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stones

" in MedChemExpress (MCE) Product Catalog:

24

Inhibitors & Agonists

2

Biochemical Assay Reagents

2

Peptides

12

Natural
Products

1

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N9941

    Endogenous Metabolite Metabolic Disease
    2,8-Dihydroxyadenine, an endogenous metabolite, can cause the formation of urinary crystals and kidney stones. 2,8-Dihydroxyadenine can be used to diagnose adenine phosphoribosyltransferase (APRT) deficiency .
    2,8-Dihydroxyadenine
  • HY-W009156
    Citric acid tripotassium hydrate
    Maximum Cited Publications
    28 Publications Verification

    Potassium citrate monohydrate

    ATP Citrate Lyase HIF/HIF Prolyl-Hydroxylase Bacterial Endogenous Metabolite Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) is the major active ingredient of Garcinia cambogia. Hydroxycitric acid tripotassium hydrate competitively inhibits ATP citrate lyase with weight loss benefits. Hydroxycitric acid tripotassium hydrate effective inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation and anti-tumor effects .
    Citric acid tripotassium hydrate
  • HY-B1295
    Lithium citrate tetrahydrate
    Maximum Cited Publications
    28 Publications Verification

    Litarex tetrahydrate

    ATP Citrate Lyase Bacterial HIF/HIF Prolyl-Hydroxylase Endogenous Metabolite Infection Metabolic Disease Inflammation/Immunology Cancer
    Lithium citrate (Litarex) tetrahydrate is the major active ingredient of Garcinia cambogia. Lithium citrate tetrahydrate competitively inhibits ATP citrate lyase with weight loss benefits. Lithium citrate tetrahydrate effective inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation and anti-tumor effects .
    Lithium citrate tetrahydrate
  • HY-W009156R

    ATP Citrate Lyase HIF/HIF Prolyl-Hydroxylase Bacterial Endogenous Metabolite Infection Metabolic Disease Inflammation/Immunology Cancer
    Citric acid (tripotassium hydrate) (Standard) is the analytical standard of Citric acid (tripotassium hydrate). This product is intended for research and analytical applications. Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) is the major active ingredient of Garcinia cambogia. Hydroxycitric acid tripotassium hydrate competitively inhibits ATP citrate lyase with weight loss benefits. Hydroxycitric acid tripotassium hydrate effective inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation and anti-tumor effects .
    Citric acid (tripotassium hydrate) (Standard)
  • HY-W009203
    L-Cystine dihydrochloride
    2 Publications Verification

    Endogenous Metabolite Apoptosis Keap1-Nrf2 Reactive Oxygen Species Ferroptosis Metabolic Disease Inflammation/Immunology Cancer
    L-Cystine dihydrochloride is the dihydrochloride salt form of L-Cystine (HY-N0394). L-Cystine dihydrochloride elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-cystine dihydrochloride reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine dihydrochloride combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine dihydrochloride is promising for research of cystinuria and kidney stones
    L-Cystine dihydrochloride
  • HY-100956

    Bacterial Infection
    Flurofamide is a potent bacterial urease inhibitor with potential in the treatment of infection induced urinary stones .
    Flurofamide
  • HY-168434

    Urea Transporter Metabolic Disease
    Urease-IN-19 (Compound 3c) is a potent urease inhibitor with an IC50 value of 2.7 µM. Urease-IN-19 is promising for research of kidney stones and stomach ulcers .
    Urease-IN-19
  • HY-161856

    mTOR Fungal Others
    Antifungal agent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide against Monilinia fructicola. Antifungal agent 106 exhibits antifungal activity with an EC50 value of 11.8 mg/L. It affects hyphal growth by disrupting cell membrane integrity, leading to increased membrane permeability and release of intracellular electrolytes. Antifungal agent 106 can be used in research related to brown rot of stone fruits .
    Antifungal agent 106
  • HY-156648A

    Biochemical Assay Reagents Metabolic Disease
    Vamagloxistat (sodium) is glycolate oxidase inhibitor, used to inhibit hyperoxaluria and kidney stones .
    Vamagloxistat sodium
  • HY-156648

    Others Metabolic Disease
    Vamagloxistat is glycolate oxidase inhibitor, used to inhibit hyperoxaluria and kidney stones .
    Vamagloxistat
  • HY-N0190
    Amygdalin
    5 Publications Verification

    Others Cancer
    Amygdalin is a plant glucoside isolated from the stones of rosaceous fruits, such as apricots, peaches, almond, cherries, and plums.
    Amygdalin
  • HY-121745

    Imidoxon; Oxoimidan

    Drug Metabolite Infection
    Phosmet oxon (Imidoxon) is a main and toxic metabolite of phosmet. Phosmet is a cholinesterase inhibitor insecticide used on pome and stone fruits .
    Phosmet oxon
  • HY-N0190R

    Others Cancer
    Amygdalin (Standard) is the analytical standard of Amygdalin. This product is intended for research and analytical applications. Amygdalin is a plant glucoside isolated from the stones of rosaceous fruits, such as apricots, peaches, almond, cherries, and plums.
    Amygdalin (Standard)
  • HY-W017386
    3-Methyl-2-oxovaleric acid sodium
    3 Publications Verification

    Endogenous Metabolite Metabolic Disease
    3-Methyl-2-oxovaleric acid sodium is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid sodium is a biomarker of mustard airway diseases (MADs) and uric acid stone .
    3-Methyl-2-oxovaleric acid sodium
  • HY-113063
    3-Methyl-2-oxovaleric acid
    3 Publications Verification

    Endogenous Metabolite Metabolic Disease
    3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone .
    3-Methyl-2-oxovaleric acid
  • HY-121745R

    Drug Metabolite Infection
    Phosmet oxon (Standard) is the analytical standard of Phosmet oxon. This product is intended for research and analytical applications. Phosmet oxon (Imidoxon) is a main and toxic metabolite of phosmet. Phosmet is a cholinesterase inhibitor insecticide used on pome and stone fruits .
    Phosmet oxon (Standard)
  • HY-139725
    CDK5-IN-1
    1 Publications Verification

    CDK Metabolic Disease
    CDK5-IN-1, a potent CDK5 inhibitor, is against CDK5 activity less than 10 nM. CDK5-IN-1 is used for kidney diseases research .
    CDK5-IN-1
  • HY-W017386S

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    3-Methyl-2-oxovaleric acid-d8 sodium is the deuterium labeled 3-Methyl-2-oxovaleric acid. 3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone .
    3-Methyl-2-oxovaleric acid-d8 sodium
  • HY-113063R

    Endogenous Metabolite Metabolic Disease
    3-Methyl-2-oxovaleric acid (Standard) is the analytical standard of 3-Methyl-2-oxovaleric acid (HY-113063). This product is intended for research and analytical applications. 3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone.
    3-Methyl-2-oxovaleric acid (Standard)
  • HY-Y1117
    Melamine
    1 Publications Verification

    Apoptosis TGF-β Receptor NF-κB COX NADPH Oxidase ROS Kinase Neurological Disease Inflammation/Immunology
    Melamine is an orally active inducer of Apoptosis. Melamine induces animal disease models. Melamine affects the activity of Sertoli cell and can be used for research on male reproductive function. Melamine also has neurotoxicity and nephrotoxicity. Melamine induces cognitive impairment and acute kidney injury models. Melamine can also be used to induce bladder cancer and urinary stone models .
    Melamine
  • HY-Y0708

    Calcium phosphate dihydrate

    Biochemical Assay Reagents Others
    Calcium hydrogen phosphate dihydrate, also known as CHPD or DCPD.Calcium hydrogen phosphate dihydrate can be found quite frequently in urinary calculi stones. Calcium hydrogen phosphate dihydrate can be used as an excipient, such as diluent, adsorbent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Calcium hydrogen phosphate dihydrate
  • HY-W009356

    Endogenous Metabolite Ferroptosis ROS Kinase Keap1-Nrf2 Reactive Oxygen Species Others
    L-Cystine hydrochloride is an orally active extracellular form of L-Cysteine (HY-Y0337), occurring in proteins of plants and animals. L-Cystine hydrochloride elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-Cystine hydrochloride reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine hydrochloride combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine hydrochloride is promising for research of cystinuria and kidney stones
    L-Cystine hydrochloride
  • HY-N0394
    L-Cystine
    2 Publications Verification

    Endogenous Metabolite Ferroptosis ROS Kinase Keap1-Nrf2 Reactive Oxygen Species Metabolic Disease Inflammation/Immunology Cancer
    L-Cystine is an orally active extracellular form of L-Cysteine (HY-Y0337), occurring in proteins of plants and animals. L-Cystine elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-cystine reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine is promising for research of cystinuria and kidney stones
    L-Cystine
  • HY-N0394R

    Endogenous Metabolite Ferroptosis ROS Kinase Keap1-Nrf2 Metabolic Disease Inflammation/Immunology Cancer
    L-Cystine (Standard) is the analytical standard of L-Cystine. This product is intended for research and analytical applications. L-Cystine, the extracellular form of L-Cysteine (HY-Y0337), is a nutritionally dispensable semiessential sulfur-containing amino acid, occurring in proteins of plants and animals. L-Cystine induces Nrf2 protein elevation in a Keap1 (HY-P75897)-dependent manner and activates Nrf2 transcription factor. L-cystine can elicit cytoprotection by reducing ROS generation and protecting against oxidant- or doxorubicin-induced apoptosis. The reduced reabsorption of L-Cystine in renal tubules and its poor solubility in urine are the important causes of cystine precipitation and cystine crystal formation eventually leading to kidney stones. L-Cystine combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine is promising for research of cystinuria and cystinosis
    L-Cystine (Standard)

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