif .
    Fmoc-Cit-OH
  • HY-W010835
    Boc-D-Cys(Trt)-OH

    Boc-S-trityl-D-cysteine

    		 Amino Acid Derivatives Others
    Boc-D-Cys(Trt)-OH (Boc-S-trityl-D-cysteine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize the bicyclic depsipeptide histone deacetylase inhibitor spirocysteine .
    Boc-D-Cys(Trt)-OH
  • HY-W047788
    H-Dab(Boc)-OH

    		Amino Acid Derivatives Others
    H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities .
    H-Dab(Boc)-OH
  • HY-W101935
    N-Boc-D-Arg hydrochloride

    N-Boc-D-arginine hydrochloride

    		 Amino Acid Derivatives Others
    N-Boc-D-Arg hydrochloride (N-Boc-D-arginine hydrochloride) is an amino acid derivative with a Boc protecting group, which can be used to synthesize desmopressin with the effects of improving nocturia, urinary incontinence and enuresis .
    N-Boc-D-Arg hydrochloride
  • HY-W091365
    Boc-Asn(Xan)-OH

    N-Boc-N'-xanthyl-L-asparagine

    		 Amino Acid Derivatives Others
    Boc-Asn(Xan)-OH (N-Boc-N'-xanthyl-L-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize locust fat growth hormone .
    Boc-Asn(Xan)-OH
  • HY-W014692
    Boc-D-2,3-diaminopropionic acid

    N-t-Boc-amino-D-alanine; Boc-D-Dap-OH

    		 Amino Acid Derivatives Others
    Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize a potent NMDA receptor glycine site agonist with GluN2 subunit-specific activity .
    Boc-D-2,3-diaminopropionic acid
  • HY-W077219
    Boc-L-Arg(Mtr)-OH

    Boc-Arg(Mtr)-OH

    		 Amino Acid Derivatives Others
    Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
    Boc-L-Arg(Mtr)-OH
  • HY-W041989
    Fmoc-Oic-OH

    		Amino Acid Derivatives Others
    Fmoc-Oic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg 10]HOE 140, which has bradykinin B1 antagonist activity .
    Fmoc-Oic-OH
  • HY-W106325
    Fmoc-N-Me-D-Trp(Boc)-OH

    		Amino Acid Derivatives Others
    Fmoc-N-Me-D-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize somatostatin-dopamine chimeric analogs .
    Fmoc-N-Me-D-Trp(Boc)-OH
  • HY-W048697
    Fmoc-D-Pen(Trt)-OH

    		Amino Acid Derivatives Others
    Fmoc-D-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize analogs of cyclic lanthionine enkephalin, a δ-opioid receptor selective ligand .
    Fmoc-D-Pen(Trt)-OH
  • HY-W548477
    H-Lys(Fmoc)-OH hydrochloride

    		Amino Acid Derivatives Others
    H-Lys(Fmoc)-OH hydrochloride is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize diacylated GLP-1 derivatives with antidiabetic activity .
    H-Lys(Fmoc)-OH hydrochloride
  • HY-W011156
    Mpa(Trt)

    		Amino Acid Derivatives Others
    Mpa(Trt) is a 3-mercaptopropionic acid derivative containing a trityl protecting group (Trt) and can be used to synthesize compounds with anti-leukemia activity .
    Mpa(Trt)
  • HY-W101305
    Fmoc-Pen(Acm)-OH

    		Amino Acid Derivatives Others
    Fmoc-Pen(Acm)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize chemically modified cyclic peptides containing cell adhesion recognition (CAR) sequences .
    Fmoc-Pen(Acm)-OH
  • HY-W101722
    tert-Butyl (9-aminononyl)carbamate

    		PROTAC Linkers Cancer
    tert-Butyl (9-aminononyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    tert-Butyl (9-aminononyl)carbamate
  • HY-W005828
    9-(Boc-amino)nonanoic acid

    		PROTAC Linkers Cancer
    9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. 9-(Boc-amino)nonanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    9-(Boc-amino)nonanoic acid
  • HY-400345
    tBu-C18 diacid-D-Glu-OtBu

    		Biochemical Assay Reagents Others
    t-butyl-C18-D-Glu-OtBu is comprised of an octadecanedioic acid with a terminal t-butyl ester and a glutamic acid, which is also protected by a terminal t-butyl ester. The t-butyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins.
    tBu-C18 diacid-D-Glu-OtBu
  • HY-W092078
    tert-Butyl (4-iodobutyl)carbamate

    		Biochemical Assay Reagents Others
    tert-Butyl (4-iodobutyl)carbamate is a four carbon linker containing a Boc-protected amino group and an iodine group. The Boc group can be deprotected under mild acidic conditions to form the free amine. Iodine (I) is a very good leaving group for nucleophilic substitution reactions.
    tert-Butyl (4-iodobutyl)carbamate
  • HY-W479025
    Fmoc-DODA hydrochloride

    		Biochemical Assay Reagents Others
    Fmoc-DODA hydrochloride is a linker with an Fmoc-protected amine and a terminal amine group. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    Fmoc-DODA hydrochloride
  • HY-W800828
    Iodoacetamido-PEG3-NHS ester

    		Biochemical Assay Reagents Others
    Iodoacetamido-PEG3-NHS ester is a PEG reagent containing an Iodoacetamide group and a Boc-protected amino group. The iodoacetamide group is an alkylating agent that can be used to bind covalently with the thiol group. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    Iodoacetamido-PEG3-NHS ester
  • HY-W131541
    N-Boc-undecane-1,11-diamine

    		PROTAC Linkers Cancer
    tert-Butyl (11-aminoundecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. tert-Butyl (11-aminoundecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    N-Boc-undecane-1,11-diamine
  • HY-W590588
    Diethyl acetal-PEG4-amine

    		Biochemical Assay Reagents Others
    Diethyl acetal-PEG4-amine is a PEG reagent containing an amino (NH2) group and a terminal diethyl acetal protecting group, which can be deprotected to form the free aldehyde. NH2 group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
    Diethyl acetal-PEG4-amine
  • HY-W286613
    N-Boc-Biocytin

    		Biochemical Assay Reagents Others
    N-Boc-Biocytin is a biotin PEG linker containing a carboxylic group and Boc-protected amine. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The Boc group can be deprotected under acidic condition to obtain the free amine which can be used for further conjugations.
    N-Boc-Biocytin
  • HY-W591964
    t-Boc-aminooxy-pentane-azide

    		Biochemical Assay Reagents Others
    t-Boc-Aminooxy-pentane-azide is a linker containing an azide group and Boc-protected amino group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    t-Boc-aminooxy-pentane-azide

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