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Results for "

reducing sugars

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Akt (1) AMPK (1) Amylases (1) Apoptosis (2) Atg7 (1) Atg8/LC3 (1) Autophagy (2) Bacterial (1) Biochemical Assay Reagents (5) CD38 (2) Cuproptosis (1) Cytochrome P450 (1) Dipeptidyl Peptidase (1) Drug Isomer (1) EGFR (1) Endogenous Metabolite (8) Fluorescent Dye (1) Free Fatty Acid Receptor (1) Insulin Receptor (1) NF-κB (3) P-glycoprotein (1) PGC-1α (2) PI3K (1) PKA (2) PPAR (1) Reactive Oxygen Species (1) SGLT (2)
By Research Areas:	Cancer (8) Cardiovascular Disease (5) Inflammation/Immunology (5) Metabolic Disease (18) Neurological Disease (4)
Oligonucleotides:	Fillers (1) Sweetening Agents (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0237

Atractyloside A 3 Publications Verification	Others	Cardiovascular Disease Others Cancer
Atractyloside A possesses activities such as lowering blood pressure，reducing blood sugar，and anti-tumor effects.

HY-15916

DTE 2 Publications Verification Dithioerythritol; Cleland’s reagent	Biochemical Assay Reagents	Others
DTE (Dithioerythritol) is a sulfur-containing sugar derived from the corresponding 4-carbon monosaccharide erythrose; an epimer of dithiothreitol (DTT). DTE is a thiol reducing agent .

HY-N2024

Maltose 1 Publications Verification	Endogenous Metabolite	Metabolic Disease Cancer
Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria.

HY-109018A

Velagliflozin proline 1 Publications Verification	SGLT	Metabolic Disease
Velagliflozin proline is an oral sodium-glucose cotransporter 2 (SGLT2) inhibitor with antidiabetic activity. Velagliflozin proline reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations .

HY-N0640

Kuromanin chloride 5+ Cited Publications Chrysontemin; Cyanidin 3-O-glucoside chloride	CD38	Neurological Disease Metabolic Disease
Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities .

HY-W073314

2,2,2-Trifluoroethoxyamine hydrochloride O-(2,2,2-Trifluoroethyl)hydroxylamine hydrochloride	Biochemical Assay Reagents	Others
2,2,2-Trifluoroethoxyamine (O-(2,2,2-Trifluoroethyl)hydroxylamine) hydrochloride can be used as an oxime reactant for coupling reactions with reducing sugars .

HY-D1619

Cyanine3 hydrazide dichloride	Fluorescent Dye	Others
Cyanine3 hydrazide dichloride is a carbonyl reactive dye. Cyanine3 hydrazide dichloride allows the labelling of various carbonyl-containing molecules such as antibodies and other glycoproteins after oxidation by periodate, proteins or reducing sugars after oxidative stress or deamination .

HY-124281

9(R)-PAHSA	NF-κB Akt Autophagy PI3K	Others
9(R)-PAHSA is a R-enantiomer of 9-PAHSA. 9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation .

HY-124281A

9(S)-PAHSA	Drug Isomer NF-κB	Others
9(S)-PAHSA is a S-enantiomer of 9-PAHSA. 9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation .

HY-109089

Epeleuton	Others	Others
Epeleuton is a second-generation synthetic n-3 fatty acid derivative that mainly targets the regulation of blood lipids, blood sugar and inflammatory responses. In clinical trials, Epeleuton significantly reduced triglycerides, very low-density lipoprotein cholesterol and total cholesterol without increasing low-density lipoprotein cholesterol levels. Epeleuton also significantly improved glycated hemoglobin (HbA1c) and fasting blood sugar levels. Epeleuton reduces markers of cardiovascular risk and endothelial dysfunction and has the potential to inhibit systemic inflammation and non-alcoholic fatty liver disease .

HY-128530

Tetrathiomolybdate	Cuproptosis	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma .

HY-NP165

Advanced glycation end products	Biochemical Assay Reagents	Metabolic Disease
Advanced glycation end products is a series of stable compounds produced by non-enzymatic reactions of reducing sugars with proteins, lipids or nucleic acids. Advanced glycation end products is often used as a target for evaluating the inhibitory effects of anti-glycosylation compounds .

HY-N0378

D-Mannitol 5+ Cited Publications Mannitol; Mannite	Endogenous Metabolite Apoptosis Adrenergic Receptor PGC-1α PKA	Cardiovascular Disease Metabolic Disease Cancer
D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .

HY-109018B

Velagliflozin proline hydrate 1 Publications Verification	SGLT	Metabolic Disease
Velagliflozin proline hydrate is the clinical form of Velagliflozin (HY-109018). Velagliflozin is an oral sodium-glucose cotransporter 2 (SGLT2) inhibitor with antidiabetic activity. Velagliflozin reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations .

HY-N2024R

Maltose (Standard)	Endogenous Metabolite	Metabolic Disease Cancer
Maltose (Standard) is the analytical standard of Maltose. This product is intended for research and analytical applications. Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria.

HY-B1245

Salsalate 2 Publications Verification Salicylsalicylic acid; Disalicylic acid	Reactive Oxygen Species	Inflammation/Immunology Cancer
Salsalate is a potent antirheumatic drug with oral activity that reduces irritation during gastric absorption and avoids direct inhibition of cyclooxygenase. Salsalate not only has significant anti-inflammatory effects, but also reduces blood sugar levels, improves insulin resistance, and reduces the expression of cytokines. Salsalate can protect mice from metabolic disorders caused by high-fat diet and effectively improve the symptoms of type 2 diabetes, atherosclerosis and non-alcoholic steatohepatitis ^{[2 ]} .

HY-169566

EGFR-IN-146	EGFR AMPK	Metabolic Disease
EGFR-IN-146 is an EGFR inhibitor that can inhibit the EGFR signaling pathway and improve insulin sensitivity by activating the AMPK pathway, which can effectively reduce blood sugar levels and body weight. EGFR-IN-146 has great potential in the study of diabetes and obesity .

HY-N0378R

D-Mannitol (Standard) 5+ Cited Publications Mannitol(Standard); Mannite (Standard)	Endogenous Metabolite Apoptosis Adrenergic Receptor PGC-1α PKA	Cardiovascular Disease Metabolic Disease Cancer
D-Mannitol (Standard) is the analytical standard of D-Mannitol. This product is intended for research and analytical applications. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .

HY-113024R

Pristanic acid (Standard)	Endogenous Metabolite	Metabolic Disease
D-Mannitol (Standard) is the analytical standard of D-Mannitol. This product is intended for research and analytical applications. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .

HY-N0640R

Kuromanin (chloride) (Standard)	CD38	Neurological Disease Metabolic Disease
Kuromanin (chloride) (Standard) is the analytical standard of Kuromanin (chloride). This product is intended for research and analytical applications. Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities .

HY-116956

D-Erythrose	Biochemical Assay Reagents	Others
D-Erythrose is a four-carbon sugar classified as an aldose. D-Erythrose has unique chemical properties that make it an important intermediate in various metabolic pathways, especially in the biosynthesis of amino acids and nucleotides. It also plays a role in the pentose phosphate pathway, which generates reducing equivalents for biosynthetic reactions and cellular defense against oxidative damage.

HY-170569

Cetagliptin	Dipeptidyl Peptidase Cytochrome P450 P-glycoprotein	Metabolic Disease
Cetagliptin is an orally active inhibitor for dipeptidyl peptidase 4 (DPP-4) and CYP2D6 (IC₅₀ of 6 µM). Cetagliptin is a substrate for P-glycoprotein. Cetagliptin reduces the GLP-1 degradation, maintains the level of postprandial blood sugar, and can be used in type 2 diabetes mellitus research .

HY-170796

α-Amylase-IN-11	Amylases	Metabolic Disease
α-Amylase-IN-11 (compound C5f) is an α-Amylase inhibitor (IC₅₀=0.56 μM) that can reduce the sugar level in vivo. α-Amylase-IN-11 has a moderate inhibitory effect on α-glucosidase (α-glucosidase), with IC₅₀=11.03 μM. α-Amylase-IN-11 can significantly reduce the glucose concentration in a mouse model and has the potential for use in diabetes research .

HY-120657

9-PAHSA	Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology
9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation. 9-PAHSA also improved carotid vascular calcification and attenuates cardiac hypertrophy and dysfunction in db/db mice. 9-PAHSA increases the viability of steatosis primary mouse hepatocytes (PMH). 9-PAHSA can be used in research on diabetes, inflammation, and cardiovascular disease .

HY-159944

PPARγ agonist 14	PPAR	Neurological Disease Metabolic Disease Inflammation/Immunology
PPARγ agonist 14 (compound 3) is a PPARy agonist (EC₅₀=2.4 μM) with anti-diabetic activity. PPARγ agonist 14 can improve intracellular glucose uptake, promote insulin release, and lower blood sugar. In addition, PPARγ agonist 14 also improves mitochondrial function, reduces oxidative stress, and inhibits inflammatory factors. PPARγ agonist 14 can be used in the study of neurodegenerative diseases, neuroinflammatory diseases, and other diseases .

HY-W016715

L-Cysteine hydrochloride hydrate 5+ Cited Publications	Endogenous Metabolite NF-κB Insulin Receptor	Neurological Disease Metabolic Disease
L-Cysteine hydrochloride hydrate is an orally active and essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate regulates CBS/H2S pathway, inhibits NF-κB activation and insulin and ghrelin secretion. L-Cysteine hydrochloride hydrate reduces blood sugar, vascular inflammation markers and appetite. L-Cysteine hydrochloride hydrate induces kidney damage. L-Cysteine hydrochloride hydrate can be used in the study of neurological diseases and diabetes .

HY-109692

GPR120 Agonist 5	Free Fatty Acid Receptor	Metabolic Disease Inflammation/Immunology
GPR120 Agonist 5 (compound 12) is an agonist targeting GPR120 (EC₅₀=1.2 μM). GPR120 Agonist 5 promotes the release of glucagon-like 1 (GLP-1) by binding to the GPR120 receptor, which in turn binds to its receptors on pancreatic beta cells, increasing insulin secretion and thereby lowering blood sugar levels. GPR120 Agonist 5 also helps reduce chronic low-grade inflammation, which plays an important role in the pathogenesis of obesity, insulin resistance, and type 2 diabetes. GPR120 Agonist 5 can be used to investigate the mechanism of action of GPR120 in metabolic and inflammatory diseases .

HY-N0538

Xylitol Xylite	Autophagy Endogenous Metabolite Bacterial Atg7 Atg8/LC3	Metabolic Disease Cancer
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .

HY-W010934

3β,5α,6β-Trihydroxycholestane	Biochemical Assay Reagents	Others
3β,5α,6β-Trihydroxycholestane is a steroid that occurs naturally in the body and is also found in certain foods. It belongs to a class of compounds known as cholestanes, which are closely related to the better known cholesterol. This particular compound is formed from cholesterol through a series of enzymatic reactions in the liver and other organs. It has been studied for its potential health benefits, including its ability to reduce inflammation and oxidative stress in the body. Some research suggests that it may also play a role in regulating blood sugar levels and improving insulin sensitivity. Despite these potential benefits, 3β,5α,6β-Trihydroxycholestane is not widely used as a supplement or medicine due to its relatively low content, focus on natural resources and limited research. However, researchers continue to investigate its potential uses and effects on human health.

Cat. No.	Product Name	Type

HY-D1619

Cyanine3 hydrazide dichloride	Fluorescent Dyes/Probes
Cyanine3 hydrazide dichloride is a carbonyl reactive dye. Cyanine3 hydrazide dichloride allows the labelling of various carbonyl-containing molecules such as antibodies and other glycoproteins after oxidation by periodate, proteins or reducing sugars after oxidative stress or deamination .

Cat. No.	Product Name	Type

HY-15916

DTE 2 Publications Verification Dithioerythritol; Cleland’s reagent	Biochemical Assay Reagents
DTE (Dithioerythritol) is a sulfur-containing sugar derived from the corresponding 4-carbon monosaccharide erythrose; an epimer of dithiothreitol (DTT). DTE is a thiol reducing agent .

HY-NP165

Advanced glycation end products	Native Proteins
Advanced glycation end products is a series of stable compounds produced by non-enzymatic reactions of reducing sugars with proteins, lipids or nucleic acids. Advanced glycation end products is often used as a target for evaluating the inhibitory effects of anti-glycosylation compounds .

HY-116956

D-Erythrose	Carbohydrates
D-Erythrose is a four-carbon sugar classified as an aldose. D-Erythrose has unique chemical properties that make it an important intermediate in various metabolic pathways, especially in the biosynthesis of amino acids and nucleotides. It also plays a role in the pentose phosphate pathway, which generates reducing equivalents for biosynthetic reactions and cellular defense against oxidative damage.

D-Erythrose

Carbohydrates

D-Erythrose is a four-carbon sugar classified as an aldose. D-Erythrose has unique chemical properties that make it an important intermediate in various metabolic pathways, especially in the biosynthesis of amino acids and nucleotides. It also plays a role in the pentose phosphate pathway, which generates reducing equivalents for biosynthetic reactions and cellular defense against oxidative damage.

HY-W010934

3β,5α,6β-Trihydroxycholestane	Cell Assay Reagents
3β,5α,6β-Trihydroxycholestane is a steroid that occurs naturally in the body and is also found in certain foods. It belongs to a class of compounds known as cholestanes, which are closely related to the better known cholesterol. This particular compound is formed from cholesterol through a series of enzymatic reactions in the liver and other organs. It has been studied for its potential health benefits, including its ability to reduce inflammation and oxidative stress in the body. Some research suggests that it may also play a role in regulating blood sugar levels and improving insulin sensitivity. Despite these potential benefits, 3β,5α,6β-Trihydroxycholestane is not widely used as a supplement or medicine due to its relatively low content, focus on natural resources and limited research. However, researchers continue to investigate its potential uses and effects on human health.

3β,5α,6β-Trihydroxycholestane

Cell Assay Reagents

3β,5α,6β-Trihydroxycholestane is a steroid that occurs naturally in the body and is also found in certain foods. It belongs to a class of compounds known as cholestanes, which are closely related to the better known cholesterol. This particular compound is formed from cholesterol through a series of enzymatic reactions in the liver and other organs. It has been studied for its potential health benefits, including its ability to reduce inflammation and oxidative stress in the body. Some research suggests that it may also play a role in regulating blood sugar levels and improving insulin sensitivity. Despite these potential benefits, 3β,5α,6β-Trihydroxycholestane is not widely used as a supplement or medicine due to its relatively low content, focus on natural resources and limited research. However, researchers continue to investigate its potential uses and effects on human health.

Atractyloside A 3 Publications Verification	Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Source classification Other Diseases Plants Compositae Disease Research Fields Erythrina sigmoidea Hua	Others
Atractyloside A possesses activities such as lowering blood pressure，reducing blood sugar，and anti-tumor effects.

Maltose 1 Publications Verification	Structural Classification Polysaccharides Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Cancer	Endogenous Metabolite
Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria.

Kuromanin chloride 5+ Cited Publications Chrysontemin; Cyanidin 3-O-glucoside chloride	Structural Classification Classification of Application Fields Source classification Metabolic Disease Plants Moraceae Anthocyans Flavonoids Microorganisms Phenols Polyphenols Disease Research Fields Morus alba Linn.	CD38
Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities .

D-Mannitol Maximum Cited Publications 9 Publications Verification Mannitol; Mannite	Structural Classification Natural Products Microorganisms other families Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Sweeteners Food Research	Endogenous Metabolite Apoptosis Adrenergic Receptor PGC-1α PKA
D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .

Maltose (Standard)	Structural Classification Polysaccharides Source classification Endogenous metabolite Saccharides	Endogenous Metabolite
Maltose (Standard) is the analytical standard of Maltose. This product is intended for research and analytical applications. Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria.

D-Mannitol (Standard) Maximum Cited Publications 9 Publications Verification Mannitol(Standard); Mannite (Standard)	Structural Classification Natural Products Microorganisms other families Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Sweeteners Food Research	Endogenous Metabolite Apoptosis Adrenergic Receptor PGC-1α PKA
D-Mannitol (Standard) is the analytical standard of D-Mannitol. This product is intended for research and analytical applications. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .

D-Erythrose	Microorganisms Source classification	Biochemical Assay Reagents
D-Erythrose is a four-carbon sugar classified as an aldose. D-Erythrose has unique chemical properties that make it an important intermediate in various metabolic pathways, especially in the biosynthesis of amino acids and nucleotides. It also plays a role in the pentose phosphate pathway, which generates reducing equivalents for biosynthetic reactions and cellular defense against oxidative damage.

9-PAHSA	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation. 9-PAHSA also improved carotid vascular calcification and attenuates cardiac hypertrophy and dysfunction in db/db mice. 9-PAHSA increases the viability of steatosis primary mouse hepatocytes (PMH). 9-PAHSA can be used in research on diabetes, inflammation, and cardiovascular disease .

Pristanic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
D-Mannitol (Standard) is the analytical standard of D-Mannitol. This product is intended for research and analytical applications. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .

Cat. No.	Product Name		Classification