Search Result
Results for "
stereoisomers
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W001959
-
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Endogenous Metabolite
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Metabolic Disease
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D-Allothreonine is the D type stereoisomer of Allothreonine. D-Allothreonine is a peptido-lipid derived from bacteria. D-Allothreonine, amide-linked to the D-galacturonic acid, is also a constituent in the polysaccharide .
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- HY-B1871
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Others
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Others
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Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers .
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- HY-N0181A
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9β,10α-Ergosterol
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Endogenous Metabolite
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Metabolic Disease
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Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol (HY-N0181). Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities .
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- HY-15536A
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GRT6005 (1α,4α)stereoisomer
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Opioid Receptor
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Neurological Disease
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Cebranopadol ((1α,4α)stereoisomer) is a stereoisomer of cebranopadol. Cebranopadol is a potent agonist activity on ORL-1.
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- HY-112382
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Others
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Others
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Iso-olomoucine is an inactive stereoisomer of the CDK5 inhibitor olomoucine with IC50 >1 mM .
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- HY-118670A
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Others
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Cardiovascular Disease
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16(R)-Iloprost is a stereoisomer of Iloprost. 16(R)-Iloprost inhibited platelet aggregation with IC50 value of 65 nM .
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- HY-113887A
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11β-PGF1β
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Others
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Endocrinology
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11β-Prostaglandin F1β (11β-PGF1β) is a stereoisomer of PGF1α with inverted C-9 and C-11 hydroxyl groups .
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- HY-118670
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Others
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Cardiovascular Disease
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16(S)-Iloprost is a stereoisomer of Iloprost. 16(S)-Iloprost inhibited platelet aggregation with IC50 value of 3.5 nM, and balanced binding with platelet membrane receptors Kd value of 13.4 nM .
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- HY-114029
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3-Epiquinine; Epivinylquinidine
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Parasite
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Infection
Cardiovascular Disease
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Ep vinyl quinidine (3-Epiquinine) is an epi-vinyl stereoisomer of Quinidine. Quinidine is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine is also a K+ channel blocker with an IC50 of 19.9 μM. Quinidine can be used for malaria research .
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- HY-B1871R
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Others
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Others
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Metolachlor (Standard) is the analytical standard of Metolachlor. This product is intended for research and analytical applications. Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers .
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- HY-15954A
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CGM097 stereoisomer
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Others
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Others
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NVP-CGM097 (stereoisomer) is a stereoisomer of NVP-CGM097, with no special bioactivity. NVP-CGM097 is a potent and selective MDM2 inhibitor.
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- HY-17626C
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(R)-WCK-2349
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Others
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Others
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(R)-Alalevonadifloxacin mesylate is an isomer of Alalevonadifloxacin mesylate (HY-17626B). Alalevonadifloxacin mesylate is a oraly active anti-methicillin-resistant Staphylococcus aureus (MRSA) antibiotic .
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- HY-100587
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- HY-18500
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Others
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Others
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(βS)-β-Hydroxy-L-histidine hydrochloride is a stereoisomer of β-hydroxyhistidine .
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- HY-B1871S
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Isotope-Labeled Compounds
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Others
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Metolachlor-d6 is the deuterium labeled Metolachlor[1]. Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers[2][3].
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- HY-117881
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Opioid Receptor
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Neurological Disease
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CJ-15208 is a potent and selective κ-opioid receptor antagonist with significant opioid activity. CJ-15208 exhibited strong analgesic effects in the warm water tail withdrawal test in mice and was mediated through multiple opioid receptors. The stereoisomers of CJ-15208 exhibited different opioid activity characteristics, for example, one stereoisomer exhibited κ-opioid receptor antagonism, while the other exhibited δ-opioid receptor antagonism. All stereoisomers of CJ-15208 had no significant effects on respiration. The stereoisomers of CJ-15208 did not lead to the development of drug tolerance, which makes it potential in the further development of safe opioid analgesics .
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- HY-121962
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- HY-Y1804
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- HY-W012479
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- HY-N12868
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Others
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Endocrinology
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25-Epi-28-epi-cyasterone (3) is a stereoisomer of cyasterone that can be isolated from Cyathula officinalis .
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- HY-I1060
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(3R)-LS-Isoleucine; L-Allo-isoleucine
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Endogenous Metabolite
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Others
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L-Alloisoleucine is a branched chain amino acid and is a stereo-isomer of L-isoleucine. L-Alloisoleucine is a common constituent of human plasma (albeit at low levels).
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- HY-N10924
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Others
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Others
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Strychnistenolide is a sesquiterpene lactone that can be isolated from the roots of Lindera strychnifolia. Strychnistenolide exists as a single stereoisomer in CHCl3, but exomeric in pyridine .
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- HY-158554
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2-Eec hydrochloride
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Biochemical Assay Reagents
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Others
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2-Ethylethcathinone hydrochloride (2-Eec hydrochloride) is a substituted cathinone (compounds with potential for abuse). 2-Ethylethcathinone hydrochloride is a stereoisomer of 2-fluoroethcathinone .
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- HY-14856A
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iso-PD 0200390 hydrochloride
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Others
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Others
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iso-Atagabalin (iso-PD 0200390) hydrochloride is a stereoisomer of Atagabalin (HY-14856). Atagabalin is a selective GABA (gamma-aminobutyric acid) receptor agonist with antianxiety effect .
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- HY-122294
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Endogenous Metabolite
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Neurological Disease
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Rociverine is an anticholinergic compound with smooth muscle relaxant activity. Rociverine showed different binding modes in five cloned muscarinic receptors. The cis stereoisomer of Rociverine showed a higher affinity change compared to the trans stereoisomer. The (1R,2R) configuration of Rociverine showed significantly higher affinity, even up to 240 times. The (1S,2S) configuration of Rociverine is very important for binding selectivity .
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- HY-10013B
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MK0364 (1R,2R)stereoisomer
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Cannabinoid Receptor
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Others
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Taranabant (1R,2R)stereoisomer is the R-enantiomer of Taranabant. Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist.
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- HY-Y1804S
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- HY-115429
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6R-Leucovorin calcium; (6R)-Folinic acid calcium
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Others
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Metabolic Disease
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Calcium dextrofolinate is a stereoisomer of Calcium folinate. Calcium folinate (Folinic acid calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
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- HY-13030A
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Epigenetic Reader Domain
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Cancer
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(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 potently decreases expression of both BRD4 target genes, whereas (R)-(-)-JQ1 Enantiomer has no effect.
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- HY-I1060S
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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L-Alloisoleucine-d10 is the deuterium labeled L-Alloisoleucine. L-Alloisoleucine is a branched chain amino acid and is a stereo-isomer of L-isoleucine. L-Alloisoleucine is a common constituent of human plasma (albeit at low levels).
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- HY-N9487
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(-)-α-Phellandrene
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Bacterial
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Infection
Inflammation/Immunology
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(R)-(-)-α-Phellandrene ((-)-α-Phellandrene) is an the (R)-(-)-stereoisomer of α-phellandrene. α-phellandrene is an orally active cyclic monoterpene that attenuates inflammatory response, and induces DNA damage .
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- HY-137428
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Biochemical Assay Reagents
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Others
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(S,S)-EDDS is a stereoisomer of EDTA (HY-Y0682), and exhibits ability to chelate metal ions. (S,S)-EDDS exhibits good biodegradability in the environment, and can be used in environmental management and biotechnology .
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- HY-117682
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(+)-Chloramphenicol; Dextramycine; Dextromycetin
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Antibiotic
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Infection
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L-(+)-threo-Chloramphenicol ((+)-Chloramphenicol) is the S,S-stereoisomer of Chloramphenicol (HY-B0239). L-(+)-Threo-chloramphenicol inhibits protein synthesis in reticulocytes. L-(+)-threo-Chloramphenicol also inhibits the oxidative activity of isolated mitochondria .
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- HY-137261
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Others
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Metabolic Disease
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UDP-β-D-glucose disodium is a the stereoisomer of UDP-α-D-glucose. UDP-β-D-glucose disodium is an oligosaccharide that can be used to synthesize glycoproteins and glycolipids. UDP-β-D-glucose disodium can be used as a substrate .
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- HY-I1070
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(R)-Isoleucine
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Others
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Neurological Disease
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D-Isoleucine ((R)-Isoleucine), an isoleucine stereoisomer, is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine .
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- HY-W012479R
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Endogenous Metabolite
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Metabolic Disease
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H-D-Trp-OH (Standard) is the analytical standard of H-D-Trp-OH. This product is intended for research and analytical applications. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.
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- HY-W048718
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Fmoc-D-α-t-butylglycine
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Amino Acid Derivatives
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Others
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Fmoc-D-Tle-OH (Fmoc-D-α-t-butylglycine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize chelating agents that can form a single stereoisomer-enriched form after coordination with metal centers .
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- HY-108437
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Wnt
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Infection
Cancer
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exo-IWR-1, an inactive stereoisomer of Endo-IWR-1, is a negative control of IWR-1 (HY-12238). IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway .
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- HY-W012479S
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- HY-W016733
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H-D-Cit-OH
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Endogenous Metabolite
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Cardiovascular Disease
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D-Citrulline (H-D-Cit-OH) is a stereoisomer of L-citrulline (HY-N0391). D-Citrulline significantly attenuates polymorphonuclear leukocyte (PMN)-induced cardiac contractile dysfunction in the isolated perfused rat heart subjected to ischemia/reperfusion via a non-NO-mediated mechanism .
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- HY-N6935
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HCV
Akt
GLUT
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Infection
Metabolic Disease
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Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .
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- HY-142162A
-
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Others
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Metabolic Disease
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(S,R)-LSN3318839 is the stereoisomer of LSN3318839 (HY-142162). LSN3318839 is an orally active positive modulator of the glucagon-like peptide-1 receptor (GLP-1R). LSN3318839 can increase the secretion of insulin and has the effect of lowering blood sugar .
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- HY-111827
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- HY-117239
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Adrenergic Receptor
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Cardiovascular Disease
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SB-206606, a stereoisomer of BRL 37344, is a potentially specific, beta 3-adrenergic receptor (β3-AR) ligand. The affinity of [3H]SB 206606 is 76 times higher for the β3-AR than for the beta 1/beta 2-adrenergic receptors .
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- HY-W010042
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L-(-)-Glucose
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Others
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Metabolic Disease
Cancer
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L-Glucose (L-(-)-Glucose) is a stereoisomer of D-Glucose (HY-B0389), which does not readily enter the brain. L-Glucose can promote food intake. L-glucose is combined with a fluorescence detector to produce a fluorescent probe that can be used to visualize and characterize cancer cells. L-Glucose also can be used in the research to enhance memory in mice .
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- HY-W012885
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Biochemical Assay Reagents
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Others
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(S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.
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- HY-116096
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15(R)-Prostaglandin E1; 15-Epiprostaglandin E1
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15-PGDH
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Others
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15-epi-PGE1 (15R-Prostaglandin E1; 15-Epiprostaglandin E1) is a stereoisomer of PGE1 (HY-B0131) but with less biological activity . 15-epi-PGE1 is a non-competitive inhibitor for human placental 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) with an IC50 of 170 μM .
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- HY-N6935R
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HCV
Akt
GLUT
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Infection
Metabolic Disease
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Sennidin B (Standard) is the analytical standard of Sennidin B. This product is intended for research and analytical applications. Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .
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- HY-117542
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Histone Methyltransferase
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Neurological Disease
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D595 is a phenylethylamine calcium channel blocker with potent negative inotropic activity. D595 has shown significant efficacy in its corresponding pharmacological studies, especially in inhibiting the uptake of monoamine neurotransmitters. D595 has high affinity in binding to the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET). Structural adjustments of D595, especially changes in the hydroxyl stereochemistry, significantly affect its interaction with the transporters, showing a specific preference for stereoisomers .
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- HY-147105A
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Interleukin Related
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Inflammation/Immunology
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(+)-LRH-1 modulator-1 is a stereoisomer of LRH-1 modulator-1. LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 has anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces the anti-inflammatory cytokine IL-10 and reduces the inflammatory cytokines IL-1b and TNFa .
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- HY-N3021
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Endogenous Metabolite
NF-κB
TNF Receptor
FOXO
Microtubule/Tubulin
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Metabolic Disease
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D-chiro-Inositol is a stereoisomer of inositol that exhibits activities such as improving glucose metabolism, anti-tumor effects, anti-inflammatory properties, and antioxidant activity. D-chiro-Inositol effectively alleviates cholestasis by enhancing bile acid secretion and reducing oxidative stress. D-chiro-Inositol improves insulin resistance, lowers hyperglycemia and circulating insulin levels, reduces serum androgen levels, and ameliorates some metabolic abnormalities associated with X syndrome by mimicking the action of insulin. Additionally, D-chiro-Inositol can induce a reduction in pro-inflammatory factors (such as Nf-κB) and cytokines (such as TNF-α), thereby exerting anti-inflammatory effects. D-chiro-Inositol may be used in the study of liver cirrhosis, breast cancer, type 2 diabetes, and polycystic ovary syndrome .
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Cat. No. |
Product Name |
Type |
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- HY-W012885
-
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Biochemical Assay Reagents
|
(S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W048718
-
Fmoc-D-α-t-butylglycine
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Amino Acid Derivatives
|
Others
|
Fmoc-D-Tle-OH (Fmoc-D-α-t-butylglycine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize chelating agents that can form a single stereoisomer-enriched form after coordination with metal centers .
|
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- HY-W016733
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H-D-Cit-OH
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Endogenous Metabolite
|
Cardiovascular Disease
|
D-Citrulline (H-D-Cit-OH) is a stereoisomer of L-citrulline (HY-N0391). D-Citrulline significantly attenuates polymorphonuclear leukocyte (PMN)-induced cardiac contractile dysfunction in the isolated perfused rat heart subjected to ischemia/reperfusion via a non-NO-mediated mechanism .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W001959
-
-
-
- HY-N0181A
-
-
-
- HY-100587
-
-
-
- HY-Y1804
-
-
-
- HY-W012479
-
-
-
- HY-I1060
-
-
-
- HY-121962
-
-
-
- HY-N12868
-
-
-
- HY-N10924
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-
-
- HY-N9487
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-
-
- HY-I1070
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(R)-Isoleucine
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Microorganisms
Source classification
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Others
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D-Isoleucine ((R)-Isoleucine), an isoleucine stereoisomer, is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine .
|
-
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- HY-W012479R
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-
-
- HY-N6935
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-
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- HY-111827
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-
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- HY-N6935R
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-
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- HY-N3021
-
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Structural Classification
Natural Products
Classification of Application Fields
Source classification
Metabolic Disease
Endogenous metabolite
Disease Research Fields
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Endogenous Metabolite
NF-κB
TNF Receptor
FOXO
Microtubule/Tubulin
|
D-chiro-Inositol is a stereoisomer of inositol that exhibits activities such as improving glucose metabolism, anti-tumor effects, anti-inflammatory properties, and antioxidant activity. D-chiro-Inositol effectively alleviates cholestasis by enhancing bile acid secretion and reducing oxidative stress. D-chiro-Inositol improves insulin resistance, lowers hyperglycemia and circulating insulin levels, reduces serum androgen levels, and ameliorates some metabolic abnormalities associated with X syndrome by mimicking the action of insulin. Additionally, D-chiro-Inositol can induce a reduction in pro-inflammatory factors (such as Nf-κB) and cytokines (such as TNF-α), thereby exerting anti-inflammatory effects. D-chiro-Inositol may be used in the study of liver cirrhosis, breast cancer, type 2 diabetes, and polycystic ovary syndrome .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B1871S
-
|
Metolachlor-d6 is the deuterium labeled Metolachlor[1]. Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers[2][3].
|
-
-
- HY-Y1804S
-
|
D-Lysine-d4 (monohydrochloride) is the deuterium labeled D-Lysine. D-Lysine monohydrochloride is an Lysine stereoisomer which can be used as a component of surfactants[1].
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-
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- HY-I1060S
-
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L-Alloisoleucine-d10 is the deuterium labeled L-Alloisoleucine. L-Alloisoleucine is a branched chain amino acid and is a stereo-isomer of L-isoleucine. L-Alloisoleucine is a common constituent of human plasma (albeit at low levels).
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-
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- HY-W012479S
-
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H-D-Trp-OH-d5 (D-Tryptophan-d5) is the deuterium labeled H-D-Trp-OH. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.
|
-
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