2. Metabolic Enzyme/Protease Apoptosis NF-κB Immunology/Inflammation
  3. Mitochondrial Metabolism Apoptosis Reactive Oxygen Species
  4. TT01001

TT01001 is a potent and orally active mitoNEET ligand. TT01001 reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 improves type II diabetes without causing weight gain.

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TT01001 Chemical Structure

TT01001 Chemical Structure

CAS No. : 1022367-69-6

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5 mg USD 150 In-stock
10 mg USD 250 In-stock
25 mg USD 550 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

TT01001 is a potent and orally active mitoNEET ligand. TT01001 reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 improves type II diabetes without causing weight gain[1][2].

Molecular Weight

376.30

Formula

C15H19Cl2N3O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OCC)N1CCC(CC1)NC(NC2=CC(Cl)=CC(Cl)=C2)=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (332.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6575 mL 13.2873 mL 26.5745 mL
5 mM 0.5315 mL 2.6575 mL 5.3149 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6575 mL 13.2873 mL 26.5745 mL 66.4364 mL
5 mM 0.5315 mL 2.6575 mL 5.3149 mL 13.2873 mL
10 mM 0.2657 mL 1.3287 mL 2.6575 mL 6.6436 mL
15 mM 0.1772 mL 0.8858 mL 1.7716 mL 4.4291 mL
20 mM 0.1329 mL 0.6644 mL 1.3287 mL 3.3218 mL
25 mM 0.1063 mL 0.5315 mL 1.0630 mL 2.6575 mL
30 mM 0.0886 mL 0.4429 mL 0.8858 mL 2.2145 mL
40 mM 0.0664 mL 0.3322 mL 0.6644 mL 1.6609 mL
50 mM 0.0531 mL 0.2657 mL 0.5315 mL 1.3287 mL
60 mM 0.0443 mL 0.2215 mL 0.4429 mL 1.1073 mL
80 mM 0.0332 mL 0.1661 mL 0.3322 mL 0.8305 mL
100 mM 0.0266 mL 0.1329 mL 0.2657 mL 0.6644 mL
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TT01001 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TT010011022367-69-6TT 01001TT-01001Mitochondrial MetabolismApoptosisReactive Oxygen Speciesapoptosisearly brain injurymitochondrial dysfunctionoxidative stresssubarachnoid hemorrhageInhibitorinhibitorinhibit

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