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Results for "

quinoxaline

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Akt (1) Antibiotic (4) Apoptosis (3) Bacterial (4) Bcl-2 Family (1) Biochemical Assay Reagents (1) Discoidin Domain Receptor (1) DNA/RNA Synthesis (1) Drug Metabolite (2) Endogenous Metabolite (3) Epigenetic Reader Domain (1) Fluorescent Dye (1) HIV (1) iGluR (2) Isotope-Labeled Compounds (1) JNK (1) PARP (1) Phospholipase (1) Reverse Transcriptase (1) Topoisomerase (1) Virus Protease (1)
By Research Areas:	Cancer (13) Infection (6) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (3)

By Targets:

5-HT Receptor (1)

Akt (1)

Antibiotic (4)

Apoptosis (3)

Bacterial (4)

Bcl-2 Family (1)

Biochemical Assay Reagents (1)

Discoidin Domain Receptor (1)

DNA/RNA Synthesis (1)

Drug Metabolite (2)

Endogenous Metabolite (3)

Epigenetic Reader Domain (1)

Fluorescent Dye (1)

HIV (1)

iGluR (2)

Isotope-Labeled Compounds (1)

JNK (1)

PARP (1)

Phospholipase (1)

Reverse Transcriptase (1)

Topoisomerase (1)

Virus Protease (1)

By Research Areas:

Cancer (13)

Infection (6)

Inflammation/Immunology (2)

Metabolic Disease (3)

Neurological Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153349

2,3-Di(furan-2-yl)quinoxaline	Fluorescent Dye	Others
2,3-Di(furan-2-yl)quinoxaline (Compound 5) is a quinoxaline exhibiting blue fluorescence. 2,3-Di(furan-2-yl)quinoxaline is cell permeable and sufficiently bright at a micromolar concentration (1.5 μM) .

HY-15067

DNQX 5 Publications Verification FG 9041	iGluR	Cancer
DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC₅₀s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively) .

HY-144874

AZ3391	PARP	Neurological Disease Cancer
AZ3391 is a potent inhibitor of PARP. AZ3391 is a quinoxaline derivative. PARP family of enzymes play an important role in a number of cellular processes, such as replication, recombination, chromatin remodeling, and DNA damage repair. AZ3391 has the potential for the research of diseases and conditions occurring in tissues in the central nervous system, such as the brain and spinal cord (extracted from patent WO2021260092A1, compound 23) .

HY-W018677S

Quinoxaline-d4	Antibiotic	Infection
Quinoxaline-d₄ is the deuterium labeled Quinoxaline[1]. Quinoxaline is a chemical compound that acts as an intermediate for anti-tuberculosis agent Pyrazinamide. Quinoxaline presents a structure that is similar to quinolone antibiotics[2].

HY-N7427

2-(2',3',4'-Trihydroxybutyl)quinoxaline	Endogenous Metabolite	Metabolic Disease
2-(2',3',4'-Trihydroxybutyl)quinoxaline is a food metabolite. 2-(2',3',4'-Trihydroxybutyl)quinoxaline can be formed from homoglucans .

HY-W017519

2-Quinoxalinol Quinoxalin-2-one	Others	Others
2-Quinoxalinol (2-hydroxyquinoxaline) is a 2-hydroxylated quinoxaline that possesses photocatalytic activity and interacts with various compounds, such as antioxidant vitamins and aromatic metabolites, including neurotransmitters and the pineal hormone melatonin .

HY-123354

SC 44914	Bacterial	Infection
SC 44914 is a quinoxaline compound with antibacterial effects. SC-44914 has activity against Campylobacter jejuni, C. coli, and Clostridium difficile .

HY-103233

DNQX disodium salt FG 9041 disodium salt	iGluR	Cancer
DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC₅₀s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively) .

HY-143302

Anticancer agent 31	Others	Cancer
Anticancer agent 31 is a 1,3-diphenylurea quinoxaline derivative, and a anticancer agent. Anticancer agent 31 exhibits antitumor acitvity by arresting cell cycle at S phase and inducing apoptosis .

HY-117725

S-2720	HIV Reverse Transcriptase	Infection
S-2720 is a potent inhibitor of both immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and HIV-1 replication. The binding sites of S-2720 and the nonnucleoside compounds overlap. The small pocket in the p66 subunit-BI-RG-587 (HY-10570) complex is most likely the target of S-2720. S-2720 is a quinoxaline derivative, which is promising for research of HIV-1 infection .

HY-136428

Desoxycarbadox	Drug Metabolite	Cancer
Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .

HY-B1340

Carbadox	Bacterial Antibiotic Endogenous Metabolite	Infection
Carbadox is a quinoxaline-di-N-oxide antibiotic compound which is widely fed to nursery-age pigs to control enteric diseases and improve feed efficiency.

HY-W010865

N-Benzylquinine chloride	Biochemical Assay Reagents	Others
N-Benzylquinine (chloride) is an organic compound. N-Benzylquinine is a derivative of quinoxalines with benzyl substituents. N-Benzylquinine salts are beneficial for the production of tetrahydrofuran trans epoxides .

HY-21210

6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-	Bacterial	Infection
6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-, derived from 2,3-Bis(bromomethyl)quinoxaline, shows antibacterial activity .

HY-136428S

Desoxycarbadox-d3	Isotope-Labeled Compounds	Cancer
Desoxycarbadox-d₃ is the deuterium labeled Desoxycarbadox. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound.

HY-B1340S

Carbadox-d3	Bacterial Antibiotic Endogenous Metabolite	Infection
Carbadox-d₃ is the deuterium labeled Carbadox. Carbadox is a quinoxaline-di-N-oxide antibiotic compound which is widely fed to nursery-age pigs to control enteric diseases and improve feed efficiency.

HY-136428R

Desoxycarbadox (Standard)	Drug Metabolite Antibiotic	Cancer
Desoxycarbadox (Standard) is the analytical standard of Desoxycarbadox. This product is intended for research and analytical applications. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .

HY-138806

PAQ	Others	Neurological Disease
PAQ (Compound 4c) is a quinoxaline derivative. PAQ is an orally active neuroprotective agent, which targets dopamine (DA) neurons and activates reticulum endoplasmic ryanodine receptor (RyR) channels, without effects on glia cells .

HY-162088

DW71177	Epigenetic Reader Domain	Inflammation/Immunology
DW71177 is a novel [1,2,4]triazolo[4,3-a] quinoxaline-based potent and BD1-Selective BET inhibitor, and can be used for study of acute myeloid leukemia .

HY-150552

JNK3 inhibitor-2	JNK Discoidin Domain Receptor	Inflammation/Immunology Cancer
JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor with IC₅₀ values of >100, >100, 0.25 µM for JNK1, JNK2, JNK3, respectively. JNK3 inhibitor-2 shows DDR1 and EGFR (T790M, L858R) inhibition .

HY-W028714

2,3-Diphenylquinoxaline-6-carboxylic acid	Others	Others
2,3-Diphenylquinoxaline-6-carboxylic acid is used for end-capping in the synthesis of AB2 monomers, which facilitates the synthesis and chain-end modification of hyperbranched polymers containing alternating quinoxaline and benzoxazole repeating units .

HY-10355

AKT inhibitor VIII Maximum Cited Publications 43 Publications Verification AKTi-1/2	Akt Apoptosis	Metabolic Disease Cancer
AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC₅₀s of 58 nM, 210 nM, and 2119 nM, respectively.

HY-162380

Topoisomerase II inhibitor 18	Topoisomerase	Cancer
Topoisomerase II inhibitor 18 (Compound IV) is a Quinoxaline derivative, which inhibits topoisomerase II with IC₅₀ of 7.5 μM. Topoisomerase II inhibitor 18 inhibits proliferation, cell cycle at S phase and induces apoptosis in PC-3 cells. Topoisomerase II inhibitor 18 reveals antitumor activity against cancer .

HY-125146

BMD4503-2	Others	Others
BMD4503-2 is a quinoxaline derivative with inhibitory activity against LRP5/6-sclerostin interactions. BMD4503-2 restores the activity of the Wnt/β-catenin signaling pathway by competitively binding to the LRP5/6-sclerostin complex. BMD4503-2 can be used in the study of Wnt signaling pathways in bone development, maintenance and osteoporosis .

HY-151292

Antitumor agent-74	DNA/RNA Synthesis	Cancer
Antitumor agent-74 (compound 13da) is a quinoxalines derivative, an antitumor agent. Antitumor agent-74 exhibits more potent efficacy on tumor inhibition, mixed with regioisomer Antitumor agent-75 (HY-151295, compound 14 da) (mriBIQ 13da/14da). mriBIQ 13da/14da attests cell cycle at S phase, inhibits DNA synthesis, and induces mithochondrial apoptosis .

HY-148038

5-HT3 antagonist 5	5-HT Receptor	Neurological Disease
5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT₃ receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT₃ agonist and 2-methyl-5-HT, and shows anti-depressant effect in mice .

HY-169254

sPLA2 inhibitor 2	Phospholipase Virus Protease	Metabolic Disease
sPLA2 inhibitor 2 (compound 6a) is a sPLA2 inhibitor, with IC₅₀ of 0.0475 μM. sPLA2 inhibitor 2 can be used in diabetes research .

HY-143303

Anticancer agent 32	Apoptosis	Cancer
Anticancer agent 32 (compound 2g) is an anticancer agent. Anticancer agent 32 shows anticancer activities, affects cell cycle and induces cell apoptosis. Anticancer agent 32 can be used for the research of cancer .

HY-149009

Bcl-2-IN-9	Bcl-2 Family Apoptosis	Cancer
Bcl-2-IN-9 is a novel proapoptotic Bcl-2 inhibitor with IC₅₀ value of 2.9 μM and low cytotoxic. Bcl-2-IN-9 mediates apoptosis by down-regulating expression of Bcl-2 in cancer cells and has a high selectivity against leukemia cells .

N-Benzylquinine chloride	Biochemical Assay Reagents
N-Benzylquinine (chloride) is an organic compound. N-Benzylquinine is a derivative of quinoxalines with benzyl substituents. N-Benzylquinine salts are beneficial for the production of tetrahydrofuran trans epoxides .

Cat. No.	Product Name	Category	Target	Chemical Structure